NO20061561L - Aerosolformuleringer for avlevering av dihydroergotamin til den systemiske sirkulasjon via pulmonaer inhalering - Google Patents
Aerosolformuleringer for avlevering av dihydroergotamin til den systemiske sirkulasjon via pulmonaer inhaleringInfo
- Publication number
- NO20061561L NO20061561L NO20061561A NO20061561A NO20061561L NO 20061561 L NO20061561 L NO 20061561L NO 20061561 A NO20061561 A NO 20061561A NO 20061561 A NO20061561 A NO 20061561A NO 20061561 L NO20061561 L NO 20061561L
- Authority
- NO
- Norway
- Prior art keywords
- dihydroergotamine
- aerosol formulations
- delivery
- via pulmonary
- systemic circulation
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000000443 aerosol Substances 0.000 title abstract 3
- HESHRHUZIWVEAJ-JGRZULCMSA-N dihydroergotamine Chemical compound C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@@](C(N21)=O)(C)NC(=O)[C@H]1CN([C@H]2[C@@H](C3=CC=CC4=NC=C([C]34)C2)C1)C)C1=CC=CC=C1 HESHRHUZIWVEAJ-JGRZULCMSA-N 0.000 title abstract 3
- 229960004704 dihydroergotamine Drugs 0.000 title abstract 3
- 230000002685 pulmonary effect Effects 0.000 title abstract 3
- 230000001839 systemic circulation Effects 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 2
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 206010027603 Migraine headaches Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 239000000446 fuel Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007922 nasal spray Substances 0.000 abstract 1
- 229940097496 nasal spray Drugs 0.000 abstract 1
- 239000008249 pharmaceutical aerosol Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000002203 pretreatment Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Farmasøytiske aerosolformuleringer av dihyodroergotamin, eller farmasøytisk akseptable salter av denne, for administrering som tørrpulver eller drivstoff suspensjoner via pulmonar aerosol eller nesespray inhalasjon. Slike formuleringer kan anvendes forbehandling av ulike sykdomsstadier, tilstander, inkludert men ikke begrenset til, migrene hodepine. Dihydroergotamin partiklene produseres ved anvendelse av en superkritisk fiuidprosess. Aerosolformuleringene beskrevet har overlegen stabilitet, renhet og omfatter partikler av innåndbar størrelse særlig egnet for pulmonær avlevering.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50193803P | 2003-09-10 | 2003-09-10 | |
| PCT/US2004/029632 WO2005025506A2 (en) | 2003-09-10 | 2004-09-10 | Aerosol formulations for delivery of dihydroergotamine to the systemic circulation via pulmonary inhalation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20061561L true NO20061561L (no) | 2006-06-09 |
Family
ID=34312325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20061561A NO20061561L (no) | 2003-09-10 | 2006-04-06 | Aerosolformuleringer for avlevering av dihydroergotamin til den systemiske sirkulasjon via pulmonaer inhalering |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20080118442A1 (no) |
| EP (1) | EP1663159A4 (no) |
| JP (2) | JP2007505136A (no) |
| AU (2) | AU2004272077A1 (no) |
| CA (1) | CA2538237A1 (no) |
| NO (1) | NO20061561L (no) |
| WO (1) | WO2005025506A2 (no) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007505136A (ja) * | 2003-09-10 | 2007-03-08 | マツプ・フアーマシユーテイカルズ・インコーポレーテツド | ジヒドロエルゴタミンを肺吸入により体循環に送達するためのエアゾール製剤 |
| KR101179393B1 (ko) * | 2004-03-23 | 2012-09-07 | 노파르티스 아게 | 제약 조성물 |
| CN101262846A (zh) * | 2005-07-15 | 2008-09-10 | Map药物公司 | 在离散的吸入粒子中结合的多种活性药物成分及其制剂 |
| WO2008097664A1 (en) | 2007-02-11 | 2008-08-14 | Map Pharmaceuticals, Inc. | Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile |
| WO2009047935A1 (ja) * | 2007-10-12 | 2009-04-16 | Ono Pharmaceutical Co., Ltd. | 微粒子 |
| AU2009214443B2 (en) | 2008-02-13 | 2013-10-10 | Board Of Regents, The University Of Texas System | Templated open flocs of anisotropic particles for enhanced pulmonary delivery |
| KR20110040844A (ko) * | 2008-07-11 | 2011-04-20 | 맵 파마슈티컬스, 인코포레이티드 | 에어로졸 약물 전달을 위한 용기 |
| US20100291221A1 (en) * | 2009-05-15 | 2010-11-18 | Robert Owen Cook | Method of administering dose-sparing amounts of formoterol fumarate-budesonide combination particles by inhalation |
| WO2010151804A1 (en) * | 2009-06-26 | 2010-12-29 | Map Pharmaceuticals, Inc. | Administration of dihydroergotamine mesylate particles using a metered dose inhaler |
| IN2012DN04858A (no) | 2009-12-23 | 2015-09-25 | Map Pharmaceuticals Inc | |
| KR20140042868A (ko) | 2011-06-23 | 2014-04-07 | 맵 파마슈티컬스, 인코포레이티드 | 신규한 플루오로에르골린 유사체 |
| SG10201509139QA (en) | 2011-12-19 | 2015-12-30 | Map Pharmaceuticals Inc | Novel iso-ergoline derivatives |
| CA2859175A1 (en) | 2011-12-21 | 2013-06-27 | Map Pharmaceuticals, Inc. | Novel neuromodulatory compounds |
| US9012640B2 (en) | 2012-06-22 | 2015-04-21 | Map Pharmaceuticals, Inc. | Cabergoline derivatives |
| EP2934529A1 (en) * | 2012-12-21 | 2015-10-28 | MAP Pharmaceuticals, Inc. | Novel ergoline derivatives and uses thereof |
| AU2013361337A1 (en) | 2012-12-21 | 2015-07-09 | Map Pharmaceuticals, Inc. | 8'-Hydroxy-Dihydroergotamine compounds and compositions |
| CA2895829A1 (en) | 2012-12-21 | 2014-06-26 | Map Pharmaceuticals, Inc. | Novel methysergide derivatives |
| WO2014186754A2 (en) | 2013-05-16 | 2014-11-20 | Board Of Regents The University Of Texas System | Dry solid aluminum adjuvant-containing vaccines and related methods thereof |
| DK3049059T3 (da) | 2013-09-24 | 2022-01-31 | Satsuma Pharmaceuticals Inc | Intranasal dhe formulering til behandlingen af hovedpine |
| JP6712428B2 (ja) | 2014-02-04 | 2020-06-24 | コントラフェクト コーポレイション | インフルエンザ受動免疫に有用な抗体ならびにその使用のための組成物、組合せおよび方法 |
| MX2017009405A (es) | 2015-01-20 | 2018-01-18 | Xoc Pharmaceuticals Inc | Compuestos de tipo ergolina y usos de estos. |
| EP3247357A4 (en) | 2015-01-20 | 2018-07-11 | Xoc Pharmaceuticals, Inc | Isoergoline compounds and uses thereof |
| MX2018002895A (es) | 2015-09-10 | 2018-07-06 | Impel Neuropharma Inc | Dispositivo de administracion nasal en linea. |
| US10112924B2 (en) | 2015-12-02 | 2018-10-30 | Astraea Therapeutics, Inc. | Piperdinyl nociceptin receptor compounds |
| CN108883103A (zh) | 2015-12-02 | 2018-11-23 | 阿斯特来亚治疗有限责任公司 | 哌啶基痛敏肽受体化合物 |
| US10047077B2 (en) | 2016-04-13 | 2018-08-14 | Skyline Antiinfectives, Inc. | Deuterated O-sulfated beta-lactam hydroxamic acids and deuterated N-sulfated beta-lactams |
| US10106521B2 (en) | 2016-11-09 | 2018-10-23 | Phloronol, Inc. | Eckol derivatives, methods of synthesis and uses thereof |
| US10085999B1 (en) | 2017-05-10 | 2018-10-02 | Arixa Pharmaceuticals, Inc. | Beta-lactamase inhibitors and uses thereof |
| WO2018223065A1 (en) | 2017-06-01 | 2018-12-06 | Xoc Pharmaceuticals, Inc. | Ergoline derivatives for use in medicine |
| WO2019118393A1 (en) | 2017-12-11 | 2019-06-20 | Board Of Regents, The University Of Texas System | Dry adjuvanted immune stimulating compositions and use thereof for mucosal administration |
| JP7317020B2 (ja) | 2018-01-05 | 2023-07-28 | インペル ファーマシューティカルズ インコーポレイテッド | 精密嗅覚デバイスによるジヒドロエルゴタミンの鼻腔内送達 |
| US10532049B1 (en) | 2018-08-27 | 2020-01-14 | Pharmaceutical Industries Limited | Parenteral unit dosage form of dihydroergotamine |
| GB201817868D0 (en) * | 2018-11-01 | 2018-12-19 | Nicoventures Trading Ltd | Aerosolised formulation |
| CN120284965A (zh) | 2018-12-11 | 2025-07-11 | 小蜜橘制药公司 | 用于治疗或预防头痛的组合物、装置和方法 |
| GB2581431A (en) * | 2018-12-11 | 2020-08-19 | Satsuma Pharmaceuticals Inc | Compositions, devices, and methods for treating or preventing headaches |
| CN113874080B (zh) | 2019-02-06 | 2024-09-27 | 戴斯阿尔法公司 | Il-17a调节剂及其用途 |
| EP4031534A1 (en) | 2019-09-16 | 2022-07-27 | Dice Alpha, Inc. | Il-17a modulators and uses thereof |
| WO2021133744A1 (en) * | 2019-12-23 | 2021-07-01 | Scienture, Inc. | Dihydroergotamine mesylate formulations and pre-filled injectors for therapeutic delivery of the same |
| US12024521B2 (en) | 2020-06-30 | 2024-07-02 | Prosetta Biosciences, Inc. | Isoquinoline derivatives, methods of synthesis and uses thereof |
| KR20230169979A (ko) | 2021-03-10 | 2023-12-18 | 다이스 몰레큘스 에스브이, 인크. | 알파 v 베타 6 및 알파 v 베타 1 인테그린 억제제 및 그의 용도 |
| CA3236150A1 (en) | 2021-10-22 | 2023-04-27 | Prosetta Biosciences, Inc. | Novel host-targeted pan-respiratory antiviral small molecule therapeutics |
| US20230248724A1 (en) * | 2021-10-29 | 2023-08-10 | Sun Pharmaceutical Industries Limited | Method of Injecting Dihydroergotamine Into The Body |
| US11981694B2 (en) | 2022-01-03 | 2024-05-14 | Lilac Therapeutics, Inc. | Acyclic thiol prodrugs |
| WO2023129577A1 (en) | 2022-01-03 | 2023-07-06 | Lilac Therapeutics, Inc. | Cyclic thiol prodrugs |
| CA3253352A1 (en) | 2022-03-02 | 2023-09-07 | Mitopower, Inc. | NEW PROMEDICINAL PRODUCTS DERIVED FROM NICOTINIC ACID AND RIBOSE |
| GB2619907A (en) | 2022-04-01 | 2023-12-27 | Kanna Health Ltd | Novel crystalline salt forms of mesembrine |
| GB2636969A (en) | 2023-11-24 | 2025-07-09 | Ontrack Therapeutics Ltd | Novel crystalline salt forms |
Family Cites Families (106)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE555319A (no) * | 1956-03-21 | 1900-01-01 | ||
| US2885427A (en) * | 1956-11-15 | 1959-05-05 | Dow Chemical Co | Fluorination of trichloroethylene |
| US3320125A (en) * | 1964-04-28 | 1967-05-16 | Merck & Co Inc | Inhalation aerosol composition |
| GB1200886A (en) * | 1966-09-23 | 1970-08-05 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
| US3809294A (en) * | 1973-06-27 | 1974-05-07 | American Cyanamid Co | Dispensing lung contacting powdered medicaments |
| BE887518A (fr) * | 1980-02-15 | 1981-08-13 | Glaxo Group Ltd | Cartothioates d'androstanes |
| US4311863A (en) * | 1980-06-11 | 1982-01-19 | E. I. Du Pont De Nemours & Company | Process for the manufacture of 1,1,1,2-tetrafluoroethane |
| DE3274065D1 (de) * | 1981-07-08 | 1986-12-11 | Draco Ab | Powder inhalator |
| EP0072046B1 (en) * | 1981-07-24 | 1986-01-15 | FISONS plc | Inhalation drugs, methods for their production and pharmaceutical formulations containing them |
| US4659696A (en) * | 1982-04-30 | 1987-04-21 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition and its nasal or vaginal use |
| JPS5921613A (ja) * | 1982-07-28 | 1984-02-03 | Takeda Chem Ind Ltd | 直腸投与製剤 |
| FI70493C (fi) * | 1982-08-19 | 1986-09-19 | Stroemberg Oy Ab | Vaexelriktare skyddad med avseende pao stighastigheten av stroem och spaenning |
| JPS6037556A (ja) * | 1983-08-10 | 1985-02-26 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
| US4514574A (en) * | 1984-01-09 | 1985-04-30 | The Dow Chemical Company | Process for separating isomeric mixtures |
| GB8432063D0 (en) * | 1984-12-19 | 1985-01-30 | Riker Laboratories Inc | Physically modified steroids |
| GB8501015D0 (en) * | 1985-01-16 | 1985-02-20 | Riker Laboratories Inc | Drug |
| US4737384A (en) * | 1985-11-01 | 1988-04-12 | Allied Corporation | Deposition of thin films using supercritical fluids |
| NZ221411A (en) * | 1986-08-11 | 1989-10-27 | Innovata Biomed Ltd | Pharmaceutical compositions containing microcapsules and a surfactant |
| ATE94782T1 (de) * | 1987-12-21 | 1993-10-15 | Union Carbide Corp | Verwendung von superkritischen fluessigkeiten als verduenner beim aufspruehen von ueberzuegen. |
| US5206268A (en) * | 1988-08-16 | 1993-04-27 | Burroughs Wellcome Co. | Medicaments |
| US5707634A (en) * | 1988-10-05 | 1998-01-13 | Pharmacia & Upjohn Company | Finely divided solid crystalline powders via precipitation into an anti-solvent |
| US5225183A (en) * | 1988-12-06 | 1993-07-06 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| US5776434A (en) * | 1988-12-06 | 1998-07-07 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| US5011678A (en) * | 1989-02-01 | 1991-04-30 | California Biotechnology Inc. | Composition and method for administration of pharmaceutically active substances |
| DE3905726A1 (de) * | 1989-02-24 | 1990-08-30 | Hoechst Ag | Druckgaspackung und treibmittel fuer aerosole |
| CA2058764A1 (en) * | 1989-04-28 | 1990-10-29 | Peter D. Hodson | Dry powder inhalation device |
| GB8909891D0 (en) * | 1989-04-28 | 1989-06-14 | Riker Laboratories Inc | Device |
| US5238920A (en) * | 1989-08-22 | 1993-08-24 | Abbott Laboratories | Pulmonary surfactant protein fragments |
| US5270305A (en) * | 1989-09-08 | 1993-12-14 | Glaxo Group Limited | Medicaments |
| US5178878A (en) * | 1989-10-02 | 1993-01-12 | Cima Labs, Inc. | Effervescent dosage form with microparticles |
| US5223264A (en) * | 1989-10-02 | 1993-06-29 | Cima Labs, Inc. | Pediatric effervescent dosage form |
| US5106659A (en) * | 1989-10-04 | 1992-04-21 | Nordson Corporation | Method and apparatus for spraying a liquid coating containing supercritical fluid or liquified gas |
| US5118494A (en) * | 1990-03-23 | 1992-06-02 | Minnesota Mining And Manufacturing Company | Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations |
| US5126123A (en) * | 1990-06-28 | 1992-06-30 | Glaxo, Inc. | Aerosol drug formulations |
| US5292499A (en) * | 1990-09-11 | 1994-03-08 | University Of Wales College Of Cardiff | Method of preparing medical aerosol formulations including drug dissolved in reverse micelles |
| MX9203481A (es) * | 1990-10-18 | 1992-07-01 | Minnesota Mining & Mfg | Formulaciones. |
| US6006745A (en) * | 1990-12-21 | 1999-12-28 | Minnesota Mining And Manufacturing Company | Device for delivering an aerosol |
| US5290539A (en) * | 1990-12-21 | 1994-03-01 | Minnesota Mining And Manufacturing Company | Device for delivering an aerosol |
| US5190029A (en) * | 1991-02-14 | 1993-03-02 | Virginia Commonwealth University | Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content |
| US5182097A (en) * | 1991-02-14 | 1993-01-26 | Virginia Commonwealth University | Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content |
| US5186164A (en) * | 1991-03-15 | 1993-02-16 | Puthalath Raghuprasad | Mist inhaler |
| US5182040A (en) * | 1991-03-28 | 1993-01-26 | E. I. Du Pont De Nemours And Company | Azeotropic and azeotrope-like compositions of 1,1,2,2-tetrafluoroethane |
| DE4117751A1 (de) * | 1991-05-30 | 1992-12-03 | Bayer Ag | Verfahren zur isolierung von polycarbonaten |
| ATE339952T1 (de) * | 1991-06-10 | 2006-10-15 | Schering Corp | Fluorchlorkohlenwasserstofffreie aerosolformulierungen |
| US6063910A (en) * | 1991-11-14 | 2000-05-16 | The Trustees Of Princeton University | Preparation of protein microparticles by supercritical fluid precipitation |
| IL104068A (en) * | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant |
| US5744123A (en) * | 1991-12-12 | 1998-04-28 | Glaxo Group Limited | Aerosol formulations containing P134a and particulate medicaments |
| CA2455115C (en) * | 1991-12-12 | 2008-05-27 | Glaxo Group Limited | Pharmaceutical aerosol formulation |
| US5736124A (en) * | 1991-12-12 | 1998-04-07 | Glaxo Group Limited | Aerosol formulations containing P134a and particulate medicament |
| US5916540A (en) * | 1994-10-24 | 1999-06-29 | Glaxo Group Limited | Aerosol formulations containing P134A and/or P227 and particulate medicament |
| US5202110A (en) * | 1992-01-22 | 1993-04-13 | Virginia Commonwealth University | Formulations for delivery of beclomethasone diproprionate by metered dose inhalers containing no chlorofluorocarbon propellants |
| US5196575A (en) * | 1992-02-19 | 1993-03-23 | Hoechst Celanese Corp. | Supercritical separation of isomers of functional organic compounds at moderate conditions |
| US5314682A (en) * | 1992-09-21 | 1994-05-24 | Great Lakes Chemical Corp. | Ozone friendly sterilant mixture |
| ATE290864T1 (de) * | 1993-03-26 | 2005-04-15 | Franciscus Wilhelmus He Merkus | Pharmazeutische zusammensetzungen zur intranasalen verabreichung von dihydroergotamin |
| US5492688A (en) * | 1993-04-28 | 1996-02-20 | The Center For Innovative Technology | Metered dose inhaler fomulations which include the ozone-friendly propellant HFC 134a and a pharmaceutically acceptable suspending, solubilizing, wetting, emulsifying or lubricating agent |
| TW402506B (en) * | 1993-06-24 | 2000-08-21 | Astra Ab | Therapeutic preparation for inhalation |
| JP3750872B2 (ja) * | 1993-07-14 | 2006-03-01 | 株式会社小松製作所 | 車両用エンジンの過給装置およびその制御方法 |
| EP0728037B1 (en) * | 1993-11-08 | 1999-01-13 | The Gillette Company | Method of forming particles using a supercritical fluid, aerogel particles formed thereby, and antiperspirants containing aerogel particles |
| GB9404945D0 (en) * | 1994-03-15 | 1994-04-27 | Glaxo Group Ltd | Pharmaceutical composition |
| US5508023A (en) * | 1994-04-11 | 1996-04-16 | The Center For Innovative Technology | Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant |
| GB9413202D0 (en) * | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
| MX9504934A (es) * | 1994-12-12 | 1997-01-31 | Morton Int Inc | Revestimientos en polvo de pelicula delgada lisa. |
| US6013245A (en) * | 1995-01-26 | 2000-01-11 | Glaxo Group Limited | Aerosol formulation containing beclomethasone dipropionate and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant |
| US5639475A (en) * | 1995-02-03 | 1997-06-17 | Eurand America, Incorporated | Effervescent microcapsules |
| US5607697A (en) * | 1995-06-07 | 1997-03-04 | Cima Labs, Incorporated | Taste masking microparticles for oral dosage forms |
| GB9526392D0 (en) * | 1995-12-22 | 1996-02-21 | Glaxo Group Ltd | Medicaments |
| US5874029A (en) * | 1996-10-09 | 1999-02-23 | The University Of Kansas | Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent |
| US5875776A (en) * | 1996-04-09 | 1999-03-02 | Vivorx Pharmaceuticals, Inc. | Dry powder inhaler |
| US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| US6503480B1 (en) * | 1997-05-23 | 2003-01-07 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| US6054488A (en) * | 1996-06-11 | 2000-04-25 | 3M Innovative Properties Company | Medicinal aerosol formulations of formoterol |
| US6068832A (en) * | 1996-08-29 | 2000-05-30 | Schering Corporation | Chlorofluorocarbon-free mometasone furoate aerosol formulations |
| US5891885A (en) * | 1996-10-09 | 1999-04-06 | Algos Pharmaceutical Corporation | Method for treating migraine |
| US6077539A (en) * | 1996-11-12 | 2000-06-20 | Pozen, Inc. | Treatment of migraine headache |
| US6024981A (en) * | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
| US6200293B1 (en) * | 1997-08-27 | 2001-03-13 | Science Incorporated | Fluid delivery device with temperature controlled energy source |
| US5954047A (en) * | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
| GB9808802D0 (en) * | 1998-04-24 | 1998-06-24 | Glaxo Group Ltd | Pharmaceutical formulations |
| GB9810559D0 (en) * | 1998-05-15 | 1998-07-15 | Bradford Particle Design Ltd | Method and apparatus for particle formation |
| ES2234266T3 (es) * | 1998-07-24 | 2005-06-16 | Jago Research Ag | Formulaciones medicas para aerosoles. |
| US6387410B1 (en) * | 1998-09-10 | 2002-05-14 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
| IT1303788B1 (it) * | 1998-11-25 | 2001-02-23 | Chiesi Farma Spa | Formulazioni di aerosol medicinali. |
| US6119853A (en) * | 1998-12-18 | 2000-09-19 | Glaxo Wellcome Inc. | Method and package for storing a pressurized container containing a drug |
| US6390291B1 (en) * | 1998-12-18 | 2002-05-21 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
| US6395299B1 (en) * | 1999-02-12 | 2002-05-28 | Biostream, Inc. | Matrices for drug delivery and methods for making and using the same |
| US6395300B1 (en) * | 1999-05-27 | 2002-05-28 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| US6858199B1 (en) * | 2000-06-09 | 2005-02-22 | Advanced Inhalation Research, Inc. | High efficient delivery of a large therapeutic mass aerosol |
| WO2001038002A1 (en) * | 1999-09-13 | 2001-05-31 | Sheffield Pharmaceuticals, Inc. | Aerosol airflow control system and method |
| US6346323B1 (en) * | 1999-10-07 | 2002-02-12 | Sig Pack Systems Ag | Multi-layer synthetic film |
| US6367471B1 (en) * | 1999-11-01 | 2002-04-09 | Sheffield Pharmaceuticals, Inc. | Internal vortex mechanism for inhaler device |
| US6620351B2 (en) * | 2000-05-24 | 2003-09-16 | Auburn University | Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer |
| US6406681B1 (en) * | 2000-08-21 | 2002-06-18 | Aeropharm Technology, Inc. | Method of treating a systemic disease |
| US6514482B1 (en) * | 2000-09-19 | 2003-02-04 | Advanced Inhalation Research, Inc. | Pulmonary delivery in treating disorders of the central nervous system |
| JP2005503425A (ja) * | 2001-05-24 | 2005-02-03 | アレックザ モレキュラー デリヴァリー コーポレイション | 所定の吸入ルートによる薬剤エステルの送出 |
| US20030198669A1 (en) * | 2001-07-05 | 2003-10-23 | R.T. Alamo Ventures I, Llc | Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine |
| US6685951B2 (en) * | 2001-07-05 | 2004-02-03 | R. T. Alamo Ventures I, Inc. | Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine |
| GB0117696D0 (en) * | 2001-07-20 | 2001-09-12 | Bradford Particle Design Plc | Particle information |
| US20030091513A1 (en) * | 2001-10-03 | 2003-05-15 | Mohsen Nahed M. | Method to generate water soluble or nonwater soluble in nanoparticulates directly in suspension or dispersion media |
| US6560907B1 (en) * | 2002-01-18 | 2003-05-13 | Thomas Vieweg | Cartridge magazine system |
| US7582284B2 (en) * | 2002-04-17 | 2009-09-01 | Nektar Therapeutics | Particulate materials |
| US20060147389A1 (en) * | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
| JP2007505136A (ja) * | 2003-09-10 | 2007-03-08 | マツプ・フアーマシユーテイカルズ・インコーポレーテツド | ジヒドロエルゴタミンを肺吸入により体循環に送達するためのエアゾール製剤 |
| US9682043B2 (en) * | 2003-12-09 | 2017-06-20 | Medcrystalforms, Llc | Method of preparation of mixed phase co-crystals with active agents |
| WO2006039631A2 (en) * | 2004-09-30 | 2006-04-13 | Centocor, Inc. | Methods and compositions for treating renal cell carcinoma related pathologies |
| WO2008076287A2 (en) * | 2006-12-13 | 2008-06-26 | Tuel Stephen M | Methods of making pharmaceutical components for customized drug products |
| WO2008097664A1 (en) * | 2007-02-11 | 2008-08-14 | Map Pharmaceuticals, Inc. | Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile |
-
2004
- 2004-09-10 JP JP2006526324A patent/JP2007505136A/ja not_active Withdrawn
- 2004-09-10 CA CA002538237A patent/CA2538237A1/en not_active Abandoned
- 2004-09-10 US US10/572,012 patent/US20080118442A1/en not_active Abandoned
- 2004-09-10 AU AU2004272077A patent/AU2004272077A1/en not_active Abandoned
- 2004-09-10 WO PCT/US2004/029632 patent/WO2005025506A2/en not_active Ceased
- 2004-09-10 EP EP04783739A patent/EP1663159A4/en not_active Withdrawn
-
2006
- 2006-04-06 NO NO20061561A patent/NO20061561L/no not_active Application Discontinuation
-
2007
- 2007-03-13 US US11/717,276 patent/US20070253913A1/en not_active Abandoned
-
2010
- 2010-03-19 AU AU2010201070A patent/AU2010201070A1/en not_active Withdrawn
-
2012
- 2012-01-05 JP JP2012000374A patent/JP2012116841A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005025506A2 (en) | 2005-03-24 |
| AU2004272077A1 (en) | 2005-03-24 |
| WO2005025506A3 (en) | 2006-03-16 |
| JP2012116841A (ja) | 2012-06-21 |
| EP1663159A4 (en) | 2010-06-09 |
| AU2010201070A1 (en) | 2010-04-15 |
| US20070253913A1 (en) | 2007-11-01 |
| JP2007505136A (ja) | 2007-03-08 |
| EP1663159A2 (en) | 2006-06-07 |
| US20080118442A1 (en) | 2008-05-22 |
| CA2538237A1 (en) | 2005-03-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20061561L (no) | Aerosolformuleringer for avlevering av dihydroergotamin til den systemiske sirkulasjon via pulmonaer inhalering | |
| US10398673B2 (en) | Mast cell stabilizers treatment for systemic disorders | |
| Kumar et al. | Intranasal drug delivery: A non-invasive approach for the better delivery of neurotherapeutics | |
| YU36302A (sh) | Novi tiotropiumski preparati - koji sadrže prah za inhaliranje | |
| GEP20063876B (en) | Pressurised metered dose inhalers containing solutions of beta-2 agonists | |
| SG146649A1 (en) | Mucoactive agents for treating a pulmonary disease | |
| PE20030949A1 (es) | Formulaciones en aerosol para la administracion pulmonar de medicamentos que producen un efecto sistemico | |
| WO2005025535A3 (en) | Methods for preparing pharmaceutical compositions | |
| CN115427076B (zh) | 用于治疗冠状病毒感染的人去泛素化酶抑制剂 | |
| NO20064161L (no) | Farmasoytiske formuleringer for torrpulverinhalatorer omfattende en aktiv ingrediens med lavdoseringsstyrke | |
| CN102740912A (zh) | 一种用于产生细小的浓缩气溶胶的方法和设备 | |
| RU2005135332A (ru) | Назальные фармацевтические композиции и способы их применения | |
| MX2017004476A (es) | Composicion que comprende al menos un polvo seco obtenido por secado por atomizacion para aumentar la estabilidad de la formulacion. | |
| WO2005048985A3 (en) | Alpha 1-antitrypsin compositions and treatment methods using such compositions | |
| MX2020011474A (es) | Nuevo tratamiento de enfermedades pulmonares intersticiales. | |
| HRP20120286T1 (hr) | Kombinacija antikolinergika i inhibitora fosfodiesteraze tip 4 za liječenje respiratornih bolesti | |
| CN115515587A (zh) | 用于治疗冠状病毒感染的6’-甲氧基辛可宁-9-醇类 | |
| MX2020010977A (es) | Procedimientos de tratamiento de infecciones fúngicas. | |
| Lewis et al. | New actuators versus old: reasons and results for actuator modifications for HFA solution MDIs | |
| NO20053090L (no) | Pulverformulering for innhalering inneholdende tiotropium. | |
| Yang et al. | Excipient-free, spray-dried powders for pulmonary aztreonam delivery | |
| JP2016531138A5 (no) | ||
| JPH09227373A (ja) | 抗インフルエンザウイルス剤 | |
| CN111971034A (zh) | 一种含格隆铵盐的气雾剂药物组合物及其制备方法与应用 | |
| Xu et al. | A novel pullulan excipient for inhalable spray-dried powders |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |