NO20062300L - Fremgangsmater og reagenser for behandling av inflammatoriske forstyrelser - Google Patents

Fremgangsmater og reagenser for behandling av inflammatoriske forstyrelser

Info

Publication number
NO20062300L
NO20062300L NO20062300A NO20062300A NO20062300L NO 20062300 L NO20062300 L NO 20062300L NO 20062300 A NO20062300 A NO 20062300A NO 20062300 A NO20062300 A NO 20062300A NO 20062300 L NO20062300 L NO 20062300L
Authority
NO
Norway
Prior art keywords
treatment
reagents
methods
inflammatory disorders
compound
Prior art date
Application number
NO20062300A
Other languages
English (en)
Inventor
Edward Roydon Jost-Price
Brendan Smith
Benjamin A Auspitz
Palaniyandi Manivasakam
Michael S Slavonic
Original Assignee
Combinatorx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Combinatorx Inc filed Critical Combinatorx Inc
Publication of NO20062300L publication Critical patent/NO20062300L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Oppfinnelsen omfatter en fremgangsmåte for behandling av en immunoinflammatorisk administrering av en forbindelse med formel (1), f.eks. ibudilast eller KC-764, alene eller i kombinasjon med et kortikosteroid, tetrasubstituert pyrimidopyrimidin eller annen forbindelse. Oppfinnelsen angår også farmasøytiske blandinger omfattende kombinasjonen ovenfor for behandling eller forebygging av en immuninflammatorisk forstyrrelse.
NO20062300A 2003-11-21 2006-05-22 Fremgangsmater og reagenser for behandling av inflammatoriske forstyrelser NO20062300L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52411703P 2003-11-21 2003-11-21
PCT/US2004/038512 WO2005051293A2 (en) 2003-11-21 2004-11-17 Methods and reagents for the treatment of inflammatory disorders

Publications (1)

Publication Number Publication Date
NO20062300L true NO20062300L (no) 2006-08-21

Family

ID=34632866

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062300A NO20062300L (no) 2003-11-21 2006-05-22 Fremgangsmater og reagenser for behandling av inflammatoriske forstyrelser

Country Status (17)

Country Link
US (2) US7709495B2 (no)
EP (1) EP1689390B1 (no)
JP (1) JP2007512337A (no)
KR (1) KR20060120208A (no)
CN (1) CN1905870A (no)
AT (1) ATE497763T1 (no)
AU (1) AU2004292445B2 (no)
BR (1) BRPI0416812A (no)
CA (1) CA2546347A1 (no)
DE (1) DE602004031356D1 (no)
IL (1) IL175781A0 (no)
NO (1) NO20062300L (no)
NZ (1) NZ547389A (no)
RU (1) RU2006121978A (no)
SG (1) SG148198A1 (no)
WO (1) WO2005051293A2 (no)
ZA (1) ZA200604253B (no)

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JP2007512337A (ja) * 2003-11-21 2007-05-17 コンビナトアールエックス インコーポレーティッド 炎症性障害の治療のための方法および試薬
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EP2026804A1 (en) * 2006-05-31 2009-02-25 Avigen, Inc. Ibudilast for inhibiting macrophage migration inhibitory factor (mif) activity
JP5352452B2 (ja) * 2006-06-06 2013-11-27 メディシノバ, インコーポレイテッド 置換ピラゾロ[1,5−a]ピリジン化合物およびその使用方法
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GB201305714D0 (en) 2013-03-28 2013-05-15 Ucl Business Plc Method
RU2536274C1 (ru) * 2013-12-20 2014-12-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Тверская государственная медицинская академия" Министерства здравоохранения Российской Федерации Способ лечения бородавок
CN108033959A (zh) * 2018-01-29 2018-05-15 山东省药学科学院 一种异丁司特的化学合成方法
WO2019226515A1 (en) * 2018-05-21 2019-11-28 The University Of North Carolina At Chapel Hill Methods of inhibiting proinflammatory neuroimmune signaling and treating inflammatory disorders
CN113456618A (zh) * 2020-03-31 2021-10-01 天津金耀集团有限公司 一种复方双嘧达莫的吸入制剂及其制备方法
CN115335049A (zh) * 2020-04-06 2022-11-11 美迪诺亚公司 降低患者中巨噬细胞迁移抑制因子的血浆水平的方法
CN116887829A (zh) * 2021-01-29 2023-10-13 美迪诺亚公司 治疗化学气体暴露的方法
KR20240019682A (ko) * 2022-08-04 2024-02-14 국민대학교산학협력단 디카르복실산 또는 이의 유도체를 포함하는 장내 미생물 균총 개선용 조성물
CN115414354A (zh) * 2022-08-29 2022-12-02 西南医科大学 花椒毒素在制备治疗血小板减少症药物中的应用
KR102900597B1 (ko) * 2022-12-09 2025-12-18 대한민국 Impdh 억제제를 포함하는 중증열성혈소판감소증후군 예방 또는 치료용 조성물

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Also Published As

Publication number Publication date
SG148198A1 (en) 2008-12-31
AU2004292445B2 (en) 2010-02-04
WO2005051293A3 (en) 2006-03-02
WO2005051293A2 (en) 2005-06-09
US20100210606A1 (en) 2010-08-19
CA2546347A1 (en) 2005-06-09
ZA200604253B (en) 2007-10-31
ATE497763T1 (de) 2011-02-15
NZ547389A (en) 2009-11-27
US7709495B2 (en) 2010-05-04
IL175781A0 (en) 2008-04-13
EP1689390A2 (en) 2006-08-16
CN1905870A (zh) 2007-01-31
EP1689390B1 (en) 2011-02-09
DE602004031356D1 (de) 2011-03-24
KR20060120208A (ko) 2006-11-24
BRPI0416812A (pt) 2007-03-06
RU2006121978A (ru) 2007-12-27
EP1689390A4 (en) 2008-03-12
US20050187203A1 (en) 2005-08-25
AU2004292445A1 (en) 2005-06-09
JP2007512337A (ja) 2007-05-17

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