NO20062563L - Nye 5,6-Dihydropyrin-2-on forbindelser anvendelige som inhibitorer av trombin - Google Patents

Nye 5,6-Dihydropyrin-2-on forbindelser anvendelige som inhibitorer av trombin

Info

Publication number
NO20062563L
NO20062563L NO20062563A NO20062563A NO20062563L NO 20062563 L NO20062563 L NO 20062563L NO 20062563 A NO20062563 A NO 20062563A NO 20062563 A NO20062563 A NO 20062563A NO 20062563 L NO20062563 L NO 20062563L
Authority
NO
Norway
Prior art keywords
thrombin
inhibitors
dihydropyrin
new
compounds useful
Prior art date
Application number
NO20062563A
Other languages
English (en)
Norwegian (no)
Inventor
Tord Inghardt
David Gustafsson
Mats Nagard
Kristina Berggren
Ojvind Davidsson
Ola Fjellstrom
Ingemar Nilsson
Eric Therrien
Otterlo Willem Van
Stephen Hanessian
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0303452A external-priority patent/SE0303452D0/xx
Priority claimed from SE0401344A external-priority patent/SE0401344D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20062563L publication Critical patent/NO20062563L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/98—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
NO20062563A 2003-12-18 2006-06-02 Nye 5,6-Dihydropyrin-2-on forbindelser anvendelige som inhibitorer av trombin NO20062563L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0303452A SE0303452D0 (sv) 2003-12-18 2003-12-18 New compounds
SE0401344A SE0401344D0 (sv) 2004-05-25 2004-05-25 New compounds
PCT/SE2004/001878 WO2005058826A1 (en) 2003-12-18 2004-12-15 New 5,6-dihydropyrin-2-one compounds useful as inhibitors of thrombin

Publications (1)

Publication Number Publication Date
NO20062563L true NO20062563L (no) 2006-06-29

Family

ID=34703498

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062563A NO20062563L (no) 2003-12-18 2006-06-02 Nye 5,6-Dihydropyrin-2-on forbindelser anvendelige som inhibitorer av trombin

Country Status (15)

Country Link
US (1) US20070099962A1 (pt)
EP (1) EP1697323A1 (pt)
JP (1) JP2007514742A (pt)
AR (1) AR047408A1 (pt)
AU (1) AU2004299433A1 (pt)
BR (1) BRPI0417635A (pt)
CA (1) CA2547064A1 (pt)
IL (1) IL175791A0 (pt)
MX (1) MXPA06006927A (pt)
NO (1) NO20062563L (pt)
RU (1) RU2335492C2 (pt)
SA (1) SA04250414B1 (pt)
TW (1) TW200530216A (pt)
UY (1) UY28675A1 (pt)
WO (1) WO2005058826A1 (pt)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4427979A1 (de) * 1993-11-15 1996-02-15 Cassella Ag Substituierte 5-Ring-Heterocyclen, ihre Herstellung und ihre Verwendung
US5932733A (en) * 1994-06-17 1999-08-03 Corvas International, Inc. 3-amino-2-oxo-1-piperidineacetic derivatives containing an arginine mimic as enzyme inhibitors
US5668289A (en) * 1996-06-24 1997-09-16 Merck & Co., Inc. Pyridinone thrombin inhibitors
US5792779A (en) * 1997-02-19 1998-08-11 Merck & Co., Inc. Pyridinone thrombin inhibitors
US5866573A (en) * 1997-04-21 1999-02-02 Merck & Co., Inc. Pyrazinone thrombin inhibitors
PL336589A1 (en) * 1997-05-02 2000-07-03 Akzo Nobel Nv Serinic protease inhibitors
AU2002246675A1 (en) * 2000-12-18 2002-07-30 Merck And Co., Inc. Thrombin inhibitors
SI21097A (sl) * 2001-12-04 2003-06-30 Univerza V Ljubljani Inhibitorji trombina
AR047521A1 (es) * 2004-02-06 2006-01-25 Astrazeneca Ab Compuestos piridin-2-ona utiles como inhibidores de trombina

Also Published As

Publication number Publication date
US20070099962A1 (en) 2007-05-03
JP2007514742A (ja) 2007-06-07
WO2005058826A8 (en) 2005-10-27
EP1697323A1 (en) 2006-09-06
AR047408A1 (es) 2006-01-18
RU2006123361A (ru) 2008-01-27
WO2005058826A1 (en) 2005-06-30
UY28675A1 (es) 2005-07-29
AU2004299433A1 (en) 2005-06-30
TW200530216A (en) 2005-09-16
BRPI0417635A (pt) 2007-03-27
SA04250414B1 (ar) 2007-07-31
MXPA06006927A (es) 2006-08-23
CA2547064A1 (en) 2005-06-30
RU2335492C2 (ru) 2008-10-10
IL175791A0 (en) 2006-10-05

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application