NO20062877L - Stabile liposomsammensetninger som omfatter lipofile aminholdige farmasoytiske midler - Google Patents

Stabile liposomsammensetninger som omfatter lipofile aminholdige farmasoytiske midler

Info

Publication number
NO20062877L
NO20062877L NO20062877A NO20062877A NO20062877L NO 20062877 L NO20062877 L NO 20062877L NO 20062877 A NO20062877 A NO 20062877A NO 20062877 A NO20062877 A NO 20062877A NO 20062877 L NO20062877 L NO 20062877L
Authority
NO
Norway
Prior art keywords
pharmaceutically acceptable
lipophilic amine
compositions
composition
methods
Prior art date
Application number
NO20062877A
Other languages
English (en)
Inventor
Blagoja Ristevski
James Charles Boylan
Hong Li
Diana Helen Pliura
Original Assignee
Delex Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delex Therapeutics Inc filed Critical Delex Therapeutics Inc
Publication of NO20062877L publication Critical patent/NO20062877L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Stabil liposomsammensetning for levering av et farmasøytisk middel, hvor sammensetningen omfatter: (a) et egnet vandig medium, (b) liposomer dannet av et egnet fosfolipid; (c) minst ett farmasøytisk middel som i det minste delvis er innkapslet i liposomene, og er valgt fra (i) et lipofilt amin og en farmasøytisk akseptabel syre, hvor den farmasøytisk akseptable syren er valgt fra en organisk eller uorganisk syre, og (ii) et farmasøytisk akseptabelt organisk syresalt av et lipofilt amin, og eventuelt en farmasøytisk akseptabel organisk syre; hvor mengden av den farmasøytisk akseptable syren som er tilstede i sammensetningen, er slik at liposomsammensetningens pH-verdi er mindre enn eller omtrent lik pKa-verdien for aminogruppen i det farmasøytisk aktive lipofile aminet. Det er også tilveiebrakt sammensetninger, sett og fremgangsmåter for fremstilling av samme, så vel som fremgangsmåter for ytterligere å bedre stabiliteten på sammensetningene ved autoklavering, foruten fremgangsmåter for å identifisere stabile liposomsammensetninger ifølge den foreliggende oppfinnelsen.
NO20062877A 2003-11-20 2006-06-19 Stabile liposomsammensetninger som omfatter lipofile aminholdige farmasoytiske midler NO20062877L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52331603P 2003-11-20 2003-11-20
PCT/CA2004/002002 WO2005048986A1 (en) 2003-11-20 2004-11-22 Stable liposome compositions comprising lipophilic amine containing pharmaceutical agents

Publications (1)

Publication Number Publication Date
NO20062877L true NO20062877L (no) 2006-08-21

Family

ID=34619598

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062877A NO20062877L (no) 2003-11-20 2006-06-19 Stabile liposomsammensetninger som omfatter lipofile aminholdige farmasoytiske midler

Country Status (13)

Country Link
US (1) US20070269502A1 (no)
EP (1) EP1689364A4 (no)
JP (1) JP2007511545A (no)
KR (1) KR20060123341A (no)
CN (2) CN1893926B (no)
AU (1) AU2004290476A1 (no)
BR (1) BRPI0416650A (no)
CA (1) CA2588012A1 (no)
MX (1) MXPA06005688A (no)
NO (1) NO20062877L (no)
RU (1) RU2369384C2 (no)
WO (1) WO2005048986A1 (no)
ZA (1) ZA200604808B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4599849B2 (ja) * 2004-02-18 2010-12-15 コニカミノルタエムジー株式会社 リポソーム含有製剤の製造方法、およびリポソーム含有製剤
US8772359B2 (en) 2006-11-08 2014-07-08 Cp Kelco U.S., Inc. Surfactant thickened systems comprising microfibrous cellulose and methods of making same
US9045716B2 (en) 2006-11-08 2015-06-02 Cp Kelco U.S., Inc. Surfactant thickened systems comprising microfibrous cellulose and methods of making same
WO2009107753A1 (ja) 2008-02-29 2009-09-03 財団法人 名古屋産業科学研究所 後眼部到達用リポソーム及び後眼部疾患用医薬組成物
US9445975B2 (en) 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
CH702736B1 (de) * 2008-12-31 2012-12-14 Obschestvo S Organichennoi Otvetstvennostju Scient Company Flamena Phospholipid-Emulsion, die Dihydroquerzetin beinhaltet.
EP2585046A4 (en) * 2010-06-23 2013-11-06 Brightside Innovations Inc LECITHINTRÄGERVESIKEL AND METHOD FOR THE PRODUCTION THEREOF
EP2771341A4 (en) * 2011-10-28 2015-09-23 Univ Texas NEW COMPOSITIONS AND METHOD FOR THE TREATMENT OF CANCER
JP2015507019A (ja) * 2012-02-17 2015-03-05 セルシオン コーポレイション 感熱性ナノ粒子製剤およびその製造方法
JPWO2014017233A1 (ja) * 2012-07-27 2016-07-07 住友重機械工業株式会社 微生物用活性調節剤及び微生物の活性を調節する方法
RU2529179C1 (ru) * 2013-04-23 2014-09-27 Общество с ограниченной ответственностью "Уральский центр биофармацевтических технологий" Стабилизатор липосомальных суспензий и способ его получения
AU2016256979B2 (en) 2015-05-04 2021-01-28 Genfit Method for preparing transmembrane pH-gradient vesicles
EP3416636A4 (en) * 2016-02-15 2019-10-16 Kemin Industries, Inc. WATER-SOLUBLE LIPOPHILIC SUBSTANCES
WO2019126766A1 (en) * 2017-12-21 2019-06-27 Taiwan Liposome Co., Ltd. Sustained-release triptan compositions and method of use the same through subdermal route or the like
EP3991722A4 (en) * 2019-06-28 2022-10-05 Jiangsu Hengrui Medicine Co., Ltd. LIPID COMPOSITION WITH DELAYED RELEASE AND THEIR PROCESS OF PRODUCTION
CN112823009A (zh) * 2019-08-28 2021-05-18 上海谷森医药有限公司 糠酸氟替卡松脂质体制剂及其制备方法
RU2712079C1 (ru) * 2019-09-05 2020-01-24 Федеральное государственное бюджетное учреждение науки "Уральский научно-практический центр радиационной медицины Федерального медико-биологического агентства" (ФГБУН УНПЦ РМ ФМБА России) Липосомальное лекарственное средство для лечения местных радиационных поражений кожи
CN113197848B (zh) * 2021-05-24 2023-06-09 成都欣捷高新技术开发股份有限公司 一种重酒石酸间羟胺药物组合物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0152379A3 (de) * 1984-02-15 1986-10-29 Ciba-Geigy Ag Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen
AU598958B2 (en) * 1987-11-12 1990-07-05 Vestar, Inc. Improved amphotericin b liposome preparation
WO1990003808A1 (en) * 1988-10-07 1990-04-19 The Liposome Company, Inc. Heat treating liposomes
WO1990014105A1 (en) * 1989-05-15 1990-11-29 The Liposome Company, Inc. Accumulation of drugs into liposomes by a proton gradient
JP3383704B2 (ja) * 1993-04-02 2003-03-04 わかもと製薬株式会社 安定なリポソーム水分散液
US5451408A (en) * 1994-03-23 1995-09-19 Liposome Pain Management, Ltd. Pain management with liposome-encapsulated analgesic drugs
GB9605915D0 (en) * 1996-03-21 1996-05-22 Univ Bruxelles Liposome encapsulated amphiphilic drug compositions
GB9708066D0 (en) * 1997-04-22 1997-06-11 Woolcombers Group Plc Compositions and their use
WO2003075889A1 (en) * 2002-03-05 2003-09-18 Transave, Inc. An inhalation system for prevention and treatment of intracellular infections

Also Published As

Publication number Publication date
ZA200604808B (en) 2007-11-28
RU2369384C2 (ru) 2009-10-10
RU2006121554A (ru) 2007-12-27
AU2004290476A1 (en) 2005-06-02
CN101889981A (zh) 2010-11-24
EP1689364A1 (en) 2006-08-16
CN1893926B (zh) 2010-09-08
EP1689364A4 (en) 2008-10-29
MXPA06005688A (es) 2006-12-14
US20070269502A1 (en) 2007-11-22
CN1893926A (zh) 2007-01-10
BRPI0416650A (pt) 2007-01-16
WO2005048986A1 (en) 2005-06-02
CA2588012A1 (en) 2005-06-02
KR20060123341A (ko) 2006-12-01
JP2007511545A (ja) 2007-05-10

Similar Documents

Publication Publication Date Title
NO20062877L (no) Stabile liposomsammensetninger som omfatter lipofile aminholdige farmasoytiske midler
BRPI0509795A (pt) composto ou um sal farmacologicamente aceitável do mesmo, composição farmacêutica, uso do composto ou sal farmacologicamente aceitável do mesmo, e, método para promover osteogênese, supressão de ressorção óssea e/ou melhoramento da densidade óssea
ATE409461T1 (de) Hfc lösungsformulierungen enthaltend ein anticholinergikum
BR0211284A (pt) Derivados de 1-fenilsulfonil-1,3-dihidro-2h-indol-2-ona, a respectiva preparação e a respectiva aplicação em terapêutica
DE50109317D1 (de) Desinfektionsmittel
NO20052496L (no) Selekterte CGRP antagonister, fremgangsmater for fremstilling derav og anvendelse derav som medikamenter.
NO20072478L (no) Salter av isofosforamidsennep og analoger av disse som antitumor midler
BRPI0508579A (pt) composto, composição farmacêutica, e, uso de um composto
NO20072515L (no) 2-amido-4-fenyltnazolderivater, fremstilling og terapeutsik anvendelse derav
AR082049A1 (es) Formulaciones liquidas de rupatadina fumarato
ATE422356T1 (de) Pharmazeutische zubereitungen
RU2004119056A (ru) Составленные на основе воды фармацевтические композиции водорастворимых пролекарств пропофола
NO20073549L (no) Fremgangsmate for fremstilling av organiske forbindelser
CN102014618A (zh) 微乳剂型杀菌组合物
NO20062401L (no) Anvendelse av et hydroksimsyrehalidderivat i behandling av neurodegenerative sykdommer
MA27670A1 (fr) Composition pharmaceutique contenant de l'acide 5-methyl-2-2'-(chloro-6'-fluoroanilino)phenylacetique
CA2364864A1 (fr) Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions phamaceutiques qui les contiennent
PE20030092A1 (es) Formulacion de una solucion de inhalacion con una sal de tiotropio
MEP40708A (en) Inhalative solution formulation containing a tiotropium salt
UA93529C2 (ru) Соли и смеси 9-оксоакридин-10-уксусной кислоты c 1-алкиламино-1-дезоксиполиолами
PE20060484A1 (es) Preparaciones farmaceuticas liquidas que comprenden un compuesto de benzhidril piperizina
DE602004001393D1 (de) Stabile pharmazeutische zusammensetzung mit safingol und verfahren zu dessen verwendung
BR0002076A (pt) Compostos 1-aza-2-alquil-6-aril-cicloalcano, um processo para sua preparação e composições farmacêuticas contendo estes
NO20055311L (no) Farmasoytisk aktive ornitinderivater, ammoniumsalter derav og fremgangsmater for fremstilling av det samme
NO20090741L (no) Imino-imidazo-pyridinderivater med antitrombotisk aktivitet

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application