NO20063859L - Cykloalkylsubstituerte 7-amino-4-kinolon-3-karboksylsyrederivater, fremgangsmate for fremstilling derav og anvendelse derav som medikamenter - Google Patents
Cykloalkylsubstituerte 7-amino-4-kinolon-3-karboksylsyrederivater, fremgangsmate for fremstilling derav og anvendelse derav som medikamenterInfo
- Publication number
- NO20063859L NO20063859L NO20063859A NO20063859A NO20063859L NO 20063859 L NO20063859 L NO 20063859L NO 20063859 A NO20063859 A NO 20063859A NO 20063859 A NO20063859 A NO 20063859A NO 20063859 L NO20063859 L NO 20063859L
- Authority
- NO
- Norway
- Prior art keywords
- quinolone
- medicaments
- amino
- carboxylic acid
- acid derivatives
- Prior art date
Links
- CVSYGPGKZKCLHQ-UHFFFAOYSA-N 7-amino-4-oxo-3h-quinoline-3-carboxylic acid Chemical class O=C1C(C(O)=O)C=NC2=CC(N)=CC=C21 CVSYGPGKZKCLHQ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Det er beskrevet cykloalkylsubstituerte 7-amino-4-quinolon-3-karboksylsyrederivater samt deres fysiologisk godtakbare salter og fysiologisk funksjonelle derivater. Oppfinnelsen vedrører forbindelsene med formel (I), hvori resten har de angitte betydningene, samt deres fysiologisk godtakbare salter. Forbindelsene egner seg f.eks. som medikamenter for forebyggelse og behandling av diabetes type 2.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004004971A DE102004004971B3 (de) | 2004-01-31 | 2004-01-31 | Cycloalkyl substituierte 7-Amino-4-chinolon-3-carbonsäure-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arnzeimittel |
| PCT/EP2005/000373 WO2005073231A1 (de) | 2004-01-31 | 2005-01-15 | Cycloalkyl substituierte 7-amino-4-chinolon-3-carbonsäure-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20063859L true NO20063859L (no) | 2006-08-29 |
Family
ID=34813070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20063859A NO20063859L (no) | 2004-01-31 | 2006-08-29 | Cykloalkylsubstituerte 7-amino-4-kinolon-3-karboksylsyrederivater, fremgangsmate for fremstilling derav og anvendelse derav som medikamenter |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1713804B1 (no) |
| JP (1) | JP4838730B2 (no) |
| KR (1) | KR20060132672A (no) |
| CN (1) | CN1910182A (no) |
| AT (1) | ATE389654T1 (no) |
| AU (1) | AU2005209368A1 (no) |
| BR (1) | BRPI0507321A (no) |
| CA (1) | CA2554527A1 (no) |
| DE (2) | DE102004004971B3 (no) |
| IL (1) | IL176915A0 (no) |
| MA (1) | MA28340A1 (no) |
| MX (1) | MXPA06007954A (no) |
| NO (1) | NO20063859L (no) |
| RU (1) | RU2006131307A (no) |
| WO (1) | WO2005073231A1 (no) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| US10954231B2 (en) | 2006-10-16 | 2021-03-23 | Bionomics Limited | Anxiolytic compounds |
| NZ576036A (en) | 2006-10-16 | 2010-10-29 | Bionomics Ltd | Naphthyridine containing compounds for treating anxiety disorders |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US9023848B2 (en) | 2011-03-02 | 2015-05-05 | Bionomics Limited | Small-molecules as therapeutics |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120058A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8895547B2 (en) | 2011-03-08 | 2014-11-25 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
| EP2707367B1 (en) | 2011-05-12 | 2019-10-09 | Bionomics Limited | Methods for preparing naphthyridines |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT841929E (pt) * | 1995-08-02 | 2003-09-30 | Darwin Discovery Ltd | Quinolonas e sua utilizacao terapeutica |
| GB0205165D0 (en) * | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| DK1503759T3 (da) * | 2002-05-14 | 2009-04-14 | Univ California | Substituerede quinoloncarboxylsyrer, deres derivater, virkningssted og anvendelser heraf |
-
2004
- 2004-01-31 DE DE102004004971A patent/DE102004004971B3/de not_active Expired - Fee Related
-
2005
- 2005-01-15 KR KR1020067015358A patent/KR20060132672A/ko not_active Withdrawn
- 2005-01-15 RU RU2006131307/04A patent/RU2006131307A/ru not_active Application Discontinuation
- 2005-01-15 DE DE502005003310T patent/DE502005003310D1/de not_active Expired - Lifetime
- 2005-01-15 CA CA002554527A patent/CA2554527A1/en not_active Abandoned
- 2005-01-15 WO PCT/EP2005/000373 patent/WO2005073231A1/de not_active Ceased
- 2005-01-15 MX MXPA06007954A patent/MXPA06007954A/es not_active Application Discontinuation
- 2005-01-15 JP JP2006549992A patent/JP4838730B2/ja not_active Expired - Fee Related
- 2005-01-15 AU AU2005209368A patent/AU2005209368A1/en not_active Abandoned
- 2005-01-15 BR BRPI0507321-9A patent/BRPI0507321A/pt not_active Application Discontinuation
- 2005-01-15 CN CNA2005800028932A patent/CN1910182A/zh active Pending
- 2005-01-15 EP EP05700960A patent/EP1713804B1/de not_active Expired - Lifetime
- 2005-01-15 AT AT05700960T patent/ATE389654T1/de not_active IP Right Cessation
-
2006
- 2006-07-17 IL IL176915A patent/IL176915A0/en unknown
- 2006-07-28 MA MA29219A patent/MA28340A1/fr unknown
- 2006-08-29 NO NO20063859A patent/NO20063859L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0507321A (pt) | 2007-06-26 |
| RU2006131307A (ru) | 2008-03-10 |
| JP4838730B2 (ja) | 2011-12-14 |
| DE502005003310D1 (de) | 2008-04-30 |
| IL176915A0 (en) | 2006-12-10 |
| EP1713804B1 (de) | 2008-03-19 |
| MA28340A1 (fr) | 2006-12-01 |
| WO2005073231A1 (de) | 2005-08-11 |
| DE102004004971B3 (de) | 2005-09-15 |
| ATE389654T1 (de) | 2008-04-15 |
| EP1713804A1 (de) | 2006-10-25 |
| MXPA06007954A (es) | 2007-03-21 |
| CA2554527A1 (en) | 2005-08-11 |
| AU2005209368A1 (en) | 2005-08-11 |
| JP2007519651A (ja) | 2007-07-19 |
| CN1910182A (zh) | 2007-02-07 |
| KR20060132672A (ko) | 2006-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |