NO20063942L - Saltformer av 4(-4-metylpiperazin-1-ylmetyl)-n-[4-metyl-3-(4-piperidin-3-yl)pyrimidin-2-ylamino)fenyl]-benzamid - Google Patents

Saltformer av 4(-4-metylpiperazin-1-ylmetyl)-n-[4-metyl-3-(4-piperidin-3-yl)pyrimidin-2-ylamino)fenyl]-benzamid

Info

Publication number: NO20063942L
Authority: NO; Norway
Prior art keywords: salt; methyl; benzamide; phenyl; tartrate
Prior art date: 2004-02-04

Application number

NO20063942A

Other languages

English (en)

Norwegian (no)

Inventor

Paul William Manley

Hans Michael Buerger

Michael Mutz

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-04

Filing date

2006-09-04

Publication date

2006-11-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34837520&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20063942(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-09-04 Application filed by Novartis Ag filed Critical Novartis Ag

2006-11-02 Publication of NO20063942L publication Critical patent/NO20063942L/no

Links

150000003839 salts Chemical group 0.000 title abstract 4
KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 title 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 abstract 1
FEWJPZIEWOKRBE-LWMBPPNESA-L D-tartrate(2-) Chemical class [O-]C(=O)[C@@H](O)[C@H](O)C([O-])=O FEWJPZIEWOKRBE-LWMBPPNESA-L 0.000 abstract 1
VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical class OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 1
FEWJPZIEWOKRBE-JCYAYHJZSA-L L-tartrate(2-) Chemical class [O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O FEWJPZIEWOKRBE-JCYAYHJZSA-L 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical class OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 abstract 1
125000003289 ascorbyl group Chemical class [H]O[C@@]([H])(C([H])([H])O*)[C@@]1([H])OC(=O)C(O*)=C1O* 0.000 abstract 1
SRSXLGNVWSONIS-UHFFFAOYSA-N benzenesulfonic acid Chemical class OS(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-N 0.000 abstract 1
150000001558 benzoic acid derivatives Chemical class 0.000 abstract 1
150000001860 citric acid derivatives Chemical class 0.000 abstract 1
CCZOANFFMASREE-UHFFFAOYSA-N cyclohexane;sulfamic acid Chemical compound NS(O)(=O)=O.C1CCCCC1 CCZOANFFMASREE-UHFFFAOYSA-N 0.000 abstract 1
JFCQEDHGNNZCLN-UHFFFAOYSA-N glutaric acid Chemical class OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 abstract 1
KTUFNOKKBVMGRW-UHFFFAOYSA-N imatinib Chemical class C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3N=C(C=CN=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 KTUFNOKKBVMGRW-UHFFFAOYSA-N 0.000 abstract 1
150000003893 lactate salts Chemical class 0.000 abstract 1
150000004701 malic acid derivatives Chemical class 0.000 abstract 1
150000002690 malonic acid derivatives Chemical class 0.000 abstract 1
IWYDHOAUDWTVEP-UHFFFAOYSA-M mandelate Chemical class [O-]C(=O)C(O)C1=CC=CC=C1 IWYDHOAUDWTVEP-UHFFFAOYSA-M 0.000 abstract 1
XTEGVFVZDVNBPF-UHFFFAOYSA-N naphthalene-1,5-disulfonic acid Chemical class C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1S(O)(=O)=O XTEGVFVZDVNBPF-UHFFFAOYSA-N 0.000 abstract 1
150000004727 oxaloacetic acid derivatives Chemical class 0.000 abstract 1
150000003873 salicylate salts Chemical class 0.000 abstract 1
PWEBUXCTKOWPCW-UHFFFAOYSA-L squarate Chemical class [O-]C1=C([O-])C(=O)C1=O PWEBUXCTKOWPCW-UHFFFAOYSA-L 0.000 abstract 1
150000003890 succinate salts Chemical class 0.000 abstract 1
150000003892 tartrate salts Chemical class 0.000 abstract 1
WKOLLVMJNQIZCI-UHFFFAOYSA-M vanillate Chemical class COC1=CC(C([O-])=O)=CC=C1O WKOLLVMJNQIZCI-UHFFFAOYSA-M 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Oncology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)

NO20063942A 2004-02-04 2006-09-04 Saltformer av 4(-4-metylpiperazin-1-ylmetyl)-n-[4-metyl-3-(4-piperidin-3-yl)pyrimidin-2-ylamino)fenyl]-benzamid NO20063942L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US54181704P	2004-02-04	2004-02-04
PCT/EP2005/001077 WO2005075454A2 (en)	2004-02-04	2005-02-03	SALT FORMS OF 4-(4-METHYLPIPERAZIN-1-YLMETHYL)-n-[4-METHYL-3-(4-PYRIDIN-3-YL)PYRIMIDIN-2-YLAMINO)PHENYL]-BENZAMIDE

Publications (1)

Publication Number	Publication Date
NO20063942L true NO20063942L (no)	2006-11-02

Family

ID=34837520

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20063942A NO20063942L (no)	2004-02-04	2006-09-04	Saltformer av 4(-4-metylpiperazin-1-ylmetyl)-n-[4-metyl-3-(4-piperidin-3-yl)pyrimidin-2-ylamino)fenyl]-benzamid

Country Status (22)

Country	Link
US (3)	US20080249104A1 (pt)
EP (1)	EP1713792B1 (pt)
JP (1)	JP4937760B2 (pt)
KR (2)	KR20060135735A (pt)
CN (1)	CN100558723C (pt)
AR (1)	AR047530A1 (pt)
AU (1)	AU2005211514B2 (pt)
BR (1)	BRPI0507464A (pt)
CA (1)	CA2553887C (pt)
EC (1)	ECSP066752A (pt)
IL (1)	IL177005A (pt)
MA (1)	MA28428B1 (pt)
MY (1)	MY144177A (pt)
NO (1)	NO20063942L (pt)
NZ (1)	NZ548714A (pt)
PE (1)	PE20051096A1 (pt)
PH (1)	PH12013500157A1 (pt)
RU (1)	RU2375355C2 (pt)
TN (1)	TNSN06243A1 (pt)
TW (1)	TWI347186B (pt)
WO (1)	WO2005075454A2 (pt)
ZA (1)	ZA200605972B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060235006A1 (en) *	2005-04-13	2006-10-19	Lee Francis Y	Combinations, methods and compositions for treating cancer
GT200600316A (es) *	2005-07-20	2007-04-02		Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida.
JP5844508B2 (ja)	2005-11-25	2016-01-20	ノバルティスアーゲー	メシル酸イマチニブのｆ結晶形
KR100799821B1 (ko) *	2007-02-05	2008-01-31	동화약품공업주식회사	신규한 이마티닙 캠실레이트 및 그의 제조방법
US7550591B2 (en)	2007-05-02	2009-06-23	Chemagis Ltd.	Imatinib production process
WO2008136010A1 (en) *	2007-05-07	2008-11-13	Natco Pharma Limited	A process for the preparation of highly pure imatinib base
WO2009036753A2 (de) *	2007-09-20	2009-03-26	Schebo Biotech Ag	Neue pharmazeutika, verfahren zu ihrer herstellung und ihre verwendung in der medizinischen therapie
EP2081556A1 (en)	2007-09-25	2009-07-29	Teva Pharmaceutical Industries Ltd.	Stable imatinib compositions
EP2062885A1 (en) *	2007-11-21	2009-05-27	Eczacibasi-Zentiva Kimyasal Ürünler Sanayi ve Ticaret A.S.	Acid addition salts of imatinib and formulations comprising the same
NZ779754A (en)	2009-01-16	2023-04-28	Exelixis Inc	Malate salt of n-(4-{ [6,7-bis(methyloxy)quinolin-4-yl] oxy} phenyl)-n’-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer
US20100189790A1 (en)	2009-01-23	2010-07-29	Teva Pharmaceutical Industries, Ltd.	Delayed release rasagiline formulation
US20100330130A1 (en) *	2009-05-22	2010-12-30	Actavis Group Ptc Ehf	Substantially pure imatinib or a pharmaceutically acceptable salt thereof
US8431576B2 (en)	2009-06-25	2013-04-30	Alkermes Pharma Ireland Limited	Heterocyclic compounds for the treatment of neurological and psychological disorders
US8933037B2 (en)	2009-09-28	2015-01-13	Medizinische Universitat Wien	Methods involving PDGFRBETA inhibitors
PL389357A1 (pl)	2009-10-22	2011-04-26	Tomasz Koźluk	Sole imatinibu z pochodnymi kwasów winowych i sposób ich wytwarzania
KR101138840B1 (ko) *	2009-12-28	2012-05-10	주식회사 셀트리온화학연구소	이마티닙 다이클로로아세트산염 및 이를 포함하는 항암제 조성물
KR20130055576A (ko)	2010-03-15	2013-05-28	낫코 파마 리미티드	고순도의 결정질 이마티닙 염기를 제조하는 방법
EA024088B1 (ru)	2010-06-18	2016-08-31	КРКА, д.д., НОВО МЕСТО	α-ФОРМА МЕЗИЛАТА ИМАТИНИБА, СПОСОБЫ ЕЕ ПОЛУЧЕНИЯ И СОДЕРЖАЩАЯ ЕЁ ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ
WO2012090221A1 (en)	2010-12-29	2012-07-05	Cadila Healthcare Limited	Novel salts of imatinib
EP2833866B2 (en)	2012-04-04	2024-11-27	Intervet International B.V.	Soft chewable pharmaceutical products
WO2014016848A2 (en)	2012-07-24	2014-01-30	Laurus Labs Private Limited	Solid forms of tyrosine kinase inhibitors, process for the preparation and their pharmaceutical composition thereof
EP3782604A1 (en)	2013-07-31	2021-02-24	Windward Pharma, Inc.	Aerosol tyrosine kinase inhibitor compounds and uses thereof
SI3407874T1 (sl)	2016-01-25	2024-10-30	Krka, D.D., Novo Mesto	Hitro disperzibilni farmacevtski sestavek, ki obsega zaviralca tirozin-kinaze
EP3761983A1 (en)	2018-03-05	2021-01-13	Alkermes Pharma Ireland Limited	Aripiprazole dosing strategy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW225528B (pt) *	1992-04-03	1994-06-21	Ciba Geigy Ag
US5521184A (en) *	1992-04-03	1996-05-28	Ciba-Geigy Corporation	Pyrimidine derivatives and processes for the preparation thereof
JP3691861B2 (ja) *	1994-09-14	2005-09-07	株式会社東芝	光ディスク用光パルス幅制御装置
CO4940418A1 (es) *	1997-07-18	2000-07-24	Novartis Ag	Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
US6448293B1 (en) *	2000-03-31	2002-09-10	Pfizer Inc.	Diphenyl ether compounds useful in therapy
GB0019228D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
GB0022438D0 (en) *	2000-09-13	2000-11-01	Novartis Ag	Organic Compounds
US6479692B1 (en) *	2001-05-02	2002-11-12	Nobex Corporation	Methods of synthesizing acylanilides including bicalutamide and derivatives thereof
GB0202873D0 (en) *	2002-02-07	2002-03-27	Novartis Ag	Organic compounds
US20050124624A1 (en) *	2002-03-15	2005-06-09	Gilbert Richard E.	4-(4-methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-yl-amino)phenyl]-benzamide for threating ang ii-mediated diseases
GB2398565A (en) *	2003-02-18	2004-08-25	Cipla Ltd	Imatinib preparation and salts
JP5844508B2 (ja) *	2005-11-25	2016-01-20	ノバルティスアーゲー	メシル酸イマチニブのｆ結晶形

2005
- 2005-02-02 PE PE2005000124A patent/PE20051096A1/es not_active Application Discontinuation
- 2005-02-02 MY MYPI20050400A patent/MY144177A/en unknown
- 2005-02-02 AR ARP050100395A patent/AR047530A1/es not_active Application Discontinuation
- 2005-02-03 JP JP2006551802A patent/JP4937760B2/ja not_active Expired - Fee Related
- 2005-02-03 AU AU2005211514A patent/AU2005211514B2/en not_active Ceased
- 2005-02-03 TW TW094103446A patent/TWI347186B/zh not_active IP Right Cessation
- 2005-02-03 KR KR1020067015707A patent/KR20060135735A/ko not_active Ceased
- 2005-02-03 CA CA2553887A patent/CA2553887C/en not_active Expired - Fee Related
- 2005-02-03 NZ NZ548714A patent/NZ548714A/xx not_active IP Right Cessation
- 2005-02-03 EP EP05707165.6A patent/EP1713792B1/en not_active Expired - Lifetime
- 2005-02-03 RU RU2006131548/04A patent/RU2375355C2/ru not_active IP Right Cessation
- 2005-02-03 BR BRPI0507464-9A patent/BRPI0507464A/pt not_active IP Right Cessation
- 2005-02-03 WO PCT/EP2005/001077 patent/WO2005075454A2/en not_active Ceased
- 2005-02-03 CN CNB2005800032177A patent/CN100558723C/zh not_active Expired - Fee Related
- 2005-02-03 US US10/597,287 patent/US20080249104A1/en not_active Abandoned
- 2005-02-03 KR KR1020127025616A patent/KR20120127525A/ko not_active Ceased
2006
- 2006-07-19 ZA ZA200605972A patent/ZA200605972B/en unknown
- 2006-07-20 IL IL177005A patent/IL177005A/en unknown
- 2006-08-01 MA MA29225A patent/MA28428B1/fr unknown
- 2006-08-03 TN TNP2006000243A patent/TNSN06243A1/en unknown
- 2006-08-03 EC EC2006006752A patent/ECSP066752A/es unknown
- 2006-09-04 NO NO20063942A patent/NO20063942L/no not_active Application Discontinuation
2012
- 2012-02-08 US US13/368,811 patent/US8513256B2/en not_active Expired - Fee Related
2013
- 2013-01-22 PH PH12013500157A patent/PH12013500157A1/en unknown
- 2013-07-19 US US13/946,000 patent/US20140051853A1/en not_active Abandoned

Also Published As

Publication number	Publication date
KR20120127525A (ko)	2012-11-21
US20080249104A1 (en)	2008-10-09
JP4937760B2 (ja)	2012-05-23
RU2375355C2 (ru)	2009-12-10
ECSP066752A (es)	2006-11-16
KR20060135735A (ko)	2006-12-29
AU2005211514A1 (en)	2005-08-18
IL177005A (en)	2014-05-28
RU2006131548A (ru)	2008-03-10
PE20051096A1 (es)	2006-01-23
MY144177A (en)	2011-08-15
CN100558723C (zh)	2009-11-11
ZA200605972B (en)	2007-11-28
TW200529854A (en)	2005-09-16
PH12013500157A1 (en)	2014-09-08
CA2553887C (en)	2013-04-16
IL177005A0 (en)	2006-12-10
MA28428B1 (fr)	2007-02-01
AR047530A1 (es)	2006-01-25
US20140051853A1 (en)	2014-02-20
NZ548714A (en)	2009-08-28
TNSN06243A1 (en)	2007-12-03
EP1713792B1 (en)	2014-04-30
JP2007520518A (ja)	2007-07-26
CN1914191A (zh)	2007-02-14
EP1713792A2 (en)	2006-10-25
CA2553887A1 (en)	2005-08-18
BRPI0507464A (pt)	2007-07-10
TWI347186B (en)	2011-08-21
US20120142697A1 (en)	2012-06-07
US8513256B2 (en)	2013-08-20
WO2005075454A3 (en)	2006-07-27
AU2005211514B2 (en)	2009-09-10
WO2005075454A2 (en)	2005-08-18

Legal Events

Date	Code	Title	Description
2015-06-08	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20063942L (no)	2006-11-02	Saltformer av 4(-4-metylpiperazin-1-ylmetyl)-n-[4-metyl-3-(4-piperidin-3-yl)pyrimidin-2-ylamino)fenyl]-benzamid
PT998473E (pt)	2004-02-27	Modificacao da forma de cristal de um derivado de n-fenil-2-pirimidinoamina processos para a sua preparacao e sua utilizacao
EA201100638A1 (ru)	2011-10-31	Тригидрохлориды производного дигидроптеридинона и способы их получения
NO20055219L (no)	2006-01-04	Nye forbindelser
NO20063748L (no)	2006-08-22	Kinolinderivater og anvendelse derav som mykobakterielle inhibitorer
NO20076460L (no)	2008-02-19	Nye fluorenderivater, sammensetninger inneholdende nevnte derivater og anvendelse derav
CY1109299T1 (el)	2014-07-02	Μεθανοσουλφονικο αλας 3-[(2-{[4-εξυλοξυκαρβονυλαμινο-ιμινο-μεθυλο)-φαινυλαμινο]-μεθυλο}-1-μεθυλο-1η-βενζιμιδαζολο-5-καρβονυλο)-πυριδιν-2-υλο-αμινο]-προπιονικου αιθυλεστερα και η χρηση αυτου ως φαρμακευτικο μεσο
NO20082684L (no)	2008-08-15	F-, G-, H-, I- og K-krystallformer av imatinibmesylat
MX2009013272A (es)	2010-01-25	Formas amorfas estabilzadas de mesilato de imatinib.
PE20060298A1 (es)	2006-04-13	Derivados de acido carboxilico de bencimidazolona
NO20083068L (no)	2008-07-08	Optisk aktive karbamater, fremgangsmate for deres fremstilling og anvendelse derav som farmasoytiske mellomprodukter
WO2009065910A3 (en)	2009-12-30	Acid addition salts of imatinib and formulations comprising the same
NO20060379L (no)	2006-03-24	Den polymorfe form av 4-[6-acetyl-3-[3-(4-acetyl-3-hydroksy-2-propylfenyltio)propoksy]-2-propylfenoksybutansyre
PE20060964A1 (es)	2006-10-02	Forma cristalina b de clorhidrato de (3-cian-1h-indol-7-il)-[4-(4-fluorofenetil)-piperazin-1-il]-metanona y procedimiento de preparacion
NO20073758L (no)	2007-10-19	2-okso-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl-piperidiner anvendt som CGRP-antagonister
EA200801960A1 (ru)	2008-12-30	Соли дулоксетина
ES2421587T3 (es)	2013-09-04	Uso de derivados de pirimidilaminobenzamida para el tratamiento de mastocitosis sistémica
TH74677A (th)	2006-01-19	รูปเกลือของ 4-[(4-เมทธิลปิปเปอราซิน-1-อิลเมทธิล)-n-[4-เมทธิล-3-(4-ไพริดิน-3-อิล)ไพริมิดิน-2-อิลอะมิโน)เฟนนิล]-เบนซามีด
NO20054418L (no)	2005-09-23	Substituert benzoylureidopyridylpiperidin- og -pyrrolidinkarboksylsyrederivater, deres fremstilling og anvendelse
NO20064114L (no)	2006-12-08	Fremgangsmate for fremstilling av N-arylpiperazinderivater
IL171927A0 (en)	2006-04-10	Use of tyrosine kinase inhibitor to treat diabetes
WO2004026930A3 (en)	2004-09-23	The method for reducing inflammation using sti-571 or its salt
HK1097535A (en)	2007-06-29	Salt forms of 4-(4-methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide
RU2010135782A (ru)	2012-03-10	КРИСТАЛИЧЕСКАЯ η- МОДИФИКАЦИЯ 4-[(4-МЕТИЛ-1-ПИПЕРА-ЗИНИЛ)МЕТИЛ]-N-[4-МЕТИЛ-3-[[4-(3-ПИРИДИНИЛ)-2-ПИРИМИ-ДИНИЛ]-АМИНО]-ФЕНИЛ] БЕНЗАМИДА МЕТАНСУЛЬФОНАТА, СПОСОБ ЕЕ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕЕ ОСНОВЕ
ATE480534T1 (de)	2010-09-15	Kristallines variables hydrat von (s)-6-(4-(2-((3-(9h-carbazol-4-yloxy)-2-hydroxy ropyl)amino)-2- methylpropyl)phenoxy)-3-pyridincarbonsäureamid- hemisuccinatsalz