NO20063997L - Tablett med flere lag - Google Patents

Tablett med flere lag

Info

Publication number: NO20063997L
Authority: NO; Norway
Prior art keywords: immediate release; layer formulated; multilayer tablet; diuretic; optionally
Prior art date: 2004-02-20

Application number

NO20063997A

Other languages

English (en)

Norwegian (no)

Inventor

Anja Kohlrausch

Original Assignee

Boeheringer Ingelheim Internat

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-20

Filing date

2006-09-06

Publication date

2006-11-14

2006-09-06 Application filed by Boeheringer Ingelheim Internat filed Critical Boeheringer Ingelheim Internat

2006-11-14 Publication of NO20063997L publication Critical patent/NO20063997L/no

Links

239000012729 immediate-release (IR) formulation Substances 0.000 abstract 3
239000011159 matrix material Substances 0.000 abstract 3
239000003826 tablet Substances 0.000 abstract 3
239000002934 diuretic Substances 0.000 abstract 2
230000001882 diuretic effect Effects 0.000 abstract 2
RMMXLENWKUUMAY-UHFFFAOYSA-N telmisartan Chemical compound CCCC1=NC2=C(C)C=C(C=3N(C4=CC=CC=C4N=3)C)C=C2N1CC(C=C1)=CC=C1C1=CC=CC=C1C(O)=O RMMXLENWKUUMAY-UHFFFAOYSA-N 0.000 abstract 2
239000005541 ACE inhibitor Substances 0.000 abstract 1
101710129690 Angiotensin-converting enzyme inhibitor Proteins 0.000 abstract 1
101710086378 Bradykinin-potentiating and C-type natriuretic peptides Proteins 0.000 abstract 1
239000005537 C09CA07 - Telmisartan Substances 0.000 abstract 1
JZUFKLXOESDKRF-UHFFFAOYSA-N Chlorothiazide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NCNS2(=O)=O JZUFKLXOESDKRF-UHFFFAOYSA-N 0.000 abstract 1
239000002333 angiotensin II receptor antagonist Substances 0.000 abstract 1
229940126317 angiotensin II receptor antagonist Drugs 0.000 abstract 1
229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
229960002003 hydrochlorothiazide Drugs 0.000 abstract 1
HDACQVRGBOVJII-JBDAPHQKSA-N ramipril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](C[C@@H]2CCC[C@@H]21)C(O)=O)CC1=CC=CC=C1 HDACQVRGBOVJII-JBDAPHQKSA-N 0.000 abstract 1
229960003401 ramipril Drugs 0.000 abstract 1
239000007944 soluble tablet Substances 0.000 abstract 1
229960005187 telmisartan Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
- B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
- B30B11/085—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable for multi-layer articles

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Mechanical Engineering (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO20063997A 2004-02-20 2006-09-06 Tablett med flere lag NO20063997L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE102004008804A DE102004008804A1 (de)	2004-02-20	2004-02-20	Mehrschichttablette
PCT/EP2005/001498 WO2005079762A1 (fr)	2004-02-20	2005-02-15	Comprime multicouche

Publications (1)

Publication Number	Publication Date
NO20063997L true NO20063997L (no)	2006-11-14

Family

ID=34832975

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20063997A NO20063997L (no)	2004-02-20	2006-09-06	Tablett med flere lag

Country Status (20)

Country	Link
US (1)	US20050186274A1 (fr)
EP (1)	EP1718281A1 (fr)
JP (1)	JP2007523112A (fr)
KR (1)	KR20060130671A (fr)
CN (1)	CN1921840A (fr)
AR (1)	AR047806A1 (fr)
AU (1)	AU2005215115A1 (fr)
BR (1)	BRPI0507887A (fr)
CA (1)	CA2552902A1 (fr)
DE (1)	DE102004008804A1 (fr)
EC (1)	ECSP066779A (fr)
IL (1)	IL177536A0 (fr)
MX (1)	MXPA06008225A (fr)
NO (1)	NO20063997L (fr)
PE (1)	PE20051127A1 (fr)
RU (1)	RU2006133453A (fr)
TW (1)	TW200533389A (fr)
UY (1)	UY28753A1 (fr)
WO (1)	WO2005079762A1 (fr)
ZA (1)	ZA200604913B (fr)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005067887A2 (fr) *	2004-03-24	2005-07-28	Actavis Group	Formulations de ramipril
GB0518129D0 (en) *	2005-09-06	2005-10-12	Arrow Int Ltd	Ramipril formulation
GB2431579A (en) *	2005-10-28	2007-05-02	Arrow Int Ltd	Ramipril formulations
US20070098782A1 (en) *	2005-10-28	2007-05-03	Selamine Limited	Ramipril Formulation
US8637078B2 (en) *	2005-11-24	2014-01-28	Boehringer Ingelheim International Gmbh	Bilayer tablet comprising telmisartan and diuretic
WO2007095716A1 (fr) *	2006-02-23	2007-08-30	Iomedix Sleep International Srl	Compositions et méthodes pour l'induction et la conservation d'un sommeil de qualité
ES2523729T3 (es)	2006-06-16	2014-12-01	Lek Pharmaceuticals D.D.	Composición farmacéutica que comprende hidroclorotiazida y telmisartán
WO2008001184A2 (fr) *	2006-06-26	2008-01-03	Emcure Pharmaceuticals Limited	Composition solide
EP1908469A1 (fr) *	2006-10-06	2008-04-09	Boehringer Ingelheim Vetmedica Gmbh	Antagonistes du récepteur de l'angiotensine II pour traiter des désordres sistémiques des chats
WO2008049196A1 (fr) *	2006-10-27	2008-05-02	Iomedix Development International Srl	Compositions destinées à améliorer les niveaux de cholestérol dans le sang
GB0624090D0 (en) *	2006-12-01	2007-01-10	Selamine Ltd	Ramipril amine salts
GB0624084D0 (en) *	2006-12-01	2007-01-10	Selamine Ltd	Ramipril amino acid salts
GB0624087D0 (en) *	2006-12-01	2007-01-10	Selamine Ltd	Ramipril combination salt
EP1970053A1 (fr) *	2007-03-14	2008-09-17	Boehringer Ingelheim Pharma GmbH & Co. KG	Composition pharmaceutique
PL382311A1 (pl) *	2007-04-27	2008-11-10	Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna	Kompozycja farmaceutyczna o polepszonej stabilności zawierająca inhibitor acetylocholinoesterazy lub farmaceutycznie dopuszczalną jego sól oraz sposób jej wytwarzania
US20090060983A1 (en) *	2007-08-30	2009-03-05	Bunick Frank J	Method And Composition For Making An Orally Disintegrating Dosage Form
WO2009058950A2 (fr) *	2007-10-30	2009-05-07	Dr. Reddy's Laboratories Ltd.	Formulations pharmaceutiques comprenant du telmisartan et de l'hydrochlorotiazide
KR101560176B1 (ko) *	2007-10-31	2015-10-14	맥네일-피피씨, 인코포레이티드	구강내 붕해성 투여 형태
US20110008428A1 (en) *	2008-03-19	2011-01-13	Ratiopharm Gmbh	Solid pharmaceutical composition comprising a non-peptide angiotensin ii receptor antagonist and a diuretic
US10046081B2 (en)	2008-04-11	2018-08-14	The Henry M Jackson Foundation For The Advancement Of Military Medicine, Inc.	Electrospun dextran fibers and devices formed therefrom
SG176585A1 (en)	2009-05-20	2012-01-30	Boehringer Ingelheim Vetmed	Pharmaceutical oral telmisartan solution
US8858210B2 (en)	2009-09-24	2014-10-14	Mcneil-Ppc, Inc.	Manufacture of variable density dosage forms utilizing radiofrequency energy
US8343533B2 (en)	2009-09-24	2013-01-01	Mcneil-Ppc, Inc.	Manufacture of lozenge product with radiofrequency
RU2479310C2 (ru) *	2011-02-09	2013-04-20	Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН")	Фармацевтическая композиция для лечения артериальной гипертензии и застойной сердечной недостаточности и способ ее получения
CN102885789A (zh) *	2012-04-05	2013-01-23	常州制药厂有限公司	一种治疗高血压的复方制剂的制备方法
US9445971B2 (en)	2012-05-01	2016-09-20	Johnson & Johnson Consumer Inc.	Method of manufacturing solid dosage form
US9511028B2 (en)	2012-05-01	2016-12-06	Johnson & Johnson Consumer Inc.	Orally disintegrating tablet
US9233491B2 (en)	2012-05-01	2016-01-12	Johnson & Johnson Consumer Inc.	Machine for production of solid dosage forms
JP6018420B2 (ja) *	2012-06-05	2016-11-02	ニプロ株式会社	アンジオテンシンｉｉ受容体拮抗薬およびサイアザイド系利尿薬を含む医薬組成物
US9789066B2 (en)	2014-01-10	2017-10-17	Johnson & Johnson Consumer Inc.	Process for making tablet using radiofrequency and lossy coated particles
EP2979691A1 (fr) *	2014-07-30	2016-02-03	Boehringer Ingelheim International GmbH	Comprimé à désintégration orale
CA2990855A1 (fr) *	2015-06-26	2016-12-29	Abbvie Inc.	Compositions pharmaceutiques solides pour le traitement du vhc
CR20180088A (es) *	2015-07-17	2018-05-24	Abbvie Inc	Composiciones farmacéuticas sólidas para el tratamiento del vhc
US10828387B2 (en)	2015-11-12	2020-11-10	St. Teresa Medical, Inc.	Method of sealing a durotomy
US10493026B2 (en)	2017-03-20	2019-12-03	Johnson & Johnson Consumer Inc.	Process for making tablet using radiofrequency and lossy coated particles
US10953128B2 (en)	2017-11-02	2021-03-23	St. Teresa Medical, Inc.	Fibrin sealant products
WO2020109319A1 (fr)	2018-11-27	2020-06-04	Zaklady Farmaceutyczne Polpharma S.A	Composition pharmaceutique comprenant du ramipril et de l'indapamide
EP3996709A1 (fr)	2019-07-09	2022-05-18	Boehringer Ingelheim Vetmedica GmbH	Telmisartan pour le traitement de l'hypertension chez les chiens

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Publication number	Priority date	Publication date	Assignee	Title
TW483763B (en) *	1994-09-02	2002-04-21	Astra Ab	Pharmaceutical composition comprising of ramipril and dihydropyridine compound
DE4446468A1 (de) *	1994-12-23	1996-06-27	Basf Ag	Verfahren zur Herstellung von umhüllten Tabletten
US6087386A (en) *	1996-06-24	2000-07-11	Merck & Co., Inc.	Composition of enalapril and losartan
WO2000027397A1 (fr) *	1998-11-06	2000-05-18	Glaxo Group Limited	Medicaments antihypertenseurs a base de lacidipine et de telmisartan
GB0020691D0 (en) *	2000-08-22	2000-10-11	Boehringer Ingelheim Pharma	Pharmaceutical combination
EE200300075A (et) *	2000-08-22	2004-12-15	Boehringer Ingelheim Pharma Kg	Angiotensiin II antagonistide ja ACE inhibiitorite farmatseutiline kombinatsioon
US20030091630A1 (en) *	2001-10-25	2003-05-15	Jenny Louie-Helm	Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
JP2003144528A (ja) *	2001-11-15	2003-05-20	Fancl Corp	多層錠及びその製造方法

2004
- 2004-02-20 DE DE102004008804A patent/DE102004008804A1/de not_active Withdrawn
2005
- 2005-02-10 US US11/056,081 patent/US20050186274A1/en not_active Abandoned
- 2005-02-15 JP JP2006553509A patent/JP2007523112A/ja active Pending
- 2005-02-15 EP EP05707394A patent/EP1718281A1/fr not_active Withdrawn
- 2005-02-15 RU RU2006133453/15A patent/RU2006133453A/ru not_active Application Discontinuation
- 2005-02-15 CN CNA2005800052700A patent/CN1921840A/zh active Pending
- 2005-02-15 KR KR1020067019409A patent/KR20060130671A/ko not_active Withdrawn
- 2005-02-15 WO PCT/EP2005/001498 patent/WO2005079762A1/fr not_active Ceased
- 2005-02-15 CA CA002552902A patent/CA2552902A1/fr not_active Abandoned
- 2005-02-15 AU AU2005215115A patent/AU2005215115A1/en not_active Abandoned
- 2005-02-15 MX MXPA06008225A patent/MXPA06008225A/es unknown
- 2005-02-15 BR BRPI0507887-3A patent/BRPI0507887A/pt not_active IP Right Cessation
- 2005-02-17 UY UY28753A patent/UY28753A1/es not_active Application Discontinuation
- 2005-02-18 TW TW094104757A patent/TW200533389A/zh unknown
- 2005-02-18 AR ARP050100579A patent/AR047806A1/es unknown
- 2005-02-18 PE PE2005000192A patent/PE20051127A1/es not_active Application Discontinuation
2006
- 2006-06-14 ZA ZA200604913A patent/ZA200604913B/en unknown
- 2006-08-17 IL IL177536A patent/IL177536A0/en unknown
- 2006-08-21 EC EC2006006779A patent/ECSP066779A/es unknown
- 2006-09-06 NO NO20063997A patent/NO20063997L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL177536A0 (en)	2006-12-10
CN1921840A (zh)	2007-02-28
ZA200604913B (en)	2007-11-28
TW200533389A (en)	2005-10-16
AU2005215115A1 (en)	2005-09-01
BRPI0507887A (pt)	2007-08-07
DE102004008804A1 (de)	2005-09-08
MXPA06008225A (es)	2006-08-31
AR047806A1 (es)	2006-02-22
UY28753A1 (es)	2005-09-30
WO2005079762A1 (fr)	2005-09-01
KR20060130671A (ko)	2006-12-19
CA2552902A1 (fr)	2005-09-01
US20050186274A1 (en)	2005-08-25
ECSP066779A (es)	2006-12-20
EP1718281A1 (fr)	2006-11-08
JP2007523112A (ja)	2007-08-16
RU2006133453A (ru)	2008-03-27
PE20051127A1 (es)	2006-01-31

Legal Events

Date	Code	Title	Description
2009-10-05	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
ECSP066779A (es)	2006-12-20	Comprimido multicapas
NO20071375L (no)	2007-05-10	Bilags tablett.
NO20071514L (no)	2007-03-22	Tolags tablett inneholdende Telmisartan og Amlodipin
IL194933A0 (en)	2009-08-03	A method for the preparation of amorphous telmisartane
WO2009058950A3 (fr)	2009-07-16	Formulations pharmaceutiques comprenant du telmisartan et de l'hydrochlorotiazide
DE122012000018I1 (de)	2012-06-06	Benzimidazolderivate und ihre verwendung als antagonisten des a II rezeptors.
NO20073396L (no)	2007-09-10	Farmasoytiske kombinasjoner av en angiotensinreceptorantagonist og en NEP-inhibitor
CL2011001091A1 (es)	2011-10-28	Forma de dosificacion farmaceutica oral solida que comprende en su nucleo nifedipino o nisoldipino y en un revestimiento de manto alrededor del nucleo al menos un antagonista de angiotensina ii y/o al menos un diuretico; procedimiento para su preparacion, util para tratar hipertension.
ECSP105695A (es)	2010-03-31	Proceso para la fabricacion de valsartan
EA201001312A1 (ru)	2011-04-29	Твердая фармацевтическая композиция, содержащая непептидный антагонист рецептора ангиотензина ii и диуретик
CL2007003613A1 (es)	2008-07-11	Compuestos nitroderivados, antagonistas del receptor de angiotensina ii; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar hipertension.
WO2005011652A3 (fr)	2005-06-23	Utilisation de vitamines d pour le traitement de maladie rénale
ECSP066727A (es)	2006-10-31	Reacciones de acoplamiento útiles en la preparación de derivados de (1h-tetrazol-5-il)-bifenilo
DK1553944T3 (da)	2008-06-23	Farmaceutisk præparat, hvori kombineres tenatoprazol og en histamin-H2-receptorantagonist
AR035223A1 (es)	2004-05-05	Tableta farmaceutica bicapa que comprende telmisartan y un diuretico, y preparacion de la misma.
WO2007017469A3 (fr)	2007-08-02	Procede de preparation d'un antagoniste des recepteurs de l'angiotensine ii
DK1919483T3 (da)	2010-05-10	Kombinationspræparat af et thiazidiuretikum og et loop-diuretikum