NO20064450L - Pyrazolo [3,4- β] Pyridin-forbindelse og dennes anvendelse som PDE4-inhibitor - Google Patents

Pyrazolo [3,4- β] Pyridin-forbindelse og dennes anvendelse som PDE4-inhibitor

Info

Publication number: NO20064450L
Authority: NO; Norway
Prior art keywords: compound; pyrazolo; mammal; provides; salt
Prior art date: 2004-03-16

Application number

NO20064450A

Other languages

English (en)

Norwegian (no)

Inventor

Martin Redpath Johnson

Paul Spencer Jones

Caroline Mary Cook

Iv Siegfried Benja Christensen

Christopher David Edlin

Mika Kristian Lindvall

Naimisha Trivedi

Amyn Pyarali Sayani

Lionel Trottet

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-03-16

Filing date

2006-10-02

Publication date

2006-11-14

2004-03-16 Priority claimed from GB0405893A external-priority patent/GB0405893D0/en

2005-03-14 Priority claimed from GB0505214A external-priority patent/GB0505214D0/en

2006-10-02 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2006-11-14 Publication of NO20064450L publication Critical patent/NO20064450L/no

Links

-1 pyridine compound Chemical class 0.000 title abstract 2
229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 title 1
239000002587 phosphodiesterase IV inhibitor Substances 0.000 title 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 title 1
JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 4
150000003839 salts Chemical class 0.000 abstract 4
241000124008 Mammalia Species 0.000 abstract 3
230000002265 prevention Effects 0.000 abstract 2
238000011200 topical administration Methods 0.000 abstract 2
208000028698 Cognitive impairment Diseases 0.000 abstract 1
206010012438 Dermatitis atopic Diseases 0.000 abstract 1
102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
208000026935 allergic disease Diseases 0.000 abstract 1
201000008937 atopic dermatitis Diseases 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
208000010877 cognitive disease Diseases 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
230000002757 inflammatory effect Effects 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Immunology (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Communicable Diseases (AREA)
Heart & Thoracic Surgery (AREA)
Otolaryngology (AREA)
Oncology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)

NO20064450A 2004-03-16 2006-10-02 Pyrazolo [3,4- β] Pyridin-forbindelse og dennes anvendelse som PDE4-inhibitor NO20064450L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0405893A GB0405893D0 (en)	2004-03-16	2004-03-16	Compounds
GB0505214A GB0505214D0 (en)	2005-03-14	2005-03-14	Compounds
PCT/EP2005/003038 WO2005090352A1 (fr)	2004-03-16	2005-03-15	Compose de pyrazolo[3,4-b]pyridine, et son utilisation en tant qu'inhibiteur de pdea4

Publications (1)

Publication Number	Publication Date
NO20064450L true NO20064450L (no)	2006-11-14

Family

ID=34962723

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20064450A NO20064450L (no)	2004-03-16	2006-10-02	Pyrazolo [3,4- β] Pyridin-forbindelse og dennes anvendelse som PDE4-inhibitor

Country Status (15)

Country	Link
US (2)	US7709497B2 (fr)
EP (2)	EP1735314A1 (fr)
JP (2)	JP2007529486A (fr)
KR (1)	KR20060130744A (fr)
AR (1)	AR048175A1 (fr)
AU (1)	AU2005223351A1 (fr)
BR (1)	BRPI0508843A (fr)
CA (1)	CA2559629A1 (fr)
IL (1)	IL178011A0 (fr)
MA (1)	MA28531B1 (fr)
NO (1)	NO20064450L (fr)
PE (1)	PE20060078A1 (fr)
RU (1)	RU2378274C2 (fr)
TW (1)	TW200602051A (fr)
WO (2)	WO2005090354A1 (fr)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
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GB0230045D0 (en)	2002-12-23	2003-01-29	Glaxo Group Ltd	Compounds
WO2005058892A1 (fr) *	2003-12-19	2005-06-30	Glaxo Group Limited	Composes pyrazolo [3,4-b] pyridine et leur utilisation en tant qu'inhibiteurs de la phosphodiesterase
AU2005223351A1 (en)	2004-03-16	2005-09-29	Glaxo Group Limited	Pyrazolo[3,4-b]pyridine compound, and its use as a PDE4 inhibitor
KR20090003349A (ko)	2006-04-20	2009-01-09	글락소 그룹 리미티드	화합물
AR061571A1 (es)	2006-06-23	2008-09-03	Smithkline Beecham Corp	Compuesto sal del acido toluenosulfonico de 4-{[6-cloro-3-({[(2- cloro-3-fluorofenil) amino]carbonil} amino)- 2- hidroxifenil]sulfonil] -1- piperazinacarbxilato de 1.1-dimetiletilo, composicion farmaceutica que lo comprende su uso para la fabricacion de un medicamento combinacion farmaceutica con un
CA2659539A1 (fr)	2006-08-01	2008-02-07	Glaxo Group Limited	Composes de pyrazolo[3,4-b]pyridine et leur utilisation en tant qu'inhibiteurs de pde4
PE20081889A1 (es)	2007-03-23	2009-03-05	Smithkline Beecham Corp	Indol carboxamidas como inhibidores de ikk2
PE20091563A1 (es)	2008-02-06	2009-11-05	Glaxo Group Ltd	Farmacoforos duales - antagonistas muscarinicos de pde4
PE20091553A1 (es)	2008-02-06	2009-10-30	Glaxo Group Ltd	Farmacoforos duales - antagonistas muscarinicos de pde4
AR070562A1 (es)	2008-02-06	2010-04-21	Glaxo Group Ltd	Farmacoforos duales - antagonistas muscarinicos de pde4
WO2009100169A1 (fr) *	2008-02-06	2009-08-13	Glaxo Group Limited	Pharmacophores duals, antagonistes des récepteurs muscariniques et inhibiteurs de l'activité pde4
GB0806900D0 (en) *	2008-04-16	2008-05-21	Dow Corning	Fabric care emulsions
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WO2011067366A1 (fr)	2009-12-03	2011-06-09	Glaxo Group Limited	Dérivés d'indazole comme inhibiteurs des pi3-kinases
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2005
- 2005-03-15 AU AU2005223351A patent/AU2005223351A1/en not_active Abandoned
- 2005-03-15 KR KR1020067021438A patent/KR20060130744A/ko not_active Ceased
- 2005-03-15 US US10/598,838 patent/US7709497B2/en not_active Expired - Fee Related
- 2005-03-15 JP JP2007503404A patent/JP2007529486A/ja active Pending
- 2005-03-15 EP EP05716291A patent/EP1735314A1/fr not_active Withdrawn
- 2005-03-15 US US10/598,973 patent/US20080275078A1/en not_active Abandoned
- 2005-03-15 WO PCT/GB2005/000987 patent/WO2005090354A1/fr not_active Ceased
- 2005-03-15 RU RU2006132684/04A patent/RU2378274C2/ru not_active IP Right Cessation
- 2005-03-15 EP EP05718039A patent/EP1740590A1/fr not_active Withdrawn
- 2005-03-15 WO PCT/EP2005/003038 patent/WO2005090352A1/fr not_active Ceased
- 2005-03-15 BR BRPI0508843-7A patent/BRPI0508843A/pt not_active IP Right Cessation
- 2005-03-15 JP JP2007503306A patent/JP2007529464A/ja active Pending
- 2005-03-15 CA CA002559629A patent/CA2559629A1/fr not_active Abandoned
- 2005-03-16 AR ARP050101028A patent/AR048175A1/es not_active Application Discontinuation
- 2005-03-16 TW TW094108054A patent/TW200602051A/zh unknown
- 2005-03-16 PE PE2005000299A patent/PE20060078A1/es not_active Application Discontinuation
2006
- 2006-09-11 IL IL178011A patent/IL178011A0/en unknown
- 2006-10-02 NO NO20064450A patent/NO20064450L/no not_active Application Discontinuation
- 2006-10-13 MA MA29385A patent/MA28531B1/fr unknown

Also Published As

Publication number	Publication date
IL178011A0 (en)	2006-12-31
AU2005223351A1 (en)	2005-09-29
WO2005090352A1 (fr)	2005-09-29
MA28531B1 (fr)	2007-04-03
JP2007529464A (ja)	2007-10-25
RU2378274C2 (ru)	2010-01-10
AR048175A1 (es)	2006-04-05
US20080275078A1 (en)	2008-11-06
US7709497B2 (en)	2010-05-04
WO2005090354A1 (fr)	2005-09-29
TW200602051A (en)	2006-01-16
EP1740590A1 (fr)	2007-01-10
RU2006132684A (ru)	2008-04-27
CA2559629A1 (fr)	2005-09-29
BRPI0508843A (pt)	2007-08-28
JP2007529486A (ja)	2007-10-25
PE20060078A1 (es)	2006-03-10
EP1735314A1 (fr)	2006-12-27
KR20060130744A (ko)	2006-12-19
US20070280971A1 (en)	2007-12-06

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Date	Code	Title	Description
2011-10-24	FC2A	Withdrawal, rejection or dismissal of laid open patent application

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