NO20065902L - 3-{4-(pyridin-3-yl)fenyl}-5-(1H-,1,2,3-triazol-1-ylmetyl)-1,3-oksazolidin-2-oner som antibakterielle midler - Google Patents

3-{4-(pyridin-3-yl)fenyl}-5-(1H-,1,2,3-triazol-1-ylmetyl)-1,3-oksazolidin-2-oner som antibakterielle midler

Info

Publication number
NO20065902L
NO20065902L NO20065902A NO20065902A NO20065902L NO 20065902 L NO20065902 L NO 20065902L NO 20065902 A NO20065902 A NO 20065902A NO 20065902 A NO20065902 A NO 20065902A NO 20065902 L NO20065902 L NO 20065902L
Authority
NO
Norway
Prior art keywords
oxazolidin
triazol
ylmethyl
pyridin
phenyl
Prior art date
Application number
NO20065902A
Other languages
English (en)
Inventor
Michael Barry Gravestock
Fei Zhou
Folkert Beck
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0411592A external-priority patent/GB0411592D0/en
Priority claimed from GB0500053A external-priority patent/GB0500053D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20065902L publication Critical patent/NO20065902L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Forbindelser med formel I, samt farmasøytisk akseptable salter og prodrugs derav, er beskrevet, hvor R1, R2, R3 og R4 er som definert heri. Også beskrevet er fremgangsmåter for fremstilling av forbindelser med formel I samt fremgangsmåter for anvendelse av forbindelser med formel I for behandling av bakterielle infeksjoner.
NO20065902A 2004-05-25 2006-12-19 3-{4-(pyridin-3-yl)fenyl}-5-(1H-,1,2,3-triazol-1-ylmetyl)-1,3-oksazolidin-2-oner som antibakterielle midler NO20065902L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0411592A GB0411592D0 (en) 2004-05-25 2004-05-25 Chemical compounds
GB0500053A GB0500053D0 (en) 2005-01-05 2005-01-05 Chemical compounds
PCT/GB2005/002055 WO2005116023A1 (en) 2004-05-25 2005-05-24 3- {4- (pyridin-3-yl) phenyl} -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents

Publications (1)

Publication Number Publication Date
NO20065902L true NO20065902L (no) 2007-02-20

Family

ID=34968777

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065902A NO20065902L (no) 2004-05-25 2006-12-19 3-{4-(pyridin-3-yl)fenyl}-5-(1H-,1,2,3-triazol-1-ylmetyl)-1,3-oksazolidin-2-oner som antibakterielle midler

Country Status (9)

Country Link
US (1) US20080021071A1 (no)
EP (1) EP1753755A1 (no)
JP (1) JP2008500318A (no)
AU (1) AU2005247670A1 (no)
BR (1) BRPI0511524A (no)
CA (1) CA2567929A1 (no)
IL (1) IL179347A0 (no)
NO (1) NO20065902L (no)
WO (1) WO2005116023A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100854211B1 (ko) * 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
WO2010042887A2 (en) 2008-10-10 2010-04-15 Trius Therapeutics Methods for preparing oxazolidinones and compositions containing them
BRPI1008829A2 (pt) 2009-02-03 2016-03-15 Trius Therapeutics forma cristalina de dihidrogenofosfato de (r)-3-(4-(2-(2-metiltetrazol-5-il) piridin-5-il)-3-fluorofenil)-5-hidroximetil oxazolidin-2-ona
US8580767B2 (en) * 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
CN102260277B (zh) * 2010-05-24 2013-07-24 中国科学院上海药物研究所 新型苯并噁嗪噁唑烷酮类化合物及其制备方法和用途
US9365530B2 (en) 2012-05-07 2016-06-14 The University Of North Carolina At Chapel Hill Direct anti-markovnikov addition of acids to alkenes
WO2014179648A2 (en) * 2013-05-02 2014-11-06 The University Of North Carolina At Chapel Hill Direct anti-markovnikov addition of acids to alkenes
WO2016061772A1 (en) 2014-10-22 2016-04-28 Merck Sharp & Dohme Corp. Nargenicin compounds and uses thereof as antibacterial agents
KR102375929B1 (ko) 2016-03-31 2022-03-16 온크터널 테라퓨틱스, 인코포레이티드. 인돌린 유사체 및 이의 용도
JP7805319B2 (ja) 2020-06-18 2026-01-23 アカゲラ・メディスンズ，インコーポレイテッド オキサゾリジノン化合物、オキサゾリジノン化合物を含むリポソーム組成物、およびそれらの使用方法
CA3200234A1 (en) 2020-11-25 2022-06-02 Daryl C. Drummond Lipid nanoparticles for delivery of nucleic acids, and related methods of use
EP4531819A2 (en) 2022-05-25 2025-04-09 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254577A (en) * 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
BR0111280A (pt) * 2000-06-05 2003-06-10 Dong A Pharm Co Ltd Novos derivados de oxazolidinona e um processo para a preparação dos mesmos
AU2003207340A1 (en) * 2002-02-28 2003-09-09 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
WO2004048350A2 (en) * 2002-11-28 2004-06-10 Astrazeneca Ab Oxazolidinones as antibacterial agents
AU2004267007C1 (en) * 2003-06-03 2010-04-29 Melinta Subsidiary Corp. Biaryl heterocyclic compounds and methods of making and using the same
JP2007521283A (ja) * 2003-07-02 2007-08-02 メルク アンド カンパニー インコーポレーテッド シクロプロピル基で置換されたオキサゾリジノン系抗生物質およびその誘導体
JP2007514782A (ja) * 2003-12-17 2007-06-07 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ハロゲン化ビアリール複素環式化合物ならびにその作製方法および使用方法

Also Published As

Publication number Publication date
CA2567929A1 (en) 2005-12-08
EP1753755A1 (en) 2007-02-21
WO2005116023A8 (en) 2007-01-11
IL179347A0 (en) 2007-03-08
AU2005247670A1 (en) 2005-12-08
BRPI0511524A (pt) 2007-12-26
JP2008500318A (ja) 2008-01-10
US20080021071A1 (en) 2008-01-24
WO2005116023A1 (en) 2005-12-08

Similar Documents

Publication Publication Date Title
NO20054852L (no) GFAT inhibitorer
NO20091409L (no) Pyridin-3-yl-derivater som immunmodulerende midler
SG128491A1 (en) Heterocyclic sulfonamide inhibitors of beta amyloid production
NO20076066L (no) Oksadiazolderivater som DGAT-inhibitorer
NO20071642L (no) N-Benzensulfonylsubstituerte anilino-pyrimidinanaloger
NO20044866L (no) Pyrazolo-pyrimidin-anilin-forbindelser anvendelige som kinase-inhibitorer
NO20060665L (no) N-substituerte pyrazolyl-amidyl-benzimidazolyl C-kit inhibitorer
NO20085066L (no) 4,5-difenyl-pyrimidinyl-aminosubstituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter
NO20082389L (no) 2,3,4-trifenylimidazolinderivater som inhibitor av interaksjonen mellom P53- og MDM2-proteiner for anvendelse som antikreftmidler
NO20075059L (no) Nye forbindelser II 2-pyridinderivater som inhibitorer av neutrofil elastase
EP1163910A4 (en) PREVENTIVE / MEDICINE AGAINST INTERSTITIAL PNEUMONIA AND PULMONAL FIBROSIS
NO20076695L (no) Nye MCHR1-antagonister og deres anvendelse for behandling av MCHR1-medierte tilstander og forstyrrelser
NO20082112L (no) 3-Amino-2-arylpropylazaindoler og deres anvendelse
NO20072753L (no) 3-Etylidenhydrazinosubstituerte heterocykliske forbindelser som trombopoietinreseptoraktivatorer
DK1888063T3 (da) Antimykotiske midler
IL183373A0 (en) 3-[2-(3-acylamino-2-oxo-2h-pyridin-1-yl)-acetylamino]-4-oxo-pentanoic acid derivatives, pharmaceutical compositions containing the same and methods for the preparation thereof
NO20071319L (no) Fremgangsmate for fremstilling av isotiazolderivater.
NO20060147L (no) Benzimidazolderivater, sammensetninger som inneholder slike, fremstilling derav og anvendelse derav
NO20065327L (no) Fremgangsmate for fremstilling av derivarer av 5-'4-(2-hydroksy-propyl)-3,5-dihydro-3H'1, 2,4(triazin-2-yl)-benzamid.
NO20054135L (no) Kipolinon/benzoksazin derivater og anvendelser derav
GEP20084437B (en) Novel lincomycin derivatives possessing antimicrobial activity
NO20052182L (no) Nye forbindelser
NO20062453L (no) Tiozolidinoner, fremstilling og anvendelse derav som legemidler
NO20062491L (no) Benzoksazinderivter og deres anvendelse
NO20044548L (no) Fremgangsmate for fremstilling av 6-alkaliden-penemderivater

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application