NO20071485L - Kjemiske substanser. - Google Patents

Kjemiske substanser.

Info

Publication number
NO20071485L
NO20071485L NO20071485A NO20071485A NO20071485L NO 20071485 L NO20071485 L NO 20071485L NO 20071485 A NO20071485 A NO 20071485A NO 20071485 A NO20071485 A NO 20071485A NO 20071485 L NO20071485 L NO 20071485L
Authority
NO
Norway
Prior art keywords
chemical substances
fatty acid
acid derivatives
unsaturated fatty
relates
Prior art date
Application number
NO20071485A
Other languages
English (en)
Other versions
NO331891B1 (no
Inventor
Finn Myhren
Marit Liland Sandvold
Ole Henrik Eriksen
Steinar Hagen
Original Assignee
Clavis Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clavis Pharma As filed Critical Clavis Pharma As
Priority to NO20071485A priority Critical patent/NO331891B1/no
Priority to CN200880008837A priority patent/CN101687904A/zh
Priority to RU2009138488/04A priority patent/RU2462472C2/ru
Priority to AU2008227246A priority patent/AU2008227246B2/en
Priority to MX2009009838A priority patent/MX2009009838A/es
Priority to US12/531,214 priority patent/US9428540B2/en
Priority to CA002680155A priority patent/CA2680155A1/en
Priority to JP2010500862A priority patent/JP2010522233A/ja
Priority to UAA200910594A priority patent/UA96794C2/ru
Priority to KR1020097021890A priority patent/KR20090123961A/ko
Priority to PCT/NO2008/000096 priority patent/WO2008115069A2/en
Priority to NZ579382A priority patent/NZ579382A/en
Priority to EP08741696A priority patent/EP2121723A2/en
Priority to TW097109460A priority patent/TWI428133B/zh
Publication of NO20071485L publication Critical patent/NO20071485L/no
Priority to IL200655A priority patent/IL200655A0/en
Priority to ZA200906226A priority patent/ZA200906226B/xx
Publication of NO331891B1 publication Critical patent/NO331891B1/no
Priority to JP2013105719A priority patent/JP2014012657A/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Den foreliggende oppfinnelsen vedrører visse umettede fettsyrederivater av terapeutisk aktive glukokortikostereoider og farmasøytiske formuleringer som inneholder slike.
NO20071485A 2007-03-20 2007-03-20 Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS NO331891B1 (no)

Priority Applications (17)

Application Number Priority Date Filing Date Title
NO20071485A NO331891B1 (no) 2007-03-20 2007-03-20 Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS
KR1020097021890A KR20090123961A (ko) 2007-03-20 2008-03-13 항염증제 및 항암제로서 글루코코르티코이드의 지방산 에스테르
PCT/NO2008/000096 WO2008115069A2 (en) 2007-03-20 2008-03-13 Fatty acid esters of glucocorticoids as anti-inflammatory and anti-cancer agents
AU2008227246A AU2008227246B2 (en) 2007-03-20 2008-03-13 Fatty acid esters of glucocorticoids as anti-inflammatory and anti-cancer agents
MX2009009838A MX2009009838A (es) 2007-03-20 2008-03-13 Esteres de acidos grasos de glucocorticoides como agentes antiinflamatorios y anti-cancer.
US12/531,214 US9428540B2 (en) 2007-03-20 2008-03-13 Fatty acid esters of glucocorticoids as anti-inflammatory and anti-cancer agents
CA002680155A CA2680155A1 (en) 2007-03-20 2008-03-13 Fatty acid esters of glucocorticoids as anti-inflammatory and anti-cancer agents
JP2010500862A JP2010522233A (ja) 2007-03-20 2008-03-13 抗炎症剤及び抗癌剤であるグルココルチコイドの脂肪酸エステル
UAA200910594A UA96794C2 (ru) 2007-03-20 2008-03-13 Глюкокортикоиды, способ их применения, способ лечения и фармацевтическая композиция на их основе
CN200880008837A CN101687904A (zh) 2007-03-20 2008-03-13 作为抗炎和抗癌药剂的糖皮质激素的脂肪酸脂
RU2009138488/04A RU2462472C2 (ru) 2007-03-20 2008-03-13 Химические соединения
NZ579382A NZ579382A (en) 2007-03-20 2008-03-13 Fatty acid esters of glucocorticoids as anti-inflammatory and anti-cancer agents
EP08741696A EP2121723A2 (en) 2007-03-20 2008-03-13 Fatty acid esters of glucocorticoids as anti-inflammatory and anti-cancer agents
TW097109460A TWI428133B (zh) 2007-03-20 2008-03-18 作為抗發炎劑及抗癌劑之糖皮質素的脂肪酸酯
IL200655A IL200655A0 (en) 2007-03-20 2009-08-31 Fatty acid esters of glucocorticoids as anti-inflammatory and anti-cancer agents
ZA200906226A ZA200906226B (en) 2007-03-20 2009-09-08 Fatty acid esters of glucocorticoids as anti-inflammatory and anti-cancer agents
JP2013105719A JP2014012657A (ja) 2007-03-20 2013-05-20 抗炎症剤及び抗癌剤であるグルココルチコイドの脂肪酸エステル

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO20071485A NO331891B1 (no) 2007-03-20 2007-03-20 Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS

Publications (2)

Publication Number Publication Date
NO20071485L true NO20071485L (no) 2008-09-22
NO331891B1 NO331891B1 (no) 2012-04-30

Family

ID=39734182

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071485A NO331891B1 (no) 2007-03-20 2007-03-20 Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS

Country Status (16)

Country Link
US (1) US9428540B2 (no)
EP (1) EP2121723A2 (no)
JP (2) JP2010522233A (no)
KR (1) KR20090123961A (no)
CN (1) CN101687904A (no)
AU (1) AU2008227246B2 (no)
CA (1) CA2680155A1 (no)
IL (1) IL200655A0 (no)
MX (1) MX2009009838A (no)
NO (1) NO331891B1 (no)
NZ (1) NZ579382A (no)
RU (1) RU2462472C2 (no)
TW (1) TWI428133B (no)
UA (1) UA96794C2 (no)
WO (1) WO2008115069A2 (no)
ZA (1) ZA200906226B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497292B2 (en) 2005-12-28 2013-07-30 Translational Therapeutics, Inc. Translational dysfunction based therapeutics
NO331891B1 (no) 2007-03-20 2012-04-30 Clavis Pharma Asa Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS
GB201006181D0 (en) 2010-04-14 2010-06-02 Ayanda As Composition
PT105723B (pt) * 2011-05-26 2014-03-24 Hovione Farmaci Ncia S A Método para a preparação de compostos orgânicos biologicamente activos
US9155747B2 (en) * 2012-09-13 2015-10-13 Chiesi Farmaceutici S.P.A. Isoxazolidine derivatives
US20180126000A1 (en) 2016-06-02 2018-05-10 Abbvie Inc. Glucocorticoid receptor agonist and immunoconjugates thereof
WO2018159808A1 (ja) * 2017-03-03 2018-09-07 国立研究開発法人国立がん研究センター 抗ｉｌ－７ｒ抗体の抗体薬物コンジュゲートと、がんまたは炎症を処置することに用いるための、抗ｉｌ－７ｒ抗体と細胞傷害剤との抗体薬物コンジュゲートを含む医薬組成物
CN108659090A (zh) * 2017-03-31 2018-10-16 天津药业研究院有限公司 一种17β-硫代羧酸氯甲酯类甾体化合物的制备方法
BR112020010694A2 (pt) 2017-12-01 2020-11-10 Abbvie Inc. agonista de receptor de glicocorticoides e imunoconjugados do mesmo

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1227992A (no) * 1968-01-23 1971-04-15 Koninklijke Gist Spiritus
IT1043956B (it) * 1970-10-17 1980-02-29 Isf Spa 21 esteri di acidi grassi insaturi del desa e beta metazone
BE887518A (fr) 1980-02-15 1981-08-13 Glaxo Group Ltd Cartothioates d'androstanes
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
JPH0381286A (ja) * 1989-08-22 1991-04-05 Green Cross Corp:The ステロイド外用剤
JPH05132498A (ja) * 1991-11-08 1993-05-28 Asahi Glass Co Ltd ステロイド誘導体およびその製剤
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
CN1243799C (zh) 2000-03-24 2006-03-01 Dsmip财产有限公司 适合高速涂布光学纤维的可辐射－固化涂层
GB0017988D0 (en) * 2000-07-21 2000-09-13 Glaxo Group Ltd Novel process
GB0202563D0 (en) 2002-02-04 2002-03-20 Glaxo Group Ltd Process
AU2003291634A1 (en) * 2002-10-08 2004-05-04 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
NO331891B1 (no) 2007-03-20 2012-04-30 Clavis Pharma Asa Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS

Also Published As

Publication number Publication date
NZ579382A (en) 2011-09-30
US9428540B2 (en) 2016-08-30
JP2010522233A (ja) 2010-07-01
MX2009009838A (es) 2010-01-15
ZA200906226B (en) 2010-05-26
CN101687904A (zh) 2010-03-31
TWI428133B (zh) 2014-03-01
TW200846010A (en) 2008-12-01
IL200655A0 (en) 2010-05-17
WO2008115069A3 (en) 2008-11-13
US20100099654A1 (en) 2010-04-22
EP2121723A2 (en) 2009-11-25
WO2008115069A2 (en) 2008-09-25
JP2014012657A (ja) 2014-01-23
CA2680155A1 (en) 2008-09-25
RU2462472C2 (ru) 2012-09-27
UA96794C2 (ru) 2011-12-12
AU2008227246B2 (en) 2012-06-14
KR20090123961A (ko) 2009-12-02
RU2009138488A (ru) 2011-04-27
AU2008227246A1 (en) 2008-09-25
NO331891B1 (no) 2012-04-30

Similar Documents

Publication Publication Date Title
NO20071485L (no) Kjemiske substanser.
NO20073601L (no) Immunresponsmodifikator-skumformuleringer
CY1123549T1 (el) Σταθερη φαρμακευτικη συνθεση και μεθοδοι χρησης αυτης
MY142589A (en) Benzimidazole derivatives : preparation and pharmaceutical applications
EA201270666A1 (ru) Соединения и фармацевтические композиции для снижения уровня мочевой кислоты
CR20110599A (es) Composiciones farmacéuticamente activas que comprenden moduladores de estrés oxidativo (osm), nuevas entidades químicas, composiciones y usos
UA110612C2 (uk) Похідні 1-аміно-2-циклопропілетилборонової кислоти
MA32200B1 (fr) Nouvelles formulations,comprimes comprenant de telles formulations, leur utilisation et leur procede de preparation
UY31080A1 (es) Derivados de pirazol sustituidos con heteroarilo utiles para tratar trastornos hiperproliferativos y enfermedades asociadas con angiogénesis
EA201170508A1 (ru) Производные 1-амино-2-циклобутилэтилбороновой кислоты
ECSP088214A (es) Formulaciones de acetato de bazedoxifeno que tienen una conversión polimórfica reducida
NO20080220L (no) Formuleringer med hoy medikament belastning og doseringsformer
EP2468771A4 (en) PHARMACEUTICAL COMPOSITION WITH AN ANTIBODY TO HB-EGF AS AN ACTIVE SUBSTANCE
MX2012005689A (es) Analogos de acido araquidonico y metodos para el tratamiento analgesico utilizando los mismos.
UY29395A1 (es) Formulación de medicamentos conteniendo vardenafilo.
WO2011161396A3 (en) Disinfectant composition
NO20084478L (no) Konjugerte lipidderivater
FR2902007B1 (fr) Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s) ainsi que leurs applications notamment therapeutiques
BR112012029697A2 (pt) polissacarídeo da semente de tamarindo para uso no tratamento de doenças inflamatórias
AR070392A1 (es) Composiciones de tabletas de ranitidina de desintegracion oral y sus metodos de eleboracion
BR112015000647A2 (pt) composições orais líquidas e pediátricas que contêm nepadutant
CY1107277T1 (el) Βενζισοξαζολες
GT200800178A (es) Asociacion entre un antiaterotrombotico y un inhibidor de la enzima de conversion de la angiotensina
ECSP099801A (es) COMPOSICIÓN FARMACÉUTICA QUE COMPRENDE LA COMBINACIÓN DE UN AGENTE INHIBIDOR DE LA ENZIMA HMG-CoA REDUCTASA Y UN AGENTE INHIBIDOR DE LA ENZIMA LIPASA GASTROINTESTINAL
CL2025001949A1 (es) Formulaciones líquidas orales de netupitant y palonosetrón

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees