NO20071549L - Nye benzofuserte heteroalrylsulfamidderivater, anvendelige som anti-krampemidler - Google Patents
Nye benzofuserte heteroalrylsulfamidderivater, anvendelige som anti-krampemidlerInfo
- Publication number
- NO20071549L NO20071549L NO20071549A NO20071549A NO20071549L NO 20071549 L NO20071549 L NO 20071549L NO 20071549 A NO20071549 A NO 20071549A NO 20071549 A NO20071549 A NO 20071549A NO 20071549 L NO20071549 L NO 20071549L
- Authority
- NO
- Norway
- Prior art keywords
- benzofused
- derivatives
- new
- heteroalrylsulfamide
- anticonvulsants
- Prior art date
Links
- 229940125681 anticonvulsant agent Drugs 0.000 title 1
- 239000001961 anticonvulsive agent Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/06—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60413404P | 2004-08-24 | 2004-08-24 | |
| PCT/US2005/029814 WO2006023861A1 (en) | 2004-08-24 | 2005-08-22 | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20071549L true NO20071549L (no) | 2007-05-15 |
Family
ID=35134694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20071549A NO20071549L (no) | 2004-08-24 | 2007-03-23 | Nye benzofuserte heteroalrylsulfamidderivater, anvendelige som anti-krampemidler |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20060047001A1 (es) |
| EP (1) | EP1794143B8 (es) |
| JP (1) | JP4912312B2 (es) |
| KR (1) | KR20070057848A (es) |
| CN (1) | CN101090896B (es) |
| AR (1) | AR050530A1 (es) |
| AT (1) | ATE400565T1 (es) |
| AU (1) | AU2005277134A1 (es) |
| BR (1) | BRPI0514278A (es) |
| CA (1) | CA2578407A1 (es) |
| CR (1) | CR9014A (es) |
| DE (1) | DE602005008084D1 (es) |
| EA (1) | EA010977B1 (es) |
| EC (1) | ECSP077275A (es) |
| ES (1) | ES2310366T3 (es) |
| IL (1) | IL181518A0 (es) |
| MX (1) | MX2007002309A (es) |
| MY (1) | MY142329A (es) |
| NI (1) | NI200700056A (es) |
| NO (1) | NO20071549L (es) |
| PE (1) | PE20060500A1 (es) |
| TW (1) | TW200621745A (es) |
| WO (1) | WO2006023861A1 (es) |
| ZA (1) | ZA200702440B (es) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8095589B2 (en) * | 2002-03-07 | 2012-01-10 | Compete, Inc. | Clickstream analysis methods and systems |
| MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| US20060276528A1 (en) * | 2004-08-24 | 2006-12-07 | Abdel-Magid Ahmed F | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents |
| BRPI0610864A2 (pt) * | 2005-05-20 | 2010-08-03 | Janssen Pharmaceutica Nv | processo para preparação de derivados de sulfamida |
| US8937096B2 (en) | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
| AR058389A1 (es) * | 2005-12-19 | 2008-01-30 | Janssen Pharmaceutica Nv | Uso de derivados heterociclicos benzo-fusionados de sulfamida para el tratamiento de la obesidad |
| US8497298B2 (en) | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
| US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
| US8691867B2 (en) * | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
| US20070155823A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
| US20070155824A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for disease modification / epileptogenesis |
| US8716231B2 (en) | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
| US20070191461A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-heteroaryl sulfamide derivatives for the treatment of migraine |
| US20070191474A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine |
| US20070191459A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for Lowering Lipids and Lowering Blood Glucose Levels |
| US20070191451A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-heteroaryl sulfamide derivatives as neuroprotective agents |
| US20070191452A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-heteroaryl sulfamide derivatives for the treatment of pain |
| US20070191453A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-heteroaryl sulfamide derivatives for the treatment of substance abuse and addiction |
| US20070191449A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Depression |
| US20070191460A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Disease Modification / Epileptogenesis |
| US20070191450A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Mania and Bipolar Disorder |
| TW200738669A (en) * | 2006-02-22 | 2007-10-16 | Janssen Pharmaceutica Nv | Crystalline forms of N-(benzo[b]thien-3-ylmethyl)-sulfamide |
| JP2009537635A (ja) | 2006-05-19 | 2009-10-29 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 癲癇の処置のための共同−療法 |
| TW200812574A (en) * | 2006-05-19 | 2008-03-16 | Janssen Pharmaceutica Nv | Co-therapy for the treatment of epilepsy and related disorders |
| US7897636B2 (en) | 2007-08-08 | 2011-03-01 | Janssen Pharmaceutica Nv | Sulfamide derivative useful for the treatment of epilepsy |
| EP2249828A1 (en) * | 2008-01-07 | 2010-11-17 | Janssen Pharmaceutica, N.V. | Preparation of sulfamide derivatives |
| US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
| CN101981019A (zh) * | 2008-03-26 | 2011-02-23 | 詹森药业有限公司 | 用于制备苯并稠合杂芳基氨基磺酸盐的方法和n-((2s)-6-氯-2,3-二氢-1,4-苯并二噁英-2基)甲基-磺酰胺的晶体形式 |
| US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
| PE20110060A1 (es) | 2008-06-23 | 2011-01-31 | Janssen Pharmaceutica Nv | Forma cristalina de (2s)-(-)-n-(6-cloro-2,3-dihidro-benzo[1,4]dioxin-2-ilmetil)-sulfamida |
| US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
| ME02753B (me) * | 2012-06-21 | 2018-01-20 | Eisai R&D Man Co Ltd | Novi derivati indansulfamida |
| CN105399697A (zh) | 2014-09-12 | 2016-03-16 | 苏州旺山旺水生物医药有限公司 | 一种氨基磺酰基类化合物、其制备方法及用途 |
| CN111801096B (zh) | 2018-03-20 | 2024-03-05 | 卫材R&D管理有限公司 | 癫痫治疗剂 |
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| MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| TW200612905A (en) * | 2004-06-16 | 2006-05-01 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| RU2007139543A (ru) * | 2005-04-22 | 2009-05-27 | Вайет (Us) | Производные бензодиоксана и бензодиоксолана и их применение |
| BRPI0610864A2 (pt) * | 2005-05-20 | 2010-08-03 | Janssen Pharmaceutica Nv | processo para preparação de derivados de sulfamida |
| US20070155824A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for disease modification / epileptogenesis |
| JP2009537635A (ja) * | 2006-05-19 | 2009-10-29 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 癲癇の処置のための共同−療法 |
| CA2711466A1 (en) * | 2008-01-07 | 2009-07-16 | Janssen Pharmaceutica N.V. | Process for the preparation of sulfamide derivatives |
| US20090247618A1 (en) * | 2008-03-26 | 2009-10-01 | Ballentine Scott A | Process for preparation of benzo-fused heteroaryl derivatives |
| US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
| PE20110060A1 (es) * | 2008-06-23 | 2011-01-31 | Janssen Pharmaceutica Nv | Forma cristalina de (2s)-(-)-n-(6-cloro-2,3-dihidro-benzo[1,4]dioxin-2-ilmetil)-sulfamida |
| US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
-
2005
- 2005-08-22 PE PE2005000962A patent/PE20060500A1/es not_active Application Discontinuation
- 2005-08-22 CA CA002578407A patent/CA2578407A1/en not_active Abandoned
- 2005-08-22 KR KR1020077006423A patent/KR20070057848A/ko not_active Withdrawn
- 2005-08-22 ES ES05786700T patent/ES2310366T3/es not_active Expired - Lifetime
- 2005-08-22 CN CN2005800355402A patent/CN101090896B/zh not_active Expired - Fee Related
- 2005-08-22 BR BRPI0514278-4A patent/BRPI0514278A/pt not_active IP Right Cessation
- 2005-08-22 MX MX2007002309A patent/MX2007002309A/es unknown
- 2005-08-22 DE DE602005008084T patent/DE602005008084D1/de not_active Expired - Lifetime
- 2005-08-22 EP EP05786700A patent/EP1794143B8/en not_active Expired - Lifetime
- 2005-08-22 MY MYPI20053930A patent/MY142329A/en unknown
- 2005-08-22 WO PCT/US2005/029814 patent/WO2006023861A1/en not_active Ceased
- 2005-08-22 AT AT05786700T patent/ATE400565T1/de not_active IP Right Cessation
- 2005-08-22 AU AU2005277134A patent/AU2005277134A1/en not_active Abandoned
- 2005-08-22 US US11/209,122 patent/US20060047001A1/en not_active Abandoned
- 2005-08-22 JP JP2007530018A patent/JP4912312B2/ja not_active Expired - Fee Related
- 2005-08-22 EA EA200700489A patent/EA010977B1/ru not_active IP Right Cessation
- 2005-08-23 TW TW094128663A patent/TW200621745A/zh unknown
- 2005-08-23 AR ARP050103535A patent/AR050530A1/es not_active Application Discontinuation
-
2007
- 2007-02-22 IL IL181518A patent/IL181518A0/en unknown
- 2007-02-23 NI NI200700056A patent/NI200700056A/es unknown
- 2007-02-26 EC EC2007007275A patent/ECSP077275A/es unknown
- 2007-03-23 ZA ZA200702440A patent/ZA200702440B/xx unknown
- 2007-03-23 NO NO20071549A patent/NO20071549L/no not_active Application Discontinuation
- 2007-03-23 CR CR9014A patent/CR9014A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0514278A (pt) | 2008-06-10 |
| US20060047001A1 (en) | 2006-03-02 |
| AU2005277134A1 (en) | 2006-03-02 |
| PE20060500A1 (es) | 2006-07-13 |
| JP2008510813A (ja) | 2008-04-10 |
| ES2310366T3 (es) | 2009-01-01 |
| EP1794143A1 (en) | 2007-06-13 |
| DE602005008084D1 (de) | 2008-08-21 |
| CA2578407A1 (en) | 2006-03-02 |
| JP4912312B2 (ja) | 2012-04-11 |
| CN101090896B (zh) | 2011-10-26 |
| IL181518A0 (en) | 2007-07-04 |
| KR20070057848A (ko) | 2007-06-07 |
| MY142329A (en) | 2010-11-15 |
| CN101090896A (zh) | 2007-12-19 |
| TW200621745A (en) | 2006-07-01 |
| ATE400565T1 (de) | 2008-07-15 |
| WO2006023861A1 (en) | 2006-03-02 |
| HK1105411A1 (en) | 2008-02-15 |
| CR9014A (es) | 2009-01-16 |
| EP1794143B1 (en) | 2008-07-09 |
| EA200700489A1 (ru) | 2007-10-26 |
| ZA200702440B (en) | 2009-01-28 |
| MX2007002309A (es) | 2007-10-08 |
| ECSP077275A (es) | 2007-03-29 |
| EP1794143B8 (en) | 2008-12-24 |
| NI200700056A (es) | 2008-02-04 |
| AR050530A1 (es) | 2006-11-01 |
| EA010977B1 (ru) | 2008-12-30 |
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