NO20071930L - t4Methods and compositions for the treatment of hyperlipidemia. - Google Patents

t4Methods and compositions for the treatment of hyperlipidemia.

Info

Publication number
NO20071930L
NO20071930L NO20071930A NO20071930A NO20071930L NO 20071930 L NO20071930 L NO 20071930L NO 20071930 A NO20071930 A NO 20071930A NO 20071930 A NO20071930 A NO 20071930A NO 20071930 L NO20071930 L NO 20071930L
Authority
NO
Norway
Prior art keywords
hyperlipidemia
berberine
methods
compositions
compound
Prior art date
Application number
NO20071930A
Other languages
Norwegian (no)
Inventor
Jian-Dong Jiang
Wei-Jia Kong
Li-Xun Zhao
Dan-Qing Song
Jing Wei
Original Assignee
Inst Medicinal Biotechnology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Medicinal Biotechnology filed Critical Inst Medicinal Biotechnology
Publication of NO20071930L publication Critical patent/NO20071930L/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Metoder og sammensetninger inneholdende en berberinforbindelse eller en berberinrelatert eller derivatisert forbindelse er tilveiebrakt for å forebygge eller behandle hyperlipidemi, forhøyet kolesterol og/eller hjerte/karsykdommer i pattedyrpasienter. Fremgangsmåtene og sammensetningene ifølge den foreliggende oppfinnelsen er effektive til å forebygge og behandle aterosklerose, koronar arteriesykdom, angina pektoris, karotid arteriesykdom, slag, cerebral arteriosklerose, høyt blodtrykk, myokardialt infarkt, cerebralt infarkt, restenose etter ballongangioplasti, tilbakevendende klaudikasjon, dyslipidemi, postprandial lipidemi eller xantom. Det er tilveiebrakt ytterligere sammensetninger og fremgangsmåter som anvender en berberinforbindelse eller berberinrelatert eller derivatisert forbindelse i kombinasjon med et annet antihyperlipidemisk middel eller et annet terapeutisk middel for å gi en mer effektiv behandling av hyperlipidemi og/eller en hjerte/karsykdom og/eller dobbeltaktive terapeutiske metoder og formuleringer som kan brukes for å forebygge eller redusere hyperlipidemi eller ett eller flere kausale eller relaterte symptomer eller tilstander som er assosiert med hyperlipidemi hos pattedyrpasienter.Methods and compositions containing a berberine compound or a berberine-related or derivatized compound are provided to prevent or treat hyperlipidemia, elevated cholesterol and / or cardiovascular disease in mammalian patients. The methods and compositions of the present invention are effective in preventing and treating atherosclerosis, coronary artery disease, angina pectoris, carotid artery disease, stroke, cerebral arteriosclerosis, high blood pressure, myocardial infarction, cerebral ductal plaque anatomy, restenosis after balloon angiography, restenosis after balloon or xanthome. Additional compositions and methods are provided employing a berberine compound or berberine-related or derivatized compound in combination with another antihyperlipidemic agent or other therapeutic agent to provide a more effective treatment of hyperlipidemia and / or cardiovascular disease and / or dual-active therapeutic methods. and formulations that can be used to prevent or reduce hyperlipidemia or one or more causal or related symptoms or conditions associated with hyperlipidemia in mammalian patients.

NO20071930A 2004-09-17 2007-04-16 t4Methods and compositions for the treatment of hyperlipidemia. NO20071930L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN200410078150 2004-09-17
CN200410095066XA CN1759834B (en) 2004-09-17 2004-11-23 Use of berberine or its combination with simvastatin in the preparation of products for preventing or treating diseases or symptoms related to blood lipids
PCT/CN2005/001489 WO2006029577A1 (en) 2004-09-17 2005-09-19 Methods and compositions for the treatment of hyperlipidemia

Publications (1)

Publication Number Publication Date
NO20071930L true NO20071930L (en) 2007-06-12

Family

ID=36059710

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071930A NO20071930L (en) 2004-09-17 2007-04-16 t4Methods and compositions for the treatment of hyperlipidemia.

Country Status (14)

Country Link
US (3) US20060223838A1 (en)
EP (2) EP2361625A1 (en)
JP (1) JP2008513382A (en)
KR (1) KR20070095279A (en)
CN (1) CN1759834B (en)
AU (1) AU2005284528A1 (en)
BR (1) BRPI0515393A (en)
CA (1) CA2620208A1 (en)
IL (1) IL181896A0 (en)
MX (1) MX2007003023A (en)
NO (1) NO20071930L (en)
NZ (1) NZ554475A (en)
RU (1) RU2007114290A (en)
WO (1) WO2006029577A1 (en)

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