NO20071967L - Imidazo-benzodiazepinderivater - Google Patents
Imidazo-benzodiazepinderivaterInfo
- Publication number
- NO20071967L NO20071967L NO20071967A NO20071967A NO20071967L NO 20071967 L NO20071967 L NO 20071967L NO 20071967 A NO20071967 A NO 20071967A NO 20071967 A NO20071967 A NO 20071967A NO 20071967 L NO20071967 L NO 20071967L
- Authority
- NO
- Norway
- Prior art keywords
- imidazo
- benzodiazepine
- cognitive
- triazolo
- gaba
- Prior art date
Links
- KLNFAMGHSZQYHR-UHFFFAOYSA-N imidazo[4,5-i][1,2]benzodiazepine Chemical compound C1=CC=NN=C2C3=NC=NC3=CC=C21 KLNFAMGHSZQYHR-UHFFFAOYSA-N 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 239000002475 cognitive enhancer Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960003692 gamma aminobutyric acid Drugs 0.000 abstract 1
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 abstract 1
- MEYXEJCDZRDIFZ-UHFFFAOYSA-N imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepine Chemical class C=1N2N=CN=C2C2=CC=CC=C2N2CN=CC2=1 MEYXEJCDZRDIFZ-UHFFFAOYSA-N 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04105169 | 2004-10-20 | ||
| PCT/EP2005/010908 WO2006045430A1 (en) | 2004-10-20 | 2005-10-11 | Imidazo-benzodiazepine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20071967L true NO20071967L (no) | 2007-05-14 |
Family
ID=36035782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20071967A NO20071967L (no) | 2004-10-20 | 2007-04-17 | Imidazo-benzodiazepinderivater |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7514426B2 (pt) |
| EP (1) | EP1805184B1 (pt) |
| JP (1) | JP4783375B2 (pt) |
| KR (1) | KR100923399B1 (pt) |
| CN (1) | CN101044145B (pt) |
| AR (1) | AR051395A1 (pt) |
| AU (1) | AU2005299032B2 (pt) |
| BR (1) | BRPI0519991A2 (pt) |
| CA (1) | CA2584259C (pt) |
| ES (1) | ES2399439T3 (pt) |
| IL (1) | IL182585A0 (pt) |
| MX (1) | MX2007004639A (pt) |
| NO (1) | NO20071967L (pt) |
| NZ (1) | NZ554439A (pt) |
| RU (1) | RU2007112940A (pt) |
| TW (1) | TWI303247B (pt) |
| WO (1) | WO2006045430A1 (pt) |
| ZA (1) | ZA200703172B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1828194B1 (en) * | 2004-12-14 | 2008-05-28 | F. Hoffmann-Roche AG | Tetracyclic imidazo-benzodiazepines as gaba receptors modulators |
| BRPI0617204A2 (pt) * | 2005-10-11 | 2011-07-19 | Hoffmann La Roche | derivados de imidazo benzodiazepina |
| FR2913886B1 (fr) | 2007-03-22 | 2012-03-02 | Guerbet Sa | Utilisation de nanoparticules metalliques dans le diagnostique de la maladie d'alzheimer |
| EP2298296A1 (en) | 2009-08-25 | 2011-03-23 | CNRS Centre National De La Recherche Scientifique | Composition and method for treating cognitive impairments in down syndrome subjects |
| WO2011153377A2 (en) * | 2010-06-03 | 2011-12-08 | The Regents Of The University Of California | Methods and compositions for treating a subject for central nervous system (cns) injury |
| MX341471B (es) * | 2010-11-05 | 2016-08-22 | Hoffmann La Roche | Uso de compuestos farmaceuticos activos para el tratamiento de estados patologicos del sistema nervioso central. |
| EP2457569A1 (en) | 2010-11-05 | 2012-05-30 | F. Hoffmann-La Roche AG | Use of active pharmaceutical compounds for the treatment of central nervous system conditions |
| EP3034079B1 (en) | 2010-11-15 | 2018-01-10 | Agenebio, Inc. | Pyridazine derivatives, compositions and methods for treating cognitive impairment |
| US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
| NZ760341A (en) * | 2013-12-20 | 2021-12-24 | Agenebio Inc | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| MX392119B (es) | 2015-06-19 | 2025-03-11 | Agenebio Inc | Derivados de benzodiazepina, composiciones y metodos para tratar deterioro cognitivo |
| US11505555B2 (en) | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US20180170941A1 (en) * | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| BR112020004116A2 (pt) * | 2017-08-28 | 2020-09-01 | University Of Maryland, Baltimore | novos moduladores do receptor de ácido gama aminobutírico tipo a para distúrbios de humor |
| CN112601749B (zh) | 2018-06-19 | 2024-03-26 | 艾吉因生物股份有限公司 | 用于治疗认知损害的苯并二氮杂环庚三烯衍生物，组合物和方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1143728A (en) | 1979-10-04 | 1983-03-29 | Max Gerecke | Imidazodiazepine derivatives |
| CA1174673A (en) * | 1981-02-27 | 1984-09-18 | Walter Hunkeler | Imidazodiazepines |
| IL74070A (en) | 1984-01-19 | 1988-12-30 | Hoffmann La Roche | Imidazodiazepine derivatives,their manufacture and pharmaceutical compositions containing them |
| DK174086D0 (da) | 1986-04-16 | 1986-04-16 | Ferrosan As | Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme |
| ZA881538B (en) * | 1987-03-10 | 1988-09-12 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Imidazodiazepine derivatives |
| US4897392A (en) | 1989-07-03 | 1990-01-30 | Hoechst-Roussel Pharmaceuticals, Inc. | 4H-indolo(1,2-d)(1,2,4)triazolo(4,3-A)(1,4)benzodiazepines |
| TW201311B (pt) * | 1991-06-17 | 1993-03-01 | Hoffmann La Roche | |
| TWI239333B (en) * | 2000-11-16 | 2005-09-11 | Hoffmann La Roche | Benzodiazepine derivatives as GABA A receptor modulators |
| US6686352B2 (en) * | 2001-05-18 | 2004-02-03 | Hoffmann-La Roche Inc. | Substituted imidazo [1,5-a] pyrimido [5,4-d] [1] benzazepine derivatives |
-
2005
- 2005-10-11 MX MX2007004639A patent/MX2007004639A/es active IP Right Grant
- 2005-10-11 NZ NZ554439A patent/NZ554439A/en not_active IP Right Cessation
- 2005-10-11 RU RU2007112940/04A patent/RU2007112940A/ru not_active Application Discontinuation
- 2005-10-11 AU AU2005299032A patent/AU2005299032B2/en not_active Ceased
- 2005-10-11 ES ES05796938T patent/ES2399439T3/es not_active Expired - Lifetime
- 2005-10-11 WO PCT/EP2005/010908 patent/WO2006045430A1/en not_active Ceased
- 2005-10-11 BR BRPI0519991-3A patent/BRPI0519991A2/pt not_active Application Discontinuation
- 2005-10-11 CN CN2005800359992A patent/CN101044145B/zh not_active Expired - Fee Related
- 2005-10-11 JP JP2007537162A patent/JP4783375B2/ja not_active Expired - Fee Related
- 2005-10-11 EP EP05796938A patent/EP1805184B1/en not_active Expired - Lifetime
- 2005-10-11 CA CA2584259A patent/CA2584259C/en not_active Expired - Lifetime
- 2005-10-11 KR KR1020077008928A patent/KR100923399B1/ko not_active Expired - Fee Related
- 2005-10-17 US US11/252,025 patent/US7514426B2/en active Active
- 2005-10-17 TW TW094136208A patent/TWI303247B/zh not_active IP Right Cessation
- 2005-10-18 AR ARP050104348A patent/AR051395A1/es unknown
-
2007
- 2007-04-16 IL IL182585A patent/IL182585A0/en not_active IP Right Cessation
- 2007-04-17 NO NO20071967A patent/NO20071967L/no not_active Application Discontinuation
- 2007-04-17 ZA ZA200703172A patent/ZA200703172B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006045430A1 (en) | 2006-05-04 |
| CN101044145A (zh) | 2007-09-26 |
| CA2584259C (en) | 2013-04-02 |
| EP1805184B1 (en) | 2013-01-09 |
| NZ554439A (en) | 2009-09-25 |
| CN101044145B (zh) | 2010-06-16 |
| TW200630372A (en) | 2006-09-01 |
| US7514426B2 (en) | 2009-04-07 |
| US20060084642A1 (en) | 2006-04-20 |
| ZA200703172B (en) | 2008-08-27 |
| KR100923399B1 (ko) | 2009-10-23 |
| AU2005299032B2 (en) | 2011-11-17 |
| BRPI0519991A2 (pt) | 2009-04-07 |
| AU2005299032A1 (en) | 2006-05-04 |
| TWI303247B (en) | 2008-11-21 |
| IL182585A0 (en) | 2007-07-24 |
| JP4783375B2 (ja) | 2011-09-28 |
| RU2007112940A (ru) | 2008-11-27 |
| JP2008517011A (ja) | 2008-05-22 |
| ES2399439T3 (es) | 2013-04-01 |
| EP1805184A1 (en) | 2007-07-11 |
| AR051395A1 (es) | 2007-01-10 |
| CA2584259A1 (en) | 2006-05-04 |
| KR20070054731A (ko) | 2007-05-29 |
| MX2007004639A (es) | 2007-06-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |