NO20072259L - Heteroaryltiazoler og deres anvendelse som P13K-inhibitorer - Google Patents

Heteroaryltiazoler og deres anvendelse som P13K-inhibitorer

Info

Publication number
NO20072259L
NO20072259L NO20072259A NO20072259A NO20072259L NO 20072259 L NO20072259 L NO 20072259L NO 20072259 A NO20072259 A NO 20072259A NO 20072259 A NO20072259 A NO 20072259A NO 20072259 L NO20072259 L NO 20072259L
Authority
NO
Norway
Prior art keywords
heteroarylthiazoles
inhibitors
therapy
manufacture
processes
Prior art date
Application number
NO20072259A
Other languages
English (en)
Norwegian (no)
Inventor
Joakim Larsson
Peter Storm
Grigorios Nikitidis
John Peter Bailey
Malena Bengtsson
Edward Jolyon Griffen
Jean-Claude Arnould
Thomas Geoffrey Colerick Bird
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20072259L publication Critical patent/NO20072259L/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
NO20072259A 2004-11-09 2007-04-30 Heteroaryltiazoler og deres anvendelse som P13K-inhibitorer NO20072259L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0402735A SE0402735D0 (sv) 2004-11-09 2004-11-09 Novel compounds
PCT/GB2005/004268 WO2006051270A1 (en) 2004-11-09 2005-11-07 5-heteroaryl thiazoles and their use as p13k inhibitors

Publications (1)

Publication Number Publication Date
NO20072259L true NO20072259L (no) 2007-06-06

Family

ID=33488202

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072259A NO20072259L (no) 2004-11-09 2007-04-30 Heteroaryltiazoler og deres anvendelse som P13K-inhibitorer

Country Status (20)

Country Link
US (1) US7868188B2 (de)
EP (1) EP1841763B1 (de)
JP (1) JP2008519021A (de)
KR (1) KR20070085837A (de)
CN (1) CN101098869A (de)
AR (1) AR052232A1 (de)
AT (1) ATE472546T1 (de)
AU (1) AU2005303566A1 (de)
BR (1) BRPI0517634A (de)
CA (1) CA2585310A1 (de)
DE (1) DE602005022116D1 (de)
ES (1) ES2346333T3 (de)
IL (1) IL182726A0 (de)
MX (1) MX2007005546A (de)
NO (1) NO20072259L (de)
SE (1) SE0402735D0 (de)
TW (1) TW200621762A (de)
UY (1) UY29199A1 (de)
WO (1) WO2006051270A1 (de)
ZA (1) ZA200703714B (de)

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AR044519A1 (es) 2003-05-02 2005-09-14 Novartis Ag Derivados de piridin-tiazol amina y de pirimidin-tiazol amina
US7786137B2 (en) * 2005-05-10 2010-08-31 Vertex Pharmaceuticals Incorporated Bicyclic derivatives as modulators of ion channels
AU2006251157B2 (en) 2005-05-24 2011-09-01 Merck Serono Sa Thiazole derivatives and use thereof
CN101421265A (zh) 2006-01-18 2009-04-29 安姆根有限公司 作为蛋白激酶b(pkb)抑制剂的噻唑化合物
AU2007206860A1 (en) * 2006-01-23 2007-07-26 Laboratoires Serono S.A. Thiazole derivatives and use thereof
CA2640090A1 (en) 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Substituted aromatic compounds for inflammation and immune-related uses
EP2007393B1 (de) * 2006-04-07 2013-08-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Thiazol- und thiophen-analoga sowie ihre verwendung zur behandlung von autoimmunerkrankungen und karzinomen
WO2007129044A1 (en) * 2006-05-03 2007-11-15 Astrazeneca Ab Thiazole derivatives and their use as anti-tumour agents
ATE414281T1 (de) 2006-08-03 2008-11-15 Cellzome Ag Verfahren zur identifizierung von molekülen die mit pi3k interagieren und verfahren zur reinigung von pi3k
AU2007290359B2 (en) * 2006-09-01 2012-09-20 Vertex Pharmaceuticals Incorporated 5- (2-furyl)-1, 3-thiazole derivatives useful as inhibitors of phosphatidylinositol 3-kinase
GB0620059D0 (en) * 2006-10-10 2006-11-22 Ucb Sa Therapeutic agents
GB0620818D0 (en) * 2006-10-19 2006-11-29 Ucb Sa Therapeutic agents
US8263585B2 (en) 2007-05-04 2012-09-11 Novartis Ag Organic compounds
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