NO20072332L - Lerkanidipinkapsler - Google Patents

Lerkanidipinkapsler

Info

Publication number
NO20072332L
NO20072332L NO20072332A NO20072332A NO20072332L NO 20072332 L NO20072332 L NO 20072332L NO 20072332 A NO20072332 A NO 20072332A NO 20072332 A NO20072332 A NO 20072332A NO 20072332 L NO20072332 L NO 20072332L
Authority
NO
Norway
Prior art keywords
fatty acid
acid ester
ester
mixture
polyethylene glycol
Prior art date
Application number
NO20072332A
Other languages
English (en)
Inventor
Amedeo Leonardi
Fabio Berlati
Lino Pontello
Original Assignee
Recordati Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Ireland Ltd filed Critical Recordati Ireland Ltd
Publication of NO20072332L publication Critical patent/NO20072332L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

En modifisert frigivende farmasøytisk sammensetning omfatter lerkanidipin oppløst i en voksaktig substans omfattende en polyalkoholfettsyreester, hvor løsningen er innlemmet i en farmasøytisk akseptabel kapsel. Fortrinnsvis er polyalkoholfettsyreesteren en polyetylenglykolester, en polypropylenglykolester, et fettsyreglyserid eller en blanding av to eller flere derav. Mest foretrukket er polyalkoholfettsyreesteren en blanding av mono-, di- og triglyserider og polyetylenglykolmono- og -diestere. Oral administrasjon av de modifiserte frigivende farmasøytiske sammensetninger til en pasient har vist seg å resultere i en midlere plasmakonsentrasjon av lerkanidipin på mer enn 0,5 ng/ml i 24 timer etter administrasjonen. ?? ?? ?? ??
NO20072332A 2004-10-05 2007-05-04 Lerkanidipinkapsler NO20072332L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61591904P 2004-10-05 2004-10-05
US65679205P 2005-02-25 2005-02-25
PCT/EP2005/010813 WO2006037650A1 (en) 2004-10-05 2005-10-05 Lercanidipine capsules

Publications (1)

Publication Number Publication Date
NO20072332L true NO20072332L (no) 2007-05-04

Family

ID=35455723

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072332A NO20072332L (no) 2004-10-05 2007-05-04 Lerkanidipinkapsler

Country Status (16)

Country Link
US (1) US20060073200A1 (no)
EP (1) EP1807059A1 (no)
JP (1) JP2008515839A (no)
KR (1) KR20070058632A (no)
AR (1) AR051742A1 (no)
AU (1) AU2005291354A1 (no)
BR (1) BRPI0516179A (no)
CA (1) CA2580525A1 (no)
EA (1) EA200700735A1 (no)
IL (1) IL181938A0 (no)
MX (1) MX2007004105A (no)
NO (1) NO20072332L (no)
PE (1) PE20060946A1 (no)
TW (1) TW200616681A (no)
UY (1) UY29150A1 (no)
WO (1) WO2006037650A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR053023A1 (es) * 2005-02-25 2007-04-18 Recordati Ireland Ltd Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen
AR052918A1 (es) 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
WO2008040367A1 (en) * 2006-08-01 2008-04-10 Union Quimico-Farmaceutica S.A. Lercanidipine hydrobromide, a process for its preparation, crystalline forms and compositions thereof
MX2009002166A (es) 2006-08-31 2009-03-12 Eurand Inc Sistema de distribucion de farmacos, que comprenden soluciones solidas de farmacos debilmente basicos.
US20080175872A1 (en) * 2006-09-28 2008-07-24 Osmotica Corp. Controlled Release Dosage Form Containing Lercanidipine and a Performance-enhancing Acid
DE102010005124A1 (de) * 2010-01-19 2012-03-01 Stada Arzneimittel Ag Feste pharmazeutische Zusammensetzung umfassend Lercanidipin

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters
HU197201B (en) * 1985-10-01 1989-03-28 Sandoz Ag Process for producing oral pharmaceutical compositions of controlled solubility of the active components
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat
US5696139A (en) * 1995-05-12 1997-12-09 Recordati S.A., Chemical And Pharmaceutical Company Use of S-enantiomers of 1,4-dihydropyridine derivatives for treating heart failure
US5912351A (en) * 1995-05-12 1999-06-15 Recordati, S.A. Chemical And Pharmaceutical Company Anhydrous 1,4-Dihydropyridines and salts thereof
WO1999021534A1 (en) * 1997-10-27 1999-05-06 Merck Patent Gmbh Solid state solutions and dispersions of poorly water soluble drugs
US20030235595A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent
GB2355656B (en) * 1999-08-17 2004-04-07 Galena As Pharmaceutical compositions for oral and topical administration
US6852737B2 (en) * 2001-08-06 2005-02-08 Recordati Ireland Limited Crude and crystalline forms of lercanidipine hydrochloride
US20030069285A1 (en) * 2001-08-06 2003-04-10 Recordati Ireland Limited Novel solvate and crystalline forms of lercanidipine hydrochloride

Also Published As

Publication number Publication date
EP1807059A1 (en) 2007-07-18
CA2580525A1 (en) 2006-04-13
PE20060946A1 (es) 2006-10-02
KR20070058632A (ko) 2007-06-08
UY29150A1 (es) 2005-11-30
EA200700735A1 (ru) 2007-10-26
JP2008515839A (ja) 2008-05-15
BRPI0516179A (pt) 2008-08-26
AR051742A1 (es) 2007-02-07
TW200616681A (en) 2006-06-01
WO2006037650A1 (en) 2006-04-13
AU2005291354A1 (en) 2006-04-13
MX2007004105A (es) 2007-06-15
US20060073200A1 (en) 2006-04-06
IL181938A0 (en) 2007-07-04

Similar Documents

Publication Publication Date Title
DE50104138D1 (de) Injizierbare pharmazeutische zusammensetzung zur systemischen verabreichung pharmakologisch aktiver wirkstoffe enthaltend mittelkettige triglyceride
CA2556993A1 (en) Pimecrolimus foam composition containing hexylene glycol, optionally oleyl alcohol, dimethylisosorbide and/or medium chain triglycerides
WO2002039983A3 (en) Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
DK1152755T3 (da) Essentielle fedtsyrer til forebyggelse af cardiovaskulære tilfælde
PE20030399A1 (es) Formas de administracion de propiverina o sus sales farmaceuticamente aceptables con liberacion prolongada de la sustancia activa
DK0752855T3 (da) Anvendelse af fedtsyreestere som bioadhæsive substanser
AR037490A1 (es) Composiciones farmaceuticas solidas, proceso para su preparacion, kit para el tratamiento de la obesidad y uso de dichas composiciones en la elaboracion de medicamentos
NO20000465L (no) Farmasøytisk preparat i form av en selvemulgerende formulering for lipofile forbindelser
EP0852494A2 (en) Peripherally active anti-hyperalgesic opiates
HUP0303881A3 (en) Pharmaceutical compositions containing fatty alcohols and fatty acid esters useful for treatment of inflammation
EE03425B1 (et) Lihtsa koostise ja kõrge biosaadavusega tsüklosporiini preparaadid suu kaudu manustamiseks ja nende valmistamismeetod
BR0209320A (pt) ésteres de uridina farmaceuticamente ativos
MXPA05010607A (es) Composiciones de distribucion de farmacos de ester de alfa-hidroxiacido y metodos de uso.
JP2020535162A (ja) 増強された送達のエピネフリン及びプロドラッグ組成物
ATE301989T1 (de) Orale pharmazeutische zusammensetzung mit einem wirkstoff, der bei seiner ersten darmpassage starken wirkungen ausgesetzt werden kann
GEP20053455B (en) Pharmaceutical Preparations
ES2971854T3 (es) Preparación de absorción transdérmica que contiene oxibutinina
ATE253354T1 (de) Kapseln mit loratadin und pseudoephedrin enthaltenden zusammensetzungen
TW200616681A (en) Lercanidipine capsules
WO2005025488A3 (en) Methods for the controlled delivery of pharmacologically active compounds
RU2015128028A (ru) Длинноцепочечные липосбалансированные сложные эфиры тестостерона для пероральной доставки
ES2172179T3 (es) Composiciones farmaceuticas de liberacion controlada que contienen tiagabina.
WO2010019279A8 (en) Pharmaceutical compositions configured to deter dosage form splitting
IT1293835B1 (it) Composizioni farmaceutiche orali in forma solida a cessione modulata contenenti nicorandil e procedimento per la loro preparazione
ATE322896T1 (de) Verbesserte pharmazeutische zusammensetzung mit einem ppar-alpha-mittel und verfahren zu ihrer herstellung

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application