NO20074025L - Konjugater for dobbel billeddannelse og radiokjemoterapi:sammensetninger, fremstilling og anvendelse - Google Patents

Konjugater for dobbel billeddannelse og radiokjemoterapi:sammensetninger, fremstilling og anvendelse

Info

Publication number
NO20074025L
NO20074025L NO20074025A NO20074025A NO20074025L NO 20074025 L NO20074025 L NO 20074025L NO 20074025 A NO20074025 A NO 20074025A NO 20074025 A NO20074025 A NO 20074025A NO 20074025 L NO20074025 L NO 20074025L
Authority
NO
Norway
Prior art keywords
dual imaging
radiochemistry
conjugates
compositions
preparation
Prior art date
Application number
NO20074025A
Other languages
English (en)
Norwegian (no)
Inventor
E Edmund Kim
David J Yang
Dongfang Yu
Mithu Chanda
Ali Azhdarinia
Changsok Oh
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Publication of NO20074025L publication Critical patent/NO20074025L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549Sugars, nucleosides, nucleotides or nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0491Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/00272-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20074025A 2005-01-05 2007-08-03 Konjugater for dobbel billeddannelse og radiokjemoterapi:sammensetninger, fremstilling og anvendelse NO20074025L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64155905P 2005-01-05 2005-01-05
PCT/US2006/000269 WO2006074272A2 (en) 2005-01-05 2006-01-05 Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications

Publications (1)

Publication Number Publication Date
NO20074025L true NO20074025L (no) 2007-09-27

Family

ID=36648161

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074025A NO20074025L (no) 2005-01-05 2007-08-03 Konjugater for dobbel billeddannelse og radiokjemoterapi:sammensetninger, fremstilling og anvendelse

Country Status (11)

Country Link
US (2) US8147805B2 (pt)
EP (1) EP1846042A2 (pt)
JP (1) JP2008531755A (pt)
KR (1) KR101313712B1 (pt)
CN (1) CN101137398B (pt)
AU (2) AU2006204045B2 (pt)
BR (1) BRPI0606395A2 (pt)
CA (1) CA2593256A1 (pt)
IL (1) IL184415A0 (pt)
NO (1) NO20074025L (pt)
WO (1) WO2006074272A2 (pt)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067111B1 (en) * 1999-10-25 2006-06-27 Board Of Regents, University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
JP4868698B2 (ja) 2001-05-02 2012-02-01 パーデュー・リサーチ・ファウンデーション マクロファージが仲介する疾患の治療および診断
US8043603B2 (en) 2002-02-07 2011-10-25 Endocyte, Inc. Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
US8043602B2 (en) 2002-02-07 2011-10-25 Endocyte, Inc. Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
ATE412897T1 (de) 2003-05-30 2008-11-15 Purdue Research Foundation Diagnoseverfahren für atherosklerose
US9050378B2 (en) * 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
ITMI20040928A1 (it) 2004-05-07 2004-08-07 Uni Di Bologna Dipartiment O D Procedura per la preparazione di coniugati della doxorubicina con l'albumina umana lattosaminata
CN101128152A (zh) * 2004-12-23 2008-02-20 普渡研究基金会 发射正电子段层成像方法
US8703097B2 (en) * 2005-02-11 2014-04-22 University Health Network Compositions and method for multimodal imaging
US9820986B2 (en) * 2005-03-04 2017-11-21 Taiwan Hopaz Chems, Mfg. Co., Ltd. Glycopeptide compositions
WO2007006041A2 (en) 2005-07-05 2007-01-11 Purdue Research Foundation Imaging and therapeutic method using monocytes
ITMI20051743A1 (it) * 2005-09-20 2007-03-21 Uni Di Bologna Dipartimento Di Patologia Spa Uso di coniugati della doxorubicina con albumina lattosaminata
WO2007038346A2 (en) * 2005-09-23 2007-04-05 Purdue Research Foundation Multiphoton in vivo flow cytometry method and device
WO2007126730A1 (en) * 2006-03-29 2007-11-08 Isotherapeautics Group Llc Radionuclide therapy for urinary bladder cancer
WO2007120153A1 (en) * 2006-04-19 2007-10-25 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
US10925977B2 (en) * 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
EP2087337A4 (en) 2006-11-03 2010-09-08 Purdue Research Foundation METHOD AND DEVICE FOR EX-VIVO FLOW CYTOMETRY
WO2008064040A2 (en) * 2006-11-22 2008-05-29 The Board Of Regents Of The University Of Texas System Methods and compositions using chelator-antibody conjugates
EP2109466B1 (en) * 2007-02-07 2014-11-12 Purdue Research Foundation Positron emission tomography imaging method
MX340566B (es) * 2007-03-27 2016-07-14 Radiomedix Inc Composiciones para formacion de imagen objetivo y terapia.
WO2008148001A2 (en) * 2007-05-25 2008-12-04 Purdue Research Foundation Method of imaging localized infections
US20120277409A1 (en) * 2007-06-04 2012-11-01 Board Of Regents, The University Of Texas System Metal-polysaccharide conjugates: compositions, synthesis and methods for cancer therapy
GB0725070D0 (en) * 2007-12-21 2008-01-30 Iopharma Technologies Ab Product
DE102008045937B4 (de) * 2008-04-11 2017-01-26 Johannes-Gutenberg-Universität Mainz Radiopharmakon aus einem Metallion und einem Markierungsvorläufer und Verwendung des Radiopharmakons
US20090264753A1 (en) * 2008-04-22 2009-10-22 General Electric Company Method & system for multi-modality imaging of sequentially obtained pseudo-steady state data
WO2009137428A2 (en) * 2008-05-05 2009-11-12 Emory University Methods of determining renal function using technetium-99m tricarbonyl-nitrilotriacetic acid
WO2010004464A1 (en) 2008-07-09 2010-01-14 Koninklijke Philips Electronics N.V. Physiological pharmacokinetic analysis for combined molecular mri and dynamic pet imaging
CN102458442B (zh) * 2009-04-08 2016-06-29 加利福尼亚大学董事会 具有受控血清药代动力学的人蛋白支架
JP2011063572A (ja) * 2009-09-18 2011-03-31 Kyushu Univ 診断用造影剤
KR100991716B1 (ko) * 2009-10-22 2010-11-04 경북대학교 산학협력단 광학영상 조영제, 그 용도 및 장치
US8547533B2 (en) 2009-12-28 2013-10-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Composite probes and use thereof in super resolution methods
KR101395085B1 (ko) * 2010-06-11 2014-05-21 국립암센터 종양 및 감시림프절에 특이적인 방사성동위원소 표지된 엽산 결합 인혈청 알부민
CN102218150B (zh) * 2010-08-17 2013-01-30 扬州大学 肝靶向纳米Fe3O4MRI造影剂及制备方法
CN102398026B (zh) * 2010-09-10 2013-10-23 聚和国际股份有限公司 甲壳素修饰的纳米金粒子及其制造方法
CN102558291B (zh) * 2010-12-17 2014-03-12 北京大学人民医院 一种双模分子影像探针
US20140199243A1 (en) * 2011-06-17 2014-07-17 Centre National De La Recherche Scientifique Bifunctional phosphonate chelating agents
CA2843313C (en) 2011-06-20 2018-02-13 Radiomedix Inc. Compositions, methods of synthesis and use of carbohydrate targeted agents
US10307167B2 (en) 2012-12-14 2019-06-04 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10314594B2 (en) 2012-12-14 2019-06-11 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10813630B2 (en) 2011-08-09 2020-10-27 Corquest Medical, Inc. Closure system for atrial wall
AU2012347765B2 (en) * 2011-12-06 2017-05-04 Research Institute At Nationwide Childrens's Hospital Non-ionic, low osmolar contrast agents for delivery of antisense oligonucleotides and treatment of disease
PT2830666T (pt) * 2012-03-26 2020-04-02 Univ Texas Síntese eficiente de conjugados de etilenodicisteína-açúcar para imagiologia e terapia
CN104487098B (zh) * 2012-07-20 2017-12-15 佳能株式会社 光声成像用造影剂
US20140142689A1 (en) 2012-11-21 2014-05-22 Didier De Canniere Device and method of treating heart valve malfunction
JP6359554B2 (ja) * 2012-12-12 2018-07-18 ソルベイ スペシャルティ ポリマーズ イタリー エス.ピー.エー. フッ素化キトサン誘導体
US10035009B2 (en) 2013-04-15 2018-07-31 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for treating pancreatic cancer
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
US9850183B2 (en) 2014-06-27 2017-12-26 Reiley Pharmaceuticals, Inc. Conjugates derived from non-steroidal anti-inflammatory drugs and methods of use thereof in imaging
BE1021191B1 (fr) * 2014-08-29 2015-10-27 Anmi S.A. Kit pour radiomarquage.
US11027030B2 (en) 2014-08-29 2021-06-08 Anmi S.A. Kit for radiolabelling
US10842626B2 (en) 2014-12-09 2020-11-24 Didier De Canniere Intracardiac device to correct mitral regurgitation
US10053478B2 (en) 2015-01-09 2018-08-21 Reiley Pharmaceuticals, Inc. COX-2-targeting, platinum-containing conjugates and their use in the treatment of tumors and cancers
WO2017090047A1 (en) 2015-11-27 2017-06-01 Technology Innovation Momentum Fund (Israel) Limited Partnership Glucosamine and derivatives thereof in imaging
CN108761078A (zh) * 2018-05-19 2018-11-06 复旦大学 胰腺癌基底微绒毛的检测方法和应用
IL271681A (en) 2018-07-18 2020-01-30 Vyripharm Entpr Llc Systems and methods for integrated and comprehensive management of cannabis products
KR20200047322A (ko) 2018-10-26 2020-05-07 전남대학교병원 체내위치확인 시스템
CN114555131A (zh) * 2019-08-19 2022-05-27 纳维迪亚生物制药有限公司 用于消融m2巨噬细胞和髓源性抑制细胞的组合物和相关方法
CN110563859B (zh) * 2019-09-19 2021-07-23 湖北医药学院 抗肝癌药物亚硒酸酯化壳聚糖铜的一锅合成法及应用
CN110981940A (zh) * 2019-11-08 2020-04-10 复旦大学附属肿瘤医院 一种pd-l1结合剂、金属配合物及其使用方法和用途
DE102019135564B4 (de) * 2019-12-20 2022-05-19 Johannes-Gutenberg-Universität Mainz Verbindung für Smart-Drug-Delivery und pharmazeutisches Kit für duale nuklearmedizinisch-cytotoxische Theranostik
CN120550144A (zh) * 2020-12-28 2025-08-29 波士顿科学医学有限公司 具有改善的放射性造影特性的多糖
US20220305146A1 (en) * 2021-03-26 2022-09-29 Vyripharm Enterprises, Inc. Radiopharmaceutical compositions and methods for infectious disease diagnosis and therapy
WO2023201377A2 (en) * 2022-04-15 2023-10-19 The General Hospital Corporation Scission-enhanced nuclear imaging and treatment
CN116655928B (zh) * 2023-04-18 2025-08-29 扬州大学 一种基于半胱氨酸的超分子手性光热剂及其应用

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE465907B (sv) * 1984-11-01 1991-11-18 Nyegaard & Co As Diagnosticeringsmedel innehaallande en paramagnetisk metall
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
US5707604A (en) * 1986-11-18 1998-01-13 Access Pharmaceuticals, Inc. Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
CA1340556C (en) * 1986-12-30 1999-05-25 Komei Washino High molecular compound comprising unit of asialoglyco-protein acceptor-directing compound and unit of chelate-forming compound chemically bonded thereto, and its utilization
US4965392A (en) * 1987-03-26 1990-10-23 Neorx Corporation Chelating compounds for metal-radionuclide labeled proteins
US5364613A (en) * 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
US5116599A (en) * 1989-07-31 1992-05-26 Johns Hopkins Univ. Perfluoro-t-butyl-containing compounds for use in fluorine-19 nmr and/or mri
WO1991016076A1 (en) * 1990-04-17 1991-10-31 Mallinckrodt Medical, Inc. Method and kit for preparing technetium-99m complexes
CA2084315A1 (en) * 1990-06-01 1991-12-02 Institut Fur Diagnostikforschung Gmbh An Der Freien Universitat Berlin Cyclopentadienylcarbonyl 99m tc complexes, process for their production as well as their use in diagnostics
CA2089519C (en) * 1990-08-17 2000-01-11 Kazuhiro Inoue N-acetylcarboxymethylchitosan derivatives and process for preparation thereof
JP2894879B2 (ja) * 1991-10-04 1999-05-24 日本メジフィジックス株式会社 診断用造影剤
WO1994005203A1 (en) * 1992-09-04 1994-03-17 The General Hospital Corporation Biocompatible polymers containing diagnostic or therapeutic moieties
US5605672A (en) 1993-06-09 1997-02-25 The General Hospital Corporation Blood pool imaging composition and method of its use
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
US5955053A (en) * 1996-05-06 1999-09-21 Emory University Metal chelates as pharmaceutical imaging agents, processes of making such and uses thereof
US5986074A (en) * 1996-05-06 1999-11-16 Emory University Metal chelates as pharmaceutical imaging agents, processes of making such and uses thereof
US5900228A (en) * 1996-07-31 1999-05-04 California Institute Of Technology Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye
JP2001519379A (ja) * 1997-10-09 2001-10-23 ペリオ、プロダクツ、リミテッド 遅延性総放出胃腸薬物送達システム
WO1999020316A1 (en) * 1997-10-20 1999-04-29 Board Of Regents, The University Of Texas System Single photon-emitting radiotraces and methods for their use
AU3870099A (en) * 1998-04-28 1999-11-16 Jagotec Ag Hyaluronan-based imaging agents
ATE393171T1 (de) * 1998-11-10 2008-05-15 Netech Inc Funktionelle chitosanderivate
US7067111B1 (en) * 1999-10-25 2006-06-27 Board Of Regents, University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
US6692724B1 (en) * 1999-10-25 2004-02-17 Board Of Regents, The University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
US6399951B1 (en) * 2000-02-02 2002-06-04 Ut-Battelle, Llc Simultaneous CT and SPECT tomography using CZT detectors
CA2406852A1 (en) * 2000-04-20 2001-11-01 The University Of British Columbia Radiometal complexes of 2-pyrrolylthiones and their use as radiopharmaceuticals for imaging and therapy
HUP0400758A3 (en) * 2000-11-03 2005-02-28 Bristol Myers Squibb Pharma Co Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation
US6623721B2 (en) * 2000-12-18 2003-09-23 Draximage, Inc. Bifunctional chelating compounds containing hydroxamic acid residues
US20030003048A1 (en) * 2001-04-26 2003-01-02 Chun Li Diagnostic imaging compositions, their methods of synthesis and use
GB0111204D0 (en) 2001-05-08 2001-06-27 Mertek Ltd High flux,high energy photon source
US7112340B2 (en) * 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
US7138105B2 (en) * 2002-02-27 2006-11-21 Pharmain Compositions for delivery of therapeutics and other materials, and methods of making and using the same
WO2003082301A1 (en) * 2002-03-29 2003-10-09 Threshold Pharmaceuticals, Inc. Compositions and methods for treating cancer
JP2005531647A (ja) * 2002-04-11 2005-10-20 カルボマー インク 新規なイメージングプローブ
US20040022729A1 (en) * 2002-07-31 2004-02-05 Uzgiris Egidijus E. Method for binding molecular agents to angiogencic blood vessels
US20040042959A1 (en) * 2002-08-28 2004-03-04 Michael Montalto Imaging cell death in vivo using non-radionuclide contrast agents
US7303741B2 (en) 2002-09-23 2007-12-04 General Electric Company Systems and methods for high-resolution in vivo imaging of biochemical activity in a living organism
KR101086690B1 (ko) * 2002-11-07 2011-11-25 셀>포인트, 엘엘씨 에틸렌디시스테인(ec)-약물 콘쥬게이트, 조성물 및조직 특이적 질환 영상 방법
US20050024380A1 (en) * 2003-07-28 2005-02-03 Lin Lin Method for reducing random access memory of IC in display devices
US7790141B2 (en) * 2003-08-11 2010-09-07 Pathak Holdings, Llc Radio-opaque compounds, compositions containing same and methods of their synthesis and use
US9050378B2 (en) * 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
EP1743174B1 (en) * 2004-04-20 2013-03-20 Emory University Multimodality nanostructures, methods of fabrication thereof, and methods of use thereof

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CA2593256A1 (en) 2006-07-13
KR20070106711A (ko) 2007-11-05
KR101313712B1 (ko) 2013-10-01
US20060182687A1 (en) 2006-08-17
US20120276005A1 (en) 2012-11-01
JP2008531755A (ja) 2008-08-14
IL184415A0 (en) 2008-12-29
BRPI0606395A2 (pt) 2009-06-23
AU2011200132B2 (en) 2012-10-11
AU2006204045B2 (en) 2010-10-14
WO2006074272A8 (en) 2006-12-28
AU2011200132A1 (en) 2011-02-03
US8147805B2 (en) 2012-04-03
EP1846042A2 (en) 2007-10-24
CN101137398B (zh) 2012-07-04
WO2006074272A3 (en) 2007-05-31
CN101137398A (zh) 2008-03-05
AU2006204045A1 (en) 2006-07-13
WO2006074272A2 (en) 2006-07-13

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