NO20074737L - Isokinolinforbindelser og fremgangsmater for anvendelse derav - Google Patents
Isokinolinforbindelser og fremgangsmater for anvendelse deravInfo
- Publication number
- NO20074737L NO20074737L NO20074737A NO20074737A NO20074737L NO 20074737 L NO20074737 L NO 20074737L NO 20074737 A NO20074737 A NO 20074737A NO 20074737 A NO20074737 A NO 20074737A NO 20074737 L NO20074737 L NO 20074737L
- Authority
- NO
- Norway
- Prior art keywords
- disease
- methods
- isoquinoline
- effective amount
- isoquinoline compounds
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 title 1
- AWJUIBRHMBBTKR-UHFFFAOYSA-N iso-quinoline Natural products C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 abstract 2
- -1 isoquinoline compound Chemical class 0.000 abstract 2
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- 206010012655 Diabetic complications Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 206010063837 Reperfusion injury Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 208000023589 ischemic disease Diseases 0.000 abstract 1
- 150000002537 isoquinolines Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
- 201000011531 vascular cancer Diseases 0.000 abstract 1
- 208000019553 vascular disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65663805P | 2005-02-25 | 2005-02-25 | |
| PCT/US2006/005290 WO2006093666A2 (en) | 2005-02-25 | 2006-02-15 | Isoqunoline compounds and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20074737L true NO20074737L (no) | 2007-11-14 |
Family
ID=36941607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074737A NO20074737L (no) | 2005-02-25 | 2007-09-17 | Isokinolinforbindelser og fremgangsmater for anvendelse derav |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20060287313A1 (pt) |
| EP (1) | EP1868607A4 (pt) |
| JP (1) | JP2008531561A (pt) |
| KR (1) | KR20070116016A (pt) |
| CN (1) | CN101252930A (pt) |
| AU (1) | AU2006219022A1 (pt) |
| BR (1) | BRPI0607703A2 (pt) |
| CA (1) | CA2597576A1 (pt) |
| IL (1) | IL185309A0 (pt) |
| MX (1) | MX2007010335A (pt) |
| NO (1) | NO20074737L (pt) |
| RU (1) | RU2007135355A (pt) |
| WO (1) | WO2006093666A2 (pt) |
| ZA (1) | ZA200707083B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030096833A1 (en) * | 2001-08-31 | 2003-05-22 | Jagtap Prakash G. | Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof |
| WO2005009398A2 (en) * | 2003-02-28 | 2005-02-03 | Inotek Pharmaceuticals Corporation | Tetracyclic benzamide derivatives and methods of use thereof |
| EA200601558A1 (ru) * | 2004-02-26 | 2007-08-31 | Инотек Фармасьютикалз Корпорейшн | Производные изохинолинов и способы их использования |
| CA2556738A1 (en) * | 2004-02-26 | 2005-09-09 | Inotek Pharmaceuticals Corporation | Tetracyclic lactam derivatives and uses thereof |
| CA2571001A1 (en) * | 2004-06-16 | 2006-01-26 | Inotek Pharmaceuticals Corporation | Methods for treating or preventing erectile dysfunction or urinary incontinence |
| JP2008531563A (ja) * | 2005-02-25 | 2008-08-14 | イノテック ファーマシューティカルズ コーポレイション | 四環スルホンアミド化合物およびこれらの使用法 |
| CA2598647A1 (en) * | 2005-02-25 | 2006-09-08 | Inotek Pharmaceuticals Corporation | Tetracyclic amino and carboxamido compounds and methods of use thereof |
| BRPI0615096A2 (pt) | 2005-08-24 | 2009-07-14 | Inotek Pharmaceuticals Corp | análogos de indenoisoquinolinona e métodos de uso dos mesmos |
| CN101674832A (zh) * | 2007-02-28 | 2010-03-17 | 伊诺泰克制药公司 | 茚并异喹啉酮类似物及其使用方法 |
| JP7791642B2 (ja) | 2017-05-24 | 2025-12-24 | ノバルティス アーゲー | 抗体－サイトカイングラフト化タンパク質及び癌の治療における使用方法 |
| US10016137B1 (en) | 2017-11-22 | 2018-07-10 | Hi Llc | System and method for simultaneously detecting phase modulated optical signals |
| US10420469B2 (en) | 2017-11-22 | 2019-09-24 | Hi Llc | Optical detection system for determining neural activity in brain based on water concentration |
| US10219700B1 (en) | 2017-12-15 | 2019-03-05 | Hi Llc | Systems and methods for quasi-ballistic photon optical coherence tomography in diffusive scattering media using a lock-in camera detector |
| US10368752B1 (en) | 2018-03-08 | 2019-08-06 | Hi Llc | Devices and methods to convert conventional imagers into lock-in cameras |
| US11857316B2 (en) | 2018-05-07 | 2024-01-02 | Hi Llc | Non-invasive optical detection system and method |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3710795A (en) * | 1970-09-29 | 1973-01-16 | Alza Corp | Drug-delivery device with stretched, rate-controlling membrane |
| IT1054655B (it) * | 1975-08-27 | 1981-11-30 | Lepetit Spa | Derivati condensati del l isochinolina |
| US4263304A (en) * | 1978-06-05 | 1981-04-21 | Sumitomo Chemical Company, Limited | 7 H-indolo[2,3-c]isoquinolines |
| US5177075A (en) * | 1988-08-19 | 1993-01-05 | Warner-Lambert Company | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process |
| GB8828806D0 (en) * | 1988-12-09 | 1989-01-18 | Beecham Group Plc | Novel compounds |
| US5260316A (en) * | 1991-07-30 | 1993-11-09 | Ciba-Geigy Corporation | Isoquinolyl substituted hydroxylamine derivatives |
| US5597831A (en) * | 1991-08-29 | 1997-01-28 | Vufb A.S | 6-[X-(2-hydroxyethyl) aminoalkyl]-5,11-dioxo-5,6-dihydro-11-H-indeno[1,2-c]isoquinolines and their use as antineoplastic agents |
| US5262564A (en) * | 1992-10-30 | 1993-11-16 | Octamer, Inc. | Sulfinic acid adducts of organo nitroso compounds useful as retroviral inactivating agents anti-retroviral agents and anti-tumor agents |
| TW440562B (en) * | 1994-05-20 | 2001-06-16 | Taiho Pharmaceutical Co Ltd | Condensed-indan derivative and pharmaceutically acceptable salts thereof |
| US6635642B1 (en) * | 1997-09-03 | 2003-10-21 | Guilford Pharmaceuticals Inc. | PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same |
| US6346536B1 (en) * | 1997-09-03 | 2002-02-12 | Guilford Pharmaceuticals Inc. | Poly(ADP-ribose) polymerase inhibitors and method for treating neural or cardiovascular tissue damage using the same |
| CA2341742A1 (en) * | 1998-08-24 | 2000-03-02 | Maxim Pharmaceuticals, Inc. | Activation and protection of t-cells (cd4+ and cd8+) using an h2 receptor agonist and other t-cell activating agents |
| US6346535B1 (en) * | 1999-01-29 | 2002-02-12 | American Cyanamid Company | Fungicidal mixtures |
| AU779215B2 (en) * | 1999-07-16 | 2005-01-13 | Maxim Pharmaceuticals, Inc. | Activation and protection of cytotoxic lymphocytes using a reactive oxygen metabolite inhibitor |
| US6277990B1 (en) * | 1999-12-07 | 2001-08-21 | Inotek Corporation | Substituted phenanthridinones and methods of use thereof |
| US6723733B2 (en) * | 2000-05-19 | 2004-04-20 | Guilford Pharmaceuticals, Inc. | Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses |
| AUPR201600A0 (en) * | 2000-12-11 | 2001-01-11 | Fujisawa Pharmaceutical Co., Ltd. | Quinazolinone derivative |
| US20030096833A1 (en) * | 2001-08-31 | 2003-05-22 | Jagtap Prakash G. | Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof |
| US6956035B2 (en) * | 2001-08-31 | 2005-10-18 | Inotek Pharmaceuticals Corporation | Isoquinoline derivatives and methods of use thereof |
| WO2005009398A2 (en) * | 2003-02-28 | 2005-02-03 | Inotek Pharmaceuticals Corporation | Tetracyclic benzamide derivatives and methods of use thereof |
| CA2556738A1 (en) * | 2004-02-26 | 2005-09-09 | Inotek Pharmaceuticals Corporation | Tetracyclic lactam derivatives and uses thereof |
| EA200601558A1 (ru) * | 2004-02-26 | 2007-08-31 | Инотек Фармасьютикалз Корпорейшн | Производные изохинолинов и способы их использования |
| CA2571001A1 (en) * | 2004-06-16 | 2006-01-26 | Inotek Pharmaceuticals Corporation | Methods for treating or preventing erectile dysfunction or urinary incontinence |
| WO2006039545A2 (en) * | 2004-09-30 | 2006-04-13 | Maxim Pharmaceuticals, Inc. | Use of parp-1 inhibitors for protecting tumorcidal lymphocytes from apoptosis |
| JP2008531563A (ja) * | 2005-02-25 | 2008-08-14 | イノテック ファーマシューティカルズ コーポレイション | 四環スルホンアミド化合物およびこれらの使用法 |
| CA2598647A1 (en) * | 2005-02-25 | 2006-09-08 | Inotek Pharmaceuticals Corporation | Tetracyclic amino and carboxamido compounds and methods of use thereof |
| BRPI0615096A2 (pt) * | 2005-08-24 | 2009-07-14 | Inotek Pharmaceuticals Corp | análogos de indenoisoquinolinona e métodos de uso dos mesmos |
-
2006
- 2006-02-15 KR KR1020077021984A patent/KR20070116016A/ko not_active Withdrawn
- 2006-02-15 JP JP2007557053A patent/JP2008531561A/ja active Pending
- 2006-02-15 AU AU2006219022A patent/AU2006219022A1/en not_active Abandoned
- 2006-02-15 MX MX2007010335A patent/MX2007010335A/es not_active Application Discontinuation
- 2006-02-15 CN CNA2006800059102A patent/CN101252930A/zh active Pending
- 2006-02-15 RU RU2007135355/04A patent/RU2007135355A/ru unknown
- 2006-02-15 WO PCT/US2006/005290 patent/WO2006093666A2/en not_active Ceased
- 2006-02-15 BR BRPI0607703-0A patent/BRPI0607703A2/pt not_active Application Discontinuation
- 2006-02-15 EP EP06748208A patent/EP1868607A4/en not_active Withdrawn
- 2006-02-15 US US11/355,285 patent/US20060287313A1/en not_active Abandoned
- 2006-02-15 CA CA002597576A patent/CA2597576A1/en not_active Abandoned
-
2007
- 2007-08-16 IL IL185309A patent/IL185309A0/en unknown
- 2007-08-22 ZA ZA200707083A patent/ZA200707083B/xx unknown
- 2007-09-17 NO NO20074737A patent/NO20074737L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2007135355A (ru) | 2009-03-27 |
| ZA200707083B (en) | 2008-12-31 |
| EP1868607A4 (en) | 2008-05-14 |
| KR20070116016A (ko) | 2007-12-06 |
| WO2006093666A3 (en) | 2006-10-26 |
| MX2007010335A (es) | 2007-11-06 |
| US20060287313A1 (en) | 2006-12-21 |
| CA2597576A1 (en) | 2006-09-08 |
| JP2008531561A (ja) | 2008-08-14 |
| AU2006219022A1 (en) | 2006-09-08 |
| BRPI0607703A2 (pt) | 2009-09-22 |
| EP1868607A2 (en) | 2007-12-26 |
| WO2006093666A2 (en) | 2006-09-08 |
| IL185309A0 (en) | 2008-02-09 |
| CN101252930A (zh) | 2008-08-27 |
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