NO20074742L - Farmakokinetisk forbedrede forbindelser - Google Patents

Farmakokinetisk forbedrede forbindelser

Info

Publication number
NO20074742L
NO20074742L NO20074742A NO20074742A NO20074742L NO 20074742 L NO20074742 L NO 20074742L NO 20074742 A NO20074742 A NO 20074742A NO 20074742 A NO20074742 A NO 20074742A NO 20074742 L NO20074742 L NO 20074742L
Authority
NO
Norway
Prior art keywords
improved compounds
pharmacokinetically improved
pharmacokinetically
improved
compounds
Prior art date
Application number
NO20074742A
Other languages
English (en)
Inventor
David Duffy
Michael Grogan
Steven Kates
Emanuele Ostuni
Olivier Schueller
Paul Sweetnam
Stewart Campbell
Original Assignee
Surface Logix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surface Logix Inc filed Critical Surface Logix Inc
Publication of NO20074742L publication Critical patent/NO20074742L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

En forbindelse med formel A med forbedrede egenskaper når det gjelder uspesifikk binding og forbedrede farmakokinetiske egenskaper eller et farmasøytisk aksepterbart salt, en stereoisomer eller et hydrat derav tilveiebringes, hvori A, B, D, E og substituentene R1-R3 er som beskrevet i søknaden .
NO20074742A 2005-02-18 2007-09-17 Farmakokinetisk forbedrede forbindelser NO20074742L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65393305P 2005-02-18 2005-02-18
PCT/US2006/006048 WO2006089276A2 (en) 2005-02-18 2006-02-21 Pharmacokinetically improved compounds

Publications (1)

Publication Number Publication Date
NO20074742L true NO20074742L (no) 2007-11-16

Family

ID=36917159

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074742A NO20074742L (no) 2005-02-18 2007-09-17 Farmakokinetisk forbedrede forbindelser

Country Status (19)

Country Link
US (2) US20080176844A1 (no)
EP (1) EP1850853A4 (no)
JP (1) JP2008530247A (no)
KR (1) KR20080016531A (no)
CN (2) CN102351862A (no)
AU (1) AU2006213985C1 (no)
BR (1) BRPI0608381A2 (no)
CA (1) CA2598271A1 (no)
CR (1) CR9381A (no)
EA (1) EA018668B1 (no)
GE (1) GEP20115184B (no)
IL (1) IL185344A0 (no)
MX (1) MX2007010144A (no)
NI (1) NI200700210A (no)
NO (1) NO20074742L (no)
NZ (1) NZ560963A (no)
UA (1) UA90502C2 (no)
WO (1) WO2006089276A2 (no)
ZA (1) ZA200707505B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA200701752A1 (ru) * 2005-02-18 2008-04-28 Сурфейс Логикс Инк. Способ получения усовершенствованных фармакокинетических соединений, включающих функциональные остатки или группы, и фармацевтические композиции, содержащие эти соединения
CR9465A (es) * 2005-03-25 2008-06-19 Surface Logix Inc Compuestos mejorados farmacocineticamente
US20120070443A1 (en) * 2008-12-02 2012-03-22 University Of Utah Research Foundation Pde1 as a target therapeutic in heart disease

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH445129A (fr) * 1964-04-29 1967-10-15 Nestle Sa Procédé pour la préparation de composés d'inclusion à poids moléculaire élevé
US3459731A (en) * 1966-12-16 1969-08-05 Corn Products Co Cyclodextrin polyethers and their production
US3453257A (en) * 1967-02-13 1969-07-01 Corn Products Co Cyclodextrin with cationic properties
US3426011A (en) * 1967-02-13 1969-02-04 Corn Products Co Cyclodextrins with anionic properties
US3453259A (en) * 1967-03-22 1969-07-01 Corn Products Co Cyclodextrin polyol ethers and their oxidation products
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4737323A (en) * 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5359115A (en) * 1992-03-26 1994-10-25 Affymax Technologies, N.V. Methods for the synthesis of phosphonate esters
US5288514A (en) * 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US5480971A (en) * 1993-06-17 1996-01-02 Houghten Pharmaceuticals, Inc. Peralkylated oligopeptide mixtures
US5440016A (en) * 1993-06-18 1995-08-08 Torrey Pines Institute For Molecular Studies Peptides of the formula (KFmoc) ZZZ and their uses
US5362899A (en) * 1993-09-09 1994-11-08 Affymax Technologies, N.V. Chiral synthesis of alpha-aminophosponic acids
CA2395558C (en) * 1997-11-12 2007-07-17 Bayer Aktiengesellschaft Intermediates for 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
US5958886A (en) * 1998-01-13 1999-09-28 Sigma-Tau Pharmaceuticals, Inc. Carnitine-containing peptides and a method for using the same
DE19827640A1 (de) * 1998-06-20 1999-12-23 Bayer Ag 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
KR100353014B1 (ko) * 1998-11-11 2002-09-18 동아제약 주식회사 발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물
GB9924020D0 (en) * 1999-10-11 1999-12-15 Pfizer Ltd Pharmaceutically active compounds
US6503908B1 (en) * 1999-10-11 2003-01-07 Pfizer Inc Pharmaceutically active compounds
MXPA02006240A (es) * 1999-12-24 2003-01-28 Bayer Ag Nuevas imidazo[1,3,5,) triazinonas y su uso.
WO2001047929A1 (de) * 1999-12-24 2001-07-05 Bayer Aktiengesellschaft Triazolotriazinone und ihre verwendung
US6548508B2 (en) * 2000-10-20 2003-04-15 Pfizer, Inc. Use of PDE V inhibitors for improved fecundity in mammals
DE10107639A1 (de) * 2001-02-15 2002-08-22 Bayer Ag 2-Alkoxyphenyl-substituierte Imidazotriazinone
GB0106661D0 (en) * 2001-03-16 2001-05-09 Pfizer Ltd Pharmaceutically active compounds
US6794387B2 (en) * 2001-03-28 2004-09-21 Pfizer Inc. Pharmaceutically active compounds

Also Published As

Publication number Publication date
US20080176844A1 (en) 2008-07-24
UA90502C2 (ru) 2010-05-11
BRPI0608381A2 (pt) 2009-12-29
IL185344A0 (en) 2008-02-09
CR9381A (es) 2008-06-19
EP1850853A2 (en) 2007-11-07
WO2006089276A2 (en) 2006-08-24
EA200701753A1 (ru) 2008-04-28
WO2006089276A3 (en) 2006-12-21
CA2598271A1 (en) 2006-08-24
AU2006213985A1 (en) 2006-08-24
KR20080016531A (ko) 2008-02-21
NZ560963A (en) 2010-11-26
US20100093719A1 (en) 2010-04-15
EA018668B1 (ru) 2013-09-30
GEP20115184B (en) 2011-03-25
AU2006213985C1 (en) 2012-03-15
CN102351862A (zh) 2012-02-15
CN101223171B (zh) 2011-09-14
CN101223171A (zh) 2008-07-16
AU2006213985B2 (en) 2011-08-25
MX2007010144A (es) 2008-02-15
NI200700210A (es) 2008-07-24
JP2008530247A (ja) 2008-08-07
ZA200707505B (en) 2009-08-26
EP1850853A4 (en) 2011-09-07

Similar Documents

Publication Publication Date Title
NZ592533A (en) METHOD FOR THE PREPARATION OF N-(5-CHLORO-2-PYRIDINYL)-2-[[4-[(DIMETHYLAMINO) IMINOMETHYL] BENZOYL] AMINO]-5-METHOXY-BENZAMIDE, A FACTOR Xa INHIBITOR
EA200800321A1 (ru) Ингибиторы гистондеацетилазы
MX2009011579A (es) Pirimidinonas como moduladores de caseina cinasa ii (ck2).
EA200801428A1 (ru) Производные пиридиазинона для лечения опухолей
NO20064077L (no) Kemokinreseptorantagonister
NO20044995L (no) Heterosykliske forbindelser
EA201000395A1 (ru) Фунгицидные производные 2-алкилтио-2-хинолинилоксиацетамида
EA200500203A1 (ru) Новый способ синтеза и новая кристаллическая форма агомелатина и фармацевтические композиции, которые её содержат
WO2005074603A3 (en) Aminobenzoxazoles as therapeutic agents
CY1109911T1 (el) Πυρρολοβενζοδιαζεπινες
WO2005110410A3 (en) Kinase inhibitors as therapeutic agents
MX2009009774A (es) Derivados de quinolina como fungicidas.
EA200801381A1 (ru) Производные пиримидина
WO2007048064A3 (en) Amino-pyrimidines as casein kinase ii (ck2) modulators
EA201000396A1 (ru) Новые фунгициды
EA201001124A1 (ru) Производные хинолина и их применение в качестве фунгицидов
WO2006072393A3 (de) Sulfonylpyrrolidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE60334536D1 (de) Furylverbindungen
EA200702670A1 (ru) Препарат тиенопиридинового ингибитора агрегации тромбоцитов
DE60333746D1 (de) Thienylverbindungen
EA200700096A1 (ru) Производные 2-карбамид-4-фенилтиазола, способ их получения и их применение в терапии
TW200637837A (en) Fungicides
BRPI0714885B8 (pt) compostos terapêuticos e seu uso
WO2007002313A3 (en) Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants
EA200801608A1 (ru) Производные бензимидазолонкарбоновой кислоты

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application