NO20074897L - Radioaktive halogenmerkede fenyloksyanilinderivater - Google Patents
Radioaktive halogenmerkede fenyloksyanilinderivaterInfo
- Publication number
- NO20074897L NO20074897L NO20074897A NO20074897A NO20074897L NO 20074897 L NO20074897 L NO 20074897L NO 20074897 A NO20074897 A NO 20074897A NO 20074897 A NO20074897 A NO 20074897A NO 20074897 L NO20074897 L NO 20074897L
- Authority
- NO
- Norway
- Prior art keywords
- radioactive halogen
- pbr
- labeled
- alkoxy group
- compound useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/88—Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Et radioaktivt halogenmerket fenyloksyanilinderivat representert ved den følgende formel: hvor R1 representerer en gruppe slik som en alkylgruppe; Xl, X2, X3 og X4 representerer hver et hydrogenatom, en alkylgruppe, en alkoksygruppe, en alkoksygruppe som bærer 11C introdusert deri eller et radioaktivt halogenatom, tilveiebrakt at minst en av Xl, X2, X3 og X4 representerer en alkoksygruppe som bærer 11C introdusert deri eller et radioaktivt halogenatom; som er en forbindelse nyttig som en PBR-ligand som har en høy affinitet og en høy selektivitet I in vitro måling av PBR er en PBR-ligand som har en høy affinitet og en høy selektivitet merket med en radioaktiv halogen nukleær art for a muliggjøre målingen av PBR in vivo med anvendelsen av midler ikke bare inkluderende PET, men også SPECT. En forbindelse som er nyttig i tidlig diagnostikk, forebygging og behandling av sykdommer slik som Alzheimers type demens kan på denne måten bli oppnådd.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005052527 | 2005-02-28 | ||
| PCT/JP2005/024075 WO2006092902A1 (ja) | 2005-02-28 | 2005-12-28 | 放射性ハロゲン標識フェニルオキシアニリン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20074897L true NO20074897L (no) | 2007-11-21 |
Family
ID=36940944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074897A NO20074897L (no) | 2005-02-28 | 2007-09-26 | Radioaktive halogenmerkede fenyloksyanilinderivater |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20090234162A1 (no) |
| EP (1) | EP1854781A1 (no) |
| JP (1) | JPWO2006092902A1 (no) |
| KR (1) | KR20070108883A (no) |
| CN (1) | CN101133017A (no) |
| AU (1) | AU2005328464B2 (no) |
| BR (1) | BRPI0520092A2 (no) |
| CA (1) | CA2599321A1 (no) |
| IL (1) | IL185333A0 (no) |
| MX (1) | MX2007010343A (no) |
| NO (1) | NO20074897L (no) |
| RU (1) | RU2425824C2 (no) |
| UA (1) | UA93870C2 (no) |
| WO (1) | WO2006092902A1 (no) |
| ZA (1) | ZA200707226B (no) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101563305A (zh) * | 2006-12-21 | 2009-10-21 | 哈默史密斯网上成像有限公司 | 放射性标记方法 |
| CA2680762A1 (en) * | 2007-03-12 | 2008-09-25 | National Institute Of Radiological Sciences | Pet visualization of amyloid-associated neuroinflammation in the brain |
| EP1997515A1 (en) * | 2007-05-30 | 2008-12-03 | Bayer Schering Pharma Aktiengesellschaft | Use of radiolabelled phenyloxyaniline derivatives for imaging diseases associated with peripheral benzodiazepin receptor's activation |
| JP5441060B2 (ja) * | 2007-10-31 | 2014-03-12 | 独立行政法人理化学研究所 | 創薬のためのｐｅｔスクリーニング用分子プローブを製造するためのキット |
| GB0722779D0 (en) | 2007-11-20 | 2008-01-02 | Sterix Ltd | Compound |
| GB0904715D0 (en) | 2009-03-19 | 2009-05-06 | Ge Healthcare Ltd | Aryloxyanilide derivataives |
| GB0921967D0 (en) | 2009-12-17 | 2010-02-03 | Ge Healthcare Ltd | Novel Aryloxyanilide Derivatives |
| JP5422782B1 (ja) * | 2012-12-21 | 2014-02-19 | 独立行政法人放射線医学総合研究所 | 脳内に蓄積したタウタンパク質をイメージングするための新規化合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5122361A (en) * | 1989-04-17 | 1992-06-16 | Trustees Of The University Of Pennsylvania | Dopamine receptor ligands and imaging agents |
| US5993777A (en) * | 1993-05-06 | 1999-11-30 | Research Corporation Technologies, Inc. | Benzamide compounds for cancer imaging and therapy |
| JP4302207B2 (ja) * | 1997-08-04 | 2009-07-22 | 大正製薬株式会社 | アリールオキシアニリン誘導体 |
| DE69809063T2 (de) * | 1997-08-04 | 2003-06-12 | Nihon Nohyaku Co., Ltd. | Aryloxyanilin-derivate |
| AU4975600A (en) * | 1999-04-26 | 2000-11-10 | Emory University | 4-fluoroalkyl-3-halophenyl nortropanes |
| US6843979B2 (en) * | 1999-04-26 | 2005-01-18 | Emory University | 4-haloethenylphenyl tropane:serotonin transporter imaging agents |
| RU2300516C2 (ru) * | 1999-11-05 | 2007-06-10 | Эмисфере Текнолоджиз, Инк. | Соединения феноксикарбоновой кислоты и композиции для доставки активных веществ |
| US6870069B2 (en) * | 2003-01-10 | 2005-03-22 | National Institute Of Radiological Sciences | Phenyloxyaniline derivatives |
-
2005
- 2005-12-28 RU RU2007135882/04A patent/RU2425824C2/ru not_active IP Right Cessation
- 2005-12-28 AU AU2005328464A patent/AU2005328464B2/en not_active Ceased
- 2005-12-28 CA CA002599321A patent/CA2599321A1/en not_active Abandoned
- 2005-12-28 WO PCT/JP2005/024075 patent/WO2006092902A1/ja not_active Ceased
- 2005-12-28 BR BRPI0520092-0A patent/BRPI0520092A2/pt not_active IP Right Cessation
- 2005-12-28 MX MX2007010343A patent/MX2007010343A/es not_active Application Discontinuation
- 2005-12-28 US US11/884,763 patent/US20090234162A1/en not_active Abandoned
- 2005-12-28 UA UAA200710682A patent/UA93870C2/ru unknown
- 2005-12-28 ZA ZA200707226A patent/ZA200707226B/xx unknown
- 2005-12-28 CN CNA2005800488048A patent/CN101133017A/zh active Pending
- 2005-12-28 EP EP05822458A patent/EP1854781A1/en not_active Withdrawn
- 2005-12-28 KR KR1020077019539A patent/KR20070108883A/ko not_active Ceased
- 2005-12-28 JP JP2007505812A patent/JPWO2006092902A1/ja active Pending
-
2007
- 2007-08-16 IL IL185333A patent/IL185333A0/en unknown
- 2007-09-26 NO NO20074897A patent/NO20074897L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1854781A1 (en) | 2007-11-14 |
| CA2599321A1 (en) | 2006-09-08 |
| UA93870C2 (ru) | 2011-03-25 |
| RU2007135882A (ru) | 2009-04-10 |
| BRPI0520092A2 (pt) | 2009-08-18 |
| AU2005328464B2 (en) | 2011-02-24 |
| AU2005328464A1 (en) | 2006-09-08 |
| KR20070108883A (ko) | 2007-11-13 |
| ZA200707226B (en) | 2009-09-30 |
| JPWO2006092902A1 (ja) | 2008-08-07 |
| WO2006092902A1 (ja) | 2006-09-08 |
| CN101133017A (zh) | 2008-02-27 |
| MX2007010343A (es) | 2008-04-16 |
| RU2425824C2 (ru) | 2011-08-10 |
| US20090234162A1 (en) | 2009-09-17 |
| IL185333A0 (en) | 2008-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |