NO20076307L - Fremgangsmater for a fremstille biarylurinstoffer og analoger derav - Google Patents

Fremgangsmater for a fremstille biarylurinstoffer og analoger derav

Info

Publication number
NO20076307L
NO20076307L NO20076307A NO20076307A NO20076307L NO 20076307 L NO20076307 L NO 20076307L NO 20076307 A NO20076307 A NO 20076307A NO 20076307 A NO20076307 A NO 20076307A NO 20076307 L NO20076307 L NO 20076307L
Authority
NO
Norway
Prior art keywords
preparing
analogs
biarylurine
substances
methods
Prior art date
Application number
NO20076307A
Other languages
English (en)
Inventor
John R Snoonian
Adam Looker
Graham Ansell
Todd A Blythe
Andrew D Jones
Benjamin Littler
Philip L Nyce
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20076307L publication Critical patent/NO20076307L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Foreliggende oppfinnelse vedrører fremgangsmåter for å fremstille biarylureaderivater og analoger derav. Oppfinnelsen tilveiebringer også forbindelser som er nyttige som mellomprodukter i fremgangsmåtene ifølge foreliggende oppfinnelse. Fremgangsmåten er nyttig for å fremstille forbindelser som hemmer IMPDH.
NO20076307A 2005-05-09 2007-12-07 Fremgangsmater for a fremstille biarylurinstoffer og analoger derav NO20076307L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67902205P 2005-05-09 2005-05-09
PCT/US2006/017817 WO2006122072A2 (en) 2005-05-09 2006-05-09 Processes for preparing biaryl ureas and analogs thereof

Publications (1)

Publication Number Publication Date
NO20076307L true NO20076307L (no) 2007-12-07

Family

ID=37101964

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076307A NO20076307L (no) 2005-05-09 2007-12-07 Fremgangsmater for a fremstille biarylurinstoffer og analoger derav

Country Status (15)

Country Link
US (2) US7544810B2 (no)
EP (1) EP1879858A2 (no)
JP (1) JP2008543742A (no)
KR (1) KR20080015433A (no)
CN (1) CN101175718A (no)
AU (1) AU2006244173A1 (no)
BR (1) BRPI0608602A2 (no)
CA (1) CA2606780A1 (no)
IL (1) IL186803A (no)
MX (1) MX2007014187A (no)
NO (1) NO20076307L (no)
NZ (1) NZ563478A (no)
RU (1) RU2431630C2 (no)
WO (1) WO2006122072A2 (no)
ZA (1) ZA200709241B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11760701B2 (en) 2018-02-27 2023-09-19 The Research Foundation For The State University Of New Yrok Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same
MX2022006865A (es) 2019-12-06 2022-07-11 Vertex Pharma Tetrahidrofuranos sustituidos como moduladores de canales de sodio.
CN117794920A (zh) 2021-06-04 2024-03-29 沃泰克斯药物股份有限公司 N-(羟烷基(杂)芳基)四氢呋喃甲酰胺作为钠通道调节剂

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA20A (en) * 1869-08-26 W. Milner Improvements in sleighs and cutters for supporting the sleigh or cutter box
CA26A (en) * 1869-09-07 A. Kennedy A land roller
CA15A (en) * 1869-08-20 J.P. Johnston A machine for coupling railway carriages
US6054472A (en) * 1996-04-23 2000-04-25 Vertex Pharmaceuticals, Incorporated Inhibitors of IMPDH enzyme
US5807876A (en) 1996-04-23 1998-09-15 Vertex Pharmaceuticals Incorporated Inhibitors of IMPDH enzyme
CZ298463B6 (cs) * 1996-04-23 2007-10-10 Vertex Pharmaceuticals Incorporated Deriváty mocoviny pro použití jako inhibitory IMPDH enzymu a farmaceutické prostredky, které je obsahují
US6420403B1 (en) * 1998-10-29 2002-07-16 Edwin J. Iwanowicz Inhibitors of IMPDH enzyme
SK13332001A3 (sk) 1999-03-19 2002-02-05 Vertex Pharmaceuticals Incorporated Inhibítory IMPDH enzýmu a ich použitie
WO2001099028A1 (en) * 2000-06-21 2001-12-27 Exxonmobil Upstream Research Company Orthogonal triaxial acoustic receiver

Also Published As

Publication number Publication date
RU2007145420A (ru) 2009-06-20
IL186803A (en) 2012-02-29
CA2606780A1 (en) 2006-11-16
IL186803A0 (en) 2008-02-09
EP1879858A2 (en) 2008-01-23
JP2008543742A (ja) 2008-12-04
US20090221835A1 (en) 2009-09-03
ZA200709241B (en) 2009-02-25
BRPI0608602A2 (pt) 2010-01-19
RU2431630C2 (ru) 2011-10-20
US7544810B2 (en) 2009-06-09
AU2006244173A1 (en) 2006-11-16
KR20080015433A (ko) 2008-02-19
CN101175718A (zh) 2008-05-07
US20080021222A1 (en) 2008-01-24
WO2006122072A3 (en) 2007-05-03
US7777048B2 (en) 2010-08-17
NZ563478A (en) 2011-04-29
MX2007014187A (es) 2008-01-24
WO2006122072A2 (en) 2006-11-16

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Legal Events

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