NO20081180L - Oxazolidinone-quinolone hybrids as antibacterial compounds - Google Patents
Oxazolidinone-quinolone hybrids as antibacterial compoundsInfo
- Publication number
- NO20081180L NO20081180L NO20081180A NO20081180A NO20081180L NO 20081180 L NO20081180 L NO 20081180L NO 20081180 A NO20081180 A NO 20081180A NO 20081180 A NO20081180 A NO 20081180A NO 20081180 L NO20081180 L NO 20081180L
- Authority
- NO
- Norway
- Prior art keywords
- oxazolidinone
- antibacterial compounds
- haloalkyl
- alkyl
- quinolone hybrids
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- HGKANZZLRDQFIM-UHFFFAOYSA-N 1,3-oxazolidin-2-one;1h-quinolin-2-one Chemical compound O=C1NCCO1.C1=CC=C2NC(=O)C=CC2=C1 HGKANZZLRDQFIM-UHFFFAOYSA-N 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000006583 (C1-C3) haloalkyl group Chemical group 0.000 abstract 1
- DRLPWCAENQZXJT-UHFFFAOYSA-N 2-[(dimethylazaniumyl)amino]acetate Chemical compound CN(C)NCC(O)=O DRLPWCAENQZXJT-UHFFFAOYSA-N 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 229910004727 OSO3H Inorganic materials 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2005008573 | 2005-08-08 | ||
| PCT/IB2006/052714 WO2007017828A2 (en) | 2005-08-08 | 2006-08-07 | Oxazolidinone-quinolone hybrids as antibacterial compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20081180L true NO20081180L (no) | 2008-04-15 |
Family
ID=37620798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20081180A NO20081180L (no) | 2005-08-08 | 2008-03-06 | Oxazolidinone-quinolone hybrids as antibacterial compounds |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20100222302A1 (pt) |
| EP (2) | EP2256120A1 (pt) |
| JP (1) | JP2009504631A (pt) |
| KR (1) | KR20080038397A (pt) |
| CN (1) | CN101238135B (pt) |
| AR (1) | AR054608A1 (pt) |
| AU (1) | AU2006277662A1 (pt) |
| BR (1) | BRPI0614730A2 (pt) |
| CA (1) | CA2616977A1 (pt) |
| IL (1) | IL189322A0 (pt) |
| MX (1) | MX2008001415A (pt) |
| NO (1) | NO20081180L (pt) |
| RU (1) | RU2008108477A (pt) |
| TW (1) | TW200740829A (pt) |
| WO (1) | WO2007017828A2 (pt) |
| ZA (1) | ZA200802194B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003031443A1 (en) | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety |
| KR101101982B1 (ko) | 2003-04-30 | 2012-01-02 | 모르포켐 악티엥게셀샤프트 퓌르 콤비나토리셰 케미 | 옥사졸리디논-퀴놀린 하이브리드 항생제의 탄저병 및 기타감염증의 치료용의 용도 |
| DE10340485B4 (de) | 2003-09-03 | 2015-05-13 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden |
| ATE401326T1 (de) | 2003-12-18 | 2008-08-15 | Morphochem Ag Komb Chemie | Oxazolidinon-chinolon hybrid antibiotika |
| US8158797B2 (en) | 2003-12-18 | 2012-04-17 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| CN101300248A (zh) * | 2005-04-21 | 2008-11-05 | 塔甘塔治疗公司 | 膦酸酯化的氟喹诺酮、其抗菌类似物以及预防和治疗骨和关节感染的方法 |
| US8124623B2 (en) | 2006-11-10 | 2012-02-28 | Actelion Pharmaceuticals Ltd. | 5-hydroxymethyl-oxazolidin-2-one-derivatives and their uses as antibacterials |
| CL2007003332A1 (es) | 2006-11-24 | 2008-06-20 | Actelion Pharmaceuticals Ltd | Compuestos derivados de heterociclos condensados; compuestos intermediarios; composicion farmaceutica; y uso en la prevencion o tratamiento de infecciones bacterianas. |
| CL2008001002A1 (es) | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| WO2011031744A1 (en) * | 2009-09-09 | 2011-03-17 | Achaogen, Inc. | Antibacterial fluoroquinolone analogs |
| MX363678B (es) | 2013-05-28 | 2019-03-29 | Morphochem Aktiengesellschaft Fuer Komb Torische Chemie | Terapia de combinación que comprende oxazolidinona-quinolonas para usarse en el tratamiento de infecciones bacterianas. |
| HUE043786T2 (hu) | 2013-05-28 | 2019-09-30 | Morphochem Gmbh | Oxazolidinon-kinolon hibrid antibakteriális hatóanyagok adagolása |
| US10087171B2 (en) | 2016-12-19 | 2018-10-02 | Actelion Pharmaceuticals Ltd | Crystalline forms of cadazolid |
| KR102476708B1 (ko) | 2017-11-01 | 2022-12-09 | 삼성전자주식회사 | 광학 필터, 및 이를 포함하는 카메라 모듈 및 전자 장치 |
| KR102673362B1 (ko) * | 2018-03-27 | 2024-06-05 | 삼성전자주식회사 | 근적외선 흡수 필름, 광학 필터 및 전자 장치 |
| CN115772176A (zh) * | 2022-12-02 | 2023-03-10 | 常州兰陵制药有限公司 | 左氧氟沙星关键药物中间体的合成方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE72668T1 (de) * | 1985-09-24 | 1992-03-15 | Hoffmann La Roche | Chinolinderivate. |
| AU618235B2 (en) | 1986-03-31 | 1991-12-19 | Sankyo Company Limited | Quinoline-3-carboxylic acid derivatives, their preparation and use |
| JPH04128288A (ja) * | 1990-09-18 | 1992-04-28 | Teikoku Chem Ind Corp Ltd | キノロンカルボン酸誘導体及びその製造方法 |
| ATE319710T1 (de) * | 2000-12-21 | 2006-03-15 | Pharmacia & Upjohn Co Llc | Antimikrobielle chinolonderivate und ihre verwendung zur behandlung bakterieller infektionen |
| WO2003031443A1 (en) | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety |
| DK1474420T3 (da) | 2002-02-01 | 2012-05-21 | Astrazeneca Ab | Quinazolinforbindelser |
| US6803469B2 (en) | 2002-08-05 | 2004-10-12 | The Procter & Gamble Company | Process for preparing quinolone antibiotic intermediates |
| KR101101982B1 (ko) | 2003-04-30 | 2012-01-02 | 모르포켐 악티엥게셀샤프트 퓌르 콤비나토리셰 케미 | 옥사졸리디논-퀴놀린 하이브리드 항생제의 탄저병 및 기타감염증의 치료용의 용도 |
| ATE471937T1 (de) * | 2003-07-02 | 2010-07-15 | Merck Sharp & Dohme | Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon |
| ATE401326T1 (de) * | 2003-12-18 | 2008-08-15 | Morphochem Ag Komb Chemie | Oxazolidinon-chinolon hybrid antibiotika |
-
2006
- 2006-08-03 AR ARP060103389A patent/AR054608A1/es unknown
- 2006-08-07 KR KR1020087005799A patent/KR20080038397A/ko not_active Ceased
- 2006-08-07 RU RU2008108477/04A patent/RU2008108477A/ru not_active Application Discontinuation
- 2006-08-07 AU AU2006277662A patent/AU2006277662A1/en not_active Abandoned
- 2006-08-07 CN CN2006800290493A patent/CN101238135B/zh not_active Expired - Fee Related
- 2006-08-07 TW TW095128893A patent/TW200740829A/zh unknown
- 2006-08-07 WO PCT/IB2006/052714 patent/WO2007017828A2/en not_active Ceased
- 2006-08-07 BR BRPI0614730A patent/BRPI0614730A2/pt not_active IP Right Cessation
- 2006-08-07 EP EP10004213A patent/EP2256120A1/en not_active Withdrawn
- 2006-08-07 US US12/063,305 patent/US20100222302A1/en not_active Abandoned
- 2006-08-07 MX MX2008001415A patent/MX2008001415A/es not_active Application Discontinuation
- 2006-08-07 JP JP2008525696A patent/JP2009504631A/ja active Pending
- 2006-08-07 EP EP06795600A patent/EP1931684A2/en not_active Withdrawn
- 2006-08-07 CA CA002616977A patent/CA2616977A1/en not_active Abandoned
-
2008
- 2008-02-06 IL IL189322A patent/IL189322A0/en unknown
- 2008-03-06 NO NO20081180A patent/NO20081180L/no not_active Application Discontinuation
- 2008-03-07 ZA ZA200802194A patent/ZA200802194B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL189322A0 (en) | 2008-06-05 |
| US20100222302A1 (en) | 2010-09-02 |
| WO2007017828A2 (en) | 2007-02-15 |
| BRPI0614730A2 (pt) | 2016-11-01 |
| MX2008001415A (es) | 2008-04-04 |
| RU2008108477A (ru) | 2009-09-20 |
| WO2007017828A3 (en) | 2007-07-19 |
| TW200740829A (en) | 2007-11-01 |
| CN101238135B (zh) | 2011-05-11 |
| EP2256120A1 (en) | 2010-12-01 |
| CN101238135A (zh) | 2008-08-06 |
| CA2616977A1 (en) | 2007-02-15 |
| ZA200802194B (en) | 2009-03-25 |
| EP1931684A2 (en) | 2008-06-18 |
| JP2009504631A (ja) | 2009-02-05 |
| AR054608A1 (es) | 2007-06-27 |
| KR20080038397A (ko) | 2008-05-06 |
| AU2006277662A1 (en) | 2007-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |