NO20082679L - Sammensetning og fremgangsmate for a behandle CNS lidelser - Google Patents
Sammensetning og fremgangsmate for a behandle CNS lidelserInfo
- Publication number
- NO20082679L NO20082679L NO20082679A NO20082679A NO20082679L NO 20082679 L NO20082679 L NO 20082679L NO 20082679 A NO20082679 A NO 20082679A NO 20082679 A NO20082679 A NO 20082679A NO 20082679 L NO20082679 L NO 20082679L
- Authority
- NO
- Norway
- Prior art keywords
- composition
- cns disorders
- treating cns
- treatment
- thienopyridinone
- Prior art date
Links
- 208000015114 central nervous system disease Diseases 0.000 title 1
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
- 108091005482 5-HT4 receptors Proteins 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000004962 physiological condition Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/271,019 US7598265B2 (en) | 2004-09-30 | 2005-11-10 | Compositions and methods for treating CNS disorders |
| PCT/US2006/043140 WO2007058805A2 (fr) | 2005-11-10 | 2006-11-06 | Compositions et procedes destines au traitement des troubles du snc |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20082679L true NO20082679L (no) | 2008-06-10 |
Family
ID=37946751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20082679A NO20082679L (no) | 2005-11-10 | 2008-06-10 | Sammensetning og fremgangsmate for a behandle CNS lidelser |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7598265B2 (fr) |
| EP (1) | EP1959954A2 (fr) |
| JP (1) | JP2009515877A (fr) |
| KR (1) | KR20080067001A (fr) |
| CN (1) | CN101340908A (fr) |
| AR (1) | AR057887A1 (fr) |
| AU (1) | AU2006315854A1 (fr) |
| BR (1) | BRPI0618493A2 (fr) |
| CA (1) | CA2629312C (fr) |
| CR (1) | CR10062A (fr) |
| EA (1) | EA200801302A1 (fr) |
| IL (1) | IL191168A0 (fr) |
| MA (1) | MA30037B1 (fr) |
| NO (1) | NO20082679L (fr) |
| TW (1) | TW200735868A (fr) |
| WO (1) | WO2007058805A2 (fr) |
| ZA (1) | ZA200804951B (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7612078B2 (en) * | 2003-03-31 | 2009-11-03 | Epix Delaware, Inc. | Piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US20050222175A1 (en) * | 2004-03-31 | 2005-10-06 | Dhanoa Dale S | New piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US7488736B2 (en) * | 2004-05-17 | 2009-02-10 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US7598265B2 (en) * | 2004-09-30 | 2009-10-06 | Epix Delaware, Inc. | Compositions and methods for treating CNS disorders |
| US7576211B2 (en) * | 2004-09-30 | 2009-08-18 | Epix Delaware, Inc. | Synthesis of thienopyridinone compounds and related intermediates |
| US7407966B2 (en) * | 2004-10-07 | 2008-08-05 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| EP1856075A1 (fr) * | 2005-01-25 | 2007-11-21 | Epix Delaware, Inc. | Composes d'arylamine substitues et leur utilisation comme modulateurs de 5-ht6 |
| GB0526258D0 (en) * | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
| EP2445877B1 (fr) * | 2008-12-03 | 2014-07-23 | Nanotherapeutics, Inc. | Composés bicycliques et leurs procédés de fabrication et d'utilisation |
| JP2012523437A (ja) * | 2009-04-13 | 2012-10-04 | セラヴァンス， インコーポレーテッド | 認知障害の治療のための５−ｈｔ４受容体アゴニスト化合物 |
| US20230139125A1 (en) * | 2021-02-04 | 2023-05-04 | Richard Natrillo | Dietary supplement for improving brain performance |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3069412A (en) | 1958-08-15 | 1962-12-18 | Fmc Corp | N-aminoazetidine and preparation thereof |
| CA933923A (en) | 1969-12-19 | 1973-09-18 | Eichenberger Kurt | Process for the manufacture of new thiopyranes |
| GB1570494A (en) | 1975-11-28 | 1980-07-02 | Ici Ltd | Thienopyrimidine derivatives and their use as pesticides |
| DE2925175A1 (de) | 1979-06-22 | 1981-01-08 | Basf Ag | Verfahren zur herstellung von isatosaeureanhydriden |
| IT1203323B (it) | 1987-02-02 | 1989-02-15 | Hoechst Italia Spa | Additivo fotoattivatore per composizioni polimeriche costituito dal sale metallico di una cera ossidata |
| US5236917A (en) | 1989-05-04 | 1993-08-17 | Sterling Winthrop Inc. | Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof |
| DE4008726A1 (de) | 1990-03-19 | 1991-09-26 | Basf Ag | Thieno(2,3-d)pyrimidinderivate |
| DE4023270A1 (de) * | 1990-07-21 | 1992-02-06 | Hoechst Ag | Hydrophile mischpolymere sowie deren verwendung in der reprographie |
| US5219864A (en) | 1991-03-12 | 1993-06-15 | Kyowa Hakko Kogyo Co., Ltd. | Thienopyridine derivatives |
| US5155115A (en) * | 1991-03-12 | 1992-10-13 | Kyowa Hakko Kogyo Co., Ltd. | Thienopyridine derivatives |
| US5227387A (en) | 1991-09-03 | 1993-07-13 | Dowelanco | Quinoline nematicidal method |
| DE4138820A1 (de) | 1991-11-26 | 1993-05-27 | Basf Ag | Chinolin-3-carbonsaeureamide, deren herstellung und verwendung |
| DE4208254A1 (de) | 1992-03-14 | 1993-09-16 | Hoechst Ag | Substituierte pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel und fungizid |
| DE4227747A1 (de) | 1992-08-21 | 1994-02-24 | Basf Ag | Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung |
| US5409948A (en) | 1992-11-23 | 1995-04-25 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for treating cognitive disorders with phenserine |
| JPH06239858A (ja) | 1993-02-16 | 1994-08-30 | Otsuka Pharmaceut Co Ltd | 末梢血管拡張剤 |
| GB9306460D0 (en) | 1993-03-29 | 1993-05-19 | Smithkline Beecham Plc | Novel compounds |
| JPH07324087A (ja) * | 1994-04-04 | 1995-12-12 | Taisho Pharmaceut Co Ltd | 複素環化合物 |
| TW449600B (en) | 1994-04-19 | 2001-08-11 | Takeda Chemical Industries Ltd | Condensed-ring thiophene derivatives, their production and use |
| JP3829879B2 (ja) | 1994-05-18 | 2006-10-04 | 大正製薬株式会社 | キノリンカルボン酸誘導体 |
| GB2295387A (en) | 1994-11-23 | 1996-05-29 | Glaxo Inc | Quinazoline antagonists of alpha 1c adrenergic receptors |
| DE19636769A1 (de) | 1996-09-10 | 1998-03-12 | Basf Ag | 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| US6979309B2 (en) * | 1997-02-14 | 2005-12-27 | Nxstage Medical Inc. | Systems and methods for performing blood processing and/or fluid exchange procedures |
| DE19724980A1 (de) | 1997-06-13 | 1998-12-17 | Basf Ag | 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| JPH11130777A (ja) | 1997-08-13 | 1999-05-18 | Takeda Chem Ind Ltd | チエノピリジン誘導体、その中間体およびそれらの製造法 |
| WO1999018077A1 (fr) | 1997-10-02 | 1999-04-15 | Eisai Co., Ltd. | Derives de pyridine condenses |
| WO1999043681A1 (fr) | 1998-02-26 | 1999-09-02 | Neurogen Corporation | Pyridines heteroaryle fondues substituees 4-(4-piperidylmethylamino); ligands du recepteur cerebral gaba |
| DE19815026A1 (de) | 1998-04-03 | 1999-10-07 | Hoechst Schering Agrevo Gmbh | Substituierte Piperidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und Fungizide |
| AU4541999A (en) * | 1998-04-08 | 1999-10-25 | Gary S. Moshier | System for launched munition neutralization of buried mines, subsystems and components thereof |
| NZ508314A (en) | 1998-06-02 | 2004-03-26 | Osi Pharm Inc | Pyrrolo[2,3d]pyrimidine compositions and their use |
| US6232320B1 (en) | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| JP2002542287A (ja) | 1999-04-28 | 2002-12-10 | レスピラトリウス アクチボラゲット | 医 薬 |
| SE9902987D0 (sv) | 1999-08-24 | 1999-08-24 | Astra Pharma Prod | Novel compounds |
| WO2001025218A1 (fr) | 1999-10-01 | 2001-04-12 | Japan Energy Corporation | Nouveaux derives de quinazoline |
| EP1270568A1 (fr) | 2001-06-19 | 2003-01-02 | Biofrontera Pharmaceuticals AG | 1-Méthyl-4-(3-éthoxy-9H-thioxanthène-ylidène)-pipéridine et son utilasition en tant qu'antagoniste du recepteur 5-HT2B et/ou H1 |
| WO2003020728A1 (fr) | 2001-08-30 | 2003-03-13 | Pharmacia & Upjohn Company | Agents antiviraux a base de 4-thioxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carbothioamides |
| MXPA03000145A (es) | 2002-01-07 | 2003-07-15 | Pfizer | Compuestos de oxo u oxi-piridina como moduladores de receptores 5-ht4. |
| WO2004034963A2 (fr) | 2002-05-17 | 2004-04-29 | Eisai Co., Ltd. | Methodes et compositions utilisant des inhibiteurs de la cholinesterase |
| US20040138238A1 (en) | 2002-08-08 | 2004-07-15 | Dhanoa Dale S. | Substituted aminopyrimidine compounds as neurokinin antagonists |
| WO2004017950A2 (fr) | 2002-08-22 | 2004-03-04 | Piramed Limited | Inhibiteurs de phosphatidylinositol 3,5-biphosphate en tant qu'agents antiviraux |
| WO2004030629A2 (fr) | 2002-10-01 | 2004-04-15 | Predix Pharmaceuticals | Nouveaux antagonistes de la neurokinine et leurs procedes d'utilisation |
| US7153858B2 (en) | 2003-01-31 | 2006-12-26 | Epix Delaware, Inc. | Arylpiperazinyl compounds |
| US20050222175A1 (en) | 2004-03-31 | 2005-10-06 | Dhanoa Dale S | New piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| WO2004089312A2 (fr) | 2003-03-31 | 2004-10-21 | Predix Pharmaceuticals Holdings, Inc. | Nouveaux composes de piperidinylamino-thieno[2,3-d] pyrimidine |
| US7612078B2 (en) | 2003-03-31 | 2009-11-03 | Epix Delaware, Inc. | Piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US7119205B2 (en) | 2003-05-16 | 2006-10-10 | Abbott Laboratories | Thienopyridones as AMPK activators for the treatment of diabetes and obesity |
| ATE374030T1 (de) | 2003-07-25 | 2007-10-15 | Hoffmann La Roche | Kombination eines mglur2 antagonists und eines ache inhibitors zur behandlung von akuten und/oder chronischen neurologischen krankheiten |
| GB0322140D0 (en) | 2003-09-22 | 2003-10-22 | Pfizer Ltd | Combinations |
| JP2007509898A (ja) | 2003-11-03 | 2007-04-19 | プロビオドルグ エージー | 神経障害治療に有用な組合せ |
| US7488736B2 (en) * | 2004-05-17 | 2009-02-10 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US20060084806A1 (en) | 2004-07-21 | 2006-04-20 | Ramasubramanian Sridharan | Processes for the preparation of imidazo[1,2-a] pyridine derivatives |
| US7407966B2 (en) * | 2004-10-07 | 2008-08-05 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US7576211B2 (en) | 2004-09-30 | 2009-08-18 | Epix Delaware, Inc. | Synthesis of thienopyridinone compounds and related intermediates |
| US7598265B2 (en) | 2004-09-30 | 2009-10-06 | Epix Delaware, Inc. | Compositions and methods for treating CNS disorders |
| EP1856075A1 (fr) | 2005-01-25 | 2007-11-21 | Epix Delaware, Inc. | Composes d'arylamine substitues et leur utilisation comme modulateurs de 5-ht6 |
| EP1965807A4 (fr) | 2005-11-23 | 2010-10-27 | Epix Delaware Inc | Composes modulateurs du recepteur s1p et utilisation associee |
| AR061637A1 (es) | 2006-06-26 | 2008-09-10 | Epix Delaware Inc | Composiciones y metodos de tratamiento de trastornos del snc |
| US20100184749A1 (en) | 2006-10-12 | 2010-07-22 | EPIX Delaware ,Inc. | Benzothiadiazine compounds and their use |
| CL2007003305A1 (es) | 2006-11-17 | 2008-07-04 | Epix Delaware Inc | Compuestos analogos de adenosina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermdades tales como fibrosis quistica, otitis media, asma, ulcera peptica, entre otras. |
-
2005
- 2005-11-10 US US11/271,019 patent/US7598265B2/en active Active
-
2006
- 2006-11-06 KR KR1020087013812A patent/KR20080067001A/ko not_active Ceased
- 2006-11-06 AU AU2006315854A patent/AU2006315854A1/en not_active Abandoned
- 2006-11-06 EA EA200801302A patent/EA200801302A1/ru unknown
- 2006-11-06 BR BRPI0618493-6A patent/BRPI0618493A2/pt not_active IP Right Cessation
- 2006-11-06 CN CNA2006800467370A patent/CN101340908A/zh active Pending
- 2006-11-06 JP JP2008540098A patent/JP2009515877A/ja active Pending
- 2006-11-06 CA CA2629312A patent/CA2629312C/fr active Active
- 2006-11-06 EP EP06827533A patent/EP1959954A2/fr not_active Ceased
- 2006-11-06 WO PCT/US2006/043140 patent/WO2007058805A2/fr not_active Ceased
- 2006-11-09 AR ARP060104925A patent/AR057887A1/es not_active Application Discontinuation
- 2006-11-09 TW TW095141449A patent/TW200735868A/zh unknown
-
2008
- 2008-04-30 IL IL191168A patent/IL191168A0/en unknown
- 2008-06-06 ZA ZA200804951A patent/ZA200804951B/xx unknown
- 2008-06-06 MA MA31013A patent/MA30037B1/fr unknown
- 2008-06-10 NO NO20082679A patent/NO20082679L/no not_active Application Discontinuation
- 2008-06-10 CR CR10062A patent/CR10062A/es not_active Application Discontinuation
-
2009
- 2009-09-30 US US12/570,510 patent/US20110195953A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MA30037B1 (fr) | 2008-12-01 |
| EA200801302A1 (ru) | 2009-02-27 |
| BRPI0618493A2 (pt) | 2011-08-30 |
| CR10062A (es) | 2009-05-14 |
| US7598265B2 (en) | 2009-10-06 |
| CN101340908A (zh) | 2009-01-07 |
| IL191168A0 (en) | 2008-12-29 |
| ZA200804951B (en) | 2009-04-29 |
| AU2006315854A1 (en) | 2007-05-24 |
| WO2007058805A2 (fr) | 2007-05-24 |
| CA2629312C (fr) | 2014-08-12 |
| JP2009515877A (ja) | 2009-04-16 |
| AR057887A1 (es) | 2007-12-26 |
| WO2007058805A3 (fr) | 2007-10-04 |
| TW200735868A (en) | 2007-10-01 |
| US20110195953A1 (en) | 2011-08-11 |
| KR20080067001A (ko) | 2008-07-17 |
| EP1959954A2 (fr) | 2008-08-27 |
| US20060234998A1 (en) | 2006-10-19 |
| CA2629312A1 (fr) | 2007-05-24 |
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