NO20084002L - Peptider og peptid derivater savel som farmasoytiske sammensetninger inneholdende det samme - Google Patents

Peptider og peptid derivater savel som farmasoytiske sammensetninger inneholdende det samme

Info

Publication number
NO20084002L
NO20084002L NO20084002A NO20084002A NO20084002L NO 20084002 L NO20084002 L NO 20084002L NO 20084002 A NO20084002 A NO 20084002A NO 20084002 A NO20084002 A NO 20084002A NO 20084002 L NO20084002 L NO 20084002L
Authority
NO
Norway
Prior art keywords
peg
denotes
residue
well
alkyl
Prior art date
Application number
NO20084002A
Other languages
English (en)
Inventor
Peter Petzelbauer
Rainer Henning
Sonja Reingruber
Original Assignee
Fibrex Medical Res & Dev Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrex Medical Res & Dev Gmbh filed Critical Fibrex Medical Res & Dev Gmbh
Publication of NO20084002L publication Critical patent/NO20084002L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/75Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Peptider og peptidderivater ifølge formel I: H2N-GHRPXIX2X3X4X5X6X7X8PX9X10X11PX12PPPX13X14X15X16GYR-X17 (I), hvori: Xl - X16 representerer en av de 20 genetisk kodede aminosyrer, X17 representerer OR1, hvor R1 = hydrogen eller (C1 - C10 - alkyl), eller NR2R3, R2 og R3 er identisk eller forskjellig og representerer hydrogen, (C1 - C10 - alkyl), eller en rest -PEG5-60K, hvori PEG-resten er linket til N-atomet via et avstandsstykke, eller en rest NH-Y-Z-PEG5-60K, hvori Y representerer en kjemisk binding eller en genetisk kodet aminosyre blant gruppen av S, C, K eller R, og Z representerer et avstandsstykke hvor en polyetylenglykol (PEG)-rest kan være linket, så vel som fysiologisk akseptable salter derav, eller hvori: X15 eller X16 representerer en aminosyre fra gruppen av C eller K, som er linket til en rest Z-PEG5-60K via heteroatomet i sidekjeden, og hvori X17 representerer OR1, hvor R1 = hydrogen eller (C1 - C10 - alkyl), eller NR2R3, R2 og R3 er identisk eller forskjellig og representerer hydrogen eller (C1 - C10 - alkyl), så vel som fysiologisk akseptable salter derav.
NO20084002A 2006-02-23 2008-09-19 Peptider og peptid derivater savel som farmasoytiske sammensetninger inneholdende det samme NO20084002L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT3012006 2006-02-23
PCT/AT2007/000095 WO2007095660A1 (en) 2006-02-23 2007-02-23 Peptides and peptide derivatives as well as pharmaceutical compositions containing the same

Publications (1)

Publication Number Publication Date
NO20084002L true NO20084002L (no) 2008-11-18

Family

ID=38042580

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084002A NO20084002L (no) 2006-02-23 2008-09-19 Peptider og peptid derivater savel som farmasoytiske sammensetninger inneholdende det samme

Country Status (15)

Country Link
US (3) US7799758B2 (no)
EP (2) EP1987062B1 (no)
JP (1) JP2009527502A (no)
KR (1) KR20090005300A (no)
CN (1) CN101389653A (no)
AT (1) ATE513853T1 (no)
AU (1) AU2007219031B2 (no)
CA (1) CA2641908A1 (no)
ES (1) ES2371038T3 (no)
IL (1) IL193435A0 (no)
MX (1) MX2008010930A (no)
NO (1) NO20084002L (no)
RU (1) RU2008137796A (no)
WO (1) WO2007095660A1 (no)
ZA (1) ZA200807028B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1691827T1 (sl) * 2004-06-25 2010-01-29 Fibrex Medical Res & Dev Gmbh Uporaba peptidov, izvedenih iz Bbeta-verige človeškega fibrinogena, za zdravljenje šoka
WO2009038729A2 (en) * 2007-09-17 2009-03-26 Regenerx Biopharmaceuticals, Inc. Compositions and methods utilizing fibrin beta chain fragments of the bbeta chain of fibrinogen
JP5410997B2 (ja) * 2008-01-31 2014-02-05 則行 川村 うつ病およびうつ状態のマーカーおよびそれを用いた検出・診断
US20090286740A1 (en) * 2008-05-15 2009-11-19 Fibrex Medical Research & Development Gmbh Peptides and derivatives thereof, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
US7884074B2 (en) 2008-05-15 2011-02-08 Ikaria Development Subsidiary Two, LLC Compounds and methods for prevention and/or treatment of inflammation using the same
US20090286725A1 (en) * 2008-05-15 2009-11-19 Fibrex Medical Research & Development Gmbh Peptides and derivatives thereof, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
US8088890B2 (en) * 2008-09-26 2012-01-03 Fibrex Medical Research & Development Gmbh Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
WO2010043444A2 (en) * 2008-10-15 2010-04-22 Fibrex Medical Research & Development Gmbh Pharmaceutical preparation for the treatment and/or prevention of ischemia/reperfusion injury and the sequels thereof
US20100152832A1 (en) * 2008-12-12 2010-06-17 Medtronic Vascular, Inc. Apparatus and Methods for Treatment of Aneurysms With Fibrin Derived Peptide B-Beta
US8841257B2 (en) * 2009-04-10 2014-09-23 Board Of Regents, The University Of Texas System Inhibitors of STAT3 and uses thereof
US12171802B2 (en) 2016-06-02 2024-12-24 University Of Maryland, Baltimore Compositions for inhibiting fibrin-VLDL receptor-dependent inflammation and methods of treatment
WO2019011879A1 (en) 2017-07-09 2019-01-17 Rainer Henning THERAPEUTIC AGENT FOR THE TREATMENT OF CAPILLARY LEAK SYNDROME
JP7429032B2 (ja) * 2019-12-24 2024-02-07 学校法人順天堂 間質性肺炎モデル非ヒト動物の作製方法
EP3912679A1 (en) 2020-05-19 2021-11-24 Johann Wolfgang Goethe-Universität Frankfurt am Main Bbeta-15-42 for the treatment of viral endothelitis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966848A (en) * 1988-02-08 1990-10-30 The General Hospital Corporation Isolation, purification, characterization, cloning and sequencing of N α-acetyltransferase
US5223421A (en) * 1989-10-25 1993-06-29 The General Hospital Corporation Identification of methionine Nα-acetyltransferase
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
GEP20033082B (en) 1991-03-15 2003-10-27 Amgen Inc Pegylation of Polypeptides
US5688489A (en) * 1995-09-15 1997-11-18 Resolution Pharmaceuticals, Inc. Non-receptor mediated imaging agents
US6323311B1 (en) * 1999-09-22 2001-11-27 University Of Utah Research Foundation Synthesis of insulin derivatives
SI1341819T1 (sl) * 2000-12-12 2006-10-31 Fibrex Medical Res & Dev Gmbh Uporaba fibrinskih/fibrinogenskih peptidov in proteinov za pripravo zdravila
DE10314329A1 (de) * 2003-03-28 2004-10-21 Zf Friedrichshafen Ag Antriebsstrang zum Antrieb eines Mobil-Fahrzeugs
EP1626983B8 (en) 2003-05-12 2010-12-22 Affymax, Inc. Novel poly (ethylene glycol) modified erythropoietin agonists and uses thereof
SI1691827T1 (sl) * 2004-06-25 2010-01-29 Fibrex Medical Res & Dev Gmbh Uporaba peptidov, izvedenih iz Bbeta-verige človeškega fibrinogena, za zdravljenje šoka
AT502987A1 (de) * 2005-12-23 2007-07-15 Fibrex Medical Res & Dev Gmbh Pharmazeutische zusammensetzung zur behandlung von hämorrhagischem schock und seinen folgeerscheinungen

Also Published As

Publication number Publication date
US20080039388A1 (en) 2008-02-14
IL193435A0 (en) 2011-08-01
EP1987062A1 (en) 2008-11-05
CA2641908A1 (en) 2007-08-30
US20100279924A1 (en) 2010-11-04
EP1987062B1 (en) 2011-06-22
MX2008010930A (es) 2008-10-29
CN101389653A (zh) 2009-03-18
ES2371038T3 (es) 2011-12-26
AU2007219031B2 (en) 2011-11-03
EP2256131A1 (en) 2010-12-01
ATE513853T1 (de) 2011-07-15
US20110098442A1 (en) 2011-04-28
ZA200807028B (en) 2009-11-25
WO2007095660A1 (en) 2007-08-30
KR20090005300A (ko) 2009-01-13
RU2008137796A (ru) 2010-03-27
US7799758B2 (en) 2010-09-21
AU2007219031A1 (en) 2007-08-30
JP2009527502A (ja) 2009-07-30

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