NO20084701L - Ny heterocyklisk forbindelse eller salt eller intermediat derav - Google Patents

Ny heterocyklisk forbindelse eller salt eller intermediat derav

Info

Publication number
NO20084701L
NO20084701L NO20084701A NO20084701A NO20084701L NO 20084701 L NO20084701 L NO 20084701L NO 20084701 A NO20084701 A NO 20084701A NO 20084701 A NO20084701 A NO 20084701A NO 20084701 L NO20084701 L NO 20084701L
Authority
NO
Norway
Prior art keywords
salt
substituted
group
heterocyclic compound
new heterocyclic
Prior art date
Application number
NO20084701A
Other languages
English (en)
Inventor
Taro Kiyoto
Junichi Ando
Tadashi Tanaka
Yasuhiro Tsutsui
Mai Yokotani
Toshiya Noguchi
Fumihito Ushiyama
Hiroki Urabe
Hiromasa Horikiri
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of NO20084701L publication Critical patent/NO20084701L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Det er beskrevet en forbindelse som er representert ved den generelle formel: hvor Rrepresenterer en arylgnippe eller heterocyklisk gruppe som kan være substituert, eller lignende; X1 representerer en C2-C4 alkylengruppe eller lignende; X2, X3 og Xrepresenterer uavhengig NH, en binding eller lignende; Xrepresenterer en lavere alkylengruppe, en binding eller lignende; Yrepresenterer en bivalent, alicyklisk hydrokarbonrest som kan være substituert, eller en bivalent alicyklisk aminrest som kan være substituert; og Z,, Z, Zog Zrepresenterer uavhengig et nitrogenatom, en gruppe som er representert ved formelen: CH, eller lignende, forutsatt at minst én av Z, Z, Zog Zrepresenterer et nitrogenatom] eller et salt derav, som er anvendelig som et antibakterielt middel.
NO20084701A 2006-05-26 2008-11-10 Ny heterocyklisk forbindelse eller salt eller intermediat derav NO20084701L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006146588 2006-05-26
PCT/JP2007/060606 WO2007138974A1 (ja) 2006-05-26 2007-05-24 新規な複素環化合物またはその塩ならびにその中間体

Publications (1)

Publication Number Publication Date
NO20084701L true NO20084701L (no) 2009-02-06

Family

ID=38778494

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084701A NO20084701L (no) 2006-05-26 2008-11-10 Ny heterocyklisk forbindelse eller salt eller intermediat derav

Country Status (17)

Country Link
US (2) US8211908B2 (no)
EP (1) EP2022793B1 (no)
JP (1) JP5171618B2 (no)
KR (1) KR101409261B1 (no)
CN (1) CN101454319B (no)
AU (1) AU2007268749B2 (no)
BR (1) BRPI0712163A2 (no)
CA (1) CA2652501C (no)
ES (1) ES2476423T3 (no)
IL (1) IL195346A (no)
MX (1) MX2008014908A (no)
NO (1) NO20084701L (no)
NZ (1) NZ573032A (no)
RU (1) RU2434868C2 (no)
SG (1) SG164384A1 (no)
WO (1) WO2007138974A1 (no)
ZA (1) ZA200809782B (no)

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MX2008014908A (es) 2006-05-26 2009-05-13 Toyama Chemical Co Ltd Compuesto heterociclico nuevo o sal del mismo e intermedio del mismo.
JP5315239B2 (ja) * 2006-07-20 2013-10-16 グラクソ グループ リミテッド Ｎ−エチルキノロンおよびｎ−エチルアザキノロンの誘導体およびアナログ
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
US20100144717A1 (en) * 2006-12-15 2010-06-10 Janelle Comita-Prevoir 2-quinolinone and 2-quinoxalinone-derivatives and their use as antibacterial agents
TW200831517A (en) * 2006-12-15 2008-08-01 Astrazeneca Ab Chemical compounds
WO2008071962A1 (en) * 2006-12-15 2008-06-19 Astrazeneca Ab Pteridines and pyrimidinopyridines as antibacterial agents
WO2008071964A1 (en) * 2006-12-15 2008-06-19 Astrazeneca Ab Naphthyridine bactericides
US8354426B2 (en) * 2007-11-26 2013-01-15 Toyama Chemical Co., Ltd. Naphthyridine derivative monohydrate and method for producing the same
JP5620636B2 (ja) * 2007-11-26 2014-11-05 富山化学工業株式会社 新規な複素環化合物またはその塩を含有する抗菌剤
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EP2341052A4 (en) * 2008-09-05 2011-10-12 Shionogi & Co RING-CONDENSED MORPHOLINE DERIVATIVITY WITH PI3K-INHIBITING EFFECT
JP5490809B2 (ja) * 2008-10-10 2014-05-14 アクテリオン ファーマシューティカルズ リミテッド オキサゾリジニル抗生物質
TW201022279A (en) * 2008-11-14 2010-06-16 Astrazeneca Ab Chemical compounds
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AR076222A1 (es) 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
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TW201309689A (zh) 2011-02-07 2013-03-01 Daiichi Sankyo Co Ltd 含胺基之吡咯啶酮衍生物
US8470884B2 (en) 2011-11-09 2013-06-25 Hoffmann-La Roche Inc. Alkenyl naphthylacetic acids
TW201326180A (zh) 2011-11-30 2013-07-01 Actelion Pharmaceuticals Ltd ３，７－二取代八氫－２Ｈ－吡啶并［４，３－ｅ］［１，３］□嗪－２－酮抗生素
WO2014151682A1 (en) * 2013-03-14 2014-09-25 Icahn School Of Medicine At Mount Sinai Pyrimidine compounds as kinase inhibitors
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
WO2019113419A1 (en) * 2017-12-08 2019-06-13 The Rockefeller University Pyrano[3,4-b]pyrazine kappa opioid receptor ligands for treating addiction, pruritus, pain, and inflammation
JP2021511364A (ja) * 2018-01-29 2021-05-06 カディラ ヘルスケア リミティド 抗菌剤として有用な複素環式化合物
CN109678793B (zh) * 2019-01-12 2020-08-04 上海卡洛化学有限公司 一种5-氟-3-氨基吡啶的制备方法
WO2026130518A1 (zh) * 2024-12-20 2026-06-25 江苏恒瑞医药股份有限公司 一种萘啶酮类衍生物及其制备方法

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MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
EP2468743A1 (en) 2005-06-24 2012-06-27 Toyama Chemical Co., Ltd. Nitrogen-containing bicyclic compounds useful as antibacterial agents
MX2008014908A (es) 2006-05-26 2009-05-13 Toyama Chemical Co Ltd Compuesto heterociclico nuevo o sal del mismo e intermedio del mismo.
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
WO2008071964A1 (en) 2006-12-15 2008-06-19 Astrazeneca Ab Naphthyridine bactericides
WO2008071962A1 (en) 2006-12-15 2008-06-19 Astrazeneca Ab Pteridines and pyrimidinopyridines as antibacterial agents
WO2009001126A1 (en) 2007-06-27 2008-12-31 Astrazeneca Ab Substituted piperidine derivatives and their use as antibaterial agents
US8354426B2 (en) 2007-11-26 2013-01-15 Toyama Chemical Co., Ltd. Naphthyridine derivative monohydrate and method for producing the same

Also Published As

Publication number Publication date
JPWO2007138974A1 (ja) 2009-10-08
AU2007268749B2 (en) 2012-07-26
US8367831B2 (en) 2013-02-05
US20120226035A1 (en) 2012-09-06
RU2434868C2 (ru) 2011-11-27
SG164384A1 (en) 2010-09-29
CA2652501C (en) 2014-07-08
EP2022793A4 (en) 2010-09-08
IL195346A (en) 2013-02-28
BRPI0712163A2 (pt) 2012-03-13
IL195346A0 (en) 2009-08-03
CN101454319B (zh) 2012-06-27
EP2022793B1 (en) 2014-06-04
US20090198063A1 (en) 2009-08-06
AU2007268749A1 (en) 2007-12-06
EP2022793A1 (en) 2009-02-11
ES2476423T3 (es) 2014-07-14
JP5171618B2 (ja) 2013-03-27
US8211908B2 (en) 2012-07-03
CA2652501A1 (en) 2007-12-06
KR20090018976A (ko) 2009-02-24
HK1133874A1 (en) 2010-04-09
RU2008151754A (ru) 2010-07-10
NZ573032A (en) 2010-12-24
ZA200809782B (en) 2010-02-24
CN101454319A (zh) 2009-06-10
WO2007138974A1 (ja) 2007-12-06
MX2008014908A (es) 2009-05-13
KR101409261B1 (ko) 2014-06-18

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