NO20084835L - Culture method for obtaining a clone population of antigen-specific B cells - Google Patents
Culture method for obtaining a clone population of antigen-specific B cellsInfo
- Publication number
- NO20084835L NO20084835L NO20084835A NO20084835A NO20084835L NO 20084835 L NO20084835 L NO 20084835L NO 20084835 A NO20084835 A NO 20084835A NO 20084835 A NO20084835 A NO 20084835A NO 20084835 L NO20084835 L NO 20084835L
- Authority
- NO
- Norway
- Prior art keywords
- antigen
- cells
- obtaining
- specific
- culture method
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
Det beskrives fremgangsmåter for isolering av antigenspesifikke celler og fremstilling av antistoffer fra disse.Methods for isolating antigen-specific cells and producing antibodies therefrom are described.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80141206P | 2006-05-19 | 2006-05-19 | |
| PCT/US2007/011980 WO2008045140A1 (en) | 2006-05-19 | 2007-05-21 | Culture method for obtaining a clonal population of antigen-specific b cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20084835L true NO20084835L (en) | 2009-02-16 |
Family
ID=39283142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20084835A NO20084835L (en) | 2006-05-19 | 2008-11-18 | Culture method for obtaining a clone population of antigen-specific B cells |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20070269868A1 (en) |
| EP (1) | EP2021463B1 (en) |
| JP (1) | JP5607357B2 (en) |
| CN (1) | CN101600793B (en) |
| AU (1) | AU2007307324B2 (en) |
| CA (1) | CA2652392C (en) |
| DK (1) | DK2021463T3 (en) |
| IL (1) | IL195285A (en) |
| MX (1) | MX2008014692A (en) |
| NO (1) | NO20084835L (en) |
| NZ (1) | NZ572807A (en) |
| WO (1) | WO2008045140A1 (en) |
Families Citing this family (68)
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| DK2164514T3 (en) | 2007-05-21 | 2017-02-27 | Alderbio Holdings Llc | Antibodies to IL-6 and its use |
| US8404235B2 (en) | 2007-05-21 | 2013-03-26 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
| US9701747B2 (en) | 2007-05-21 | 2017-07-11 | Alderbio Holdings Llc | Method of improving patient survivability and quality of life by anti-IL-6 antibody administration |
| US8062864B2 (en) | 2007-05-21 | 2011-11-22 | Alderbio Holdings Llc | Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies |
| US8178101B2 (en) | 2007-05-21 | 2012-05-15 | Alderbio Holdings Inc. | Use of anti-IL-6 antibodies having specific binding properties to treat cachexia |
| US7906117B2 (en) | 2007-05-21 | 2011-03-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever |
| US8252286B2 (en) | 2007-05-21 | 2012-08-28 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
| US9212223B2 (en) | 2008-11-25 | 2015-12-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
| US9452227B2 (en) | 2008-11-25 | 2016-09-27 | Alderbio Holdings Llc | Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments |
| US8420089B2 (en) | 2008-11-25 | 2013-04-16 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
| US8323649B2 (en) | 2008-11-25 | 2012-12-04 | Alderbio Holdings Llc | Antibodies to IL-6 and use thereof |
| US8992920B2 (en) | 2008-11-25 | 2015-03-31 | Alderbio Holdings Llc | Anti-IL-6 antibodies for the treatment of arthritis |
| KR20110112307A (en) * | 2008-11-25 | 2011-10-12 | 앨더 바이오파마슈티컬즈, 인코포레이티드 | IL-6 antagonist that raises albumin and / or lowers Crp |
| US8337847B2 (en) | 2008-11-25 | 2012-12-25 | Alderbio Holdings Llc | Methods of treating anemia using anti-IL-6 antibodies |
| US9079942B2 (en) * | 2009-02-09 | 2015-07-14 | Epitomics, Inc. | CDR-anchored amplification method |
| US20100317539A1 (en) * | 2009-06-12 | 2010-12-16 | Guo-Liang Yu | Library of Engineered-Antibody Producing Cells |
| KR101790802B1 (en) | 2009-09-03 | 2017-10-27 | 머크 샤프 앤드 돔 코포레이션 | Anti-gitr antibodies |
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| CN102740888B (en) | 2009-11-24 | 2016-10-12 | 奥尔德生物制药公司 | IL-6 antibody and application thereof |
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| TWI667257B (en) | 2010-03-30 | 2019-08-01 | 中外製藥股份有限公司 | Antibodies with modified affinity to fcrn that promote antigen clearance |
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| CA2818813C (en) | 2010-11-23 | 2020-10-06 | Alder Biopharmaceuticals, Inc. | Anti-il-6 antibodies for the treatment of oral mucositis |
| EP2646468B1 (en) | 2010-12-01 | 2018-07-25 | AlderBio Holdings LLC | Anti-ngf compositions and use thereof |
| JP5963746B2 (en) | 2011-03-30 | 2016-08-03 | 国立大学法人富山大学 | Plasma cell or plasmablast selection method, target antigen-specific antibody production method, novel monoclonal antibody |
| TWI705825B (en) | 2011-05-20 | 2020-10-01 | 美商艾爾德生物控股有限責任公司 | Use of anti-cgrp or anti-cgrp-r antibodies or antibody fragments to treat or prevent chronic and acute forms of diarrhea |
| PE20141787A1 (en) | 2011-05-20 | 2014-12-07 | Alderbio Holdings Llc | ANTI-CGRP COMPOSITIONS AND USE OF THEM |
| CN107827982B (en) | 2011-05-20 | 2021-07-06 | H.伦德贝克公司 | Use of anti-CGRP antibodies and antibody fragments for the prevention or inhibition of photophobia or photophobia in a subject in need thereof |
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| CN104903349B (en) | 2012-11-08 | 2018-10-19 | 十一生物治疗股份有限公司 | IL-6 antagonists and its application |
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| JP2016506974A (en) * | 2013-02-15 | 2016-03-07 | エスバテック − ア ノバルティスカンパニー エルエルシー | Acceptor framework for CDR grafting |
| WO2014153166A2 (en) * | 2013-03-14 | 2014-09-25 | Alder Biopharmaceuticals, Inc. | Therapeutic use of antibodies to hgf |
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| TWI670279B (en) | 2013-03-15 | 2019-09-01 | Alder Biopharmaceuticals, Inc. | Antibody purification and purity monitoring |
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| CN104232577B (en) * | 2013-06-20 | 2017-12-01 | 中国人民解放军军事医学科学院基础医学研究所 | A kind of method for obtaining autoreactivity B cell |
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| US11125757B2 (en) * | 2017-05-26 | 2021-09-21 | Emory University | Methods of culturing and characterizing antibody secreting cells |
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| JP2021525070A (en) * | 2018-05-18 | 2021-09-24 | チャン ザッカーバーグ バイオハブ, インコーポレイテッド | Methods for Isolating Human-Derived Allergen-Specific Antibodies and Their Use |
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| JP2023106635A (en) | 2020-04-17 | 2023-08-02 | 中外製薬株式会社 | Bispecific Antigen Binding Molecules and Compositions Associated Therewith, Uses, Kits, and Methods for the Manufacture of Compositions |
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| US20070092943A1 (en) * | 2005-09-28 | 2007-04-26 | The University Of Chicago | Versatile vectors for expression of foreign proteins in photosynthetic bacteria |
-
2007
- 2007-05-21 EP EP07861311.4A patent/EP2021463B1/en not_active Revoked
- 2007-05-21 NZ NZ572807A patent/NZ572807A/en not_active IP Right Cessation
- 2007-05-21 DK DK07861311.4T patent/DK2021463T3/en active
- 2007-05-21 WO PCT/US2007/011980 patent/WO2008045140A1/en not_active Ceased
- 2007-05-21 JP JP2009512060A patent/JP5607357B2/en not_active Expired - Fee Related
- 2007-05-21 CA CA2652392A patent/CA2652392C/en not_active Expired - Fee Related
- 2007-05-21 US US11/802,235 patent/US20070269868A1/en not_active Abandoned
- 2007-05-21 AU AU2007307324A patent/AU2007307324B2/en not_active Ceased
- 2007-05-21 CN CN200780027028.2A patent/CN101600793B/en not_active Expired - Fee Related
- 2007-05-21 MX MX2008014692A patent/MX2008014692A/en active IP Right Grant
-
2008
- 2008-11-13 IL IL195285A patent/IL195285A/en active IP Right Grant
- 2008-11-18 NO NO20084835A patent/NO20084835L/en unknown
-
2011
- 2011-08-08 US US13/204,915 patent/US20120141982A1/en not_active Abandoned
-
2013
- 2013-04-12 US US13/861,518 patent/US20130316353A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101600793A (en) | 2009-12-09 |
| IL195285A0 (en) | 2011-08-01 |
| IL195285A (en) | 2012-07-31 |
| WO2008045140A1 (en) | 2008-04-17 |
| DK2021463T3 (en) | 2017-01-16 |
| EP2021463B1 (en) | 2016-11-23 |
| AU2007307324B2 (en) | 2013-08-15 |
| US20070269868A1 (en) | 2007-11-22 |
| CA2652392C (en) | 2017-10-10 |
| US20130316353A1 (en) | 2013-11-28 |
| EP2021463A1 (en) | 2009-02-11 |
| EP2021463A4 (en) | 2009-09-02 |
| CN101600793B (en) | 2013-06-26 |
| JP5607357B2 (en) | 2014-10-15 |
| AU2007307324A1 (en) | 2008-04-17 |
| JP2009537176A (en) | 2009-10-29 |
| US20120141982A1 (en) | 2012-06-07 |
| CA2652392A1 (en) | 2008-04-17 |
| NZ572807A (en) | 2011-10-28 |
| MX2008014692A (en) | 2009-08-18 |
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