NO20085212L - Nye pyridinanaloger - Google Patents

Nye pyridinanaloger

Info

Publication number
NO20085212L
NO20085212L NO20085212A NO20085212A NO20085212L NO 20085212 L NO20085212 L NO 20085212L NO 20085212 A NO20085212 A NO 20085212A NO 20085212 A NO20085212 A NO 20085212A NO 20085212 L NO20085212 L NO 20085212L
Authority
NO
Norway
Prior art keywords
pyridine analogs
new pyridine
formula
analogs
new
Prior art date
Application number
NO20085212A
Other languages
English (en)
Inventor
Kay Brickmann
Fabrizio Giordanetto
Fredrik Zetterberg
Johan Johansson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20085212L publication Critical patent/NO20085212L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Foreliggende oppfinnelse angår visse ny pyridinanaloger med formel ( I ), Formel ( I ) fremgangsmåte for fremstilling av slike forbindelser, deres anvendelse som P2Y12-inhibitorer og som anti-trombotiske midler og lignende, anvendelse av disse som medikamenter i kardiovaskulære sykdommer samt farmasøytiske preparater inneholdende disse.
NO20085212A 2006-07-04 2008-12-15 Nye pyridinanaloger NO20085212L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0601466 2006-07-04
PCT/SE2007/000642 WO2008004942A1 (en) 2006-07-04 2007-07-02 New pyridine analogues

Publications (1)

Publication Number Publication Date
NO20085212L true NO20085212L (no) 2009-01-12

Family

ID=38894821

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20085212A NO20085212L (no) 2006-07-04 2008-12-15 Nye pyridinanaloger

Country Status (13)

Country Link
US (2) US20080032992A1 (no)
EP (1) EP2041115A4 (no)
JP (1) JP2009542642A (no)
KR (1) KR20090036573A (no)
CN (1) CN101511815A (no)
AU (1) AU2007270082A1 (no)
BR (1) BRPI0713957A2 (no)
CA (1) CA2655629A1 (no)
IL (1) IL195980A0 (no)
MX (1) MX2008016557A (no)
NO (1) NO20085212L (no)
WO (1) WO2008004942A1 (no)
ZA (1) ZA200810646B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006073361A1 (en) * 2005-01-06 2006-07-13 Astrazeneca Ab Novel pyridine compounds
US20080312208A1 (en) * 2005-07-13 2008-12-18 Astrazeneca Ab Pyridine Analogues
TW200815426A (en) * 2006-06-28 2008-04-01 Astrazeneca Ab New pyridine analogues II 333
AU2007270083A1 (en) * 2006-07-04 2008-01-10 Astrazeneca Ab New pyridine analogues
TW200811133A (en) * 2006-07-04 2008-03-01 Astrazeneca Ab New pyridine analogues III 334
CN101511815A (zh) * 2006-07-04 2009-08-19 阿斯利康(瑞典)有限公司 新型吡啶类似物
WO2008004941A1 (en) * 2006-07-04 2008-01-10 Astrazeneca Ab New pyridine analogues
UY30866A1 (es) * 2007-01-12 2008-09-02 Astrazeneca Ab Nuevos compuestos de piridina, composiciones farmacéuticas conteniéndolos y aplicaciones (519)
UY30868A1 (es) * 2007-01-12 2008-09-02 Astrazeneca Ab Nuevos compuestos de piridina, composiciones farmacéuticas conteniéndolas y aplicaciones.
UY30867A1 (es) * 2007-01-12 2008-09-02 Astrazeneca Ab Nuevos analogos de piridina vii 543
US20090018166A1 (en) * 2007-07-13 2009-01-15 Astrazeneca Ab New Pyridine Analogues X 161
WO2010005385A1 (en) * 2008-07-07 2010-01-14 Astrazeneca Ab 2-amino-6-alkyl substituted pyridine derivatives useful as p2y12 inhibitors 308
EP2750676B1 (en) 2011-08-30 2018-01-10 University of Utah Research Foundation Methods and compositions for treating nephrogenic diabetes insipidus
CN110636846B (zh) 2017-05-17 2023-05-16 艾库斯生物科学有限公司 用于治疗癌症相关疾病的喹唑啉吡唑衍生物
CR20200464A (es) 2018-03-08 2021-04-14 Incyte Corp Compuestos diólicos de aminopirazina como inhibidores de pi3k-y
WO2020010003A1 (en) 2018-07-02 2020-01-09 Incyte Corporation AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156758A (en) * 1999-09-08 2000-12-05 Isis Pharmaceuticals, Inc. Antibacterial quinazoline compounds
US6906063B2 (en) * 2000-02-04 2005-06-14 Portola Pharmaceuticals, Inc. Platelet ADP receptor inhibitors
WO2001057037A1 (en) * 2000-02-04 2001-08-09 Cor Therapeutics, Inc. Platelet adp receptor inhibitors
US7018985B1 (en) * 2000-08-21 2006-03-28 Inspire Pharmaceuticals, Inc. Composition and method for inhibiting platelet aggregation
US7452870B2 (en) * 2000-08-21 2008-11-18 Inspire Pharmaceuticals, Inc. Drug-eluting stents coated with P2Y12 receptor antagonist compound
US7132408B2 (en) * 2000-08-21 2006-11-07 Inspire Pharmaceuticals, Inc. Composition and method for inhibiting platelet aggregation
FR2820057A1 (fr) * 2001-01-30 2002-08-02 Ct De Transfert De Technologie Membrane pour chambre d'encapsulation de cellules produisant au moins une substance biologiquement active et organe bio-artificiel comprenant une telle membrane
KR20060113699A (ko) * 2003-10-03 2006-11-02 포톨라 파마슈티컬스, 인코포레이티드 치환된 이소퀴놀리논
US7504497B2 (en) * 2003-10-21 2009-03-17 Inspire Pharmaceuticals, Inc. Orally bioavailable compounds and methods for inhibiting platelet aggregation
US7335648B2 (en) * 2003-10-21 2008-02-26 Inspire Pharmaceuticals, Inc. Non-nucleotide composition and method for inhibiting platelet aggregation
US7749981B2 (en) * 2003-10-21 2010-07-06 Inspire Pharmaceuticals, Inc. Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound
WO2006012226A2 (en) * 2004-06-24 2006-02-02 Incyte Corporation N-substituted piperidines and their use as pharmaceuticals
WO2006073361A1 (en) * 2005-01-06 2006-07-13 Astrazeneca Ab Novel pyridine compounds
CN101511815A (zh) * 2006-07-04 2009-08-19 阿斯利康(瑞典)有限公司 新型吡啶类似物
WO2008004941A1 (en) * 2006-07-04 2008-01-10 Astrazeneca Ab New pyridine analogues
AU2007270083A1 (en) * 2006-07-04 2008-01-10 Astrazeneca Ab New pyridine analogues
TW200817375A (en) * 2006-07-21 2008-04-16 Irm Llc Compounds and compositions as ITPKB inhibitors

Also Published As

Publication number Publication date
JP2009542642A (ja) 2009-12-03
ZA200810646B (en) 2010-05-26
CA2655629A1 (en) 2008-01-10
IL195980A0 (en) 2009-09-01
US20080032992A1 (en) 2008-02-07
US20090318464A1 (en) 2009-12-24
CN101511815A (zh) 2009-08-19
BRPI0713957A2 (pt) 2013-04-02
MX2008016557A (es) 2009-02-06
WO2008004942A1 (en) 2008-01-10
AU2007270082A1 (en) 2008-01-10
EP2041115A4 (en) 2010-07-07
US20110059981A9 (en) 2011-03-10
EP2041115A1 (en) 2009-04-01
KR20090036573A (ko) 2009-04-14

Similar Documents

Publication Publication Date Title
NO20085218L (no) Nye pyridinanaloger
NO20085214L (no) Nye pyridinanaloger
NO20073791L (no) Pyrazolylaminopyridinderivater anvendbare som kinaseinhibitorer
NO20073101L (no) Nye pyridinforbindelser
NO20076682L (no) Nye pyridinanaloger
NO20090628L (no) Pyridizinon derivativater
NO20083427L (no) Cystoksiske midler omfattende nye tomaymycinderivater og deres terapeutiske anvendelse
NO20085213L (no) Nye pyridinanaloger
NO20074592L (no) Acetylenyl-pyrazolo-pyrimidinderivater som mGluR2-antagonister
NO20092723L (no) Indazolylester og amidderivater for behandling av gluccocorticoid reseptormedierte sykdommer
NO20070224L (no) 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
NO20074258L (no) Pyridin-2-karboksamidderivater som MGLUR5 antagonister
NO20090835L (no) Nye HIV-reverstranskriptaseinhibitorer
NO20076059L (no) 2,4-Diamino-pyrimidiner anvendt som aurorainhibitorer
NO20083919L (no) Pyridin- og pyrimidinderivater som mGluR2-antagonister
NO20091553L (no) Fenylderivater og deres anvendelse som immunmodulatorer
EA201001683A1 (ru) Производные фенил- или пиридинилзамещенных индазолов
NO20071504L (no) Pyrimidinderivanter.
NO20092412L (no) Hydantoinderivater anvendes som MMP-inhibitorer
NO20063449L (no) Substituerte heterocykler og deres anvendelse
NO20084186L (no) Nye aminer
NO20081001L (no) Derivater av karboksamid som antagonister for muskarinisk reseptor
NO20076448L (no) Novel piperidine carboxylic acid amide derivatives
NO20083738L (no) Sekundaere aminer som renininhibitorer
EA201071269A1 (ru) 3,4-замещенные пиперидиновые производные в качестве ингибиторов ренина

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application