NO20090163L - Kombinasjonsfremstillinger innbefattende en darlig vannopploselig aktiv substans - Google Patents
Kombinasjonsfremstillinger innbefattende en darlig vannopploselig aktiv substansInfo
- Publication number
- NO20090163L NO20090163L NO20090163A NO20090163A NO20090163L NO 20090163 L NO20090163 L NO 20090163L NO 20090163 A NO20090163 A NO 20090163A NO 20090163 A NO20090163 A NO 20090163A NO 20090163 L NO20090163 L NO 20090163L
- Authority
- NO
- Norway
- Prior art keywords
- active substance
- poorly water
- soluble active
- preparations including
- combination preparations
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- NTQSYIWTDXTRGG-UHFFFAOYSA-N 2-(1-benzazepin-1-yl)acetic acid Chemical group OC(=O)CN1C=CC=CC2=CC=CC=C12 NTQSYIWTDXTRGG-UHFFFAOYSA-N 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Oppfinnelsen er relatert til en oral sammensetning av benzazepin-1-eddiksyrederivater omfattende a) nevnte aktive forbindelse i en mengde på mellom I 0 og 65 % av den totale vekten av formuleringen; b) minst 10 vekt-% av en alkalisk forbindelse eller en blanding av alkaliske forbindelser; c) omfatter eventuelt hjelpematerialer i en mengde på mellom I% og 45 % av den totale vekten av formuleringen. Oppfinnelsen er videre relatert til den ovenfor definerte orale sammensetningen omfattende natriumkarbonat med en spesifikk partikkelstørrelse og/eller overflateareal som alkalisk forbindelse.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81407606P | 2006-06-16 | 2006-06-16 | |
| EP06115582 | 2006-06-16 | ||
| PCT/EP2007/055937 WO2007144418A1 (en) | 2006-06-16 | 2007-06-15 | Oral pharmaceutical composition of a poorly water-soluble active substance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20090163L true NO20090163L (no) | 2009-01-14 |
Family
ID=38475902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20090163A NO20090163L (no) | 2006-06-16 | 2009-01-12 | Kombinasjonsfremstillinger innbefattende en darlig vannopploselig aktiv substans |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP2034967B1 (no) |
| JP (1) | JP2009539940A (no) |
| KR (1) | KR20090032085A (no) |
| AT (1) | ATE509620T1 (no) |
| AU (1) | AU2007259252A1 (no) |
| CA (1) | CA2654111A1 (no) |
| EA (1) | EA014898B1 (no) |
| IL (1) | IL195531A0 (no) |
| NO (1) | NO20090163L (no) |
| WO (1) | WO2007144418A1 (no) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2788289B1 (de) * | 2011-12-09 | 2019-07-31 | Merck Patent GmbH | Porenarmes, wasserfreies natriumcarbonat |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR038681A1 (es) * | 2002-02-14 | 2005-01-26 | Solvay Pharm Bv | Formulacion oral de solucion solida de una sustancia activa pobremente soluble en agua |
| WO2004062692A1 (en) * | 2003-01-13 | 2004-07-29 | Solvay Pharmaceuticals B.V. | Formulation of poorly water-soluble active substances |
| TW200633713A (en) * | 2004-12-23 | 2006-10-01 | Solvay Pharm Bv | Oral immediate release formulation of a poorly water-soluble active substance |
| WO2007054975A1 (en) * | 2005-11-08 | 2007-05-18 | Panacea Biotec Ltd | Pharmaceutical compositions for the treatment of cardiovascular and other associated disorders |
-
2007
- 2007-06-15 WO PCT/EP2007/055937 patent/WO2007144418A1/en not_active Ceased
- 2007-06-15 AT AT07730181T patent/ATE509620T1/de not_active IP Right Cessation
- 2007-06-15 KR KR1020097000922A patent/KR20090032085A/ko not_active Withdrawn
- 2007-06-15 AU AU2007259252A patent/AU2007259252A1/en not_active Abandoned
- 2007-06-15 EP EP07730181A patent/EP2034967B1/en active Active
- 2007-06-15 EA EA200970020A patent/EA014898B1/ru not_active IP Right Cessation
- 2007-06-15 CA CA002654111A patent/CA2654111A1/en not_active Abandoned
- 2007-06-15 JP JP2009514807A patent/JP2009539940A/ja not_active Withdrawn
-
2008
- 2008-11-26 IL IL195531A patent/IL195531A0/en unknown
-
2009
- 2009-01-12 NO NO20090163A patent/NO20090163L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007144418A1 (en) | 2007-12-21 |
| EP2034967A1 (en) | 2009-03-18 |
| CA2654111A1 (en) | 2007-12-21 |
| KR20090032085A (ko) | 2009-03-31 |
| EA014898B1 (ru) | 2011-02-28 |
| EP2034967B1 (en) | 2011-05-18 |
| IL195531A0 (en) | 2009-09-01 |
| EA200970020A1 (ru) | 2009-06-30 |
| AU2007259252A1 (en) | 2007-12-21 |
| JP2009539940A (ja) | 2009-11-19 |
| ATE509620T1 (de) | 2011-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |