NO20090214L - Proteinkinase C aktivitetsforsterker inneholdende alkyleterderivat eller et salt av denne - Google Patents

Proteinkinase C aktivitetsforsterker inneholdende alkyleterderivat eller et salt av denne

Info

Publication number
NO20090214L
NO20090214L NO20090214A NO20090214A NO20090214L NO 20090214 L NO20090214 L NO 20090214L NO 20090214 A NO20090214 A NO 20090214A NO 20090214 A NO20090214 A NO 20090214A NO 20090214 L NO20090214 L NO 20090214L
Authority
NO
Norway
Prior art keywords
group
protein kinase
salt
ether derivative
alkyl ether
Prior art date
Application number
NO20090214A
Other languages
English (en)
Inventor
Tetsuo Fukushima
Akiko Takagi
Nobuo Terashima
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of NO20090214L publication Critical patent/NO20090214L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Beskrevet er en proteinkinase C forsterker karakterisert ved at den inneholder et benzotiofenalkyleterderivat representert ved den generelle formel nedenfor eller et salt derav. (I formelen, R1 og R2 kan være like eller forskjellige og representerer én eller flere grupper valgt fra et hydrogenatom, et halogenatom, en alkylgruppe, en arylgruppe, en aralkylgruppe, en alkoksygruppe, en aryloksygruppe, en alkenylgruppe, en aminogruppe, en heterocyklisk gruppe, en eventuelt beskyttet aminogruppe, en hydroksylgruppe, en karboksylgruppe, en oksogruppe og lignende; R3 representerer en alkylaminogruppe, en aminogruppe, en hydroksylgruppe eller lignende; og m og n kan være like eller forskjellige og representerer et helt tall på 1-6.) Denne proteinkinase C forsterker er anvendelige for behandling eller forebygging av forskjellige sykdommer forbundet med proteinkinase C.
NO20090214A 2006-08-04 2009-01-14 Proteinkinase C aktivitetsforsterker inneholdende alkyleterderivat eller et salt av denne NO20090214L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006212722 2006-08-04
PCT/JP2007/065165 WO2008016107A1 (en) 2006-08-04 2007-08-02 Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof

Publications (1)

Publication Number Publication Date
NO20090214L true NO20090214L (no) 2009-01-30

Family

ID=38997281

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090214A NO20090214L (no) 2006-08-04 2009-01-14 Proteinkinase C aktivitetsforsterker inneholdende alkyleterderivat eller et salt av denne

Country Status (22)

Country Link
US (2) US8173633B2 (no)
EP (1) EP2048145B9 (no)
JP (1) JP5255441B2 (no)
KR (1) KR20090038471A (no)
CN (1) CN101501026B (no)
AT (1) ATE491705T1 (no)
AU (1) AU2007279673B2 (no)
BR (1) BRPI0715056A2 (no)
CA (1) CA2659835A1 (no)
CY (1) CY1111691T1 (no)
DE (1) DE602007011281D1 (no)
DK (1) DK2048145T3 (no)
ES (1) ES2355768T3 (no)
IL (1) IL196754A0 (no)
MX (1) MX2009001255A (no)
NO (1) NO20090214L (no)
NZ (1) NZ574551A (no)
PL (1) PL2048145T3 (no)
PT (1) PT2048145E (no)
SI (1) SI2048145T1 (no)
WO (1) WO2008016107A1 (no)
ZA (1) ZA200900743B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0213393B8 (pt) 2001-10-19 2021-05-25 Fujifilm Toyama Chemical Co Ltd derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica
CA2659835A1 (en) * 2006-08-04 2008-02-07 Toyama Chemical Co., Ltd. Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof
MX2010012787A (es) 2008-05-28 2011-02-24 Toyama Chemical Co Ltd Nuevo derivado de oxido de benzotiofeno y sal del mismo.
CN103917529B (zh) 2011-11-11 2016-08-17 辉瑞大药厂 2-硫代嘧啶酮类
BR112014020434B1 (pt) * 2012-02-22 2021-10-13 Fujifilm Toyama Chemical Co., Ltd. Composição farmacêutica sólida
US10238632B2 (en) 2015-06-11 2019-03-26 Fujifilm Toyama Chemical Co., Ltd. Sigma receptor-binding agent
CA3009152C (en) * 2015-12-25 2023-08-15 Toyama Chemical Co., Ltd. Tablet comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salt thereof
JP7057286B2 (ja) * 2016-12-28 2022-04-19 富士フイルム富山化学株式会社 医薬組成物
CN110121342A (zh) * 2016-12-28 2019-08-13 富士胶片富山化学株式会社 医药组合物
US20190343796A1 (en) * 2016-12-28 2019-11-14 Fujifilm Toyama Chemical Co., Ltd. Composition for external use
US11234962B2 (en) 2016-12-28 2022-02-01 Fujifilm Toyama Chemical Co., Ltd. Pharmaceutical composition and method of manufacturing the same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09507846A (ja) * 1993-12-30 1997-08-12 スミスクライン・ビーチャム・コーポレイション フェニルメチルヘキサンアミドおよびその使用
KR20020067937A (ko) * 2000-01-26 2002-08-24 오노 야꾸힝 고교 가부시키가이샤 벤젠 축합 헤테로환 유도체 및 그 유도체를 유효성분으로서 함유하는 약제
JP4303435B2 (ja) * 2001-02-26 2009-07-29 富山化学工業株式会社 ミトコンドリア機能賦活剤
BRPI0213393B8 (pt) * 2001-10-19 2021-05-25 Fujifilm Toyama Chemical Co Ltd derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica
US6825229B2 (en) * 2002-03-07 2004-11-30 Blanchette Rockefeller Neurosciences Institute Methods for Alzheimer's Disease treatment and cognitive enhancement
HUE041842T2 (hu) * 2002-06-14 2019-05-28 Toyama Chemical Co Ltd Gyógyászati készítmény agymûködés javítására
ES2625429T3 (es) * 2003-01-23 2017-07-19 Esperion Therapeutics Inc. Compuestos de hidroxilo y composiciones para el control del colesterol y utilizaciones correspondientes
ES2391273T3 (es) * 2003-04-17 2012-11-23 Toyama Chemical Co., Ltd. Agente preventivo/curativo para enfermedades del nervio retiniano que contiene derivados de éter alquílico o sus sales
SE529122C2 (sv) * 2004-09-24 2007-05-02 Jokab Safety Ab Skyddsanordning för områdesbegränsning och övervakning
SI2248809T1 (sl) * 2005-03-28 2012-09-28 Toyama Chemical Co Ltd Alkil-3-(2-(benzo(b)tiofen-5-il)-etoksi)-propanoati kot vmesniki v proizvodnji derivatov azetidin-3-ola
JP4902247B2 (ja) * 2005-04-08 2012-03-21 富山化学工業株式会社 2−(1−ベンゾチオフェン−5−イル)エタノールの新規製造法およびその中間体
CA2648898C (en) * 2006-04-26 2015-01-20 Toyama Chemical Co., Ltd. Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof
CA2659835A1 (en) * 2006-08-04 2008-02-07 Toyama Chemical Co., Ltd. Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof

Also Published As

Publication number Publication date
EP2048145B9 (en) 2011-05-04
DE602007011281D1 (de) 2011-01-27
US20110245228A1 (en) 2011-10-06
CN101501026B (zh) 2012-04-04
EP2048145A1 (en) 2009-04-15
KR20090038471A (ko) 2009-04-20
PT2048145E (pt) 2011-01-14
US8173633B2 (en) 2012-05-08
EP2048145A4 (en) 2009-09-09
WO2008016107A1 (en) 2008-02-07
JP5255441B2 (ja) 2013-08-07
NZ574551A (en) 2012-03-30
ZA200900743B (en) 2010-05-26
SI2048145T1 (sl) 2011-04-29
JPWO2008016107A1 (ja) 2009-12-24
ATE491705T1 (de) 2011-01-15
MX2009001255A (es) 2009-06-12
IL196754A0 (en) 2009-11-18
EP2048145B1 (en) 2010-12-15
CA2659835A1 (en) 2008-02-07
DK2048145T3 (da) 2011-04-04
PL2048145T3 (pl) 2011-09-30
AU2007279673A1 (en) 2008-02-07
AU2007279673B2 (en) 2012-04-19
US20100184997A1 (en) 2010-07-22
BRPI0715056A2 (pt) 2013-05-28
CY1111691T1 (el) 2015-10-07
CN101501026A (zh) 2009-08-05
ES2355768T3 (es) 2011-03-30

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