NO20090862L - 2-fenyl-indoler som prostaglandin D2-reseptorantagonister - Google Patents

2-fenyl-indoler som prostaglandin D2-reseptorantagonister

Info

Publication number: NO20090862L
Authority: NO; Norway
Prior art keywords: urticari; itching; inflammation; allergic; diseases
Prior art date: 2006-07-25

Application number

NO20090862A

Other languages

English (en)

Norwegian (no)

Inventor

Zhaoxia Yang

Stephan Reiling

Thaddeus R Nieduzak

Rose M Mathew

Sharon Jackson

Keith J Harris

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-07-25

Filing date

2009-02-24

Publication date

2009-02-24

2009-02-24 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2009-02-24 Publication of NO20090862L publication Critical patent/NO20090862L/no

Links

KLLLJCACIRKBDT-UHFFFAOYSA-N 2-phenyl-1H-indole Chemical class N1C2=CC=CC=C2C=C1C1=CC=CC=C1 KLLLJCACIRKBDT-UHFFFAOYSA-N 0.000 title 1
102000009389 Prostaglandin D receptors Human genes 0.000 title 1
108050000258 Prostaglandin D receptors Proteins 0.000 title 1
239000002464 receptor antagonist Substances 0.000 title 1
229940044551 receptor antagonist Drugs 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 4
201000004624 Dermatitis Diseases 0.000 abstract 2
206010061218 Inflammation Diseases 0.000 abstract 2
208000003251 Pruritus Diseases 0.000 abstract 2
201000010099 disease Diseases 0.000 abstract 2
208000035475 disorder Diseases 0.000 abstract 2
230000004054 inflammatory process Effects 0.000 abstract 2
230000007803 itching Effects 0.000 abstract 2
206010002198 Anaphylactic reaction Diseases 0.000 abstract 1
206010006482 Bronchospasm Diseases 0.000 abstract 1
208000002177 Cataract Diseases 0.000 abstract 1
206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
206010009900 Colitis ulcerative Diseases 0.000 abstract 1
206010010744 Conjunctivitis allergic Diseases 0.000 abstract 1
206010012438 Dermatitis atopic Diseases 0.000 abstract 1
208000004262 Food Hypersensitivity Diseases 0.000 abstract 1
206010016946 Food allergy Diseases 0.000 abstract 1
102100029100 Hematopoietic prostaglandin D synthase Human genes 0.000 abstract 1
101000988802 Homo sapiens Hematopoietic prostaglandin D synthase Proteins 0.000 abstract 1
206010063837 Reperfusion injury Diseases 0.000 abstract 1
206010039085 Rhinitis allergic Diseases 0.000 abstract 1
208000006011 Stroke Diseases 0.000 abstract 1
201000008736 Systemic mastocytosis Diseases 0.000 abstract 1
201000006704 Ulcerative Colitis Diseases 0.000 abstract 1
208000002205 allergic conjunctivitis Diseases 0.000 abstract 1
208000026935 allergic disease Diseases 0.000 abstract 1
201000010105 allergic rhinitis Diseases 0.000 abstract 1
230000036783 anaphylactic response Effects 0.000 abstract 1
208000003455 anaphylaxis Diseases 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
208000024998 atopic conjunctivitis Diseases 0.000 abstract 1
201000008937 atopic dermatitis Diseases 0.000 abstract 1
208000010668 atopic eczema Diseases 0.000 abstract 1
206010006451 bronchitis Diseases 0.000 abstract 1
230000007885 bronchoconstriction Effects 0.000 abstract 1
230000020411 cell activation Effects 0.000 abstract 1
208000026106 cerebrovascular disease Diseases 0.000 abstract 1
230000001684 chronic effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
235000020932 food allergy Nutrition 0.000 abstract 1
210000003630 histaminocyte Anatomy 0.000 abstract 1
208000030603 inherited susceptibility to asthma Diseases 0.000 abstract 1
230000000302 ischemic effect Effects 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
208000008423 pleurisy Diseases 0.000 abstract 1
BHMBVRSPMRCCGG-OUTUXVNYSA-N prostaglandin D2 Chemical compound CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O BHMBVRSPMRCCGG-OUTUXVNYSA-N 0.000 abstract 1
BHMBVRSPMRCCGG-UHFFFAOYSA-N prostaglandine D2 Natural products CCCCCC(O)C=CC1C(CC=CCCCC(O)=O)C(O)CC1=O BHMBVRSPMRCCGG-UHFFFAOYSA-N 0.000 abstract 1
230000002207 retinal effect Effects 0.000 abstract 1
206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
238000007790 scraping Methods 0.000 abstract 1
230000035939 shock Effects 0.000 abstract 1
230000009885 systemic effect Effects 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Immunology (AREA)
Dermatology (AREA)
Ophthalmology & Optometry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Otolaryngology (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Indole Compounds (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

NO20090862A 2006-07-25 2009-02-24 2-fenyl-indoler som prostaglandin D2-reseptorantagonister NO20090862L (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US82029906P	2006-07-25	2006-07-25
US82030106P	2006-07-25	2006-07-25
US82030206P	2006-07-25	2006-07-25
PCT/US2007/073945 WO2008014186A1 (fr)	2006-07-25	2007-07-20	2-phényl-indoles en tant qu'antagonistes du récepteur de la prostaglandine d2

Publications (1)

Publication Number	Publication Date
NO20090862L true NO20090862L (no)	2009-02-24

Family

ID=38610820

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20090862A NO20090862L (no)	2006-07-25	2009-02-24	2-fenyl-indoler som prostaglandin D2-reseptorantagonister

Country Status (25)

Country	Link
US (1)	US20090176804A1 (fr)
EP (1)	EP2066628B1 (fr)
JP (1)	JP2009544721A (fr)
KR (1)	KR20090039735A (fr)
AR (1)	AR062051A1 (fr)
AT (1)	ATE485270T1 (fr)
AU (1)	AU2007276885A1 (fr)
BR (1)	BRPI0714554A2 (fr)
CA (1)	CA2659055A1 (fr)
CL (1)	CL2007002163A1 (fr)
CO (1)	CO6190511A2 (fr)
CR (1)	CR10577A (fr)
DE (1)	DE602007010010D1 (fr)
DK (1)	DK2066628T3 (fr)
EC (1)	ECSP099087A (fr)
GT (1)	GT200900016A (fr)
IL (1)	IL196587A0 (fr)
MA (1)	MA30643B1 (fr)
MX (1)	MX2009000830A (fr)
NO (1)	NO20090862L (fr)
PE (1)	PE20080549A1 (fr)
PT (1)	PT2066628E (fr)
TN (1)	TNSN08515A1 (fr)
TW (1)	TW200821286A (fr)
WO (1)	WO2008014186A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2009072576A1 (fr) *	2007-12-04	2009-06-11	Sapporo Breweries Limited	Stimulateur de la formation osseuse
BRPI0921038A2 (pt) *	2008-11-17	2019-09-24	Hoffmann La Roche	ácido naftilacéticos
AR080703A1 (es)	2010-03-22	2012-05-02	Actelion Pharmaceuticals Ltd	Derivados de 3-(heteroaril-amino)-1,2,3,4-tetrahidro-9h-carbazol, moduladores de receptores de prostaglandina d2, composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento de trastornos alergicos o inmunitarios tales como asma.
DK2697223T3 (en)	2011-04-14	2016-09-05	Actelion Pharmaceuticals Ltd	7- (heteroaryl-amino) -6,7,8,9-tetrahydro-pyrido [1,2-a] indole-acetic acid derivatives and their use as prostaglandin D2 receptor
ES2690782T3 (es)	2012-10-24	2018-11-22	Nyu Winthrop Hospital	Biomarcador no invasivo para identificar sujetos en riesgo de parto prematuro
JP2015089886A (ja) *	2013-11-06	2015-05-11	国立大学法人名古屋大学	嵩高い置換基を有する化合物を用いた植物成長調整剤
PE20161177A1 (es)	2014-03-17	2016-11-18	Actelion Pharmaceuticals Ltd	Derivados del acido acetico azaindol y su uso como moduladores del receptor de prostaglandina d2
WO2015140701A1 (fr)	2014-03-18	2015-09-24	Actelion Pharmaceuticals Ltd	Dérivés d'acide aza-indol-acétique et leur utilisation comme modulateurs des récepteurs de la prostaglandine d2
KR20180053345A (ko)	2015-09-15	2018-05-21	이도르시아 파마슈티컬스 리미티드	결정질 형태
CA3075688A1 (fr)	2017-09-13	2019-03-21	Progenity, Inc.	Biomarqueurs de pre-eclampsie ainsi que systemes et procedes associes
US12030879B2 (en)	2018-03-02	2024-07-09	Inflazome Limited	Sulfonyl acetamides as NLRP3 inhibitors
US11834433B2 (en)	2018-03-02	2023-12-05	Inflazome Limited	Compounds
EP3759078A1 (fr)	2018-03-02	2021-01-06	Inflazome Limited	Nouveaux composés
WO2019166632A1 (fr)	2018-03-02	2019-09-06	Inflazome Limited	Nouveaux composés
US12168653B2 (en)	2018-03-02	2024-12-17	Inflazome Limited	Sulfonamide derivates as NLRP3 inhibitors
NZ770757A (en) *	2018-05-09	2026-03-27	Glucox Biotech Ab	Novel sulfonamide derivatives having selective nox inhibiting activity
EP4070113A4 (fr)	2019-12-04	2023-12-20	Biora Therapeutics, Inc.	Évaluation de la prééclampsie à l'aide de dosages du facteur de croissance placentaire libre et dissocié
CN111333516B (zh) *	2020-04-14	2022-09-06	国药集团化学试剂有限公司	一种2-氯-5-溴硝基苯的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DOP2006000016A (es) *	2005-01-26	2006-07-31	Aventis Pharma Inc	2-fenil-indoles como antagonistas del receptor de la prostaglandina d2.

2007
- 2007-07-20 BR BRPI0714554-3A patent/BRPI0714554A2/pt not_active IP Right Cessation
- 2007-07-20 EP EP07799729A patent/EP2066628B1/fr active Active
- 2007-07-20 PT PT07799729T patent/PT2066628E/pt unknown
- 2007-07-20 DK DK07799729.4T patent/DK2066628T3/da active
- 2007-07-20 JP JP2009521914A patent/JP2009544721A/ja not_active Abandoned
- 2007-07-20 MX MX2009000830A patent/MX2009000830A/es active IP Right Grant
- 2007-07-20 WO PCT/US2007/073945 patent/WO2008014186A1/fr not_active Ceased
- 2007-07-20 AU AU2007276885A patent/AU2007276885A1/en not_active Abandoned
- 2007-07-20 KR KR1020097001687A patent/KR20090039735A/ko not_active Abandoned
- 2007-07-20 AT AT07799729T patent/ATE485270T1/de active
- 2007-07-20 CA CA002659055A patent/CA2659055A1/fr not_active Abandoned
- 2007-07-20 DE DE602007010010T patent/DE602007010010D1/de active Active
- 2007-07-23 PE PE2007000951A patent/PE20080549A1/es not_active Application Discontinuation
- 2007-07-24 AR ARP070103291A patent/AR062051A1/es not_active Application Discontinuation
- 2007-07-24 CL CL200702163A patent/CL2007002163A1/es unknown
- 2007-07-25 TW TW096127005A patent/TW200821286A/zh unknown
2008
- 2008-12-12 TN TNP2008000515A patent/TNSN08515A1/en unknown
2009
- 2009-01-15 CO CO09002745A patent/CO6190511A2/es not_active Application Discontinuation
- 2009-01-19 IL IL196587A patent/IL196587A0/en unknown
- 2009-01-21 CR CR10577A patent/CR10577A/es not_active Application Discontinuation
- 2009-01-22 US US12/357,725 patent/US20090176804A1/en not_active Abandoned
- 2009-01-23 GT GT200900016A patent/GT200900016A/es unknown
- 2009-01-23 EC EC2009009087A patent/ECSP099087A/es unknown
- 2009-02-13 MA MA31635A patent/MA30643B1/fr unknown
- 2009-02-24 NO NO20090862A patent/NO20090862L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
GT200900016A (es)	2010-10-13
DE602007010010D1 (de)	2010-12-02
AR062051A1 (es)	2008-08-10
US20090176804A1 (en)	2009-07-09
IL196587A0 (en)	2009-11-18
ATE485270T1 (de)	2010-11-15
CL2007002163A1 (es)	2008-02-08
CR10577A (es)	2009-03-20
JP2009544721A (ja)	2009-12-17
EP2066628B1 (fr)	2010-10-20
AU2007276885A1 (en)	2008-01-31
MA30643B1 (fr)	2009-08-03
KR20090039735A (ko)	2009-04-22
MX2009000830A (es)	2009-02-03
TW200821286A (en)	2008-05-16
ECSP099087A (es)	2009-02-27
CO6190511A2 (es)	2010-08-19
BRPI0714554A2 (pt)	2013-05-07
PE20080549A1 (es)	2008-06-20
EP2066628A1 (fr)	2009-06-10
WO2008014186A1 (fr)	2008-01-31
CA2659055A1 (fr)	2008-01-31
PT2066628E (pt)	2010-12-31
TNSN08515A1 (en)	2010-04-14
DK2066628T3 (da)	2011-02-07

Legal Events

Date	Code	Title	Description
2013-03-11	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20090862L (no)	2009-02-24	2-fenyl-indoler som prostaglandin D2-reseptorantagonister
NO20072440L (no)	2007-07-03	2,6-substituert-4-monosubstituertamino-pyrimidin som prostaglanding D2 reseptor antagonister
NO20084291L (no)	2008-11-11	2,6-substituert-4-monosubstituert aminopyridin som prostaglandin D2 reseptor-antagonister
NO20082072L (no)	2008-05-02	Dihydrogen fosfatsalt av en prostaglandin D2 reseptorantagonist
NO20074336L (no)	2007-10-23	2-fenylindoler som prostaglandin D2 reseptorantagonister
NO20024281L (no)	2002-11-08	Indolderivater, fremgangsmÕte for fremstilling av de samme og anvendelse derav
NO20070321L (no)	2007-03-12	Pyridazin-3(2H)-on-derivater og deres anvendelse som PDE4-inhibitorer
NO20070319L (no)	2007-03-06	Nye pyridazin-3(2H)-on-derivater og deres anvendelse som PDE4-inhibitorer
NO20090139L (no)	2009-03-05	Substituted phenyl acetic acids as DP-2 antagonists
BR0308518A (pt)	2005-02-22	Compostos ácidos carboxìlicos e drogas contendo os compostos como o ingrediente ativo
MX2009003100A (es)	2009-05-11	Inhibidores de fosfodiesterasa tipo iv.
WO2007114848A3 (fr)	2009-01-29	Composés chimiques
NO20084564L (no)	2008-12-02	Stramme "Constrained" forbindelser som CGRP-reseptor antagonister
NO20061207L (no)	2006-06-19	Karboksylsyreforbindelser og medisinske preparater inneholdende de samme som den aktive bestanddel
TW200635932A (en)	2006-10-16	New pyridothienopyrimidine derivatives
WO2008035316A3 (fr)	2008-11-27	Inhibiteurs de phosphodiestérase
WO2007046022A3 (fr)	2008-10-23	Inhibiteurs de phosphodiesterase de type-iv
UY30505A1 (es)	2008-02-29	Fenilindoles como antagonistas del receptor de la prostaglandina d2