NO20091345L - Rettet anvendelse - Google Patents
Rettet anvendelseInfo
- Publication number
- NO20091345L NO20091345L NO20091345A NO20091345A NO20091345L NO 20091345 L NO20091345 L NO 20091345L NO 20091345 A NO20091345 A NO 20091345A NO 20091345 A NO20091345 A NO 20091345A NO 20091345 L NO20091345 L NO 20091345L
- Authority
- NO
- Norway
- Prior art keywords
- subject
- liquid
- active substance
- localized area
- mouth
- Prior art date
Links
- 239000007788 liquid Substances 0.000 abstract 5
- 239000013543 active substance Substances 0.000 abstract 4
- 210000000214 mouth Anatomy 0.000 abstract 4
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000005179 oral vestibule Anatomy 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Oppfinnelsen er rettet mot en fremgangsmåte for oral administrering av en væske inneholdende en aktiv substans til et subjekt for forbedret absorpsjon inn i subjektets blodstrøm, som innbefatter trinnene med å tilveiebringe en tilførselsanordning inneholdende væsken og med et munnstykke for å lede en væske i en definert retning under tilførselen; rette munnstykket mot et lokalisert område til subjektets munn som er spesielt egnet for økt opptak og raskere virkningsstart av den aktive substansen i forhold til andre områder til og/eller hele munnen; og utlevere en målt mengde av væsken direkte til det lokaliserte området ved bruk av tilførselsanordningen, og en sprøyteanordning for administrering av en aktiv substans til munnhulrommet til et subjekt som innbefatter en beholder som er i stand til å inneholde en væske inneholdende en aktiv substans, og et munnstykke som er konstruert for å utlevere væsken inneholdende substansen i en definert retning og direkte til et lokalisert område av subjektets munn, hvilke lokalisert område er oral vestibylen.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200601246 | 2006-09-27 | ||
| US95161907P | 2007-07-24 | 2007-07-24 | |
| PCT/EP2007/008420 WO2008037470A1 (en) | 2006-09-27 | 2007-09-27 | Directional use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20091345L true NO20091345L (no) | 2009-04-01 |
Family
ID=38776389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20091345A NO20091345L (no) | 2006-09-27 | 2009-04-01 | Rettet anvendelse |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10092715B2 (no) |
| EP (1) | EP2068982A1 (no) |
| JP (2) | JP2010504931A (no) |
| KR (1) | KR20090055606A (no) |
| CN (1) | CN101516426A (no) |
| AU (1) | AU2007302256A1 (no) |
| BR (1) | BRPI0716995A2 (no) |
| CA (1) | CA2660362C (no) |
| IL (1) | IL197573A0 (no) |
| MX (1) | MX2009001865A (no) |
| NO (1) | NO20091345L (no) |
| RU (1) | RU2009115720A (no) |
| WO (1) | WO2008037470A1 (no) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT507187B1 (de) * | 2008-10-23 | 2010-03-15 | Helmut Dr Buchberger | Inhalator |
| CA2750815C (en) * | 2009-02-09 | 2018-03-13 | Swetree Technologies Ab | Polymer shells |
| US20110268809A1 (en) | 2010-04-28 | 2011-11-03 | Paul Andrew Brinkley | Nicotine-Containing Pharmaceutical Compositions |
| US20110274628A1 (en) | 2010-05-07 | 2011-11-10 | Borschke August J | Nicotine-containing pharmaceutical compositions |
| CA2824970C (en) | 2011-02-11 | 2016-05-03 | Batmark Limited | Inhaler component |
| AT510837B1 (de) | 2011-07-27 | 2012-07-15 | Helmut Dr Buchberger | Inhalatorkomponente |
| PL2753202T3 (pl) | 2011-09-06 | 2016-11-30 | Podgrzewanie materiału przeznaczonego do palenia | |
| EP3892125A3 (en) | 2011-09-06 | 2022-01-05 | Nicoventures Trading Limited | Heating smokable material |
| US20130078307A1 (en) | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
| AT511344B1 (de) | 2011-10-21 | 2012-11-15 | Helmut Dr Buchberger | Inhalatorkomponente |
| US9907748B2 (en) | 2011-10-21 | 2018-03-06 | Niconovum Usa, Inc. | Excipients for nicotine-containing therapeutic compositions |
| GB201207039D0 (en) | 2012-04-23 | 2012-06-06 | British American Tobacco Co | Heating smokeable material |
| GB2504075A (en) | 2012-07-16 | 2014-01-22 | Nicoventures Holdings Ltd | Electronic smoking device |
| GB2504076A (en) | 2012-07-16 | 2014-01-22 | Nicoventures Holdings Ltd | Electronic smoking device |
| USD701599S1 (en) * | 2013-03-26 | 2014-03-25 | Pediatric Innovations USA, LLC | Nasal device |
| USD732658S1 (en) | 2013-03-26 | 2015-06-23 | Pediatric Innovations USA, LLC | Nasal device with airplane wings |
| USD732659S1 (en) | 2013-03-26 | 2015-06-23 | Pediatric Innovations USA, LLC | Car-shaped nasal device |
| USD701956S1 (en) * | 2013-03-26 | 2014-04-01 | Pediatric Innovations USA, LLC | Nasal device |
| GB2513639A (en) | 2013-05-02 | 2014-11-05 | Nicoventures Holdings Ltd | Electronic cigarette |
| GB2513637A (en) | 2013-05-02 | 2014-11-05 | Nicoventures Holdings Ltd | Electronic cigarette |
| GB2514893B (en) | 2013-06-04 | 2017-12-06 | Nicoventures Holdings Ltd | Container |
| GB201407426D0 (en) | 2014-04-28 | 2014-06-11 | Batmark Ltd | Aerosol forming component |
| GB2528673B (en) | 2014-07-25 | 2020-07-01 | Nicoventures Holdings Ltd | Aerosol provision system |
| GB2533135B (en) | 2014-12-11 | 2020-11-11 | Nicoventures Holdings Ltd | Aerosol provision systems |
| GB201505595D0 (en) | 2015-03-31 | 2015-05-13 | British American Tobacco Co | Cartridge for use with apparatus for heating smokeable material |
| GB201505597D0 (en) | 2015-03-31 | 2015-05-13 | British American Tobacco Co | Article for use with apparatus for heating smokable material |
| GB201511361D0 (en) | 2015-06-29 | 2015-08-12 | Nicoventures Holdings Ltd | Electronic vapour provision system |
| GB201511349D0 (en) | 2015-06-29 | 2015-08-12 | Nicoventures Holdings Ltd | Electronic aerosol provision systems |
| US20170055584A1 (en) | 2015-08-31 | 2017-03-02 | British American Tobacco (Investments) Limited | Article for use with apparatus for heating smokable material |
| US11924930B2 (en) | 2015-08-31 | 2024-03-05 | Nicoventures Trading Limited | Article for use with apparatus for heating smokable material |
| GB201516729D0 (en) * | 2015-09-22 | 2015-11-04 | The Technology Partnership Plc | Liquid nicotine formulation |
| GB2542838B (en) | 2015-10-01 | 2022-01-12 | Nicoventures Trading Ltd | Aerosol provision system |
| US20170119046A1 (en) | 2015-10-30 | 2017-05-04 | British American Tobacco (Investments) Limited | Apparatus for Heating Smokable Material |
| US10532046B2 (en) | 2015-12-03 | 2020-01-14 | Niconovum Usa, Inc. | Multi-phase delivery compositions and products incorporating such compositions |
| US20170165252A1 (en) | 2015-12-10 | 2017-06-15 | Niconovum Usa Inc. | Protein-enriched therapeutic composition |
| US11744964B2 (en) | 2016-04-27 | 2023-09-05 | Nicoventures Trading Limited | Electronic aerosol provision system and vaporizer therefor |
| WO2018113916A1 (en) * | 2016-12-20 | 2018-06-28 | Fertin Pharma A/S | A mucoadhesive oromucosal formulation comprising a nicotine complex |
| CA3085065C (en) | 2017-12-08 | 2023-12-05 | Fertin Pharma A/S | Formulations providing high nicotine concentrations |
| CA3085064C (en) * | 2017-12-08 | 2023-10-24 | Fertin Pharma A/S | Nicotine mouth spray |
| WO2019110072A1 (en) | 2017-12-08 | 2019-06-13 | Fertin Pharma A/S | Nicotine tablet |
| CN112384504A (zh) | 2018-06-15 | 2021-02-19 | R.J.雷诺兹烟草公司 | 烟碱的纯化 |
| JP6676805B2 (ja) * | 2018-07-12 | 2020-04-08 | 株式会社 東亜産業 | 芳香カートリッジ用充填物、それを有する芳香カートリッジ用エアロゾル形成基材およびそれを有する芳香カートリッジ |
| JP7528084B2 (ja) * | 2018-12-28 | 2024-08-05 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 金属塩を含むニコチン製剤 |
| WO2020235112A1 (ja) | 2019-05-21 | 2020-11-26 | 株式会社 東亜産業 | 被加熱芳香発生体及び芳香カートリッジ、並びに、被加熱芳香発生体の製造方法及び製造装置 |
| US12213510B2 (en) | 2019-09-11 | 2025-02-04 | Nicoventures Trading Limited | Pouched products with enhanced flavor stability |
| US12342847B2 (en) | 2019-09-11 | 2025-07-01 | Nicoventures Trading Limited | Oral product with cellulosic flavor stabilizer |
| CN110558605B (zh) * | 2019-09-27 | 2021-07-06 | 深圳雾芯科技有限公司 | 电子烟液 |
| US12433321B2 (en) | 2019-12-09 | 2025-10-07 | Nicoventures Trading Limited | Oral composition with beet material |
| US12439952B2 (en) | 2019-12-09 | 2025-10-14 | Nicoventures Trading Limited | Moist oral compositions |
| US12599160B2 (en) | 2019-12-09 | 2026-04-14 | Nicoventures Trading Limited | Lipid-containing oral composition |
| US12137723B2 (en) | 2019-12-09 | 2024-11-12 | Nicoventures Trading Limited | Oral products with active ingredient combinations |
| US12310959B2 (en) | 2019-12-09 | 2025-05-27 | Nicoventures Trading Limited | Oral compositions with reduced water content |
| US12439949B2 (en) | 2019-12-09 | 2025-10-14 | Nicoventures Trading Limited | Oral compositions with reduced water activity |
| US12520867B2 (en) | 2019-12-09 | 2026-01-13 | Nicoventures Trading Limited | Buffered oral compositions |
| US12171872B2 (en) | 2019-12-09 | 2024-12-24 | Nicoventures Trading Limited | Oral compositions and methods of manufacture |
| US11672862B2 (en) | 2019-12-09 | 2023-06-13 | Nicoventures Trading Limited | Oral products with reduced irritation |
| EP4072338A1 (en) | 2019-12-09 | 2022-10-19 | Nicoventures Trading Limited | Agents for oral composition |
| US11793230B2 (en) | 2019-12-09 | 2023-10-24 | Nicoventures Trading Limited | Oral products with improved binding of active ingredients |
| US11826462B2 (en) | 2019-12-09 | 2023-11-28 | Nicoventures Trading Limited | Oral product with sustained flavor release |
| US12151023B2 (en) | 2019-12-09 | 2024-11-26 | Nicoventures Trading Limited | Oral composition with beet material |
| US12550928B2 (en) | 2019-12-09 | 2026-02-17 | Nicoventures Trading Limited | Liquid oral composition |
| US11617744B2 (en) | 2019-12-09 | 2023-04-04 | Nico Ventures Trading Limited | Moist oral compositions |
| US12491250B2 (en) | 2019-12-09 | 2025-12-09 | Nicoventures Trading Limited | Oral composition with nanocrystalline cellulose |
| US11889856B2 (en) | 2019-12-09 | 2024-02-06 | Nicoventures Trading Limited | Oral foam composition |
| US11872231B2 (en) | 2019-12-09 | 2024-01-16 | Nicoventures Trading Limited | Moist oral product comprising an active ingredient |
| US11883527B2 (en) | 2019-12-09 | 2024-01-30 | Nicoventures Trading Limited | Oral composition and method of manufacture |
| US11969502B2 (en) | 2019-12-09 | 2024-04-30 | Nicoventures Trading Limited | Oral products |
| JP2023504756A (ja) | 2019-12-09 | 2023-02-06 | ニコベンチャーズ トレーディング リミテッド | カンナビノイドを含む口腔用製品 |
| CA3181912A1 (en) | 2020-06-08 | 2021-12-16 | Anthony Richard Gerardi | Effervescent oral composition comprising an active ingredient |
| US11839602B2 (en) | 2020-11-25 | 2023-12-12 | Nicoventures Trading Limited | Oral cannabinoid product with lipid component |
| WO2022261552A1 (en) * | 2021-06-11 | 2022-12-15 | Boa Nutrition, Inc. | Nozzle with fan for delivering aerosols |
| MX2023015529A (es) | 2021-06-25 | 2024-03-05 | Nicoventures Trading Ltd | Productos orales y metodo de fabricacion. |
| JP2024530905A (ja) | 2021-07-30 | 2024-08-27 | ニコベンチャーズ トレーディング リミテッド | 微結晶性セルロースを含むエアロゾル生成基材 |
| CA3233375A1 (en) | 2021-09-30 | 2023-04-06 | Michael Zawadzki | Oral product with a basic amine and an ion pairing agent |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2619718B1 (fr) * | 1987-09-02 | 1991-07-12 | Medibrevex | Nouvelles formes galeniques de beta-2-mimetiques pour administration par voie per- et sublinguale |
| GB8828468D0 (en) | 1988-12-06 | 1989-01-05 | Stoppers Co Ltd | Nicotine containing lozenge |
| US5326570A (en) * | 1991-07-23 | 1994-07-05 | Pharmavene, Inc. | Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine |
| US5362496A (en) | 1993-08-04 | 1994-11-08 | Pharmetrix Corporation | Method and therapeutic system for smoking cessation |
| IT233948Y1 (it) | 1994-07-20 | 2000-02-16 | Plastiape Spa | Dispositivo erogatore tascabile,particolrmente studiato per immettere nel cavo orale sostanze medicamentose nebulizzate |
| US5955098A (en) * | 1996-04-12 | 1999-09-21 | Flemington Pharmaceutical Corp. | Buccal non polar spray or capsule |
| FI974578L (fi) * | 1997-12-19 | 1999-06-20 | Orion Yhtymae Oyj | Menetelmä levosimendaanin antamiseksi |
| US5981499A (en) | 1998-02-20 | 1999-11-09 | Atlantic Biomed Corporation | Lesion-directed antibiotics in dry dosage forms for the treatment of shallow ulcers of the oral mucosa |
| US6080783A (en) * | 1998-09-01 | 2000-06-27 | Gum Tech International, Inc. | Method and composition for delivering zinc to the nasal membrane |
| CN1354624A (zh) | 1998-12-15 | 2002-06-19 | Wm·雷格利Jr·公司 | 从口香糖中控制释放活性剂 |
| US6799576B2 (en) * | 1999-07-16 | 2004-10-05 | Aradigm Corporation | System for effecting smoking cessation |
| NZ521034A (en) * | 2000-02-28 | 2004-08-27 | Vectura Ltd | Improvements in or relating to the delivery of oral drugs |
| SE0003665D0 (sv) * | 2000-10-11 | 2000-10-11 | Astrazeneca Ab | A delivery device |
| DK1361864T3 (en) * | 2001-02-14 | 2014-03-03 | Gw Pharma Ltd | FLYLDENDE SPRAY FORMULATIONS FOR buccal administration of cannabinoids |
| SE521512C2 (sv) * | 2001-06-25 | 2003-11-11 | Niconovum Ab | Anordning för administrering av en substans till främre delen av en individs munhåla |
| US20040037879A1 (en) | 2001-11-02 | 2004-02-26 | Adusumilli Prasad S. | Oral controlled release forms useful for reducing or preventing nicotine cravings |
| SE0104388D0 (sv) | 2001-12-27 | 2001-12-27 | Pharmacia Ab | New formulation and use and manufacture thereof |
| PT1578422E (pt) * | 2002-12-20 | 2007-06-14 | Niconovum Ab | Material particulado contendo nicotina fisicamente e quimicamente estável |
| EP1617823B1 (en) * | 2003-01-24 | 2019-01-09 | Nicachet AB | A pouch comprising a nicotine composition for transmucosal delivery |
| GB0305581D0 (en) | 2003-03-11 | 2003-04-16 | Dallas Burston Ltd | Dispensing devices |
| US20050150489A1 (en) * | 2004-01-12 | 2005-07-14 | Steve Dunfield | Dispensing medicaments based on rates of medicament action |
| JP2007533697A (ja) * | 2004-04-22 | 2007-11-22 | デュオコート エービー | グルココルチコイド救急治療用の医薬組成物 |
| EP1893953A2 (en) * | 2005-05-18 | 2008-03-05 | The GI Company, Inc | Oral drug delivery system and methods of use thereof |
-
2007
- 2007-09-27 CN CNA2007800361099A patent/CN101516426A/zh active Pending
- 2007-09-27 JP JP2009529608A patent/JP2010504931A/ja active Pending
- 2007-09-27 US US12/440,817 patent/US10092715B2/en active Active
- 2007-09-27 AU AU2007302256A patent/AU2007302256A1/en not_active Abandoned
- 2007-09-27 MX MX2009001865A patent/MX2009001865A/es not_active Application Discontinuation
- 2007-09-27 EP EP07818503A patent/EP2068982A1/en not_active Withdrawn
- 2007-09-27 CA CA2660362A patent/CA2660362C/en active Active
- 2007-09-27 RU RU2009115720/14A patent/RU2009115720A/ru unknown
- 2007-09-27 KR KR1020097006341A patent/KR20090055606A/ko not_active Ceased
- 2007-09-27 WO PCT/EP2007/008420 patent/WO2008037470A1/en not_active Ceased
- 2007-09-27 BR BRPI0716995-7A patent/BRPI0716995A2/pt not_active Application Discontinuation
-
2009
- 2009-03-12 IL IL197573A patent/IL197573A0/en unknown
- 2009-04-01 NO NO20091345A patent/NO20091345L/no not_active Application Discontinuation
-
2013
- 2013-11-08 JP JP2013232105A patent/JP2014076370A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN101516426A (zh) | 2009-08-26 |
| JP2010504931A (ja) | 2010-02-18 |
| MX2009001865A (es) | 2009-04-07 |
| KR20090055606A (ko) | 2009-06-02 |
| AU2007302256A1 (en) | 2008-04-03 |
| CA2660362A1 (en) | 2008-04-03 |
| WO2008037470A1 (en) | 2008-04-03 |
| US10092715B2 (en) | 2018-10-09 |
| RU2009115720A (ru) | 2010-11-10 |
| EP2068982A1 (en) | 2009-06-17 |
| US20100108059A1 (en) | 2010-05-06 |
| IL197573A0 (en) | 2009-12-24 |
| BRPI0716995A2 (pt) | 2013-10-15 |
| JP2014076370A (ja) | 2014-05-01 |
| CA2660362C (en) | 2018-03-20 |
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