NO20092902L - 6-benzyl-2,3,4,7-tetrahydro-indolo[2,3-c]kinolinforbindelser nyttige som PDE5-inhibitorer - Google Patents

6-benzyl-2,3,4,7-tetrahydro-indolo[2,3-c]kinolinforbindelser nyttige som PDE5-inhibitorer

Info

Publication number
NO20092902L
NO20092902L NO20092902A NO20092902A NO20092902L NO 20092902 L NO20092902 L NO 20092902L NO 20092902 A NO20092902 A NO 20092902A NO 20092902 A NO20092902 A NO 20092902A NO 20092902 L NO20092902 L NO 20092902L
Authority
NO
Norway
Prior art keywords
tetrahydroindolo
benzyl
compounds useful
pde5 inhibitors
quinoline compounds
Prior art date
Application number
NO20092902A
Other languages
English (en)
Norwegian (no)
Inventor
Dieter Flockerzi
Beate Schmidt
Degenhard Marx
Ulrich Kautz
Steffen Weinbrenner
Daniela Hauser
Torsten Dunkern
Thomas Stengel
Jorg Diefenbach
Johannes A M Christiaans
Wiro M P B Menge
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of NO20092902L publication Critical patent/NO20092902L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20092902A 2007-02-05 2009-08-27 6-benzyl-2,3,4,7-tetrahydro-indolo[2,3-c]kinolinforbindelser nyttige som PDE5-inhibitorer NO20092902L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07101742A EP1953159A1 (fr) 2007-02-05 2007-02-05 Composés de 6-benzyl-2,3,4,7-tétrahydro-indolo[2,3-c]quinoline en tant qu'inhibiteurs de la PDE5
PCT/EP2008/051076 WO2008095835A1 (fr) 2007-02-05 2008-01-30 Composés de 6-benzyl-2, 3,4, 7-tétrahydro-indolo [2, 3-c] quinoline utiles en tant qu'inhibiteurs de pde5

Publications (1)

Publication Number Publication Date
NO20092902L true NO20092902L (no) 2009-08-27

Family

ID=38222238

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092902A NO20092902L (no) 2007-02-05 2009-08-27 6-benzyl-2,3,4,7-tetrahydro-indolo[2,3-c]kinolinforbindelser nyttige som PDE5-inhibitorer

Country Status (18)

Country Link
US (1) US20100120730A1 (fr)
EP (2) EP1953159A1 (fr)
JP (1) JP2010517958A (fr)
KR (1) KR20090106633A (fr)
CN (1) CN101605791A (fr)
AR (1) AR065157A1 (fr)
AU (1) AU2008212987A1 (fr)
BR (1) BRPI0808378A2 (fr)
CA (1) CA2675357A1 (fr)
EA (1) EA200901034A1 (fr)
IL (1) IL200102A0 (fr)
MA (1) MA31229B1 (fr)
MX (1) MX2009007682A (fr)
NO (1) NO20092902L (fr)
TN (1) TN2009000267A1 (fr)
TW (1) TW200902528A (fr)
WO (1) WO2008095835A1 (fr)
ZA (1) ZA200904440B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820691B2 (en) * 2006-08-28 2010-10-26 Medipropharma, Inc. Indoloquinoline compounds as calcium channel blockers
US20090131442A1 (en) * 2007-11-16 2009-05-21 Joseph Bernstein Method of Treating Bone Pain Caused by Osteoarthritis
WO2010015587A1 (fr) * 2008-08-05 2010-02-11 Nycomed Gmbh Composés 5-benzyl-1,2,3,6-tétrahydro-4,6-diaza-cyclopenta[c]fluorène et composés 5-benzyl-1,2,3,6-tétrahydro-4,6-diaza-cyclohepta[c]fluorène
WO2010015585A1 (fr) * 2008-08-05 2010-02-11 Nycomed Gmbh Composés de 6-benzyl-2,3,4,7-tétrahydro-indolo[2,3-c]quinoléine
WO2010015586A2 (fr) * 2008-08-05 2010-02-11 Nycomed Gmbh Composés 2,3,4,7-tétrahydro-indolo[2,3-c]quinoléine
WO2010015588A1 (fr) * 2008-08-05 2010-02-11 Nycomed Gmbh Composés hétérocycliques tétracycliques à substitution benzyle
WO2010015589A1 (fr) * 2008-08-05 2010-02-11 Nycomed Gmbh Composés hétérocycliques tétracycliques à substitution benzyle comme inhibiteurs de pde5
WO2011015523A1 (fr) 2009-08-03 2011-02-10 Nycomed Gmbh Composés hétérocycliques tétracycliques substitués par benzyle
WO2013109738A1 (fr) 2012-01-17 2013-07-25 The Trustees Of Columbia University In The City Of New York Nouveaux inhibiteurs de la phosphodiestérase et utilisations de ceux-ci
WO2015009930A2 (fr) 2013-07-17 2015-01-22 The Trustees Of Columbia University In The City Of New York Nouveaux inhibiteurs de la phosphodiestérase et utilisations de ceux-ci
EP4665351A1 (fr) 2023-02-16 2025-12-24 University of Rochester Amélioration de l'efflux glymphatique-lymphatique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4220779B2 (ja) * 2001-02-12 2009-02-04 リリー アイコス リミテッド ライアビリティ カンパニー 化学化合物

Also Published As

Publication number Publication date
TN2009000267A1 (en) 2010-10-18
TW200902528A (en) 2009-01-16
EP1953159A1 (fr) 2008-08-06
JP2010517958A (ja) 2010-05-27
CA2675357A1 (fr) 2008-08-14
US20100120730A1 (en) 2010-05-13
IL200102A0 (en) 2010-04-15
ZA200904440B (en) 2010-04-28
CN101605791A (zh) 2009-12-16
EP2109610A1 (fr) 2009-10-21
WO2008095835A1 (fr) 2008-08-14
BRPI0808378A2 (pt) 2014-07-01
EA200901034A1 (ru) 2010-02-26
AU2008212987A1 (en) 2008-08-14
AR065157A1 (es) 2009-05-20
MX2009007682A (es) 2009-07-29
MA31229B1 (fr) 2010-03-01
KR20090106633A (ko) 2009-10-09

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