NO301236B1 - Analogifremgangsmåte for fremstilling av terapeutisk aktive polypeptider - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive polypeptider Download PDF

Info

Publication number
NO301236B1
NO301236B1 NO892733A NO892733A NO301236B1 NO 301236 B1 NO301236 B1 NO 301236B1 NO 892733 A NO892733 A NO 892733A NO 892733 A NO892733 A NO 892733A NO 301236 B1 NO301236 B1 NO 301236B1
Authority
NO
Norway
Prior art keywords
leu
lys
glu
amino
suc
Prior art date
Application number
NO892733A
Other languages
English (en)
Norwegian (no)
Other versions
NO892733D0 (no
NO892733L (no
Inventor
Larry Raymond Mclean
John Leonard Krstenansky
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO892733D0 publication Critical patent/NO892733D0/no
Publication of NO892733L publication Critical patent/NO892733L/no
Publication of NO301236B1 publication Critical patent/NO301236B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785Alveolar surfactant peptides; Pulmonary surfactant peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO892733A 1988-07-01 1989-06-30 Analogifremgangsmåte for fremstilling av terapeutisk aktive polypeptider NO301236B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21422888A 1988-07-01 1988-07-01
US28279588A 1988-12-09 1988-12-09

Publications (3)

Publication Number Publication Date
NO892733D0 NO892733D0 (no) 1989-06-30
NO892733L NO892733L (no) 1990-01-02
NO301236B1 true NO301236B1 (no) 1997-09-29

Family

ID=26908797

Family Applications (1)

Application Number Title Priority Date Filing Date
NO892733A NO301236B1 (no) 1988-07-01 1989-06-30 Analogifremgangsmåte for fremstilling av terapeutisk aktive polypeptider

Country Status (13)

Country Link
EP (1) EP0348967A3 (fr)
JP (1) JPH0253798A (fr)
KR (1) KR900001719A (fr)
CN (1) CN1037350C (fr)
AR (1) AR245141A1 (fr)
AU (1) AU617827B2 (fr)
DK (1) DK326889A (fr)
FI (1) FI95914C (fr)
HU (1) HU204288B (fr)
IL (1) IL90790A (fr)
NO (1) NO301236B1 (fr)
NZ (1) NZ229737A (fr)
PT (1) PT91027B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260273A (en) * 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
DE69125750D1 (de) * 1990-05-21 1997-05-28 Abbott Lab Fettsäure-Oberflächenaktives-Lungenprotein Konjate
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
AU671850B2 (en) * 1992-07-29 1996-09-12 Merrell Dow Pharmaceuticals Inc. Peptide lung surfactants and therapeutic combinations
AU664112B2 (en) * 1992-07-31 1995-11-02 Merrell Dow Pharmaceuticals Inc. Synthetic peptide lung surfactants having covalently bonded antioxidants
RU2144925C1 (ru) * 1993-12-08 2000-01-27 ТТ Фармасьютикалс, Инк. Новые синтетические пептиды, легочная поверхностно-активная композиция, лекарственный препарат для лечения респираторного дистресс-синдрома
GB9524007D0 (en) * 1995-11-23 1996-01-24 Bangham Alec D Endotrachael tubes with pulmonary medicaments
US7053176B1 (en) 1999-09-16 2006-05-30 Altana Pharma Ag Combination of C1-INH and lung surfactant for the treatment of respiratory disorders
CN1558927A (zh) 2001-09-25 2004-12-29 ����ɭ���ڻ�ѧר����˾ 增塑聚氯乙烯
AU2002338882B2 (en) 2001-10-11 2008-04-03 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Novel use of pulmonary surfactant
CA2575513C (fr) 2004-08-06 2014-09-16 Altana Pharma Ag Composition comprenant un tensioactif pulmonaire et un peptide derive de tnf
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
WO2010068754A2 (fr) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Procédés et compositions pour la délivrance de médicaments aux poumons
CN111568853B (zh) * 2020-04-30 2023-07-28 杭州濡湜生物科技有限公司 一种新型肺部智能释药系统

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4705684A (en) * 1985-05-31 1987-11-10 The University Of Tennessee Research Corporation Synthetic M proteins - streptococci type 6

Also Published As

Publication number Publication date
NZ229737A (en) 1991-05-28
EP0348967A3 (fr) 1990-09-12
EP0348967A2 (fr) 1990-01-03
CN1037350C (zh) 1998-02-11
DK326889A (da) 1990-01-02
HU204288B (en) 1991-12-30
PT91027B (pt) 1995-03-31
JPH0253798A (ja) 1990-02-22
NO892733D0 (no) 1989-06-30
AU617827B2 (en) 1991-12-05
NO892733L (no) 1990-01-02
HUT50848A (en) 1990-03-28
FI893214A0 (fi) 1989-06-30
IL90790A0 (en) 1990-01-18
IL90790A (en) 1996-10-31
FI95914B (fi) 1995-12-29
FI893214A7 (fi) 1990-01-02
FI95914C (fi) 1996-04-10
AR245141A1 (es) 1993-12-30
KR900001719A (ko) 1990-02-27
AU3722789A (en) 1990-01-04
CN1039029A (zh) 1990-01-24
DK326889D0 (da) 1989-06-30
PT91027A (pt) 1990-02-08

Similar Documents

Publication Publication Date Title
US4861756A (en) Synthetic pulmonary surfactant
EP0383837B1 (fr) Proteines a effet tensio-actif alveolaire
NO301236B1 (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive polypeptider
US5683982A (en) Synthetic lung surfactant having antioxidant properties
NO342038B1 (no) Rekonstituerte surfaktanter med forbedrede egenskaper
US5104853A (en) Alveolar surfactant proteins having cys to ser mutations
JPWO1995015980A1 (ja) 新規な合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤
EP0652894B1 (fr) Tensioactifs pulmonaires synthetiques a peptides, possedant des antioxydants lies de maniere covalente
EP0656902B1 (fr) Tensioactifs pulmonaires a peptides et combinaisons therapeutiques
US5169761A (en) Dna encoding and expression systems for alveolar surfactant proteins
JP7499533B2 (ja) 新規アドレノメデュリン類縁体、その製造方法及びその医薬用途
CA2137349C (fr) Surfactants peptidiques a action pulmonaire et combinaisons therapeutiques
HK1008744A1 (en) Alveolar surfactant proteins
HK1008744B (en) Alveolar surfactant proteins