NO302184B1 - Fremgangsmåte for kjemisk modifisering av proteiner og peptider, samt proteiner og peptider fremstilt ved fremgangsmåten - Google Patents

Fremgangsmåte for kjemisk modifisering av proteiner og peptider, samt proteiner og peptider fremstilt ved fremgangsmåten Download PDF

Info

Publication number: NO302184B1
Authority: NO; Norway
Prior art keywords: protein; peptide; stated; acid; group
Prior art date: 1987-06-30

Application number

NO882836A

Other languages

English (en)

Norwegian (no)

Other versions

NO882836D0 (no

NO882836L (no

Inventor

Guy Levesque

Jerome Souppe

Jean-Louis Seris

Valerie Bellenger

Original Assignee

Elf Aquitaine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-30

Filing date

1988-06-27

Publication date

1998-02-02

1987-06-30 Priority claimed from FR8709198A external-priority patent/FR2617487B1/fr

1988-05-25 Priority claimed from FR8806914A external-priority patent/FR2631971B1/fr

1988-06-27 Application filed by Elf Aquitaine filed Critical Elf Aquitaine

1988-06-27 Publication of NO882836D0 publication Critical patent/NO882836D0/no

1989-01-02 Publication of NO882836L publication Critical patent/NO882836L/no

1998-02-02 Publication of NO302184B1 publication Critical patent/NO302184B1/no

Links

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XJDQUPFWVIUWNZ-UHFFFAOYSA-N o-ethyl propanethioate Chemical group CCOC(=S)CC XJDQUPFWVIUWNZ-UHFFFAOYSA-N 0.000 description 1
108010069653 peptide E (adrenal medulla) Proteins 0.000 description 1
238000010647 peptide synthesis reaction Methods 0.000 description 1
230000000704 physical effect Effects 0.000 description 1
229920001515 polyalkylene glycol Polymers 0.000 description 1
238000006116 polymerization reaction Methods 0.000 description 1
150000003141 primary amines Chemical class 0.000 description 1
239000012460 protein solution Substances 0.000 description 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
150000003242 quaternary ammonium salts Chemical class 0.000 description 1
230000009257 reactivity Effects 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
150000003335 secondary amines Chemical class 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
230000007928 solubilization Effects 0.000 description 1
238000005063 solubilization Methods 0.000 description 1
230000003381 solubilizing effect Effects 0.000 description 1
238000001228 spectrum Methods 0.000 description 1
229910052717 sulfur Inorganic materials 0.000 description 1
239000011593 sulfur Substances 0.000 description 1
239000000725 suspension Substances 0.000 description 1
150000003512 tertiary amines Chemical class 0.000 description 1
125000005207 tetraalkylammonium group Chemical group 0.000 description 1
QEMXHQIAXOOASZ-UHFFFAOYSA-N tetramethylammonium Chemical compound C[N+](C)(C)C QEMXHQIAXOOASZ-UHFFFAOYSA-N 0.000 description 1
150000007970 thio esters Chemical group 0.000 description 1
125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 description 1
125000003944 tolyl group Chemical group 0.000 description 1
JJPVWQWOOQYHCB-UHFFFAOYSA-N triethyl(phenyl)azanium Chemical compound CC[N+](CC)(CC)C1=CC=CC=C1 JJPVWQWOOQYHCB-UHFFFAOYSA-N 0.000 description 1
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
WJUFSDZVCOTFON-UHFFFAOYSA-N veratraldehyde Chemical compound COC1=CC=C(C=O)C=C1OC WJUFSDZVCOTFON-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/63—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Analytical Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Botany (AREA)
Enzymes And Modification Thereof (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

NO882836A 1987-06-30 1988-06-27 Fremgangsmåte for kjemisk modifisering av proteiner og peptider, samt proteiner og peptider fremstilt ved fremgangsmåten NO302184B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8709198A FR2617487B1 (fr)	1987-06-30	1987-06-30	Procede de modification chimique de protides et produits ainsi modifies
FR8806914A FR2631971B1 (fr)	1988-05-25	1988-05-25	Greffage de dithioacides sur des protides

Publications (3)

Publication Number	Publication Date
NO882836D0 NO882836D0 (no)	1988-06-27
NO882836L NO882836L (no)	1989-01-02
NO302184B1 true NO302184B1 (no)	1998-02-02

Family

ID=26226066

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO882836A NO302184B1 (no)	1987-06-30	1988-06-27	Fremgangsmåte for kjemisk modifisering av proteiner og peptider, samt proteiner og peptider fremstilt ved fremgangsmåten

Country Status (10)

Country	Link
US (1)	US4870016A (da)
EP (1)	EP0300849B1 (da)
JP (1)	JP2722205B2 (da)
CA (1)	CA1331571C (da)
DE (1)	DE3881774T2 (da)
DK (1)	DK359788A (da)
ES (1)	ES2056946T3 (da)
GR (1)	GR890300105T1 (da)
NO (1)	NO302184B1 (da)
PT (1)	PT87858B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2637292B1 (fr) *	1988-10-03	1992-06-05	Agronomique Inst Nat Rech	Procede de production de lignine-peroxydase par des cellules non-proliferantes de phanerochaete chrysosporium
US5719039A (en)	1995-06-01	1998-02-17	University Of Iowa Research Foundation	Enzyme-surfactant ion-pair complex catalyzed reactions in organic solvents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR39628E (fr) *	1931-01-12	1932-01-22	Ig Farbenindustrie Ag	Procédé pour l'activation des protéases
US2567747A (en) *	1948-03-18	1951-09-11	Wallerstein Co Inc	Stabilization of enzyme preparations
US3940420A (en) *	1974-07-15	1976-02-24	Pierce Chemical Company	Compound, dithiobis-(succinimidyl propionate)
US4609625A (en) *	1983-11-14	1986-09-02	Owens-Illinois, Inc.	Process for the production of modified proteins and product thereof
FR2580666B1 (fr) *	1985-04-19	1988-01-15	Elf Aquitaine	Perfectionnement a l'immobilisation d'enzymes

1988
- 1988-06-23 ES ES88401579T patent/ES2056946T3/es not_active Expired - Lifetime
- 1988-06-23 EP EP88401579A patent/EP0300849B1/fr not_active Expired - Lifetime
- 1988-06-23 DE DE88401579T patent/DE3881774T2/de not_active Expired - Fee Related
- 1988-06-27 NO NO882836A patent/NO302184B1/no unknown
- 1988-06-28 PT PT87858A patent/PT87858B/pt not_active IP Right Cessation
- 1988-06-29 CA CA000570714A patent/CA1331571C/fr not_active Expired - Fee Related
- 1988-06-29 US US07/213,093 patent/US4870016A/en not_active Expired - Fee Related
- 1988-06-29 DK DK359788A patent/DK359788A/da not_active Application Discontinuation
- 1988-06-29 JP JP63159557A patent/JP2722205B2/ja not_active Expired - Lifetime
1989
- 1989-10-31 GR GR89300105T patent/GR890300105T1/el unknown

Also Published As

Publication number	Publication date
PT87858A (pt)	1988-07-01
EP0300849A1 (fr)	1989-01-25
PT87858B (pt)	1992-10-30
JP2722205B2 (ja)	1998-03-04
EP0300849B1 (fr)	1993-06-16
NO882836D0 (no)	1988-06-27
ES2056946T3 (es)	1994-10-16
DE3881774T2 (de)	1993-11-18
DK359788D0 (da)	1988-06-29
DK359788A (da)	1988-12-31
CA1331571C (fr)	1994-08-23
JPS6467185A (en)	1989-03-13
DE3881774D1 (de)	1993-07-22
GR890300105T1 (en)	1989-10-31
NO882836L (no)	1989-01-02
US4870016A (en)	1989-09-26

Publication	Publication Date	Title
Hanson et al.	1976	[42] Crystalline leucine aminopeptidase from lens (α-aminoacyl-peptide hydrolase; EC 3.4. 11.1)
Snyder et al.	1981	Electrostatic influence of local cysteine environments on disulfide exchange kinetics
Horiuchi et al.	1989	Purification and properties of fructosyl-amino acid oxidase from Corynebacterium sp. 2-4-1
CN115298320B (zh)	2026-05-01	蛋白质的交联方法
JPH04504872A (ja)	1992-08-27	ポリペプチドの修飾に使用するための活性ポリアルキレンオキシドカーボネート
Matheis et al.	1984	Peroxidase-catalyzed cross linking of proteins
Naslin et al.	1973	A Study of Several Bonds Hypersensitive to Proteases in a Complex Flavohemoenzyme, Yeast Cytochrome b2: Modification of Their Reactivity with Ligand‐Induced Conformational Transitions
EP1047445A4 (en)	2001-09-12	MODIFIED ENZYMES AND THEIR USE FOR PEPTIDE SYNTHESIS
Zhang et al.	1999	Thermal stability and thermodynamic analysis of native and methoxypolyethylene glycol modified trypsin
JPH05222100A (ja)	1993-08-31	還元型ケラチンペプタイドの製造方法
US4870016A (en)	1989-09-26	Process of chemical modfication of protides and the products thus modified
He et al.	2000	Kinetic study of thermal inactivation for native and methoxypolyethylene glycol modified trypsin
Kühlmeyer et al.	2003	Stabilisation of enzymes with polyvinylsaccharides I: physical stabilisation of horseradish peroxidase
US9206224B2 (en)	2015-12-08	Method for synthesizing proteins
JPH08165298A (ja)	1996-06-25	可溶性蛋白質の製造法
EP2314646A1 (en)	2011-04-27	Diselenide-resins for oxidative protein folding
WO1995022907A1 (en)	1995-08-31	Method for isolating of wheyproteins
Heilmann et al.	1975	On the role of tryptophan residues in the mechanism of action of glyceraldehyde-3-phosphate dehydrogenase as tested by specific modification
Kapoor	1996	How to cross-link proteins
Kitchell et al.	1982	A synthetic 13-residue peptide designed to resemble the primary binding site of the basic pancreatic trypsin inhibitor
Silver et al.	1974	Inactivation of aminoacyl-tRNA synthetases by amino acid chloromethylketones
FEENEY	2018	The Non-Bond Splitting Mechanism of Action of Inhibitors of Proteolytic Enzymes-the Conservative Interpretation
Garcia et al.	1998	Chemical modification of horseradish peroxidase with several methoxypolyethylene glycols
Shahbaz Mohammadi et al.	2008	Rapid one-step separation and purification of recombinant phenylalanine dehydrogenase in aqueous two-phase systems
Genov et al.	1978	CIRCULAR DICHROISM STUDIES ON NATIVE AND PHENYLMETHANESULFONYL‐MESENTERICOPEPTIDASE: Denaturation in the Presence of Urea