NO304832B1 - Aminokinolonderivater samt middel mot HIV - Google Patents

Aminokinolonderivater samt middel mot HIV

Info

Publication number
NO304832B1
NO304832B1 NO931867A NO931867A NO304832B1 NO 304832 B1 NO304832 B1 NO 304832B1 NO 931867 A NO931867 A NO 931867A NO 931867 A NO931867 A NO 931867A NO 304832 B1 NO304832 B1 NO 304832B1
Authority
NO
Norway
Prior art keywords
aminokinolone
derivatives
hiv agents
hiv
agents
Prior art date
Application number
NO931867A
Other languages
English (en)
Norwegian (no)
Other versions
NO931867L (no
NO931867D0 (no
Inventor
Tomio Kimura
Tetsushi Katsube
Original Assignee
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries filed Critical Ube Industries
Publication of NO931867D0 publication Critical patent/NO931867D0/no
Publication of NO931867L publication Critical patent/NO931867L/no
Publication of NO304832B1 publication Critical patent/NO304832B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO931867A 1992-05-27 1993-05-24 Aminokinolonderivater samt middel mot HIV NO304832B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15891292 1992-05-27

Publications (3)

Publication Number Publication Date
NO931867D0 NO931867D0 (no) 1993-05-24
NO931867L NO931867L (no) 1993-11-29
NO304832B1 true NO304832B1 (no) 1999-02-22

Family

ID=15682065

Family Applications (1)

Application Number Title Priority Date Filing Date
NO931867A NO304832B1 (no) 1992-05-27 1993-05-24 Aminokinolonderivater samt middel mot HIV

Country Status (18)

Country Link
US (2) US5519016A (2)
EP (1) EP0572259A1 (2)
KR (1) KR100266305B1 (2)
CN (1) CN1042936C (2)
AU (1) AU656859B2 (2)
CA (1) CA2096998A1 (2)
CZ (1) CZ99693A3 (2)
FI (1) FI932412L (2)
HU (1) HUT64051A (2)
ID (1) ID20476A (2)
IL (1) IL105806A (2)
MX (1) MX9303158A (2)
NO (1) NO304832B1 (2)
NZ (1) NZ247720A (2)
PH (1) PH31078A (2)
RU (1) RU2124510C1 (2)
TW (1) TW234121B (2)
ZA (1) ZA933732B (2)

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DE4425660A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 7-substituierte 1-[4-(1H-1,2,4-triazol-1-yl-methyl)phenyl] substituierte Chinoloncarbonsäuren
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US6001863A (en) * 1996-11-26 1999-12-14 Warner-Lambert Company Isothiazolones
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EP1362843B1 (en) * 1998-08-12 2006-06-14 Ihara Chemical Industry Co., Ltd. N-cyclopropyl-2-difluoromethoxy-3-bromoaniline and intermediate used for production thereof
ES2216606T3 (es) * 1998-12-21 2004-10-16 Aventis Pharma S.A. Derivados de la benzo-1,8-naftiridina.
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DE602005023717D1 (de) * 2004-03-10 2010-11-04 Usa Chinolin-4-one als inhibitoren der retroviralen integrase zur behandlung von hiv, aids und aids-related complex (arc)
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CN101120004A (zh) * 2004-11-11 2008-02-06 艾其林医药公司 用作抗感染剂的8a,9-二氢-4a-h-异噻唑[5,4-b]喹啉-3,4-二酮及相关化合物
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JP5143000B2 (ja) 2005-07-27 2013-02-13 アキリオン ファーマシューティカルズ,インコーポレーテッド 抗感染症薬としての8−メトキシ−9H−イソチアゾロ[5,4−b]キノリン−3,4−ジオンおよび関連化合物
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CN101045724B (zh) * 2006-03-28 2011-08-17 宝洁公司 用于制备喹诺酮中间体的偶联方法
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CN102344457B (zh) * 2007-09-12 2015-07-22 杏林制药株式会社 作为 gsk-3 抑制剂的螺环状氨基喹诺酮
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Also Published As

Publication number Publication date
CN1086515A (zh) 1994-05-11
MX9303158A (es) 1994-04-29
HUT64051A (en) 1993-11-29
US5688791A (en) 1997-11-18
ZA933732B (en) 1993-12-15
IL105806A (en) 1998-02-22
US5519016A (en) 1996-05-21
KR100266305B1 (ko) 2000-09-15
CA2096998A1 (en) 1993-11-28
CZ99693A3 (en) 1993-12-15
AU656859B2 (en) 1995-02-16
IL105806A0 (en) 1993-09-22
NO931867L (no) 1993-11-29
NO931867D0 (no) 1993-05-24
EP0572259A1 (en) 1993-12-01
RU2124510C1 (ru) 1999-01-10
CN1042936C (zh) 1999-04-14
PH31078A (en) 1998-02-05
FI932412A0 (fi) 1993-05-26
AU3981593A (en) 1993-12-02
KR930023360A (ko) 1993-12-18
ID20476A (id) 1998-12-24
TW234121B (2) 1994-11-11
HU9301536D0 (en) 1993-09-28
NZ247720A (en) 1994-09-27
FI932412A7 (fi) 1993-11-28
FI932412L (fi) 1993-11-28

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