NO307784B1 - Polysubstituerte 3-acylamino-5-fenyl-1,4-benzodiazepin-2-on- derivater, farmasøytiske blandinger inneholdende dem og mellomprodukter for fremstilling derav - Google Patents
Polysubstituerte 3-acylamino-5-fenyl-1,4-benzodiazepin-2-on- derivater, farmasøytiske blandinger inneholdende dem og mellomprodukter for fremstilling deravInfo
- Publication number
- NO307784B1 NO307784B1 NO950537A NO950537A NO307784B1 NO 307784 B1 NO307784 B1 NO 307784B1 NO 950537 A NO950537 A NO 950537A NO 950537 A NO950537 A NO 950537A NO 307784 B1 NO307784 B1 NO 307784B1
- Authority
- NO
- Norway
- Prior art keywords
- benzodiazepin
- polysubstituted
- acylamino
- intermediates
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9401642A FR2716194B1 (fr) | 1994-02-14 | 1994-02-14 | Dérivés de 3-acylamino-5-phényl-1,4-benzodiazépin-2-one polysubstitués, leur procédé de préparation et les compositions pharmaceutiques les contenant. |
| FR9408665A FR2716195B1 (fr) | 1994-02-14 | 1994-07-12 | Dérivés de 3-acylamino-5-phényl-1,4-benzodiazépin-2-one polysubstitués, leur procédé de préparation et les compositions pharmaceutiques les contenant. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO950537D0 NO950537D0 (no) | 1995-02-13 |
| NO950537L NO950537L (no) | 1995-08-15 |
| NO307784B1 true NO307784B1 (no) | 2000-05-29 |
Family
ID=26230950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO950537A NO307784B1 (no) | 1994-02-14 | 1995-02-13 | Polysubstituerte 3-acylamino-5-fenyl-1,4-benzodiazepin-2-on- derivater, farmasøytiske blandinger inneholdende dem og mellomprodukter for fremstilling derav |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5719143A (no) |
| EP (1) | EP0667344A1 (no) |
| JP (1) | JPH07300467A (no) |
| KR (1) | KR950032145A (no) |
| CN (1) | CN1053438C (no) |
| AU (1) | AU692202B2 (no) |
| CA (1) | CA2142411A1 (no) |
| FI (1) | FI950625A7 (no) |
| FR (1) | FR2716195B1 (no) |
| HU (1) | HUT70050A (no) |
| IL (1) | IL112589A (no) |
| NO (1) | NO307784B1 (no) |
| NZ (1) | NZ270478A (no) |
| PL (1) | PL179904B1 (no) |
| TW (1) | TW427982B (no) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6635632B1 (en) | 1996-12-23 | 2003-10-21 | Athena Neurosciences, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| US6683075B1 (en) | 1996-12-23 | 2004-01-27 | Athena Neurosciences, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use |
| US6569851B1 (en) | 1998-06-22 | 2003-05-27 | Elan Pharmaceutials, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| US6552013B1 (en) | 1998-06-22 | 2003-04-22 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| US6958330B1 (en) | 1998-06-22 | 2005-10-25 | Elan Pharmaceuticals, Inc. | Polycyclic α-amino-ε-caprolactams and related compounds |
| US6509331B1 (en) | 1998-06-22 | 2003-01-21 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| US6774125B2 (en) | 1998-06-22 | 2004-08-10 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| US6528505B1 (en) | 1998-06-22 | 2003-03-04 | Elan Pharmaceuticals, Inc. | Cyclic amino acid compounds pharmaceutical compositions comprising same and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| GB9920872D0 (en) | 1999-09-04 | 1999-11-10 | Glaxo Group Ltd | Benzophenones as inhibitors of reverse transcriptase |
| GB0011092D0 (en) * | 2000-05-08 | 2000-06-28 | Black James Foundation | Gastrin and cholecystokinin receptor ligands (III) |
| US20040167146A1 (en) * | 2002-01-22 | 2004-08-26 | Karen Jackson | Method of treatment |
| US6713470B2 (en) * | 2002-01-22 | 2004-03-30 | Ml Laboratories Plc | Method of treatment |
| US20040043990A1 (en) * | 2002-04-09 | 2004-03-04 | Karen Jackson | Method of treatment |
| GB0221923D0 (en) * | 2002-09-20 | 2002-10-30 | Arrow Therapeutics Ltd | Chemical compounds |
| AU2003267587B2 (en) | 2002-09-20 | 2010-05-20 | Arrow Therapeutics Limited | Benzodiazepine derivatives and pharmaceutical compositions containing them |
| EP1734892B1 (en) * | 2004-03-18 | 2011-03-02 | Contipi Ltd. | Apparatus for the treatment of feminine pelvic organ prolapse |
| EA010888B1 (ru) | 2004-05-25 | 2008-12-30 | Пфайзер Продактс, Инк. | Тетраазабензо[е]азуленовые производные и их аналоги |
| WO2010067233A1 (en) | 2008-12-08 | 2010-06-17 | Pfizer Inc. | 1,2,4 triazolo [4, 3 -a] [1,5] benzodiazepin-5 (6h) -ones as agonists of the cholecystokinin-1 receptor (cck-ir) |
| CN102924448B (zh) * | 2012-09-19 | 2015-02-25 | 渤海大学 | 生物碱cryptolepine类似物吲哚并喹啉酸化合物及制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5023532B2 (no) * | 1971-09-09 | 1975-08-08 | ||
| CA1332410C (en) * | 1984-06-26 | 1994-10-11 | Roger M. Freidinger | Benzodiazepine analogs |
| FR2641280B1 (fr) * | 1988-12-29 | 1994-01-21 | Roussel Uclaf | Nouveaux derives de la 2,4-dioxo 2,3,4,5-tetrahydro 1h-1,5-benzodiazepine, leur procede de preparation et leur application comme medicaments |
-
1994
- 1994-07-12 FR FR9408665A patent/FR2716195B1/fr not_active Expired - Fee Related
-
1995
- 1995-02-09 IL IL11258995A patent/IL112589A/xx not_active IP Right Cessation
- 1995-02-10 AU AU11668/95A patent/AU692202B2/en not_active Ceased
- 1995-02-10 NZ NZ270478A patent/NZ270478A/en unknown
- 1995-02-13 NO NO950537A patent/NO307784B1/no unknown
- 1995-02-13 JP JP7023848A patent/JPH07300467A/ja not_active Withdrawn
- 1995-02-13 CA CA002142411A patent/CA2142411A1/en not_active Abandoned
- 1995-02-13 FI FI950625A patent/FI950625A7/fi unknown
- 1995-02-13 EP EP95400293A patent/EP0667344A1/fr not_active Withdrawn
- 1995-02-13 CN CN95101504A patent/CN1053438C/zh not_active Expired - Fee Related
- 1995-02-13 KR KR1019950002560A patent/KR950032145A/ko not_active Ceased
- 1995-02-13 HU HU9500434A patent/HUT70050A/hu unknown
- 1995-02-14 US US08/390,770 patent/US5719143A/en not_active Expired - Fee Related
- 1995-02-14 PL PL95307255A patent/PL179904B1/pl unknown
- 1995-02-16 TW TW084101431A patent/TW427982B/zh active
-
1997
- 1997-11-20 US US08/975,003 patent/US5798353A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR950032145A (ko) | 1995-12-20 |
| JPH07300467A (ja) | 1995-11-14 |
| US5798353A (en) | 1998-08-25 |
| IL112589A (en) | 2000-06-01 |
| FR2716195A1 (fr) | 1995-08-18 |
| HU9500434D0 (en) | 1995-03-28 |
| FI950625A0 (fi) | 1995-02-13 |
| NO950537L (no) | 1995-08-15 |
| PL307255A1 (en) | 1995-08-21 |
| US5719143A (en) | 1998-02-17 |
| FR2716195B1 (fr) | 1996-06-21 |
| CA2142411A1 (en) | 1995-08-15 |
| FI950625L (fi) | 1995-08-15 |
| TW427982B (en) | 2001-04-01 |
| AU1166895A (en) | 1995-08-24 |
| PL179904B1 (pl) | 2000-11-30 |
| IL112589A0 (en) | 1995-05-26 |
| FI950625A7 (fi) | 1995-08-15 |
| HUT70050A (en) | 1995-09-28 |
| NO950537D0 (no) | 1995-02-13 |
| EP0667344A1 (fr) | 1995-08-16 |
| AU692202B2 (en) | 1998-06-04 |
| NZ270478A (en) | 1996-12-20 |
| CN1126207A (zh) | 1996-07-10 |
| CN1053438C (zh) | 2000-06-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20001409D0 (no) | Karboksamidotiazolderivater, fremgangsmåte for fremstilling derav og farmasøytiske blandinger | |
| HUP0000721A3 (en) | Gemcitabine derivatives, process for their preparation and pharmaceutical compositions containing them | |
| NO981817L (no) | Indolin-2-on-derivater, fremgangsmÕte for fremstilling av dem og farmas÷ytiske blandinger inneholdende dem | |
| HUP9901086A3 (en) | Arylsulfonylaminobenzene derivatives, pharmaceutical compositions containing them and their use for producing pharmaceutical compositions | |
| FI973039A7 (fi) | Uusia farnesyylitransferaasin inhibiittoreita, niiden valmistus ja niitä sisältäviä farmaseuttisia koostumuksia | |
| FI973279A7 (fi) | Uudet farnesyylitransferaasin inhibiittorit, niiden valmistus ja niitä sisältävät farmaseuttiset koostumukset | |
| EE04498B1 (et) | Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon | |
| FI963566A7 (fi) | Uusia piperatsiinijohdoksia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä koostumuksia | |
| FI953898A7 (fi) | Glysiiniamidijohdannaisia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä lääkeaineita | |
| NO950537L (no) | Polysubstituerte 3-acylamino-5-fenyl-1,4-benzodiazepin-2-on-derivater, fremgangsmåter for fremstilling derav og farmasöytiske blandinger inneholdende dem | |
| DK1112266T3 (da) | Substituerede 4-amino-2-arylpyrimidiner, fremstilling og anvendelse deraf og farmaceutiske præparater indeholdende dem | |
| NO307092B1 (no) | Sordaridin-derivater, anvendelse derav og farmasoeytisk blanding | |
| FI952550A7 (fi) | Uudet N-pyridyylikarboksamidit ja johdannaiset, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset | |
| HUP9904694A3 (en) | Spiropyrrolidine derivatives, their use and pharmaceutical compositions containing them | |
| FI943688L (fi) | Uudet 11-bentsaldoksiimi-17beta-metoksi-27alfa-metoksi-metyyli-estradieenijohdannaiset, menetelmät niiden valmistamiseksi ja näitä sisältävät lääkeaineet | |
| EE03825B1 (et) | 2-tsüanoiminoimidasooli derivaadid, nende valmistamismeetod, kasutamine ja farmatseutilised kompositsioonid | |
| NO955320D0 (no) | Substituerte 4-fenyltiazolderivater, fremgangsmåte for fremstilling derav og farmasöytiske blandinger som inneholder dem | |
| HU9700955D0 (en) | Substituted 2-naphtoylguanidine derivatives, their production, their use and pharmaceutical compositions containing them | |
| FI960316L (fi) | Oksatiolaanit, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset | |
| EE03996B1 (et) | Farmatseutilised kompositsioonid, nende valmistamismeetod ja kasutamine | |
| HUP0000203A3 (en) | Naphthyl derivatives, pharmaceutical compositions containing them and intermediates | |
| HUP9800631A3 (en) | 4-aminotetrahydrobenzisoxazole or -isothiazole derivatives, pharmaceutical compositions containing them and their use for the preparation of pharmaceutical compositions | |
| HUP9802590A3 (en) | Indan-, benzothiophene-, benzofuran- and indolesulfonamide derivatives, their use and pharmaceutical compositions containing them | |
| HUP9602774A3 (en) | Benzoxazepine derivatives, pharmaceutical compositions containing them and intermediates | |
| DK0794184T3 (da) | 6-Methoxy-1H-benzotriazol-5-carboxamidderivater, fremgangsmåde til fremstilling deraf og lægemidler indeholdende dem |