NO308508B1 - Anvendelse av levobupivacaine i enantiomert overskudd - Google Patents

Anvendelse av levobupivacaine i enantiomert overskudd

Info

Publication number: NO308508B1
Authority: NO; Norway
Prior art keywords: levobupivacaine; enantiomeric excess; enantiomeric; excess; anaesthetic
Prior art date: 1993-10-13

Application number

NO961479A

Other languages

English (en)

Norwegian (no)

Other versions

NO961479L (no

NO961479D0 (no

Inventor

Hazel Judith Bardsley

Robert William Gristwood

Original Assignee

Darwin Discovery Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-13

Filing date

1996-04-12

Publication date

2000-09-25

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26303667&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO308508(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1993-10-13 Priority claimed from GB939321061A external-priority patent/GB9321061D0/en

1994-04-22 Priority claimed from GB9408014A external-priority patent/GB9408014D0/en

1996-04-12 Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd

1996-04-12 Publication of NO961479D0 publication Critical patent/NO961479D0/no

1996-06-11 Publication of NO961479L publication Critical patent/NO961479L/no

2000-09-25 Publication of NO308508B1 publication Critical patent/NO308508B1/no

Links

LEBVLXFERQHONN-INIZCTEOSA-N levobupivacaine Chemical compound CCCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-INIZCTEOSA-N 0.000 title abstract 2
229960004288 levobupivacaine Drugs 0.000 title abstract 2
230000003444 anaesthetic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Neurology (AREA)
Anesthesiology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO961479A 1993-10-13 1996-04-12 Anvendelse av levobupivacaine i enantiomert overskudd NO308508B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB939321061A GB9321061D0 (en)	1993-10-13	1993-10-13	Analgestic agent and its use
GB9408014A GB9408014D0 (en)	1994-04-22	1994-04-22	Analgesic agent and its use
PCT/GB1994/002249 WO1995010277A1 (en)	1993-10-13	1994-10-13	Analgesic agent and its use

Publications (3)

Publication Number	Publication Date
NO961479D0 NO961479D0 (no)	1996-04-12
NO961479L NO961479L (no)	1996-06-11
NO308508B1 true NO308508B1 (no)	2000-09-25

Family

ID=26303667

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO961479A NO308508B1 (no)	1993-10-13	1996-04-12	Anvendelse av levobupivacaine i enantiomert overskudd

Country Status (15)

Country	Link
US (1)	US5708011A (de)
EP (2)	EP0727210B1 (de)
JP (2)	JPH09503778A (de)
KR (1)	KR100365979B1 (de)
CN (1)	CN1074920C (de)
AT (2)	ATE150643T1 (de)
AU (1)	AU694453B2 (de)
DE (2)	DE69402330T2 (de)
DK (2)	DK0723445T3 (de)
ES (2)	ES2170179T3 (de)
GR (1)	GR3023289T3 (de)
HK (1)	HK1006420A1 (de)
NO (1)	NO308508B1 (de)
PT (1)	PT727210E (de)
WO (1)	WO1995010277A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9507677D0 (en) *	1995-04-13	1995-05-31	Chiroscience Ltd	Pharmaceutical formulation and dose
GB9321061D0 (en) *	1993-10-13	1993-12-01	Chiroscience Ltd	Analgestic agent and its use
CA2216583C (en) *	1995-04-13	2007-10-30	Chiroscience Limited	Levobupivacaine and its use as an anaesthetic in pregnant women
GB9704370D0 (en) *	1997-03-03	1997-04-23	Chiroscience Ltd	Levobupivacaine and its use
GB9704351D0 (en) *	1997-03-03	1997-04-23	Chiroscience Ltd	Levobupivacaine and its use
GB9704352D0 (en) *	1997-03-03	1997-04-23	Chiroscience Ltd	Levobupivacaine and its use
CA2294950C (en) *	1997-07-21	2009-04-07	Darwin Discovery Limited	Levobupivacaine and its use
ATE239474T1 (de) *	1997-07-22	2003-05-15	Darwin Discovery Ltd	Verwendung von levobupivacain
US6045824A (en)	1997-09-18	2000-04-04	Skyepharma Inc.	Sustained-release liposomal anesthetic compositions
AU752802C (en) *	1997-11-14	2006-04-13	Pacira Pharmaceuticals, Inc.	Production of multivesicular liposomes
BR9814883A (pt) *	1997-11-19	2000-10-03	Darwin Discovery Ltd	Formulação anestésica
WO2000003660A1 (en)	1998-07-17	2000-01-27	Skyepharma, Inc.	Biodegradable compositions for the controlled release of encapsulated substances
BR0002246A (pt) *	2000-04-06	2003-04-15	Cristalia Prod Quimicos Farm	Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis
WO2002096368A2 (en) *	2001-05-31	2002-12-05	Skyepharma Inc.	Encapsulation of nanosuspensions in liposomes and microspheres
ATE507816T1 (de) *	2001-11-14	2011-05-15	Durect Corp	Injizierbare depotzusammensetzungen und deren verwendung
US20070196415A1 (en) *	2002-11-14	2007-08-23	Guohua Chen	Depot compositions with multiple drug release rate controls and uses thereof
AU2002359407B2 (en) *	2001-11-14	2008-02-28	Durect Corporation	Catheter injectable depot compositions and uses thereof
US20040001889A1 (en)	2002-06-25	2004-01-01	Guohua Chen	Short duration depot formulations
CN1684663A (zh) *	2002-07-31	2005-10-19	阿尔萨公司	可注射的多模式聚合物储库组合物以及其用途
WO2004012703A1 (en) *	2002-07-31	2004-02-12	Alza Corporation	Injectable depot compositions and uses thereof
US20060142234A1 (en) *	2004-12-23	2006-06-29	Guohua Chen	Injectable non-aqueous suspension
WO2010065930A1 (en) *	2008-12-04	2010-06-10	The Board Of Trustees Of The Leland Stanford Junior University	Methods and compositions for treating or preventing narcotic withdrawal symptoms
WO2015088990A1 (en)	2013-12-09	2015-06-18	Durect Corporation	Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
CN106214670B (zh) *	2016-07-25	2020-12-29	上海璃道医药科技有限公司	酰胺类药物的用途
WO2021146215A1 (en)	2020-01-13	2021-07-22	Durect Corporation	Sustained release drug delivery systems with reduced impurities and related methods
CA3203561A1 (en)	2021-01-12	2022-07-21	Adrian Neil Verity	Sustained release drug delivery systems and related methods
US11033495B1 (en)	2021-01-22	2021-06-15	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en)	2021-01-22	2022-06-14	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
US12151024B2 (en)	2021-01-22	2024-11-26	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en)	2021-01-22	2022-03-22	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
US12285419B2 (en)	2021-10-14	2025-04-29	Pacira Pharmaceuticals, Inc.	Bupivacaine multivesicular liposome formulations and uses thereof
US12251472B1 (en)	2024-05-20	2025-03-18	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
US12156940B1 (en)	2024-05-20	2024-12-03	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
US12280149B1 (en)	2024-05-20	2025-04-22	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4695576A (en) *	1984-07-09	1987-09-22	Astra Lake Medel Aktiebolag	L-N-n-propylpipecolic acid-2,6-xylidide
CA2216583C (en) *	1995-04-13	2007-10-30	Chiroscience Limited	Levobupivacaine and its use as an anaesthetic in pregnant women

1994
- 1994-10-13 AU AU78594/94A patent/AU694453B2/en not_active Expired
- 1994-10-13 AT AT94929596T patent/ATE150643T1/de active
- 1994-10-13 JP JP7511489A patent/JPH09503778A/ja active Pending
- 1994-10-13 DK DK94929596.8T patent/DK0723445T3/da active
- 1994-10-13 CN CN94193782A patent/CN1074920C/zh not_active Expired - Lifetime
- 1994-10-13 DK DK96106830T patent/DK0727210T3/da active
- 1994-10-13 US US08/640,930 patent/US5708011A/en not_active Expired - Lifetime
- 1994-10-13 ES ES96106830T patent/ES2170179T3/es not_active Expired - Lifetime
- 1994-10-13 AT AT96106830T patent/ATE210982T1/de active
- 1994-10-13 WO PCT/GB1994/002249 patent/WO1995010277A1/en not_active Ceased
- 1994-10-13 DE DE69402330T patent/DE69402330T2/de not_active Expired - Lifetime
- 1994-10-13 EP EP96106830A patent/EP0727210B1/de not_active Expired - Lifetime
- 1994-10-13 DE DE69429536T patent/DE69429536T2/de not_active Expired - Lifetime
- 1994-10-13 PT PT96106830T patent/PT727210E/pt unknown
- 1994-10-13 KR KR1019960701864A patent/KR100365979B1/ko not_active Expired - Lifetime
- 1994-10-13 HK HK98105740A patent/HK1006420A1/en not_active IP Right Cessation
- 1994-10-13 ES ES94929596T patent/ES2101578T3/es not_active Expired - Lifetime
- 1994-10-13 EP EP94929596A patent/EP0723445B1/de not_active Expired - Lifetime
1996
- 1996-04-12 NO NO961479A patent/NO308508B1/no not_active IP Right Cessation
1997
- 1997-04-29 GR GR970400954T patent/GR3023289T3/el unknown
2006
- 2006-05-17 JP JP2006137795A patent/JP2006213736A/ja active Pending

Also Published As

Publication number	Publication date
AU7859494A (en)	1995-05-04
DE69429536T2 (de)	2002-06-20
DK0723445T3 (da)	1997-10-06
AU694453B2 (en)	1998-07-23
ES2170179T3 (es)	2002-08-01
JPH09503778A (ja)	1997-04-15
WO1995010277A1 (en)	1995-04-20
EP0723445A1 (de)	1996-07-31
DE69402330D1 (de)	1997-04-30
NO961479L (no)	1996-06-11
ES2101578T3 (es)	1997-07-01
EP0727210A2 (de)	1996-08-21
CN1133010A (zh)	1996-10-09
PT727210E (pt)	2002-06-28
KR100365979B1 (ko)	2003-07-22
ATE150643T1 (de)	1997-04-15
EP0727210B1 (de)	2001-12-19
JP2006213736A (ja)	2006-08-17
EP0723445B1 (de)	1997-03-26
CN1074920C (zh)	2001-11-21
GR3023289T3 (en)	1997-07-30
US5708011A (en)	1998-01-13
NO961479D0 (no)	1996-04-12
DE69402330T2 (de)	1997-07-03
DE69429536D1 (de)	2002-01-31
EP0727210A3 (de)	1998-03-04
DK0727210T3 (da)	2002-04-15
HK1006420A1 (en)	1999-02-26
ATE210982T1 (de)	2002-01-15

Legal Events

Date	Code	Title	Description
2014-10-20	MK1K	Patent expired

Publication	Publication Date	Title
ES2101578T3 (es)	1997-07-01	Agente analgesico y su utilizacion.
DK0638088T3 (da)	2005-04-25	Human/porcin faktor VIII-hybrid
FI914065A0 (fi)	1991-08-28	Serotonin-5ht1a-agonister.
PT91553A (pt)	1990-03-08	Processo de preparacao de uma composicao contendo morfina
ATE176589T1 (de)	1999-02-15	Kosmetische und dermatologische zubereitungen mit einem gehalt an delta-aminolävulinsäure
FI19992420L (fi)	1999-11-10	Mikrobifytaasin kloonaus ja ilmentäminen
KR970706824A (ko)	1997-12-01	붕산 에스테르 및 붕산 화합물, 이의 합성 방법 및 용도(boronic ester and acid compounds, synthesis and uses)
MX9302931A (es)	1994-02-28	Nuevas 4-aza-5&-colestan-onas 7b-substituidas como inhibidores de 5&-reductasa.
FI931336A0 (fi)	1993-03-25	Laekemedel som innehaoller polyhydroximetylenderivat, foerfarande foer deras framstaellning och bruk
FI935944A0 (fi)	1993-12-30	Pyratsolopyrimidin- samt pyrimidinylbisfosfonestrar som anti- inflammatorer
ES2179254T3 (es)	2003-01-16	1-poliarilpirazoles plaguicidas.
NO944075L (no)	1994-12-27	Fremgangsmåte for fremstilling av (S)-3-amino-1-substituert pyrrolidiner
DE69417577D1 (de)	1999-05-06	Herstellung von polymerisierungsfähigem dicyclopentadien
DE58906241D1 (de)	1994-01-05	Verwendung von Plasminogen-Aktivator-Inhibitor (PAI-2) zur Immunsuppression.
ATE31295T1 (de)	1987-12-15	Benzoylharnstoffderivate.
DE69208759D1 (de)	1996-04-11	Salze von N-Nitrosophenylhydroxylamin
DE69413112D1 (de)	1998-10-15	5-HT3 Pyrrolopyrazinderivate
DE69317343D1 (de)	1998-04-16	Verwendung eines direkten Inhibitors von Thrombin zur Herstellung eines Arzneimittels mit thrombolytischer Aktivität
DE69131058D1 (de)	1999-05-06	Verwendung einer therapeutischen Zusammensetzung zur Behandlung von Bronchitis
DE69320420D1 (de)	1998-09-24	Benzyl- und Benzhydryl Alkohole
DE68919593D1 (de)	1995-01-12	Verwendung von Zofenopril zur Herstellung von Medikamenten gegen rheumatoide Arthritis.
NO995132D0 (no)	1999-10-21	Fremgangsmåte for reduksjon av fibrinogen
NO974551L (no)	1998-04-06	Bruk av sulbutiamin for å fremskaffe farmasöytiske sammensetninger nyttige i behandling av visse psykomotoriske- og psyko-intellektuelle sykdommer
ATE100710T1 (de)	1994-02-15	Eperisone als hypotonikum.
ITMI921866A1 (it)	1994-01-30	Uso dell'oxatomide come agente antitosse