NO310011B1 - Oftalmisk preparat og fremgangsmåte for desinfeksjon av kontaktlinser, samt fremgangsmåte for preservering av et slikt preparat - Google Patents
Oftalmisk preparat og fremgangsmåte for desinfeksjon av kontaktlinser, samt fremgangsmåte for preservering av et slikt preparat Download PDFInfo
- Publication number
- NO310011B1 NO310011B1 NO951989A NO951989A NO310011B1 NO 310011 B1 NO310011 B1 NO 310011B1 NO 951989 A NO951989 A NO 951989A NO 951989 A NO951989 A NO 951989A NO 310011 B1 NO310011 B1 NO 310011B1
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- methyl
- saturated
- ophthalmic
- unsaturated alkyl
- Prior art date
Links
- 230000000249 desinfective effect Effects 0.000 title claims abstract description 8
- 238000002360 preparation method Methods 0.000 title claims description 59
- 238000000034 method Methods 0.000 title claims description 27
- 150000001875 compounds Chemical class 0.000 claims description 48
- 238000004659 sterilization and disinfection Methods 0.000 claims description 14
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 13
- 229920006395 saturated elastomer Polymers 0.000 claims description 12
- 125000004417 unsaturated alkyl group Chemical group 0.000 claims description 12
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 8
- 150000003839 salts Chemical class 0.000 claims description 8
- 125000004171 alkoxy aryl group Chemical group 0.000 claims description 6
- 125000002877 alkyl aryl group Chemical group 0.000 claims description 6
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims description 6
- 230000000845 anti-microbial effect Effects 0.000 claims description 5
- 239000004599 antimicrobial Substances 0.000 claims description 5
- -1 heptadec-8-enyl Chemical group 0.000 claims description 5
- 239000003937 drug carrier Substances 0.000 claims description 4
- 238000011109 contamination Methods 0.000 claims description 3
- 230000000813 microbial effect Effects 0.000 claims description 3
- 125000002889 tridecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 6
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 claims 3
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 claims 3
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 3
- 125000002960 margaryl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 3
- 125000002958 pentadecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 3
- 125000005065 undecenyl group Chemical group C(=CCCCCCCCCC)* 0.000 claims 3
- 125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 3
- 238000004140 cleaning Methods 0.000 abstract description 15
- 239000000203 mixture Substances 0.000 abstract description 13
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 24
- 239000000243 solution Substances 0.000 description 16
- 239000000645 desinfectant Substances 0.000 description 8
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 6
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- HEDRZPFGACZZDS-MICDWDOJSA-N Trichloro(2H)methane Chemical compound [2H]C(Cl)(Cl)Cl HEDRZPFGACZZDS-MICDWDOJSA-N 0.000 description 6
- 238000009472 formulation Methods 0.000 description 6
- 239000003755 preservative agent Substances 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 238000004321 preservation Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000004094 surface-active agent Substances 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 239000013043 chemical agent Substances 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 208000001860 Eye Infections Diseases 0.000 description 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 description 3
- 230000000843 anti-fungal effect Effects 0.000 description 3
- 208000011323 eye infectious disease Diseases 0.000 description 3
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 3
- 235000019341 magnesium sulphate Nutrition 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000012044 organic layer Substances 0.000 description 3
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 3
- 235000017557 sodium bicarbonate Nutrition 0.000 description 3
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- UNSAJINGUOTTRA-UHFFFAOYSA-N 3-(3-bromophenyl)prop-2-yn-1-ol Chemical compound OCC#CC1=CC=CC(Br)=C1 UNSAJINGUOTTRA-UHFFFAOYSA-N 0.000 description 2
- 101150041968 CDC13 gene Proteins 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 2
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 2
- 150000001408 amides Chemical class 0.000 description 2
- 125000006295 amino methylene group Chemical group [H]N(*)C([H])([H])* 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 239000006172 buffering agent Substances 0.000 description 2
- IUNMPGNGSSIWFP-UHFFFAOYSA-N dimethylaminopropylamine Chemical compound CN(C)CCCN IUNMPGNGSSIWFP-UHFFFAOYSA-N 0.000 description 2
- NQGIJDNPUZEBRU-UHFFFAOYSA-N dodecanoyl chloride Chemical compound CCCCCCCCCCCC(Cl)=O NQGIJDNPUZEBRU-UHFFFAOYSA-N 0.000 description 2
- 238000000921 elemental analysis Methods 0.000 description 2
- CCGKOQOJPYTBIH-UHFFFAOYSA-N ethenone Chemical compound C=C=O CCGKOQOJPYTBIH-UHFFFAOYSA-N 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 229910001410 inorganic ion Inorganic materials 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 229920001451 polypropylene glycol Polymers 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229940105325 3-dimethylaminopropylamine Drugs 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 206010015946 Eye irritation Diseases 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- HSHXDCVZWHOWCS-UHFFFAOYSA-N N'-hexadecylthiophene-2-carbohydrazide Chemical compound CCCCCCCCCCCCCCCCNNC(=O)c1cccs1 HSHXDCVZWHOWCS-UHFFFAOYSA-N 0.000 description 1
- CJKRXEBLWJVYJD-UHFFFAOYSA-N N,N'-diethylethylenediamine Chemical compound CCNCCNCC CJKRXEBLWJVYJD-UHFFFAOYSA-N 0.000 description 1
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000003732 agents acting on the eye Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000000607 artificial tear Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 150000001642 boronic acid derivatives Chemical class 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 150000001860 citric acid derivatives Chemical class 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000000850 decongestant Substances 0.000 description 1
- 229940124581 decongestants Drugs 0.000 description 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 150000002171 ethylene diamines Chemical class 0.000 description 1
- 231100000013 eye irritation Toxicity 0.000 description 1
- 239000003885 eye ointment Substances 0.000 description 1
- 125000004005 formimidoyl group Chemical group [H]\N=C(/[H])* 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- QOHMWDJIBGVPIF-UHFFFAOYSA-N n',n'-diethylpropane-1,3-diamine Chemical compound CCN(CC)CCCN QOHMWDJIBGVPIF-UHFFFAOYSA-N 0.000 description 1
- VMWJCFLUSKZZDX-UHFFFAOYSA-N n,n-dimethylmethanamine Chemical compound [CH2]N(C)C VMWJCFLUSKZZDX-UHFFFAOYSA-N 0.000 description 1
- 229940049292 n-(3-(dimethylamino)propyl)octadecanamide Drugs 0.000 description 1
- BMZTZTSBZWUIKG-UHFFFAOYSA-N n-[3-(diethylamino)propyl]dodecanamide Chemical compound CCCCCCCCCCCC(=O)NCCCN(CC)CC BMZTZTSBZWUIKG-UHFFFAOYSA-N 0.000 description 1
- TWMFGCHRALXDAR-UHFFFAOYSA-N n-[3-(dimethylamino)propyl]dodecanamide Chemical compound CCCCCCCCCCCC(=O)NCCCN(C)C TWMFGCHRALXDAR-UHFFFAOYSA-N 0.000 description 1
- WWVIUVHFPSALDO-UHFFFAOYSA-N n-[3-(dimethylamino)propyl]octadecanamide Chemical compound CCCCCCCCCCCCCCCCCC(=O)NCCCN(C)C WWVIUVHFPSALDO-UHFFFAOYSA-N 0.000 description 1
- IFYDWYVPVAMGRO-UHFFFAOYSA-N n-[3-(dimethylamino)propyl]tetradecanamide Chemical compound CCCCCCCCCCCCCC(=O)NCCCN(C)C IFYDWYVPVAMGRO-UHFFFAOYSA-N 0.000 description 1
- WDSHHJLKKKNVDS-UHFFFAOYSA-N n-[3-(dimethylamino)propyl]tetradecanamide;phosphoric acid Chemical compound OP(O)(O)=O.CCCCCCCCCCCCCC(=O)NCCCN(C)C WDSHHJLKKKNVDS-UHFFFAOYSA-N 0.000 description 1
- 239000012457 nonaqueous media Substances 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 229940023490 ophthalmic product Drugs 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920001987 poloxamine Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229940082054 sodium bicarbonate / sodium chloride Drugs 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 239000012929 tonicity agent Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof containing the group, wherein Cn means a carbon skeleton not containing a ring; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/12—Non-macromolecular oxygen-containing compounds, e.g. hydrogen peroxide or ozone
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Eyeglasses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/125,629 US5393491A (en) | 1993-09-22 | 1993-09-22 | Use of amidoamines in ophthalmic compositions |
| PCT/US1994/010695 WO1995008266A1 (en) | 1993-09-22 | 1994-09-21 | Use of amidoamines in ophthalmic compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO951989D0 NO951989D0 (no) | 1995-05-19 |
| NO951989L NO951989L (no) | 1995-05-19 |
| NO310011B1 true NO310011B1 (no) | 2001-05-07 |
Family
ID=22420662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO951989A NO310011B1 (no) | 1993-09-22 | 1995-05-19 | Oftalmisk preparat og fremgangsmåte for desinfeksjon av kontaktlinser, samt fremgangsmåte for preservering av et slikt preparat |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5393491A (de) |
| EP (1) | EP0669803B1 (de) |
| JP (1) | JP3073020B2 (de) |
| KR (1) | KR100229962B1 (de) |
| AT (1) | ATE187599T1 (de) |
| AU (1) | AU691836B2 (de) |
| BR (1) | BR9405606A (de) |
| CA (1) | CA2148615C (de) |
| DE (1) | DE69422153T2 (de) |
| DK (1) | DK0669803T3 (de) |
| ES (1) | ES2141843T3 (de) |
| FI (1) | FI109573B (de) |
| GR (1) | GR3032112T3 (de) |
| NO (1) | NO310011B1 (de) |
| NZ (1) | NZ274383A (de) |
| WO (1) | WO1995008266A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5573726A (en) * | 1993-09-22 | 1996-11-12 | Alcon Laboratories, Inc. | Use of amidoamines in ophthalmic compositions |
| US5631005A (en) * | 1994-09-21 | 1997-05-20 | Alcon Laboratories, Inc. | Use of amidoamines in ophthalmic compositions |
| WO1998025649A1 (en) * | 1996-12-13 | 1998-06-18 | Alcon Laboratories, Inc. | Use of low molecular weight amino alcohols in ophthalmic compositions |
| US20040033208A1 (en) * | 2000-12-20 | 2004-02-19 | Cagle Gerald D. | Antifungal compositions containing an antibiotic and one or more amidoamines |
| WO2002049633A2 (en) * | 2000-12-20 | 2002-06-27 | Alcon, Inc. | Use of amidoamines to treat or prevent acanthamoeba and fungal infections |
| US20040115160A1 (en) * | 2002-12-13 | 2004-06-17 | Salamone Joseph C. | Quaternary ammonium esters for disinfection and preservation |
| JP5108234B2 (ja) * | 2005-02-07 | 2012-12-26 | 日本特殊陶業株式会社 | マイクロヒータ及びセンサ |
| US20070053948A1 (en) * | 2005-09-08 | 2007-03-08 | Bausch & Lomb Incorporated | Lens care solution demonstration kit |
| US20070264226A1 (en) * | 2006-05-10 | 2007-11-15 | Karagoezian Hampar L | Synergistically enhanced disinfecting solutions |
| US8691899B2 (en) * | 2007-10-09 | 2014-04-08 | Ethicon, Inc. | Antimicrobial polymer compositions and the use thereof |
| US8163684B2 (en) * | 2008-03-26 | 2012-04-24 | Abbott Medical Optics Inc. | Antimicrobials having polyquaternary ammoniums and alcohol-bearing amidoamines and methods for their use |
| WO2011100994A1 (de) * | 2010-02-19 | 2011-08-25 | Megainpharm Gmbh | Arzneimittel enthaltend myramistin |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2616713A1 (de) * | 1976-04-15 | 1977-11-03 | Hoechst Ag | Desinfektionsmittel |
| US4407791A (en) * | 1981-09-28 | 1983-10-04 | Alcon Laboratories, Inc. | Ophthalmic solutions |
| JPS6151121A (ja) * | 1984-08-21 | 1986-03-13 | Lion Corp | コンタクトレンズ用洗浄剤 |
| US5215976A (en) * | 1991-10-28 | 1993-06-01 | Mona Industries, Inc. | Phospholipids useful as spermicidal agents |
-
1993
- 1993-09-22 US US08/125,629 patent/US5393491A/en not_active Expired - Lifetime
-
1994
- 1994-09-21 AT AT94929286T patent/ATE187599T1/de active
- 1994-09-21 EP EP94929286A patent/EP0669803B1/de not_active Expired - Lifetime
- 1994-09-21 WO PCT/US1994/010695 patent/WO1995008266A1/en not_active Ceased
- 1994-09-21 DK DK94929286T patent/DK0669803T3/da active
- 1994-09-21 ES ES94929286T patent/ES2141843T3/es not_active Expired - Lifetime
- 1994-09-21 CA CA002148615A patent/CA2148615C/en not_active Expired - Lifetime
- 1994-09-21 KR KR1019950702058A patent/KR100229962B1/ko not_active Expired - Lifetime
- 1994-09-21 AU AU78398/94A patent/AU691836B2/en not_active Expired
- 1994-09-21 JP JP07509913A patent/JP3073020B2/ja not_active Expired - Lifetime
- 1994-09-21 NZ NZ274383A patent/NZ274383A/en not_active IP Right Cessation
- 1994-09-21 BR BR9405606A patent/BR9405606A/pt not_active IP Right Cessation
- 1994-09-21 DE DE69422153T patent/DE69422153T2/de not_active Expired - Lifetime
-
1995
- 1995-05-19 FI FI952459A patent/FI109573B/fi not_active IP Right Cessation
- 1995-05-19 NO NO951989A patent/NO310011B1/no not_active IP Right Cessation
-
1999
- 1999-12-16 GR GR990403036T patent/GR3032112T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR100229962B1 (ko) | 1999-11-15 |
| EP0669803A1 (de) | 1995-09-06 |
| DE69422153D1 (de) | 2000-01-20 |
| JPH08503965A (ja) | 1996-04-30 |
| NO951989D0 (no) | 1995-05-19 |
| FI952459A0 (fi) | 1995-05-19 |
| CA2148615C (en) | 2001-01-16 |
| FI109573B (fi) | 2002-09-13 |
| JP3073020B2 (ja) | 2000-08-07 |
| EP0669803B1 (de) | 1999-12-15 |
| KR950703851A (ko) | 1995-11-17 |
| US5393491A (en) | 1995-02-28 |
| DE69422153T2 (de) | 2000-04-06 |
| CA2148615A1 (en) | 1995-03-30 |
| FI952459L (fi) | 1995-05-19 |
| GR3032112T3 (en) | 2000-03-31 |
| HK1011600A1 (en) | 1999-07-16 |
| AU7839894A (en) | 1995-04-10 |
| ATE187599T1 (de) | 2000-01-15 |
| NO951989L (no) | 1995-05-19 |
| NZ274383A (en) | 1995-11-27 |
| BR9405606A (pt) | 1999-05-25 |
| DK0669803T3 (da) | 2000-05-15 |
| WO1995008266A1 (en) | 1995-03-30 |
| AU691836B2 (en) | 1998-05-28 |
| ES2141843T3 (es) | 2000-04-01 |
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