NO310027B1 - Peptid med organbeskyttende aktivitet - Google Patents

Peptid med organbeskyttende aktivitet Download PDF

Info

Publication number: NO310027B1
Authority: NO; Norway
Prior art keywords: peptide; formula; peptide according; amino acid; body weight
Prior art date: 1992-05-30

Application number

NO940299A

Other languages

English (en)

Norwegian (no)

Other versions

NO940299L (no

NO940299D0 (no

Inventor

Predrag Sikiric

Marijan Petek

Sven Seiwerth

Zeljko Grabarevic

Ivo Rotkvic

Marko Duvnjak

Branko Turkovic

Stiepan Mise

Ernest Suchanek

Boris Mildner

Ivan Udovicic

Original Assignee

Predrag Sikiric

Marijan Petek

Sven Seiwerth

Zeljko Grabarevic

Ivo Rotkvic

Marko Duvnjak

Branko Turkovic

Stiepan Mise

Ernest Suchanek

Boris Mildner

Ivan Udovicic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-30

Filing date

1994-01-28

Publication date

2001-05-07

1994-01-28 Application filed by Predrag Sikiric, Marijan Petek, Sven Seiwerth, Zeljko Grabarevic, Ivo Rotkvic, Marko Duvnjak, Branko Turkovic, Stiepan Mise, Ernest Suchanek, Boris Mildner, Ivan Udovicic filed Critical Predrag Sikiric

1994-01-28 Publication of NO940299L publication Critical patent/NO940299L/no

1994-01-28 Publication of NO940299D0 publication Critical patent/NO940299D0/no

2001-05-07 Publication of NO310027B1 publication Critical patent/NO310027B1/no

Links

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WROMPOXWARCANT-UHFFFAOYSA-N tfa trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F.OC(=O)C(F)(F)F WROMPOXWARCANT-UHFFFAOYSA-N 0.000 description 1
210000002303 tibia Anatomy 0.000 description 1
ITMCEJHCFYSIIV-UHFFFAOYSA-N triflic acid Chemical compound OS(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-N 0.000 description 1
230000007306 turnover Effects 0.000 description 1
231100000397 ulcer Toxicity 0.000 description 1
230000002408 ulcerprotective effect Effects 0.000 description 1
238000002211 ultraviolet spectrum Methods 0.000 description 1
229960005486 vaccine Drugs 0.000 description 1
239000004474 valine Substances 0.000 description 1
125000002987 valine group Chemical group [H]N([H])C([H])(C(*)=O)C([H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Virology (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

NO940299A 1992-05-30 1994-01-28 Peptid med organbeskyttende aktivitet NO310027B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP92109145A EP0572688B1 (en)	1992-05-30	1992-05-30	Peptides with organo-protective activity, the process for preparing them and their use in therapy
PCT/EP1993/001352 WO1993024521A1 (en)	1992-05-30	1993-05-28	Bpc peptides, their preparation and use

Publications (3)

Publication Number	Publication Date
NO940299L NO940299L (no)	1994-01-28
NO940299D0 NO940299D0 (no)	1994-01-28
NO310027B1 true NO310027B1 (no)	2001-05-07

Family

ID=8209663

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO940299A NO310027B1 (no)	1992-05-30	1994-01-28	Peptid med organbeskyttende aktivitet

Country Status (22)

Country	Link
US (2)	US6211151B1 (bg)
EP (2)	EP0572688B1 (bg)
JP (1)	JP2783681B2 (bg)
KR (1)	KR0180256B1 (bg)
AT (2)	ATE152734T1 (bg)
AU (1)	AU4319693A (bg)
BG (1)	BG61477B1 (bg)
CA (1)	CA2114313C (bg)
CZ (1)	CZ284972B6 (bg)
DE (2)	DE69219590T2 (bg)
DK (2)	DK0572688T3 (bg)
ES (2)	ES2103854T3 (bg)
FI (1)	FI120454B (bg)
GR (2)	GR3024379T3 (bg)
HU (1)	HU224073B1 (bg)
NO (1)	NO310027B1 (bg)
PL (1)	PL176208B1 (bg)
RO (1)	RO112506B1 (bg)
RU (1)	RU2111214C1 (bg)
SK (1)	SK278507B6 (bg)
UA (1)	UA32523C2 (bg)
WO (1)	WO1993024521A1 (bg)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE152734T1 (de)	1992-05-30	1997-05-15	Sikiric Predrag	Bpc-peptide, deren herstellung und verwendung
RU2116311C1 (ru) *	1992-11-16	1998-07-27	Сикирич Предраг	Пептиды, обладающие органозащитной активностью, фармакологически активная композиция
SK159599A3 (en) *	1997-05-23	2000-11-07	Predrag Sikiric	New bpc peptide salts with organo-protective activity, the process for their preparation and their use in therapy
US8680059B2 (en)	1998-05-20	2014-03-25	Biotempt B.V.	Oligopeptide acetate and formulations thereof
US6844315B2 (en)	1998-05-20	2005-01-18	Erasmus Universiteit Rotterdam	Immunoregulator
US20030220258A1 (en)	2001-12-21	2003-11-27	Robbert Benner	Treatment of ischemic events
EP1138692A1 (en)	2000-03-29	2001-10-04	Erasmus Universiteit Rotterdam	Fragments of human chorionic gonadotropin (hcg) as immunoregulator
US7358330B2 (en)	2001-03-29	2008-04-15	Biotempt B.V.	Immunoregulatory compositions
USRE43279E1 (en)	2000-03-29	2012-03-27	Biotemp B.V.	Compositions capable of reducing elevated blood urea concentration
EP1300418A1 (en) *	2001-10-04	2003-04-09	Erasmus Universiteit Rotterdam	Gene regulation by oligopeptides
US7786084B2 (en) *	2001-12-21	2010-08-31	Biotempt B.V.	Treatment of burns
US7560433B2 (en)	2001-12-21	2009-07-14	Biotempt B.V.	Treatment of multiple sclerosis (MS)
US7517529B2 (en) *	2003-04-08	2009-04-14	Biotempt B.V.	Treatment of type I diabetes
RU2252779C1 (ru) *	2003-09-23	2005-05-27	Институт Молекулярной Генетики Российской Академии Наук (Имг Ран)	Способ профилактики и лечения язв желудочно-кишечного тракта
US20090227505A1 (en) *	2004-01-07	2009-09-10	Biotempt B.V.	Methods and uses for protein breakdown products
JP4846799B2 (ja)	2005-07-05	2011-12-28	バイオテンプトベー．フェー．	腫瘍の治療
CN101443080B (zh) *	2006-03-07	2015-01-14	比奥滕普特公司	肽在控制辐射损伤中的用途
EP1864692A1 (en) *	2006-06-07	2007-12-12	Biotempt B.V.	Use of peptides for the control of radiation injury
PT2120991E (pt) *	2007-02-12	2014-05-02	Biotempt Bv	Tratamento d a hemorragia traumática com oligopéptidos curtos
SI24318A (sl)	2013-03-13	2014-09-30	Diagen D.O.O.	Nove stabilne soli pentadekapeptida, postopek za njihovo pripravo, njihova uporaba za izdelavo farmacevtskih pripravkov in njihova uporaba v terapiji
CN113683663A (zh) *	2021-09-16	2021-11-23	杭州信海医药科技有限公司	一种机体保护多肽粗品的纯化方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8717300D0 (en) *	1987-07-22	1987-08-26	Nat Res Dev	Cyclosporins
CA1337781C (en) *	1987-08-21	1995-12-19	Takanori Nakamura	Polypeptide from horseshoe crab exhibiting affinity for lipopolysaccharide and method of preparation
YU176089A (sh) *	1989-09-12	1992-09-07	Sikirić, Predrag	Postupak za pripremu supstancije bpc i supstancija bpc
ATE152734T1 (de)	1992-05-30	1997-05-15	Sikiric Predrag	Bpc-peptide, deren herstellung und verwendung

1992
- 1992-05-30 AT AT92109145T patent/ATE152734T1/de active
- 1992-05-30 DK DK92109145.0T patent/DK0572688T3/da active
- 1992-05-30 EP EP92109145A patent/EP0572688B1/en not_active Expired - Lifetime
- 1992-05-30 DE DE69219590T patent/DE69219590T2/de not_active Expired - Lifetime
- 1992-05-30 ES ES92109145T patent/ES2103854T3/es not_active Expired - Lifetime
1993
- 1993-05-28 JP JP6500207A patent/JP2783681B2/ja not_active Expired - Lifetime
- 1993-05-28 SK SK96-94A patent/SK278507B6/sk not_active IP Right Cessation
- 1993-05-28 EP EP93912825A patent/EP0601154B1/en not_active Expired - Lifetime
- 1993-05-28 RO RO94-00101A patent/RO112506B1/ro unknown
- 1993-05-28 DK DK93912825.2T patent/DK0601154T3/da active
- 1993-05-28 ES ES93912825T patent/ES2107033T3/es not_active Expired - Lifetime
- 1993-05-28 CA CA002114313A patent/CA2114313C/en not_active Expired - Lifetime
- 1993-05-28 CZ CZ94205A patent/CZ284972B6/cs not_active IP Right Cessation
- 1993-05-28 AU AU43196/93A patent/AU4319693A/en not_active Abandoned
- 1993-05-28 DE DE69312232T patent/DE69312232T2/de not_active Expired - Lifetime
- 1993-05-28 UA UA93003868A patent/UA32523C2/uk unknown
- 1993-05-28 US US08/185,883 patent/US6211151B1/en not_active Expired - Fee Related
- 1993-05-28 PL PL93302304A patent/PL176208B1/pl not_active IP Right Cessation
- 1993-05-28 WO PCT/EP1993/001352 patent/WO1993024521A1/en not_active Ceased
- 1993-05-28 HU HU9400252A patent/HU224073B1/hu not_active IP Right Cessation
- 1993-05-28 AT AT93912825T patent/ATE155485T1/de active
- 1993-05-28 RU RU94041224A patent/RU2111214C1/ru not_active IP Right Cessation
1994
- 1994-01-26 FI FI940375A patent/FI120454B/fi not_active IP Right Cessation
- 1994-01-27 KR KR1019940700258A patent/KR0180256B1/ko not_active Expired - Fee Related
- 1994-01-28 NO NO940299A patent/NO310027B1/no not_active IP Right Cessation
- 1994-01-28 BG BG98426A patent/BG61477B1/bg unknown
1997
- 1997-08-07 GR GR970402020T patent/GR3024379T3/el unknown
- 1997-10-01 GR GR970402552T patent/GR3024905T3/el unknown
1998
- 1998-12-02 US US09/203,921 patent/US6268346B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2114313C (en)	2003-01-14
AU4319693A (en)	1993-12-30
ES2107033T3 (es)	1997-11-16
DE69219590D1 (de)	1997-06-12
CA2114313A1 (en)	1993-12-09
FI940375A0 (fi)	1994-01-26
DE69219590T2 (de)	1997-11-27
NO940299L (no)	1994-01-28
US6268346B1 (en)	2001-07-31
US6211151B1 (en)	2001-04-03
DE69312232T2 (de)	1998-01-29
HK1001004A1 (en)	1998-05-15
PL176208B1 (pl)	1999-04-30
DK0572688T3 (da)	1997-12-01
SK278507B6 (en)	1997-08-06
EP0601154A1 (en)	1994-06-15
EP0572688A1 (en)	1993-12-08
ATE155485T1 (de)	1997-08-15
FI120454B (fi)	2009-10-30
JP2783681B2 (ja)	1998-08-06
BG98426A (bg)	1995-02-28
ES2103854T3 (es)	1997-10-01
RU2111214C1 (ru)	1998-05-20
HU9400252D0 (en)	1994-05-30
ATE152734T1 (de)	1997-05-15
RO112506B1 (ro)	1997-10-30
SK9694A3 (en)	1994-08-10
BG61477B1 (en)	1997-09-30
FI940375L (fi)	1994-01-26
PL302304A1 (en)	1994-07-25
GR3024905T3 (en)	1998-01-30
DK0601154T3 (da)	1998-02-23
NO940299D0 (no)	1994-01-28
EP0572688B1 (en)	1997-05-07
WO1993024521A1 (en)	1993-12-09
JPH06509588A (ja)	1994-10-27
EP0601154B1 (en)	1997-07-16
KR0180256B1 (en)	1999-04-01
HU224073B1 (hu)	2005-05-30
GR3024379T3 (en)	1997-11-28
HUT66309A (en)	1994-11-28
CZ20594A3 (en)	1994-12-15
CZ284972B6 (cs)	1999-04-14
DE69312232D1 (de)	1997-08-21
UA32523C2 (uk)	2001-02-15

Legal Events

Date	Code	Title	Description
2012-12-27	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
US6211151B1 (en)	2001-04-03	Peptides with organo-protective activity, a process for preparation thereof and their use in therapy
KR100493830B1 (ko)	2006-04-21	친지성부및혈관작용성장펩티드(vip)의프래그먼트의콘쥬게이트
AU638468B2 (en)	1993-07-01	Hemoregulatory peptides
HK1001004B (en)	1998-05-15	Bpc peptides, their preparation and use
DE69316974T2 (de)	1998-07-16	Bpc-peptide, deren herstellung und therapeutischen verwendung
AU694701B2 (en)	1998-07-23	Peptides with organo-protective activity, their preparation and use
AU678917B2 (en)	1997-06-12	Peptides with organo-protective activity, their preparation and use
IE903420A1 (en)	1991-04-10	Novel CNS-active hexapeptides with an antiamnesic effect
HK1004554B (en)	1998-11-27	Hemoregulatory peptides