NO311806B1 - Forbindelser tilhörende amidiniumfamilien, farmasöytiske preparater inneholdende disse samt anvendelse derav - Google Patents

Forbindelser tilhörende amidiniumfamilien, farmasöytiske preparater inneholdende disse samt anvendelse derav Download PDF

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Publication number
NO311806B1
NO311806B1 NO19983691A NO983691A NO311806B1 NO 311806 B1 NO311806 B1 NO 311806B1 NO 19983691 A NO19983691 A NO 19983691A NO 983691 A NO983691 A NO 983691A NO 311806 B1 NO311806 B1 NO 311806B1
Authority
NO
Norway
Prior art keywords
nucleic acid
pharmaceutical preparation
preparation according
transfection
cells
Prior art date
Application number
NO19983691A
Other languages
English (en)
Norwegian (no)
Other versions
NO983691D0 (no
NO983691L (no
Inventor
Jean-Marie Lehn
Pierre Lehn
Jean-Pierre Vigneron
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26232562&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO311806(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR9602604A external-priority patent/FR2745569B1/fr
Priority claimed from FR9609557A external-priority patent/FR2751972B1/fr
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Publication of NO983691D0 publication Critical patent/NO983691D0/no
Publication of NO983691L publication Critical patent/NO983691L/no
Publication of NO311806B1 publication Critical patent/NO311806B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO19983691A 1996-03-01 1998-08-12 Forbindelser tilhörende amidiniumfamilien, farmasöytiske preparater inneholdende disse samt anvendelse derav NO311806B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9602604A FR2745569B1 (fr) 1996-03-01 1996-03-01 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications
FR9609557A FR2751972B1 (fr) 1996-07-30 1996-07-30 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications
PCT/FR1997/000364 WO1997031935A1 (fr) 1996-03-01 1997-02-28 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications

Publications (3)

Publication Number Publication Date
NO983691D0 NO983691D0 (no) 1998-08-12
NO983691L NO983691L (no) 1998-08-12
NO311806B1 true NO311806B1 (no) 2002-01-28

Family

ID=26232562

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19983691A NO311806B1 (no) 1996-03-01 1998-08-12 Forbindelser tilhörende amidiniumfamilien, farmasöytiske preparater inneholdende disse samt anvendelse derav

Country Status (18)

Country Link
US (2) US6143729A (de)
EP (1) EP0888379B1 (de)
JP (1) JP4271260B2 (de)
KR (1) KR19990087372A (de)
AT (1) ATE198599T1 (de)
AU (1) AU723998B2 (de)
BR (1) BRPI9707889B8 (de)
CZ (1) CZ295225B6 (de)
DE (1) DE69703878T2 (de)
DK (1) DK0888379T3 (de)
ES (1) ES2154453T3 (de)
GR (1) GR3035205T3 (de)
HU (1) HU228072B1 (de)
IL (1) IL125926A (de)
NO (1) NO311806B1 (de)
PT (1) PT888379E (de)
SK (1) SK283575B6 (de)
WO (1) WO1997031935A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884430B1 (en) 1997-02-10 2005-04-26 Aventis Pharma S.A. Formulation of stabilized cationic transfection agent(s) /nucleic acid particles
FR2763943B1 (fr) * 1997-05-28 1999-07-09 Rhone Poulenc Rorer Sa Composes, leur preparation et leur utilisation pour le transfert d'acides nucleiques dans les cellules
JP2002513543A (ja) * 1998-04-02 2002-05-14 アバンテイス・フアルマ・エス・アー 新規核酸移入剤とそれらを含む組成物及びそれらの使用
FR2777017B1 (fr) * 1998-04-02 2002-08-23 Rhone Poulenc Rorer Sa Nouveaux agents de transfert d'acides nucleiques, compositions les contenant et leurs applications
DE10109898A1 (de) * 2001-02-21 2002-09-05 Novosom Gmbh Lipide mit veränderlicher Ladung
FR2824557B1 (fr) * 2001-05-14 2003-08-29 Aventis Pharma Sa Derives lipidiques de polythiouree
AU2002257904B2 (en) * 2001-05-14 2007-12-06 Gencell S.A. Polythiourea lipid derivatives
FR2829136B1 (fr) * 2001-08-29 2006-11-17 Aventis Pharma Sa Derives lipidiques d'aminoglycosides
AU2003205545A1 (en) 2002-01-17 2003-07-30 York Refrigeration Aps Submerged evaporator with integrated heat exchanger
WO2006118283A1 (ja) * 2005-04-28 2006-11-09 Nippon Soda Co., Ltd. 新規なグアニジン化合物、製造方法及びそれらを含有する殺菌性組成物
CA2665403C (en) * 2006-10-04 2015-06-23 Institut National De La Sante Et De La Recherche Medicale (Inserm) Compositions comprising a sirna and lipidic 4,5-disubstituted 2-deoxystreptamine ring aminoglycoside derivatives and uses thereof
EP2350296A4 (de) * 2008-11-17 2013-04-03 Enzon Pharmaceuticals Inc Verzweigte kationische lipide für system zur zuführung von nukleinsäuren

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283185A (en) * 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
EP0730405A4 (de) * 1993-11-24 1997-02-19 Megabios Corp Amphiphile guanidin-derivate
US5777153A (en) * 1994-07-08 1998-07-07 Gilead Sciences, Inc. Cationic lipids
US6071890A (en) * 1994-12-09 2000-06-06 Genzyme Corporation Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
US5811406A (en) * 1995-06-07 1998-09-22 Regents Of The University Of California Dry powder formulations of polynucleotide complexes

Also Published As

Publication number Publication date
IL125926A (en) 2004-09-27
BR9707889B1 (pt) 2010-03-23
DE69703878T2 (de) 2001-04-26
DK0888379T3 (da) 2001-01-29
AU1930497A (en) 1997-09-16
KR19990087372A (ko) 1999-12-27
PT888379E (pt) 2001-05-31
JP2000506136A (ja) 2000-05-23
GR3035205T3 (en) 2001-04-30
US6316422B1 (en) 2001-11-13
DE69703878D1 (de) 2001-02-15
NO983691D0 (no) 1998-08-12
EP0888379B1 (de) 2001-01-10
JP4271260B2 (ja) 2009-06-03
EP0888379A1 (de) 1999-01-07
BRPI9707889B8 (pt) 2016-11-08
HU228072B1 (en) 2012-09-28
BR9707889A (pt) 2000-01-04
AU723998B2 (en) 2000-09-07
SK118298A3 (en) 1999-02-11
NO983691L (no) 1998-08-12
HUP9902465A1 (hu) 1999-12-28
KR100452062B1 (de) 2005-04-08
SK283575B6 (sk) 2003-09-11
ES2154453T3 (es) 2001-04-01
IL125926A0 (en) 1999-04-11
CZ277298A3 (cs) 1998-12-16
CZ295225B6 (cs) 2005-06-15
HUP9902465A3 (en) 2009-10-28
ATE198599T1 (de) 2001-01-15
WO1997031935A1 (fr) 1997-09-04
US6143729A (en) 2000-11-07

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