NO314357B1 - Fytosterol og/eller fytosterolderivater - Google Patents

Fytosterol og/eller fytosterolderivater Download PDF

Info

Publication number: NO314357B1
Authority: NO; Norway
Prior art keywords: esters; mixture; phytosterol; phytosterols; beta
Prior art date: 1998-11-26

Application number

NO19995784A

Other languages

English (en)

Norwegian (no)

Other versions

NO995784L (no

NO995784D0 (no

Inventor

David Carl Burdick

Gerard Moine

Daniel Raederstorff

Peter Weber

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-26

Filing date

1999-11-25

Publication date

2003-03-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26149828&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO314357(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-11-25 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1999-11-25 Publication of NO995784D0 publication Critical patent/NO995784D0/no

2000-05-29 Publication of NO995784L publication Critical patent/NO995784L/no

2003-03-10 Publication of NO314357B1 publication Critical patent/NO314357B1/no

Links

239000000203 mixture Substances 0.000 claims description 62
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229940068065 phytosterols Drugs 0.000 claims description 34
MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims description 29
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LGJMUZUPVCAVPU-HRJGVYIJSA-N stigmastanol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]2(C)CC1 LGJMUZUPVCAVPU-HRJGVYIJSA-N 0.000 claims description 21
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238000011160 research Methods 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
NRHMKIHPTBHXPF-TUJRSCDTSA-M sodium cholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 NRHMKIHPTBHXPF-TUJRSCDTSA-M 0.000 description 1
238000007619 statistical method Methods 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
229930003802 tocotrienol Natural products 0.000 description 1
239000011731 tocotrienol Substances 0.000 description 1
235000019148 tocotrienols Nutrition 0.000 description 1
125000005457 triglyceride group Chemical group 0.000 description 1
235000021122 unsaturated fatty acids Nutrition 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
235000019195 vitamin supplement Nutrition 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings or cooking oils characterised by ingredients other than fatty acid triglycerides
- A23D9/013—Other fatty acid esters, e.g. phosphatides
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
- A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Hematology (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Botany (AREA)
Food Science & Technology (AREA)
Polymers & Plastics (AREA)
Obesity (AREA)
Nutrition Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Epidemiology (AREA)
Mycology (AREA)
Child & Adolescent Psychology (AREA)
Wood Science & Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Edible Oils And Fats (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO19995784A 1998-11-26 1999-11-25 Fytosterol og/eller fytosterolderivater NO314357B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98122412		1998-11-26
EP99119337		1999-09-29

Publications (3)

Publication Number	Publication Date
NO995784D0 NO995784D0 (no)	1999-11-25
NO995784L NO995784L (no)	2000-05-29
NO314357B1 true NO314357B1 (no)	2003-03-10

Family

ID=26149828

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19995784A NO314357B1 (no)	1998-11-26	1999-11-25	Fytosterol og/eller fytosterolderivater

Country Status (17)

Country	Link
US (4)	US20020160990A1 (de)
EP (1)	EP1004594B1 (de)
JP (1)	JP2000159792A (de)
KR (1)	KR100678831B1 (de)
CN (2)	CN1135234C (de)
AR (1)	AR025141A1 (de)
AT (1)	ATE246704T1 (de)
AU (1)	AU762539B2 (de)
BR (1)	BR9905398A (de)
CA (1)	CA2290331C (de)
DE (1)	DE69910152T2 (de)
DK (1)	DK1004594T3 (de)
ES (1)	ES2204052T3 (de)
ID (1)	ID24148A (de)
MX (1)	MX215122B (de)
NO (1)	NO314357B1 (de)
NZ (1)	NZ501169A (de)

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EP1155104A2 (de) *	1999-02-10	2001-11-21	Eastman Chemical Company	Maisfasern für die herstellung von wertvollen verbindungen und materialien
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CA2382262C (en) *	1999-08-30	2004-12-07	Ocean Nutrition Canada Ltd.	A nutritional supplement for lowering serum triglyceride and cholesterol levels
US6838098B2 (en)	2000-09-07	2005-01-04	Cadbury Adams Usa, Llc	Continuous formation of center filled gum
SE523094C2 (sv) *	2001-01-11	2004-03-30	Karlshamns Ab	Förfarande för framställning av en fettkomposition som innehåller sterolestrar, fria steroler och glycerider, fettkomposition framställd genom förfarandet samt fettkompositionens användning
US6623266B2 (en)	2001-01-19	2003-09-23	Cadbury Adams Usa Llc	Apparatus for making a center-filled gum lollipop with hard candy shell
KR20020081834A (ko) *	2001-04-20	2002-10-30	주식회사 유엘바이오텍	식물성 스테롤의 유도체를 이용한 혈중 콜레스테롤저하제의 제조방법 및 이에 의해 제조된 혈중 콜레스테롤저하제
KR100440613B1 (ko) *	2001-04-20	2004-08-16	주식회사 유엘바이오텍	식물성스테롤과 생 플라보노이드의 결합체를 이용한 혈중콜레스테롤 저하제의 제조방법과 이에 의해 제조한 혈중콜레스테롤 저하제
EP1275309A1 (de) *	2001-07-13	2003-01-15	Ikeda Food Research Co. Ltd.	Sterol Fettsäure Ester Zusammensetzung und diese enthaltende Lebensmittel
WO2003009854A1 (en) *	2001-07-20	2003-02-06	Lonza Ag	Lipid lowering composition comprising carnitine and phytosterol
FI20012553A0 (fi) *	2001-12-21	2001-12-21	Raisio Benecol Oy	Syötävät koostumukset
CA2481384A1 (en) *	2002-04-10	2003-10-23	Cargill, Incorporated	Aqueous dispersible steryl ester compositions
US8821915B2 (en)	2002-08-09	2014-09-02	Veroscience, Llc	Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
US20040081678A1 (en) *	2002-08-09	2004-04-29	Anthony Cincotta	Therapeutic process for the treatment of obesity and associated metabolic disorders
EP1466597A1 (de) *	2003-04-07	2004-10-13	Clinigenetics	Verwendung von dha-Esteren in der Behandlung kardiovasculärer Krankheiten
WO2004091603A1 (fr) *	2003-04-07	2004-10-28	Clinigenetics	Utilisation d’un ester de dha pour le traitement des malades cardiovasculaires
KR101054913B1 (ko) *	2003-12-31	2011-08-05	주식회사 삼양제넥스	식물스테롤, 헤스페리딘 및 루틴을 포함하는 고지혈증,동맥경화증 및 간질환 예방 및 치료용 조성물
US8158184B2 (en) *	2004-03-08	2012-04-17	Bunge Oils, Inc.	Structured lipid containing compositions and methods with health and nutrition promoting characteristics
US7641926B2 (en)	2004-08-25	2010-01-05	Cadbury Adams Usa, Llc	Liquid-filled chewing gum composition
US7727565B2 (en)	2004-08-25	2010-06-01	Cadbury Adams Usa Llc	Liquid-filled chewing gum composition
US7678399B2 (en)	2005-12-05	2010-03-16	Bunge Oils, Inc.	Phytosterol containing deep-fried foods and methods with health promoting characteristics
BRPI0710844A2 (pt)	2006-04-05	2011-08-23	Cadbury Adams Usa Llc	composição de confeito , método e kit de remineralizar e de conferir resistência a ácido a superficie dos dentes de um mamìfero
ES2619161T3 (es)	2006-04-05	2017-06-23	Intercontinental Great Brands Llc	Complejo de fosfato de calcio y sales en sistemas de suministro oral
US20070298079A1 (en) *	2006-06-26	2007-12-27	Tropicana Products, Inc.	Food fortified with omega-3 fatty acids
ES2765625T3 (es)	2006-06-29	2020-06-10	Intercontinental Great Brands Llc	Cortador de cadena mejorado para conformar de forma continua piezas de chicle con relleno central
GB0905367D0 (en) *	2009-03-27	2009-05-13	Danisco	Method
US9352025B2 (en)	2009-06-05	2016-05-31	Veroscience Llc	Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
CN101919537B (zh) *	2010-09-09	2012-08-08	浙江大学	植物甾烷醇酯和共轭亚油酸酯在功能性肉制品中的应用
FI123374B (fi) *	2011-03-25	2013-03-15	Ravintoraisio Oy	Uusi syötävä koostumus
CN102318686B (zh) *	2011-06-01	2012-12-19	黑龙江省大豆技术开发研究中心	一种制备含有植物甾醇酯的功能性保健油脂的方法
CN102603846A (zh) *	2012-02-03	2012-07-25	江南大学	一种离子液体中植物甾醇酯的制备方法
CN103242407A (zh) *	2013-05-15	2013-08-14	张雅茹	含多不饱和脂肪酰基的磷脂酰甾醇和/或磷脂酰甾烷醇及制备方法和应用
IL237290A0 (en) *	2015-02-17	2015-06-30	Enzymotec Ltd	Oil mixtures for use in formulas
US10188133B2 (en) *	2015-04-23	2019-01-29	Basf Se	Gel capsule containing sterol and solubilising agent
CN109200061A (zh) *	2017-06-29	2019-01-15	四川国为制药有限公司	一种高纯度鱼油与植物甾醇酯的降血脂组合物
WO2020259493A1 (en) *	2019-06-24	2020-12-30	Basf Se	Compositions and methods for the prevention or treatment, or dietary management of nafld
CN113197310A (zh) *	2021-05-21	2021-08-03	江苏越红生物科技有限公司	一种富含油酸的植物甾醇酯的制备方法
CN120860036B (zh) *	2025-09-29	2026-01-27	湖南农业大学	一种植物甾醇和植物甾醇酯复合剂及其应用

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USRE30910E (en) *	1971-03-19	1982-04-20	Intellectual Property Development Corporation	Reducing cholesterol levels
US4588717A (en) *	1984-06-13	1986-05-13	David C. Mitchell Medical Research Institute	Compounds and vitamin supplements and methods for making same
US5502045A (en) *	1991-05-03	1996-03-26	Raision Tehtaat Oy Ab	Use of a stanol fatty acid ester for reducing serum cholesterol level
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FI107015B (fi) *	1996-08-09	2001-05-31	Raisio Benecol Oy	Kasvistanolirasvahappoestereiden seos ja sen käyttö sekä elintarvike
CA2346881A1 (en) *	1998-07-20	2000-02-03	Egon Novak	Compositions comprising phytosterol, phytostanol or mixtures of both and omega-3 fatty acids or derivatives thereof and use of the composition in treating or preventing cardiovascular disease and other disorders
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1999
- 1999-11-18 NZ NZ501169A patent/NZ501169A/en not_active IP Right Cessation
- 1999-11-18 ID IDP991068A patent/ID24148A/id unknown
- 1999-11-19 DK DK99122978T patent/DK1004594T3/da active
- 1999-11-19 CA CA002290331A patent/CA2290331C/en not_active Expired - Fee Related
- 1999-11-19 ES ES99122978T patent/ES2204052T3/es not_active Expired - Lifetime
- 1999-11-19 DE DE69910152T patent/DE69910152T2/de not_active Revoked
- 1999-11-19 MX MX9910678A patent/MX215122B/es not_active IP Right Cessation
- 1999-11-19 AT AT99122978T patent/ATE246704T1/de not_active IP Right Cessation
- 1999-11-19 EP EP99122978A patent/EP1004594B1/de not_active Revoked
- 1999-11-22 JP JP11330770A patent/JP2000159792A/ja not_active Withdrawn
- 1999-11-23 KR KR1019990052052A patent/KR100678831B1/ko not_active Expired - Fee Related
- 1999-11-23 US US09/448,356 patent/US20020160990A1/en not_active Abandoned
- 1999-11-24 AR ARP990105983A patent/AR025141A1/es unknown
- 1999-11-25 AU AU60655/99A patent/AU762539B2/en not_active Ceased
- 1999-11-25 NO NO19995784A patent/NO314357B1/no not_active IP Right Cessation
- 1999-11-25 BR BR9905398-5A patent/BR9905398A/pt not_active Application Discontinuation
- 1999-11-26 CN CNB99124382XA patent/CN1135234C/zh not_active Expired - Fee Related
- 1999-11-26 CN CNB2003101154954A patent/CN1272011C/zh not_active Expired - Fee Related
2001
- 2001-11-20 US US09/989,554 patent/US20020055493A1/en not_active Abandoned
2005
- 2005-07-25 US US11/189,667 patent/US20050261259A1/en not_active Abandoned
2006
- 2006-12-04 US US11/634,032 patent/US20070078115A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN1272011C (zh)	2006-08-30
NO995784L (no)	2000-05-29
NZ501169A (en)	2001-05-25
ID24148A (id)	2000-07-13
EP1004594A1 (de)	2000-05-31
BR9905398A (pt)	2000-08-08
AU762539B2 (en)	2003-06-26
AR025141A1 (es)	2002-11-13
ES2204052T3 (es)	2004-04-16
CN1494909A (zh)	2004-05-12
CN1256277A (zh)	2000-06-14
DE69910152D1 (de)	2003-09-11
US20020055493A1 (en)	2002-05-09
DK1004594T3 (da)	2003-11-17
JP2000159792A (ja)	2000-06-13
CN1135234C (zh)	2004-01-21
DE69910152T2 (de)	2004-06-09
CA2290331A1 (en)	2000-05-26
MX215122B (en)	2003-07-08
MX9910678A (en)	2000-04-30
ATE246704T1 (de)	2003-08-15
KR100678831B1 (ko)	2007-02-05
US20020160990A1 (en)	2002-10-31
NO995784D0 (no)	1999-11-25
US20070078115A1 (en)	2007-04-05
US20050261259A1 (en)	2005-11-24
CA2290331C (en)	2008-01-15
EP1004594B1 (de)	2003-08-06
AU6065599A (en)	2000-06-01
KR20000035619A (ko)	2000-06-26

Legal Events

Date	Code	Title	Description
2011-06-27	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
NO314357B1 (no)	2003-03-10	Fytosterol og/eller fytosterolderivater
MXPA99010678A (en)	2000-12-06	Phytosterol and / or phytostate derivatives
AU758747B2 (en)	2003-03-27	Phytosterol compositions
CN100408592C (zh)	2008-08-06	油中植物甾醇酯的分馏
JP2000513730A (ja)	2000-10-17	スタノール組成物及びその用途
AU782264B2 (en)	2005-07-14	Edible fat blends
US20070218183A1 (en)	2007-09-20	Oil composition of conjugated linoleic acid
Jones et al.	1998	Comparable efficacy of hydrogenated versus nonhydrogenated plant sterol esters on circulating cholesterol levels in humans
US20020107232A1 (en)	2002-08-08	Methods for producing sterol ester-rich compositions
EP1370148A1 (de)	2003-12-17	Cholesterinspiegelsenkendes speiseöl
JP2002322052A (ja)	2002-11-08	小腸上皮中の脂質代謝改善剤
US20100179113A1 (en)	2010-07-15	Stanol composition and the use thereof
JP4018863B2 (ja)	2007-12-05	油脂組成物
AU2001236584A1 (en)	2002-08-12	Anticholesterolemic edible oil