NO319940B1 - Anvendelse av vismutsalter ved fremstilling av sammensetning - Google Patents
Anvendelse av vismutsalter ved fremstilling av sammensetning Download PDFInfo
- Publication number
- NO319940B1 NO319940B1 NO19982632A NO982632A NO319940B1 NO 319940 B1 NO319940 B1 NO 319940B1 NO 19982632 A NO19982632 A NO 19982632A NO 982632 A NO982632 A NO 982632A NO 319940 B1 NO319940 B1 NO 319940B1
- Authority
- NO
- Norway
- Prior art keywords
- bismuth
- algae
- use according
- pharmaceutically acceptable
- cyanobacteria
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 21
- 150000001621 bismuth Chemical class 0.000 title claims description 15
- 238000002360 preparation method Methods 0.000 title claims description 3
- 229910052797 bismuth Inorganic materials 0.000 claims abstract description 25
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 claims abstract description 25
- 241000195493 Cryptophyta Species 0.000 claims abstract description 24
- 241000192700 Cyanobacteria Species 0.000 claims abstract description 23
- 208000018522 Gastrointestinal disease Diseases 0.000 claims abstract description 18
- 230000001404 mediated effect Effects 0.000 claims abstract description 11
- 208000010643 digestive system disease Diseases 0.000 claims abstract description 9
- 208000018685 gastrointestinal system disease Diseases 0.000 claims abstract description 9
- 230000002265 prevention Effects 0.000 claims abstract description 8
- 241000195649 Chlorella <Chlorellales> Species 0.000 claims description 5
- ZREIPSZUJIFJNP-UHFFFAOYSA-K bismuth subsalicylate Chemical compound C1=CC=C2O[Bi](O)OC(=O)C2=C1 ZREIPSZUJIFJNP-UHFFFAOYSA-K 0.000 claims description 5
- 229960000782 bismuth subsalicylate Drugs 0.000 claims description 5
- 241000180279 Chlorococcum Species 0.000 claims description 4
- 229960004645 bismuth subcitrate Drugs 0.000 claims description 4
- JAONZGLTYYUPCT-UHFFFAOYSA-K bismuth subgallate Chemical compound OC(=O)C1=CC(O)=C2O[Bi](O)OC2=C1 JAONZGLTYYUPCT-UHFFFAOYSA-K 0.000 claims description 4
- 229960000199 bismuth subgallate Drugs 0.000 claims description 4
- ZQUAVILLCXTKTF-UHFFFAOYSA-H bismuth;tripotassium;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [K+].[K+].[K+].[Bi+3].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O ZQUAVILLCXTKTF-UHFFFAOYSA-H 0.000 claims description 4
- KKMOSYLWYLMHAL-UHFFFAOYSA-N 2-bromo-6-nitroaniline Chemical compound NC1=C(Br)C=CC=C1[N+]([O-])=O KKMOSYLWYLMHAL-UHFFFAOYSA-N 0.000 claims description 3
- 229940104825 bismuth aluminate Drugs 0.000 claims description 3
- SULICOHAQXOMED-YDXPQRMKSA-H dibismuth;(2r,3r)-2,3-dihydroxybutanedioate Chemical compound [Bi+3].[Bi+3].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O.[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O.[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O SULICOHAQXOMED-YDXPQRMKSA-H 0.000 claims description 3
- PDSAKIXGSONUIX-UHFFFAOYSA-N hexaaluminum;dibismuth;oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[Bi+3].[Bi+3] PDSAKIXGSONUIX-UHFFFAOYSA-N 0.000 claims description 3
- 229910000014 Bismuth subcarbonate Inorganic materials 0.000 claims description 2
- MGLUJXPJRXTKJM-UHFFFAOYSA-L bismuth subcarbonate Chemical compound O=[Bi]OC(=O)O[Bi]=O MGLUJXPJRXTKJM-UHFFFAOYSA-L 0.000 claims description 2
- 229940036358 bismuth subcarbonate Drugs 0.000 claims description 2
- 241000192542 Anabaena Species 0.000 claims 1
- 244000085413 Aphanizomenon flos aquae Species 0.000 claims 1
- 235000013781 Aphanizomenon flos aquae Nutrition 0.000 claims 1
- 241000192701 Microcystis Species 0.000 claims 1
- 229940054349 aphanizomenon flos-aquae Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 4
- 241001465754 Metazoa Species 0.000 abstract description 3
- 208000015181 infectious disease Diseases 0.000 description 8
- 241000195628 Chlorophyta Species 0.000 description 7
- 206010012735 Diarrhoea Diseases 0.000 description 7
- 241000206751 Chrysophyceae Species 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 241000199914 Dinophyceae Species 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 241000195623 Euglenida Species 0.000 description 3
- 206010061598 Immunodeficiency Diseases 0.000 description 3
- 241000199919 Phaeophyceae Species 0.000 description 3
- 241000206572 Rhodophyta Species 0.000 description 3
- 208000030507 AIDS Diseases 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 2
- 241000206761 Bacillariophyta Species 0.000 description 2
- HWSISDHAHRVNMT-UHFFFAOYSA-N Bismuth subnitrate Chemical compound O[NH+]([O-])O[Bi](O[N+]([O-])=O)O[N+]([O-])=O HWSISDHAHRVNMT-UHFFFAOYSA-N 0.000 description 2
- 241000391095 Dinobryon Species 0.000 description 2
- 241000192710 Microcystis aeruginosa Species 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 241000199481 Synura Species 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 201000009840 acute diarrhea Diseases 0.000 description 2
- 239000004599 antimicrobial Substances 0.000 description 2
- 229960001482 bismuth subnitrate Drugs 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000002550 fecal effect Effects 0.000 description 2
- 210000003097 mucus Anatomy 0.000 description 2
- 230000000243 photosynthetic effect Effects 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 241000192660 Aphanizomenon Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241001442195 Bangia Species 0.000 description 1
- 241001474374 Blennius Species 0.000 description 1
- 241001488115 Catenella Species 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241001464430 Cyanobacterium Species 0.000 description 1
- 208000005156 Dehydration Diseases 0.000 description 1
- 241000218614 Dinophysis acuminata Species 0.000 description 1
- 241000507812 Dinophysis norvegica Species 0.000 description 1
- 241000192534 Dolichospermum flos-aquae Species 0.000 description 1
- 206010014418 Electrolyte imbalance Diseases 0.000 description 1
- 208000005577 Gastroenteritis Diseases 0.000 description 1
- 241000200139 Gonyaulax Species 0.000 description 1
- 240000008415 Lactuca sativa Species 0.000 description 1
- 241000237852 Mollusca Species 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 241000180701 Nitzschia <flatworm> Species 0.000 description 1
- 241001472321 Phacus pleuronectes Species 0.000 description 1
- 241000206609 Porphyra Species 0.000 description 1
- 241001503543 Pseudo-nitzschia pungens Species 0.000 description 1
- 241000199893 Pylaiella littoralis Species 0.000 description 1
- 241001360436 Trachelomonas armata Species 0.000 description 1
- 241000192117 Trichodesmium erythraeum Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 241000206764 Xanthophyceae Species 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- NNBFNNNWANBMTI-UHFFFAOYSA-M brilliant green Chemical compound OS([O-])(=O)=O.C1=CC(N(CC)CC)=CC=C1C(C=1C=CC=CC=1)=C1C=CC(=[N+](CC)CC)C=C1 NNBFNNNWANBMTI-UHFFFAOYSA-M 0.000 description 1
- 206010009887 colitis Diseases 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000000741 diarrhetic effect Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 206010016766 flatulence Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000013505 freshwater Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000003750 lower gastrointestinal tract Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 229940101070 pepto-bismol Drugs 0.000 description 1
- 230000029553 photosynthesis Effects 0.000 description 1
- 238000010672 photosynthesis Methods 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 235000012045 salad Nutrition 0.000 description 1
- 235000014102 seafood Nutrition 0.000 description 1
- 235000015170 shellfish Nutrition 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- SPRBJFWIUVWXBT-UHFFFAOYSA-K tripotassium 2-hydroxypropane-1,2,3-tricarboxylate 2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [K+].[K+].[K+].OC(=O)CC(O)(C(O)=O)CC(O)=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O SPRBJFWIUVWXBT-UHFFFAOYSA-K 0.000 description 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 208000016261 weight loss Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/245—Bismuth; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/569,028 US5702729A (en) | 1995-12-07 | 1995-12-07 | Methods for the prevention and treatment of gastrointestinal disorders caused or mediated by algae or cyanobacteria |
| PCT/US1996/018655 WO1997020568A1 (en) | 1995-12-07 | 1996-11-22 | Compositions, containing bismuth, for the prevention and treatment of gastrointestinal disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO982632D0 NO982632D0 (no) | 1998-06-08 |
| NO982632L NO982632L (no) | 1998-08-04 |
| NO319940B1 true NO319940B1 (no) | 2005-10-03 |
Family
ID=24273798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19982632A NO319940B1 (no) | 1995-12-07 | 1998-06-08 | Anvendelse av vismutsalter ved fremstilling av sammensetning |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5702729A (de) |
| EP (1) | EP0865287B1 (de) |
| AT (1) | ATE213637T1 (de) |
| BR (1) | BR9611927A (de) |
| CA (1) | CA2239433C (de) |
| CO (1) | CO4761072A1 (de) |
| DE (1) | DE69619542T2 (de) |
| DK (1) | DK0865287T3 (de) |
| ES (1) | ES2173334T3 (de) |
| IL (1) | IL124729A (de) |
| MX (1) | MX9804576A (de) |
| MY (1) | MY118760A (de) |
| NO (1) | NO319940B1 (de) |
| PE (1) | PE37398A1 (de) |
| PT (1) | PT865287E (de) |
| TR (1) | TR199801021T2 (de) |
| TW (1) | TW393316B (de) |
| WO (1) | WO1997020568A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101583656B (zh) | 2007-01-16 | 2012-09-05 | 巴斯夫欧洲公司 | 含有发泡热塑性弹性体和聚氨酯的混杂体系 |
| CN107129950B (zh) * | 2017-06-09 | 2020-10-30 | 复旦大学 | 一种用于净化生活污水的活性藻菌共同体和制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR962163A (de) * | 1950-06-02 | |||
| US4049817A (en) * | 1972-08-14 | 1977-09-20 | Sandoz Ltd. | Synergistic compositions |
| US4514421A (en) * | 1979-08-30 | 1985-04-30 | Herschler R J | Dietary and pharmaceutical uses of methylsulfonylmethane and compositions comprising it |
| EP0222834A4 (de) * | 1985-04-18 | 1989-10-04 | Borody Thomas J | Behandlung von nichtulcerativer dyspepsia mit wismutsalzen. |
| EP0206625B1 (de) * | 1985-06-13 | 1992-09-30 | Barry James Dr. Marshall | Zusammensetzungen zur Behandlung von Magen-Darmstörungen |
| US5256684A (en) * | 1985-06-13 | 1993-10-26 | The Procter & Gamble Company | Methods and compositions for the treatment of gastrointestinal disorders |
| DE3686362T2 (de) * | 1985-06-13 | 1993-02-11 | Marshall Barry James | Verfahren zur behandlung von magen-darmstoerungen. |
| JPS63174926A (ja) * | 1987-01-09 | 1988-07-19 | Nitto Kasei Kk | 家禽用抗コクシジウム剤 |
| US5196205A (en) * | 1987-10-12 | 1993-03-23 | Borody Thomas J | Method for treatment of gastro intestinal disorders |
| EP0375068A1 (de) * | 1988-12-23 | 1990-06-27 | Gist-Brocades N.V. | Mischungen von Bismuth-Verbindungen und Tetracyclinen |
| US5221664A (en) * | 1990-04-23 | 1993-06-22 | Magainin Pharmaaceuticals Inc. | Composition and treatment with biologically active peptides and toxic cations |
| ATE135227T1 (de) * | 1990-07-20 | 1996-03-15 | Slagel David | Produkte und verfahren zur behandlung des verdauungskanals |
| DE59309771D1 (de) * | 1993-05-11 | 1999-10-14 | Spirig Ag | Festes bismut- und amoxycillinhaltiges Arzneipräparat und seine Verwendung |
| CA2184361C (en) * | 1994-03-24 | 2000-12-05 | Francis Bernard Chapura | Solid dose forms containing bismuth |
| AUPM596894A0 (en) * | 1994-05-30 | 1994-06-23 | Hybrid Scientific Pty Ltd | Composition for treating gastrointestinal disorders - a combination of bismuth salts plus lactobacillus or bifidobacteria species bacteria for treating gastrointestinal disorders |
-
1995
- 1995-12-07 US US08/569,028 patent/US5702729A/en not_active Expired - Fee Related
-
1996
- 1996-11-22 WO PCT/US1996/018655 patent/WO1997020568A1/en not_active Ceased
- 1996-11-22 ES ES96940571T patent/ES2173334T3/es not_active Expired - Lifetime
- 1996-11-22 IL IL12472996A patent/IL124729A/xx not_active IP Right Cessation
- 1996-11-22 AT AT96940571T patent/ATE213637T1/de not_active IP Right Cessation
- 1996-11-22 CA CA002239433A patent/CA2239433C/en not_active Expired - Fee Related
- 1996-11-22 PT PT96940571T patent/PT865287E/pt unknown
- 1996-11-22 BR BR9611927A patent/BR9611927A/pt not_active Application Discontinuation
- 1996-11-22 EP EP96940571A patent/EP0865287B1/de not_active Expired - Lifetime
- 1996-11-22 DK DK96940571T patent/DK0865287T3/da active
- 1996-11-22 TR TR1998/01021T patent/TR199801021T2/xx unknown
- 1996-11-22 DE DE69619542T patent/DE69619542T2/de not_active Expired - Fee Related
- 1996-12-04 CO CO96063579A patent/CO4761072A1/es unknown
- 1996-12-07 MY MYPI96005152A patent/MY118760A/en unknown
- 1996-12-09 PE PE1996000888A patent/PE37398A1/es not_active Application Discontinuation
- 1996-12-26 TW TW085116049A patent/TW393316B/zh not_active IP Right Cessation
-
1998
- 1998-06-08 MX MX9804576A patent/MX9804576A/es unknown
- 1998-06-08 NO NO19982632A patent/NO319940B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL124729A0 (en) | 1999-01-26 |
| IL124729A (en) | 2003-01-12 |
| MY118760A (en) | 2005-01-31 |
| BR9611927A (pt) | 1999-03-30 |
| ATE213637T1 (de) | 2002-03-15 |
| WO1997020568A1 (en) | 1997-06-12 |
| EP0865287B1 (de) | 2002-02-27 |
| NO982632D0 (no) | 1998-06-08 |
| ES2173334T3 (es) | 2002-10-16 |
| US5702729A (en) | 1997-12-30 |
| TW393316B (en) | 2000-06-11 |
| NO982632L (no) | 1998-08-04 |
| EP0865287A1 (de) | 1998-09-23 |
| CA2239433A1 (en) | 1997-06-12 |
| DE69619542D1 (de) | 2002-04-04 |
| DK0865287T3 (da) | 2002-03-25 |
| MX9804576A (es) | 1998-10-31 |
| DE69619542T2 (de) | 2002-10-31 |
| CO4761072A1 (es) | 1999-04-27 |
| TR199801021T2 (xx) | 1998-09-21 |
| PE37398A1 (es) | 1998-08-10 |
| PT865287E (pt) | 2002-06-28 |
| CA2239433C (en) | 2003-04-22 |
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