NO321466B1 - Fremgangsmate for immunologisk pavisning av antistoffer rettet mot vevstransglutaminase (tTG), oralt farmasoytisk middel inneholdende tTG, samt anvendelse av tTG-inneholdende forbindelser. - Google Patents

Fremgangsmate for immunologisk pavisning av antistoffer rettet mot vevstransglutaminase (tTG), oralt farmasoytisk middel inneholdende tTG, samt anvendelse av tTG-inneholdende forbindelser. Download PDF

Info

Publication number: NO321466B1
Authority: NO; Norway
Prior art keywords: ttg; antibody; containing compounds; sprue; detection
Prior art date: 1996-07-18

Application number

NO19990190A

Other languages

English (en)

Norwegian (no)

Other versions

NO990190L (no

NO990190D0 (no

Inventor

Tobias Ehnis

Detlef Schuppan

Walburga Dieterich

Original Assignee

Detlef Schuppan

Walburga Dieterich

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-18

Filing date

1999-01-15

Publication date

2006-05-15

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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7801172&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO321466(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-01-15 Application filed by Detlef Schuppan, Walburga Dieterich filed Critical Detlef Schuppan

1999-01-15 Publication of NO990190D0 publication Critical patent/NO990190D0/no

1999-03-15 Publication of NO990190L publication Critical patent/NO990190L/no

2006-05-15 Publication of NO321466B1 publication Critical patent/NO321466B1/no

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Urology & Nephrology (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pathology (AREA)
General Physics & Mathematics (AREA)
Cell Biology (AREA)
Wood Science & Technology (AREA)
Rheumatology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Rehabilitation Therapy (AREA)
Gastroenterology & Hepatology (AREA)
General Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Toxicology (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)

NO19990190A 1996-07-18 1999-01-15 Fremgangsmate for immunologisk pavisning av antistoffer rettet mot vevstransglutaminase (tTG), oralt farmasoytisk middel inneholdende tTG, samt anvendelse av tTG-inneholdende forbindelser. NO321466B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19630557A DE19630557C2 (de)	1996-07-18	1996-07-18	Verfahren zum Nachweis von Antikörpern aus Körperflüssigkeiten durch eine Immunreaktion mit Gewebe-Transglutaminase (tTG) sowie die Verwendung von tTG in Diagnose und Therapie
PCT/EP1997/003740 WO1998003872A2 (de)	1996-07-18	1997-07-14	IMMUNOLOGISCHES NACHWEISVERFAHREN VON ANTIKÖRPERN, DIE GEGEN GEWEBE-TRANSGLUTAMINASE (tTG) GERICHTET SIND, VERWENDUNG VON tTG ZUR DIAGNOSE UND THERAPIEKONTROLLE SOWIE ORALES PHARMAZEUTISCHES MITTEL ENTHALTEND tTG

Publications (3)

Publication Number	Publication Date
NO990190D0 NO990190D0 (no)	1999-01-15
NO990190L NO990190L (no)	1999-03-15
NO321466B1 true NO321466B1 (no)	2006-05-15

Family

ID=7801172

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19990190A NO321466B1 (no)	1996-07-18	1999-01-15	Fremgangsmate for immunologisk pavisning av antistoffer rettet mot vevstransglutaminase (tTG), oralt farmasoytisk middel inneholdende tTG, samt anvendelse av tTG-inneholdende forbindelser.

Country Status (21)

Country	Link
US (2)	US6319726B1 (da)
EP (1)	EP0912898B1 (da)
CN (1)	CN1138146C (da)
AT (1)	ATE210296T1 (da)
AU (1)	AU718797B2 (da)
BR (1)	BR9710500B1 (da)
CA (1)	CA2260769C (da)
CZ (1)	CZ291662B6 (da)
DE (2)	DE19630557C2 (da)
DK (1)	DK0912898T3 (da)
ES (1)	ES2131038T3 (da)
GR (1)	GR990300020T1 (da)
HU (1)	HU228479B1 (da)
IL (1)	IL128042A (da)
NO (1)	NO321466B1 (da)
NZ (1)	NZ333744A (da)
PL (1)	PL189091B1 (da)
PT (1)	PT912898E (da)
SI (1)	SI9720044B (da)
SK (1)	SK284410B6 (da)
WO (1)	WO1998003872A2 (da)

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US6703208B1 (en)	1999-10-20	2004-03-09	Immco Diagnostics	Immunological assay for detection of antibodies in celiac disease
WO2001029090A1 (en) *	1999-10-20	2001-04-26	Immco Diagnostics	Immunological assay for detection of antibodies in celiac disease
CU22968A1 (es) *	2000-06-07	2004-07-14	Ct Ingenieria Genetica Biotech	Procedimiento para la detección de anticuerpos anti transglutaminasa con utilidad en el diagnóstico de la enfermedad celíaca
GB0103024D0 (en) *	2001-02-07	2001-03-21	Rsr Ltd	Assay for Autoantibodies to tissue transglutaminase
FI20010868A0 (fi) *	2001-04-25	2001-04-25	Markku Maeki	Menetelmä ja välineet gluteenin indusoimien tautien havaitsemiseksi
KR100488131B1 (ko) *	2001-07-07	2005-05-06	(주)푸드바이오테크	알레르기 진단용 단백질 칩과 알레르기 유발원의 검출방법 및 알레르기 유발 항체의 검출 방법
GB0117870D0 (en) *	2001-07-21	2001-09-12	Univ Nottingham Trent	Method of diagnosis and kit of parts therefor
US8143210B2 (en)	2002-02-14	2012-03-27	The Board Of Trustees Of The Leland Stanford Junior University	Enzyme treatment of foodstuffs for celiac sprue
AU2003215272B2 (en) *	2002-02-14	2008-04-03	The Board Of Trustees Of The Leland Stanford Junior University	Enzyme treatment of foodstuffs for celiac sprue
US7320788B2 (en) *	2002-02-14	2008-01-22	The Board Of Trustees Of The Leland Stanford Junior University	Enzyme treatment of foodstuffs for Celiac Sprue
RU2234086C2 (ru) *	2002-05-08	2004-08-10	Нижегородский научно-исследовательский институт детской гастроэнтерологии	Способ дифференциальной диагностики целиакии и хронического энтерита у детей с патологией тонкой кишки
AU2003234634A1 (en) *	2002-05-14	2003-12-02	Felix Hausch	Drug therapy for celiac sprue
US7202216B2 (en) *	2002-05-14	2007-04-10	The Board Of Trustees Of The Leland Stanford Junior University	Drug therapy for celiac sprue
US7462688B2 (en) *	2002-05-14	2008-12-09	The Board Of Trustees Of The Leland Stanford Junior University	Peptides for diagnostic and therapeutic methods for celiac sprue
US7265093B2 (en) *	2002-05-14	2007-09-04	The Board Of Trustees Of The Leland Stanford Junior University	Drug therapy for Celiac Sprue
US7776545B2 (en) *	2002-11-20	2010-08-17	The Board Of Trustees Of The Leland Stanford Junior University	Diagnostic method for Celiac Sprue
US7579313B2 (en) *	2003-11-18	2009-08-25	The Board Of Trustees Of The Leland Stanford Junior University	Transglutaminase inhibitors and methods of use thereof
US7628985B2 (en) *	2004-04-26	2009-12-08	The Board Of Regents Of The Leland Stanford Junior University	Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis
US7534426B2 (en) *	2004-04-26	2009-05-19	The Board Of Trustees Of The Leland Stanford Junior University	Glutenase enzyme assays
US7563864B2 (en) *	2004-04-26	2009-07-21	Celiac Sprue Research Foundation	Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten
US20080038760A1 (en) *	2004-06-08	2008-02-14	Method For Decting Anti-Transglutaminase Antibodies	Method for Detecting Anti-Transglutaminase Antibodies
EP2049903B1 (en)	2006-07-25	2015-09-09	Augurix S.A.	An immunochromatography device for the diagnosis of diseases in a sample
ATE515704T1 (de) *	2007-01-26	2011-07-15	Ga Generic Assays Gmbh	Verfahren zum nachweis von antikörpern aus körperflüssigkeiten durch eine immunreaktion mit glykoprotein 2 (gp2) aus zymogenen granula des pankreas zur differentialdiagnose von entzündlichen darmerkrankungen und chronischer pankreatitis
WO2008115411A1 (en) *	2007-03-16	2008-09-25	The Board Of Trustees Of The Leland Stanford Junior University	Combination enzyme therapy for digestion of dietary gluten
EP1978364B1 (en)	2007-04-06	2011-06-01	Zedira GmbH	Transglutaminase 6 as a diagnostic indicator of autoimmune diseases
HU0900199D0 (en) *	2009-04-01	2009-06-29	Debreceni Egyetem	Diagnosis of gluten-induced autoimmune diseases
FR2949782B1 (fr) *	2009-09-04	2015-10-16	Isp Investments Inc	Peptide activateur de la transglutaminase et composition cosmetique ou pharmaceutique le contenant.
WO2013119845A1 (en)	2012-02-07	2013-08-15	Vibrant Holdings, Llc	Substrates, peptide arrays, and methods
US10571466B2 (en)	2012-04-17	2020-02-25	Aeneas Gmbh & Co. Kg	Method for presymptomatic diagnosis of coeliac disease and gluten sensitivity
DE102012007510A1 (de)	2012-04-17	2013-10-17	Aesku.Diagnostics GmbH & Co. KG	Verfahren zur Präsymptomatischen Diagnostik von Zöliakie und Glutensensitivität
US10006909B2 (en)	2012-09-28	2018-06-26	Vibrant Holdings, Llc	Methods, systems, and arrays for biomolecular analysis
US10286376B2 (en)	2012-11-14	2019-05-14	Vibrant Holdings, Llc	Substrates, systems, and methods for array synthesis and biomolecular analysis
US10816553B2 (en)	2013-02-15	2020-10-27	Vibrant Holdings, Llc	Methods and compositions for amplified electrochemiluminescence detection
CN104090102B (zh) *	2014-06-13	2016-08-17	江南大学	冷冻鱼糜中微生物谷氨酰胺转胺酶elisa检测方法
JP6887945B2 (ja)	2014-09-10	2021-06-16	ヴィブラントホールディングスリミテッドライアビリティカンパニー	セリアック病に関するペプチドマイクロアレイおよび新規バイオマーカー
US10538808B2 (en)	2017-05-26	2020-01-21	Vibrant Holdings, Llc	Photoactive compounds and methods for biomolecule detection and sequencing
AU2019266303B2 (en)	2018-05-09	2025-12-18	Vibrant Holdings, Llc	Methods of synthesizing a polynucleotide array using photactivated agents
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1996
- 1996-07-18 DE DE19630557A patent/DE19630557C2/de not_active Revoked
1997
- 1997-07-14 ES ES97939994T patent/ES2131038T3/es not_active Expired - Lifetime
- 1997-07-14 SI SI9720044A patent/SI9720044B/sl unknown
- 1997-07-14 DE DE59705683T patent/DE59705683D1/de not_active Expired - Lifetime
- 1997-07-14 PL PL97331203A patent/PL189091B1/pl unknown
- 1997-07-14 CZ CZ1999117A patent/CZ291662B6/cs not_active IP Right Cessation
- 1997-07-14 PT PT97939994T patent/PT912898E/pt unknown
- 1997-07-14 WO PCT/EP1997/003740 patent/WO1998003872A2/de not_active Ceased
- 1997-07-14 CA CA002260769A patent/CA2260769C/en not_active Expired - Lifetime
- 1997-07-14 SK SK67-99A patent/SK284410B6/sk not_active IP Right Cessation
- 1997-07-14 AT AT97939994T patent/ATE210296T1/de active
- 1997-07-14 CN CNB971965269A patent/CN1138146C/zh not_active Expired - Lifetime
- 1997-07-14 IL IL128042A patent/IL128042A/en not_active IP Right Cessation
- 1997-07-14 BR BRPI9710500-7A patent/BR9710500B1/pt not_active IP Right Cessation
- 1997-07-14 AU AU42011/97A patent/AU718797B2/en not_active Expired
- 1997-07-14 NZ NZ333744A patent/NZ333744A/xx not_active IP Right Cessation
- 1997-07-14 EP EP97939994A patent/EP0912898B1/de not_active Expired - Lifetime
- 1997-07-14 DK DK97939994T patent/DK0912898T3/da active
- 1997-07-14 HU HU0202779A patent/HU228479B1/hu unknown
1999
- 1999-01-01 GR GR990300020T patent/GR990300020T1/el unknown
- 1999-01-13 US US09/229,716 patent/US6319726B1/en not_active Expired - Lifetime
- 1999-01-15 NO NO19990190A patent/NO321466B1/no not_active IP Right Cessation
2001
- 2001-08-08 US US09/925,076 patent/US20020076834A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE59705683D1 (de)	2002-01-17
GR990300020T1 (en)	1999-06-30
HK1021025A1 (en)	2000-05-26
DK0912898T3 (da)	2002-04-08
IL128042A (en)	2007-06-17
SK284410B6 (sk)	2005-03-04
CN1138146C (zh)	2004-02-11
SI9720044B (sl)	2003-02-28
WO1998003872A3 (de)	1998-03-12
CN1225723A (zh)	1999-08-11
AU718797B2 (en)	2000-04-20
CZ291662B6 (cs)	2003-04-16
ATE210296T1 (de)	2001-12-15
BR9710500B1 (pt)	2009-05-05
AU4201197A (en)	1998-02-10
US6319726B1 (en)	2001-11-20
EP0912898B1 (de)	2001-12-05
EP0912898A2 (de)	1999-05-06
ES2131038T3 (es)	2002-09-01
HUP0202779A2 (hu)	2002-12-28
SK6799A3 (en)	2000-05-16
PL189091B1 (pl)	2005-06-30
ES2131038T1 (es)	1999-07-16
US20020076834A1 (en)	2002-06-20
NZ333744A (en)	2000-03-27
PL331203A1 (en)	1999-07-05
HU228479B1 (en)	2013-03-28
BR9710500A (pt)	2000-01-18
PT912898E (pt)	2002-05-31
NO990190L (no)	1999-03-15
IL128042A0 (en)	1999-11-30
CZ11799A3 (cs)	1999-07-14
SI9720044A (sl)	1999-08-31
WO1998003872A2 (de)	1998-01-29
CA2260769C (en)	2005-09-06
HUP0202779A3 (en)	2009-07-28
DE19630557A1 (de)	1998-01-29
NO990190D0 (no)	1999-01-15
CA2260769A1 (en)	1998-01-29
DE19630557C2 (de)	1998-07-02

Legal Events

Date	Code	Title	Description
2017-07-31	MK1K	Patent expired

Publication	Publication Date	Title
NO321466B1 (no)	2006-05-15	Fremgangsmate for immunologisk pavisning av antistoffer rettet mot vevstransglutaminase (tTG), oralt farmasoytisk middel inneholdende tTG, samt anvendelse av tTG-inneholdende forbindelser.
US7585511B2 (en)	2009-09-08	Apolipoprotein L-I and/or derivated polypeptide for the treatment of and/or the prevention of diseases induced by trypanosoma
Quarsten et al.	1999	HLA binding and T cell recognition of a tissue transglutaminase‐modified gliadin epitope
CA2502700C (en)	2017-01-17	Diagnostic method for celiac sprue
Schuppan et al.	2001	Celiac disease and its link to type 1 diabetes mellitus.
Elli et al.	2012	Immunological effects of transglutaminase-treated gluten in coeliac disease
EP3061766B1 (en)	2019-12-25	Compositions and methods for the treatment of disorders involving epithelial cell apoptosis
EA037603B1 (ru)	2021-04-20	Композиции и способы для лечения целиакии спру
WO1999056698A2 (en)	1999-11-11	Treatment of celiac disease
WO2010084851A1 (ja)	2010-07-29	イミュノグロブリン結合能を有するペプチド
CA2906044A1 (en)	2014-09-25	Placebo-controlled gluten challenge method
Lühn et al.	2004	Identification and molecular cloning of a functional GDP-fucose transporter in Drosophila melanogaster
Friis	1996	Coeliac Disease. Pathogenesis and clinical aspects
HK1021025B (en)	2004-12-10	Process for in vitro detecting the presence or absence of antibodies to anti-tissue transglutinase from body fluids
Loppinet	2024	Discovery and Engineering the TG2/LRP-1 Pathway for Lysosomal Delivery of Molecular Cargo: Implications for Celiac Disease
Cronin et al.	1998	A significant step in the celiac puzzle
US20050221302A1 (en)	2005-10-06	Tissue transglutaminase
Gelisgen	2007	All Other Topics
HK1228417A1 (en)	2017-11-03	Compositions and methods for the treatment of disorders involving epithelial cell apoptosis
WO2001090195A1 (en)	2001-11-29	Immunoassay method for x-type phospholipase a¿2?