NO323610B1 - Polypeptider og peptider som omfatter en hemoglobin-alfa-kjede eller deler derav, farmasoytiske blandinger som omfatter dem, samt anvendelser og fremgangsmater som involverer stamcelleproliferasjonsinhiberende og -stimulerende mengder av polypeptidene og peptidene. - Google Patents

Polypeptider og peptider som omfatter en hemoglobin-alfa-kjede eller deler derav, farmasoytiske blandinger som omfatter dem, samt anvendelser og fremgangsmater som involverer stamcelleproliferasjonsinhiberende og -stimulerende mengder av polypeptidene og peptidene. Download PDF

Info

Publication number
NO323610B1
NO323610B1 NO19984628A NO984628A NO323610B1 NO 323610 B1 NO323610 B1 NO 323610B1 NO 19984628 A NO19984628 A NO 19984628A NO 984628 A NO984628 A NO 984628A NO 323610 B1 NO323610 B1 NO 323610B1
Authority
NO
Norway
Prior art keywords
hemoglobin
cells
chain
polypeptide
stem cell
Prior art date
Application number
NO19984628A
Other languages
English (en)
Norwegian (no)
Other versions
NO984628L (no
NO984628D0 (no
Inventor
Irena Tsyrlova
Stephen D Wolpe
Original Assignee
Pro Neuron Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pro Neuron Inc filed Critical Pro Neuron Inc
Publication of NO984628D0 publication Critical patent/NO984628D0/no
Publication of NO984628L publication Critical patent/NO984628L/no
Publication of NO323610B1 publication Critical patent/NO323610B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • C07K14/805Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO19984628A 1996-04-03 1998-10-02 Polypeptider og peptider som omfatter en hemoglobin-alfa-kjede eller deler derav, farmasoytiske blandinger som omfatter dem, samt anvendelser og fremgangsmater som involverer stamcelleproliferasjonsinhiberende og -stimulerende mengder av polypeptidene og peptidene. NO323610B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/627,173 US5861483A (en) 1996-04-03 1996-04-03 Inhibitor of stem cell proliferation and uses thereof
PCT/US1997/005601 WO1997036922A1 (en) 1996-04-03 1997-04-03 Inhibitor and stimulator of stem cell proliferation and uses thereof

Publications (3)

Publication Number Publication Date
NO984628D0 NO984628D0 (no) 1998-10-02
NO984628L NO984628L (no) 1998-12-01
NO323610B1 true NO323610B1 (no) 2007-06-18

Family

ID=24513524

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19984628A NO323610B1 (no) 1996-04-03 1998-10-02 Polypeptider og peptider som omfatter en hemoglobin-alfa-kjede eller deler derav, farmasoytiske blandinger som omfatter dem, samt anvendelser og fremgangsmater som involverer stamcelleproliferasjonsinhiberende og -stimulerende mengder av polypeptidene og peptidene.

Country Status (16)

Country Link
US (4) US5861483A (ru)
EP (2) EP0891377B1 (ru)
JP (3) JP4241927B2 (ru)
KR (1) KR20040088588A (ru)
CN (2) CN1264856C (ru)
AT (1) ATE311406T1 (ru)
AU (1) AU727023B2 (ru)
CA (1) CA2249716A1 (ru)
DE (1) DE69734766T2 (ru)
ES (1) ES2252781T3 (ru)
IL (2) IL126395A0 (ru)
NO (1) NO323610B1 (ru)
NZ (1) NZ331895A (ru)
RU (1) RU2292352C9 (ru)
UA (2) UA74128C2 (ru)
WO (1) WO1997036922A1 (ru)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU694111B2 (en) 1993-03-31 1998-07-16 Pro-Neuron, Inc. Inhibitor of stem cell proliferation and uses thereof
US5939391A (en) * 1993-03-31 1999-08-17 Pro-Neuron, Inc. Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
US6610654B2 (en) 1993-03-31 2003-08-26 Wellstat Therapeutics Corporation Inhibitor of stem cell proliferation and uses thereof
US5861483A (en) 1996-04-03 1999-01-19 Pro-Neuron, Inc. Inhibitor of stem cell proliferation and uses thereof
AUPO089396A0 (en) * 1996-07-09 1996-08-01 Howard Florey Institute Of Experimental Physiology And Medicine Neuroactive peptide
EP0939644B1 (en) * 1996-08-27 2004-01-14 Hemosol Inc. Enhanced stimulation of erythropoiesis
DE19708454A1 (de) * 1997-02-17 1998-08-27 Schering Ag Die Proliferation von Zellen inhibierendes Peptid und dessen Verwendung
US8197430B1 (en) * 1998-05-22 2012-06-12 Biopheresis Technologies, Inc. Method and system to remove cytokine inhibitor in patients
US6620382B1 (en) * 1998-05-22 2003-09-16 Biopheresis Technologies, Llc. Method and compositions for treatment of cancers
ATE284220T1 (de) * 1999-02-03 2004-12-15 Idm Immuno Designed Molecules Makrophagenhaltige zusammensetzung mit antiinfektiösen und hematopoietischen eigenschaften sowie deren herstellungsmethode
US6379708B1 (en) * 1999-11-20 2002-04-30 Cytologic, Llc Method for enhancing immune responses in mammals
EP1322323A4 (en) 2000-09-11 2004-07-28 Therapro Technologies Inc THIONIN AS AN ANTINEOPLASTIC AND IMMUNO-STIMULATING AGENT
AU2002241859B2 (en) 2001-01-10 2007-07-19 St. Vincent's Institute Of Medical Research sFRP and peptide motifs that interact with sFRP and methods of their use
SG142165A1 (en) * 2001-07-13 2008-05-28 Cms Peptides Patent Holding Co Biologically active peptides
CN1216070C (zh) * 2001-07-13 2005-08-24 一泰医药研究(深圳)有限公司 序列号20的生物活性肽
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
RU2245162C2 (ru) * 2003-01-04 2005-01-27 Козлов Владимир Александрович Способ терапии инфаркта миокарда
WO2005107802A2 (en) * 2004-04-30 2005-11-17 Biopheresis Technologies, Llc Method and system to remove soluble tnfr1, tnfr2, and il2 in patients
FR2872040B1 (fr) * 2004-06-23 2006-09-22 Centre Nat Rech Scient Cnrse Utilisation cosmetique d'au moins un tetrapeptide naturel ac-n-ser-asp-lys-pro- ou un de ses analogues en tant qu'agent antivieillissement et restructurant de la peau
EP1778271B1 (en) * 2004-08-18 2008-10-22 IPF Pharmaceuticals GmbH Peptides for the treatment of herpes virus infections
US7850960B2 (en) * 2004-12-30 2010-12-14 University Of Washington Methods for regulation of stem cells
KR100621354B1 (ko) * 2005-06-14 2006-09-08 광주과학기술원 유비퀴틴을 이용한 아밀로이드-베타 펩티드의 제조방법
NZ591827A (en) 2005-07-26 2012-10-26 Cms Peptides Patent Holding Company Ltd Biologically active peptides comprising PTTKTYFPHF and their uses in the manufacture of a medicament for modulating immune reaction in a radiotherapy-induced immuno-compromised subject
US20070065514A1 (en) * 2005-09-22 2007-03-22 Howell Mark D Method for enhancing immune responses in mammals
CN1994464B (zh) * 2005-12-31 2010-05-05 中国科学院大连化学物理研究所 一种血管紧张素i转换酶抑制剂及其应用
RU2317074C1 (ru) * 2006-03-16 2008-02-20 Общество с ограниченной ответственностью "МБФ" Ингибитор дифференцировки кроветворных клеток-предшественников
US20080075690A1 (en) * 2006-09-22 2008-03-27 Mark Douglas Howell Method for enhancing immune responses in mammals
WO2008039874A2 (en) 2006-09-26 2008-04-03 Cedars-Sinai Medical Center Cancer stem cell antigen vaccines and methods
WO2008144019A2 (en) * 2007-05-18 2008-11-27 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Suppression of allergic inflammation by ascaris heme-binding protein (hbp)
US20100204149A1 (en) * 2007-09-11 2010-08-12 Dorian Bevec Use of octreotide as a therapeutic agent
KR20100069651A (ko) * 2007-09-11 2010-06-24 몬도바이오테크 래보래토리즈 아게 Hcmv 감염의 치료를 위한 치료제로서의 bubuc 및 임의의 eaa-mart1(26-35)의 용도
CA2698666A1 (en) * 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
PT2113253E (pt) * 2008-04-30 2010-06-15 Immatics Biotechnologies Gmbh Formulações novas de peptídeos associados a tumores que se ligam a moléculas de classe i ou ii do antígeno leucocitário humano (hla) para vacinas
RU2374262C1 (ru) * 2008-05-22 2009-11-27 Ибмед Холдингс Лимитед Олигопептид, обладающий активностью фактора стволовых клеток csf по отношению к дифференцировке тимоцитов
CN102209552A (zh) * 2008-11-07 2011-10-05 联合技术Ut股份公司 含有白介素-1和肽的组合物
RU2412708C2 (ru) * 2008-11-27 2011-02-27 Федеральное Государственное Учреждение "Кировский Научно-Исследовательский Институт Гематологии И Переливания Крови Федерального Агентства По Высокотехнологичной Медицинской Помощи" Способ индукции ремиссии у больных приобретенной апластической анемией
WO2010091052A2 (en) 2009-02-03 2010-08-12 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
WO2010096264A2 (en) 2009-02-03 2010-08-26 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
EA201101639A1 (ru) * 2009-05-20 2012-06-29 Юниверсите Де Женев Ингибиторы митохондриальной активности клеток, инициирующих рак, и их применение
RU2395251C1 (ru) * 2009-05-25 2010-07-27 Государственное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарева" Способ стимулирования миелопоэза животных
US20110070269A1 (en) * 2009-09-24 2011-03-24 Therapro Technologies, Inc. Lipopolysaccharide isolated from pyrularia tissue and/or pyrularia-associated bacteria and uses thereof
RU2452501C2 (ru) * 2010-08-31 2012-06-10 Александр Владимирович Балюра Сенситин для эритроцитарного диагностикума для диагностики злокачественных новообразований и способ его получения, эритроцитарный диагностикум для диагностики злокачественных новообразований и способ его получения и способ диагностики наличия злокачественных новообразований с использованием указанного эритроцитарного диагностикума
AU2010365057B2 (en) * 2010-12-08 2016-12-22 Viacyte, Inc. Agents and methods for inhibiting human pluripotent stem cell growth
WO2012159044A1 (en) * 2011-05-18 2012-11-22 Wellstat Therapeutics Corporation Stem cell mobilization and tissue repair and regeneration
US9428552B2 (en) 2012-11-19 2016-08-30 Wellstat Therapeutics Corporation Stem cell mobilization and tissue repair and regeneration
CN103804484B (zh) * 2014-01-24 2016-03-16 南京必优康生物技术有限公司 一种网红细胞生长因子及其制备方法和应用
CN106317177A (zh) * 2015-06-23 2017-01-11 首都医科大学 Gly-Phe-Pro,其合成,活性和应用
CN107899001B (zh) * 2017-05-16 2021-08-06 陈娟娟 Notch配体蛋白在制备治疗肿瘤化疗导致骨髓抑制药物方面及早期预后判断方面的应用
CN109293737B (zh) * 2018-09-27 2020-10-27 华南理工大学 一种抗皮肤衰老的四肽及其用途

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1142466A (en) * 1979-01-09 1983-03-08 National Research Development Corporation Cell lines
US4683194A (en) * 1984-05-29 1987-07-28 Cetus Corporation Method for detection of polymorphic restriction sites and nucleic acid sequences
US5132213A (en) * 1986-10-02 1992-07-21 Massachusetts Institute Of Technology Method for producing proteins and polypeptides using ubiquitin fusions
US5196321A (en) 1986-10-02 1993-03-23 Massachusetts Institute Of Technology Methods for in vitro cleavage of ubiquitin fusion proteins
GB8711614D0 (en) * 1987-05-16 1987-06-24 Medical Res Council Proteins
US5449759A (en) * 1987-05-16 1995-09-12 Somatogen, Inc. Hemoglobins with intersubunit desulfide bonds
US5545727A (en) * 1989-05-10 1996-08-13 Somatogen, Inc. DNA encoding fused di-alpha globins and production of pseudotetrameric hemoglobin
DE69028448T2 (de) * 1989-05-10 1997-02-06 Medical Research Council, London Herstellung von Hämoglobin und Analogen davon durch Bakterien oder Hefen
CA2064558C (en) * 1989-09-25 2001-01-30 Ian B. Pragnell Method for inhibiting growth of stem cells
EP0531404B1 (en) * 1990-05-09 1995-04-19 Massachusetts Institute Of Technology Ubiquitin-specific protease
US5239061A (en) * 1990-06-20 1993-08-24 Research Corporation Technologies, Inc. Modified human hemoglobin, blood substitutes containing the same, and vectors for expressing the modified hemoglobin
CA2098818A1 (en) * 1990-12-20 1992-06-21 Tim Townes Transgenic, cross-linked hemoglobin
AU2140492A (en) 1991-05-14 1992-12-30 Biopure Corporation Use of hemoglobin in a method for the treatment of tumors with chemotherapeutic agents
US5334706A (en) 1992-01-30 1994-08-02 Baxter International Administration of low dose hemoglobin to increase perfusion
JPH07507921A (ja) 1992-06-12 1995-09-07 ディーエヌエックス コーポレーション トランスジェニックブタにおけるヒトヘモグロビンの生産
US5786334A (en) * 1992-08-14 1998-07-28 Technology Resources International, Inc. Hexapeptide having immunostimulatory activity
DE4228458A1 (de) * 1992-08-27 1994-06-01 Beiersdorf Ag Multicistronische Expressionseinheiten und deren Verwendung
AU694111B2 (en) 1993-03-31 1998-07-16 Pro-Neuron, Inc. Inhibitor of stem cell proliferation and uses thereof
US5939391A (en) 1993-03-31 1999-08-17 Pro-Neuron, Inc. Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
US6610654B2 (en) * 1993-03-31 2003-08-26 Wellstat Therapeutics Corporation Inhibitor of stem cell proliferation and uses thereof
US5631219A (en) 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
FR2719240B1 (fr) * 1994-04-29 1996-06-07 Elf Antar France Procédé de traitement des suspensions huileuses.
US5861483A (en) * 1996-04-03 1999-01-19 Pro-Neuron, Inc. Inhibitor of stem cell proliferation and uses thereof
US6280739B1 (en) * 1996-04-18 2001-08-28 Genetics Institute, Inc. Method of inhibiting angiogenesis using secreted proteins

Also Published As

Publication number Publication date
NO984628L (no) 1998-12-01
US7115267B2 (en) 2006-10-03
EP0891377B1 (en) 2005-11-30
AU727023B2 (en) 2000-11-30
NO984628D0 (no) 1998-10-02
RU2292352C9 (ru) 2007-05-10
CN1264856C (zh) 2006-07-19
IL176642A0 (en) 2006-10-31
AU2439197A (en) 1997-10-22
JP2000508633A (ja) 2000-07-11
RU2292352C2 (ru) 2007-01-27
CN1174996C (zh) 2004-11-10
US20060166863A1 (en) 2006-07-27
EP0891377A4 (en) 2003-01-02
JP2012046537A (ja) 2012-03-08
CA2249716A1 (en) 1997-10-09
KR20040088588A (ko) 2004-10-16
WO1997036922A1 (en) 1997-10-09
JP2009013178A (ja) 2009-01-22
NZ331895A (en) 2000-07-28
IL126395A0 (en) 1999-05-09
CN1541706A (zh) 2004-11-03
ES2252781T3 (es) 2006-05-16
EP1820805A3 (en) 2007-11-07
US5861483A (en) 1999-01-19
DE69734766T2 (de) 2006-09-14
HK1069985A1 (en) 2005-06-10
UA74128C2 (ru) 2005-11-15
DE69734766D1 (de) 2006-01-05
JP4241927B2 (ja) 2009-03-18
EP0891377A1 (en) 1999-01-20
US20040167060A1 (en) 2004-08-26
CN1220670A (zh) 1999-06-23
ATE311406T1 (de) 2005-12-15
UA85036C2 (ru) 2008-12-25
US6784155B1 (en) 2004-08-31
EP1820805A2 (en) 2007-08-22

Similar Documents

Publication Publication Date Title
US6784155B1 (en) Inhibitor and stimulator of stem cell proliferation and uses thereof
WO1997036922A9 (en) Inhibitor and stimulator of stem cell proliferation and uses thereof
JP4188279B2 (ja) 幹細胞増殖インヒビターおよびその使用
US6610654B2 (en) Inhibitor of stem cell proliferation and uses thereof
AU768081B2 (en) Inhibitor and stimulator of stem cell proliferation and uses thereof
KR100619599B1 (ko) 간세포증식의억제제및자극제및그것들의용도
NZ504512A (en) Peptide from alpha-hemoglobin as a stimulator of stem cell proliferation and used thereof
EP1362596A2 (en) Inhibitor of stem cell proliferation and uses thereof
MXPA98008178A (es) Inhibidor y estimulador de la proliferación de células totipotentes y sus usos
HK1006642B (en) Inhibitor of stem cell proliferation and uses thereof

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees