NO324131B1 - Fremgangsmate for fremstilling av alginat som har et hoyt mannuronsyre-innhold - Google Patents
Fremgangsmate for fremstilling av alginat som har et hoyt mannuronsyre-innhold Download PDFInfo
- Publication number
- NO324131B1 NO324131B1 NO20015874A NO20015874A NO324131B1 NO 324131 B1 NO324131 B1 NO 324131B1 NO 20015874 A NO20015874 A NO 20015874A NO 20015874 A NO20015874 A NO 20015874A NO 324131 B1 NO324131 B1 NO 324131B1
- Authority
- NO
- Norway
- Prior art keywords
- alginate
- mannuronic acid
- solution
- extraction
- acid
- Prior art date
Links
- 229920000615 alginic acid Polymers 0.000 title claims abstract description 63
- 235000010443 alginic acid Nutrition 0.000 title claims abstract description 62
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 title claims abstract description 49
- 229940072056 alginate Drugs 0.000 title claims abstract description 48
- 238000000034 method Methods 0.000 title claims abstract description 27
- 230000008569 process Effects 0.000 title claims abstract description 11
- AEMOLEFTQBMNLQ-VANFPWTGSA-N D-mannopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H]1O AEMOLEFTQBMNLQ-VANFPWTGSA-N 0.000 title claims description 28
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 title claims description 28
- 238000002360 preparation method Methods 0.000 title description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 241000195493 Cryptophyta Species 0.000 claims abstract description 18
- 238000004519 manufacturing process Methods 0.000 claims abstract description 15
- 238000001914 filtration Methods 0.000 claims abstract description 12
- 238000003756 stirring Methods 0.000 claims abstract description 10
- 238000000926 separation method Methods 0.000 claims abstract description 7
- 239000000725 suspension Substances 0.000 claims abstract description 7
- 241001474374 Blennius Species 0.000 claims abstract description 5
- 239000011343 solid material Substances 0.000 claims abstract description 4
- 238000000605 extraction Methods 0.000 claims description 31
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 10
- 150000003839 salts Chemical class 0.000 claims description 10
- 238000001556 precipitation Methods 0.000 claims description 9
- 239000011780 sodium chloride Substances 0.000 claims description 5
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 3
- 239000001110 calcium chloride Substances 0.000 claims description 3
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 3
- 235000011148 calcium chloride Nutrition 0.000 claims description 3
- 238000011084 recovery Methods 0.000 claims description 3
- 230000001105 regulatory effect Effects 0.000 claims 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 39
- 239000000463 material Substances 0.000 description 19
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 12
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 11
- 239000000835 fiber Substances 0.000 description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 9
- 239000002253 acid Substances 0.000 description 9
- 239000004744 fabric Substances 0.000 description 9
- 230000008961 swelling Effects 0.000 description 8
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 6
- 238000001035 drying Methods 0.000 description 6
- 238000006386 neutralization reaction Methods 0.000 description 6
- 235000017550 sodium carbonate Nutrition 0.000 description 6
- 229910000029 sodium carbonate Inorganic materials 0.000 description 6
- 239000007858 starting material Substances 0.000 description 6
- 238000003916 acid precipitation Methods 0.000 description 5
- 239000002244 precipitate Substances 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 241000894007 species Species 0.000 description 5
- 241000199919 Phaeophyceae Species 0.000 description 4
- 239000000783 alginic acid Substances 0.000 description 4
- 229960001126 alginic acid Drugs 0.000 description 4
- 150000004781 alginic acids Chemical class 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 4
- 238000003825 pressing Methods 0.000 description 4
- 241000512260 Ascophyllum Species 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 238000013019 agitation Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000003760 magnetic stirring Methods 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000007873 sieving Methods 0.000 description 3
- MSXHSNHNTORCAW-MPGIDXPLSA-M sodium;(3s,4s,5s,6r)-3,4,5,6-tetrahydroxyoxane-2-carboxylate Chemical compound [Na+].O[C@@H]1OC(C([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O MSXHSNHNTORCAW-MPGIDXPLSA-M 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 241000172184 Durvillaea antarctica Species 0.000 description 2
- 241000195522 Fucales Species 0.000 description 2
- 241001466453 Laminaria Species 0.000 description 2
- 241001512709 Lessonia <stramenopiles> Species 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 239000011362 coarse particle Substances 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 229920001519 homopolymer Polymers 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 235000011837 pasties Nutrition 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000010561 standard procedure Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- AEMOLEFTQBMNLQ-AZLKCVHYSA-N (2r,3s,4s,5s,6r)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid Chemical compound O[C@@H]1O[C@@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H]1O AEMOLEFTQBMNLQ-AZLKCVHYSA-N 0.000 description 1
- 241000512259 Ascophyllum nodosum Species 0.000 description 1
- 241000589151 Azotobacter Species 0.000 description 1
- 241000589149 Azotobacter vinelandii Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- AEMOLEFTQBMNLQ-BZINKQHNSA-N D-Guluronic Acid Chemical compound OC1O[C@H](C(O)=O)[C@H](O)[C@@H](O)[C@H]1O AEMOLEFTQBMNLQ-BZINKQHNSA-N 0.000 description 1
- 241000304827 Durvillaea potatorum Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 241000589774 Pseudomonas sp. Species 0.000 description 1
- 229920001131 Pulp (paper) Polymers 0.000 description 1
- FJWGYAHXMCUOOM-QHOUIDNNSA-N [(2s,3r,4s,5r,6r)-2-[(2r,3r,4s,5r,6s)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2r,3r,4s,5r,6s)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O)O[C@H]1[C@@H]([C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@@H](CO[N+]([O-])=O)O1)O[N+]([O-])=O)CO[N+](=O)[O-])[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O FJWGYAHXMCUOOM-QHOUIDNNSA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- AEMOLEFTQBMNLQ-UHFFFAOYSA-N beta-D-galactopyranuronic acid Natural products OC1OC(C(O)=O)C(O)C(O)C1O AEMOLEFTQBMNLQ-UHFFFAOYSA-N 0.000 description 1
- 229920001222 biopolymer Polymers 0.000 description 1
- 239000000648 calcium alginate Substances 0.000 description 1
- 235000010410 calcium alginate Nutrition 0.000 description 1
- 229960002681 calcium alginate Drugs 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 230000008570 general process Effects 0.000 description 1
- 125000005613 guluronic acid group Chemical group 0.000 description 1
- 239000000416 hydrocolloid Substances 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 241001478887 unidentified soil bacteria Species 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
- A23L29/256—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20015874A NO324131B1 (no) | 2001-11-30 | 2001-11-30 | Fremgangsmate for fremstilling av alginat som har et hoyt mannuronsyre-innhold |
| CNB028237072A CN100467492C (zh) | 2001-11-30 | 2002-11-21 | 具有高甘露糖醛酸含量的藻酸盐的制备方法 |
| EP02799859A EP1461363B1 (de) | 2001-11-30 | 2002-11-21 | Verfahren zur herstellung von alginat mit hohem mannuronsäuregehalt |
| PCT/NO2002/000431 WO2003046199A2 (en) | 2001-11-30 | 2002-11-21 | Process for the production of alginate having a high mannuronic acid-content |
| AT02799859T ATE540982T1 (de) | 2001-11-30 | 2002-11-21 | Verfahren zur herstellung von alginat mit hohem mannuronsäuregehalt |
| CNA2009100034736A CN101514235A (zh) | 2001-11-30 | 2002-11-21 | 具有高甘露糖醛酸含量的藻酸盐的制备方法 |
| US10/497,213 US7838641B2 (en) | 2001-11-30 | 2002-11-21 | Process for the production of alginate having a high mannuronic acid-content |
| CA2467510A CA2467510C (en) | 2001-11-30 | 2002-11-21 | Process for the production of alginate having a high mannuronic acid-content |
| AU2002364492A AU2002364492A1 (en) | 2001-11-30 | 2002-11-21 | Process for the production of alginate having a high mannuronic acid-content |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20015874A NO324131B1 (no) | 2001-11-30 | 2001-11-30 | Fremgangsmate for fremstilling av alginat som har et hoyt mannuronsyre-innhold |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20015874D0 NO20015874D0 (no) | 2001-11-30 |
| NO20015874L NO20015874L (no) | 2003-06-02 |
| NO324131B1 true NO324131B1 (no) | 2007-09-03 |
Family
ID=19913091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20015874A NO324131B1 (no) | 2001-11-30 | 2001-11-30 | Fremgangsmate for fremstilling av alginat som har et hoyt mannuronsyre-innhold |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7838641B2 (de) |
| EP (1) | EP1461363B1 (de) |
| CN (2) | CN101514235A (de) |
| AT (1) | ATE540982T1 (de) |
| AU (1) | AU2002364492A1 (de) |
| CA (1) | CA2467510C (de) |
| NO (1) | NO324131B1 (de) |
| WO (1) | WO2003046199A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050087902A1 (en) * | 2003-10-28 | 2005-04-28 | Isaac Farr | Alginate-based materials, methods of application thereof, and systems for using the alginate-based materials |
| CN100425623C (zh) * | 2006-09-28 | 2008-10-15 | 青岛明月海藻集团有限公司 | 一种啤酒专用藻酸丙二醇酯的生产方法 |
| US20090060943A1 (en) * | 2007-08-31 | 2009-03-05 | O'mara Brendan Joseph | Syndrome X Composition and Method of Lowering Blood Pressure and Glycemic Index |
| HUE034051T2 (en) | 2007-11-27 | 2018-01-29 | Algipharma As | Use of alginate-containing oligomers to combat biofilms |
| US9175322B2 (en) * | 2008-04-29 | 2015-11-03 | Marshall University Research Corporation | Stable bacterial cultures for producing alginates |
| ES2444541T3 (es) | 2009-06-03 | 2014-02-25 | Algipharma As | Oligómeros de alginato para usar para superar la multirresistencia a fármacos en bacterias |
| AU2012269703A1 (en) * | 2011-06-13 | 2013-12-19 | Al-G Technologies Inc. | Method using immobilized algae for production and harvest of algal biomass and products |
| NL2012987B1 (en) * | 2014-06-12 | 2016-07-04 | Univ Delft Tech | Biopolymer extraction. |
| CL2015001932A1 (es) | 2015-07-07 | 2015-11-20 | Jose Zaldivar Larrain Francisco | Material que comprende una mezcla de algas pardas, material celulósico y adhesivo, y proceso para su elaboración. |
| AU2017385354B2 (en) | 2016-12-30 | 2021-06-03 | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Method of degrading polysaccharide using ozone |
| CN107880150A (zh) * | 2017-12-05 | 2018-04-06 | 四川大学 | 一种提高海藻酸盐中古洛糖醛酸单元含量的方法 |
| GB202109772D0 (en) * | 2021-07-06 | 2021-08-18 | Alginor Asa | Method |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2128551A (en) * | 1934-01-11 | 1938-08-30 | Algin Corp Of America | Method of treating seaweed |
| GB862702A (en) | 1958-11-03 | 1961-03-15 | Marcus Friedrich Karl | Improvements in or relating to methods for the production of alginic acid and alginates from algae |
| US3396158A (en) * | 1964-11-02 | 1968-08-06 | Norsk Inst For Tang Og Tarefor | Preparation of alginic acid by extraction of algae |
| CN1030454C (zh) * | 1988-10-30 | 1995-12-06 | 青岛海洋大学 | 制取甘露糖醛酸丙酯硫酸酯钠盐的方法 |
| US5596084A (en) * | 1994-10-05 | 1997-01-21 | Monsanto Company | Alginate gels |
| NO305033B1 (no) * | 1997-05-09 | 1999-03-22 | Algipharma As | Fremgangsmate for fremstilling av uronsyreblokker fra alginat |
| DE19836960A1 (de) | 1998-08-14 | 2000-02-17 | Ulrich Zimmermann | Verfahren zur Gewinnung hochgereinigter Alginate |
| KR100501584B1 (ko) | 2000-02-03 | 2005-07-18 | (주)케이비피 | 저분자 폴리만유로네이트의 제조방법, 혈청지질개선제로서의 이의 신규 용도 및 이를 함유하는 기능성식품 및 건강 보조 식품 |
| JP2002119226A (ja) | 2000-10-13 | 2002-04-23 | Yoko Shiga | 褐藻類の溶解およびその成分の抽出法と生成物の利用法 |
-
2001
- 2001-11-30 NO NO20015874A patent/NO324131B1/no not_active IP Right Cessation
-
2002
- 2002-11-21 AU AU2002364492A patent/AU2002364492A1/en not_active Abandoned
- 2002-11-21 CA CA2467510A patent/CA2467510C/en not_active Expired - Fee Related
- 2002-11-21 AT AT02799859T patent/ATE540982T1/de active
- 2002-11-21 WO PCT/NO2002/000431 patent/WO2003046199A2/en not_active Ceased
- 2002-11-21 CN CNA2009100034736A patent/CN101514235A/zh active Pending
- 2002-11-21 EP EP02799859A patent/EP1461363B1/de not_active Expired - Lifetime
- 2002-11-21 US US10/497,213 patent/US7838641B2/en not_active Expired - Fee Related
- 2002-11-21 CN CNB028237072A patent/CN100467492C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO20015874D0 (no) | 2001-11-30 |
| CN100467492C (zh) | 2009-03-11 |
| US20050038237A1 (en) | 2005-02-17 |
| ATE540982T1 (de) | 2012-01-15 |
| WO2003046199A2 (en) | 2003-06-05 |
| CA2467510C (en) | 2011-07-12 |
| CN1596270A (zh) | 2005-03-16 |
| EP1461363A2 (de) | 2004-09-29 |
| WO2003046199A3 (en) | 2003-08-14 |
| CN101514235A (zh) | 2009-08-26 |
| AU2002364492A1 (en) | 2003-06-10 |
| US7838641B2 (en) | 2010-11-23 |
| NO20015874L (no) | 2003-06-02 |
| AU2002364492A8 (en) | 2003-06-10 |
| EP1461363B1 (de) | 2012-01-11 |
| CA2467510A1 (en) | 2003-06-05 |
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