NO326852B1 - Nye galeniske formuleringer av meloksicam for oral administrering, samt fremgangsmate for fremstilling derav. - Google Patents

Nye galeniske formuleringer av meloksicam for oral administrering, samt fremgangsmate for fremstilling derav. Download PDF

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Publication number
NO326852B1
NO326852B1 NO20004823A NO20004823A NO326852B1 NO 326852 B1 NO326852 B1 NO 326852B1 NO 20004823 A NO20004823 A NO 20004823A NO 20004823 A NO20004823 A NO 20004823A NO 326852 B1 NO326852 B1 NO 326852B1
Authority
NO
Norway
Prior art keywords
meloxicam
salt
meglumine
meglumine salt
crystalline
Prior art date
Application number
NO20004823A
Other languages
English (en)
Norwegian (no)
Other versions
NO20004823L (no
NO20004823D0 (no
Inventor
Dietrich Tuerck
Thomas Bock
Paul Sagmueller
Peter Sieger
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of NO20004823D0 publication Critical patent/NO20004823D0/no
Publication of NO20004823L publication Critical patent/NO20004823L/no
Publication of NO326852B1 publication Critical patent/NO326852B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NO20004823A 1998-03-27 2000-09-26 Nye galeniske formuleringer av meloksicam for oral administrering, samt fremgangsmate for fremstilling derav. NO326852B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98105569A EP0945134A1 (de) 1998-03-27 1998-03-27 Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation
PCT/EP1999/001949 WO1999049867A1 (de) 1998-03-27 1999-03-23 Neue galenische zubereitungsformen von meloxicam zur oralen applikation

Publications (3)

Publication Number Publication Date
NO20004823D0 NO20004823D0 (no) 2000-09-26
NO20004823L NO20004823L (no) 2000-11-22
NO326852B1 true NO326852B1 (no) 2009-03-02

Family

ID=8231652

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004823A NO326852B1 (no) 1998-03-27 2000-09-26 Nye galeniske formuleringer av meloksicam for oral administrering, samt fremgangsmate for fremstilling derav.

Country Status (24)

Country Link
US (1) US6869948B1 (da)
EP (2) EP0945134A1 (da)
JP (1) JP3639532B2 (da)
KR (1) KR100589299B1 (da)
CN (1) CN1163231C (da)
AR (1) AR016197A1 (da)
AT (1) ATE254920T1 (da)
AU (1) AU762322C (da)
BR (1) BR9909192A (da)
CA (1) CA2326517C (da)
DE (1) DE59907871D1 (da)
DK (1) DK1083902T3 (da)
ES (1) ES2212547T3 (da)
HU (1) HUP0101246A3 (da)
IL (2) IL137652A0 (da)
NO (1) NO326852B1 (da)
NZ (1) NZ507382A (da)
PL (1) PL192967B1 (da)
PT (1) PT1083902E (da)
TR (1) TR200002786T2 (da)
TW (1) TWI236914B (da)
UY (1) UY25441A1 (da)
WO (1) WO1999049867A1 (da)
ZA (1) ZA200004178B (da)

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CA2352430C (en) 1998-12-01 2008-11-18 Novo Nordisk A/S New pharmaceutical composition and the process for its preparation
AU1548001A (en) 1999-11-24 2001-06-04 Wakamoto Pharmaceutical Co., Ltd. Ophthalmic aqueous preparation
WO2001089523A1 (en) 2000-05-26 2001-11-29 Novo Nordisk A/S New pharmaceutical composition and the process for its preparation
AU2000249111A1 (en) * 2000-05-30 2001-12-11 Dr. Reddy's Research Foundation New pharmaceutical composition and the process for its preparation
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
US7120656B1 (en) 2000-10-04 2006-10-10 Marvell International Ltd. Movable tap finite impulse response filter
WO2002067894A2 (en) * 2001-02-27 2002-09-06 Ranbaxy Laboratories Limited Fast dissolving tablets of cyclooxygenase-2 enzyme inhibitors
EP1250921A1 (en) * 2001-04-21 2002-10-23 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Fast disintegrating meloxicam tablet
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
EP1348436A1 (en) * 2002-03-30 2003-10-01 Boehringer Ingelheim International GmbH Meloxicam suppositories
GB0209257D0 (en) * 2002-04-23 2002-06-05 Novartis Ag Organic compounds
DE10232113A1 (de) * 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
DE10250081A1 (de) * 2002-10-25 2004-05-13 Boehringer Ingelheim Vetmedica Gmbh Wasserlösliche Meloxicam Granulate
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
DK3241550T3 (da) 2002-11-22 2020-08-24 Gruenenthal Gmbh Anvendelse af (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol til behandling af inflammatoriske smerter
US20100297252A1 (en) 2003-03-03 2010-11-25 Elan Pharma International Ltd. Nanoparticulate meloxicam formulations
US8512727B2 (en) 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
PT1603553E (pt) * 2003-03-17 2012-02-03 Japan Tobacco Inc Composições farmacêuticas de inibidores de cetp
KR100620239B1 (ko) * 2004-01-05 2006-09-13 신일제약주식회사 용해도 및 안정성이 향상된 경구투여용 멜록시캄 고형제조성물
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
DE102004021281A1 (de) * 2004-04-29 2005-11-24 Boehringer Ingelheim Vetmedica Gmbh Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin
DE102004030409A1 (de) * 2004-06-23 2006-01-26 Boehringer Ingelheim Vetmedica Gmbh Neue Verwendung von Meloxicam in der Veterinärmedizin
US20060025408A1 (en) * 2004-08-02 2006-02-02 Sundaram Venkataraman Process for the preparation of crystalline form-1 of 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
DK3056492T3 (da) 2004-10-08 2021-12-13 Abbvie Inc Megluminsalt og krystallinke former deraf af et lægemiddel (delafloxacin)
HU227359B1 (en) * 2004-12-18 2011-04-28 Egis Gyogyszergyar Nyilvanosan Mikodi Ruszvunytarsasag Process for producing meloxicam and meloxicam potassium salt of high purity
CA2586288A1 (en) 2004-12-06 2006-06-15 Janssen Pharmaceutica Nv Oral suspension comprising meloxicam
ES2490595T3 (es) 2005-02-17 2014-09-04 Abbott Laboratories Administración transmucosal de composiciones de fármacos para tratar y prevenir trastornos en animales
JP2008540644A (ja) * 2005-07-15 2008-11-20 テバ ファーマシューティカル インダストリーズ リミティド 新規粒質化方法及びそれから生成される粒質物
CA2623201A1 (en) * 2005-09-30 2007-04-12 Boehringer Ingelheim Vetmedica Gmbh Pharmaceutical preparation containing meloxicam
US7572641B2 (en) 2005-11-22 2009-08-11 Teva Pharmaceutical Industries Ltd. Pharmaceutical compositions comprising meloxicam and methods of their preparation
EP1965774A2 (en) * 2005-12-30 2008-09-10 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
KR100791160B1 (ko) * 2006-05-30 2008-01-02 조선대학교산학협력단 멜록시캄의 에탄올아민염 및 이를 함유하는 약제학적조성물
US20070281927A1 (en) * 2006-06-06 2007-12-06 Shanthakumar Tyavanagimatt Anti-inflammatory and analgesic compositions and related methods
WO2009094155A1 (en) * 2008-01-22 2009-07-30 Thar Pharmaceuticals In vivo studies of crystalline forms of meloxicam
TR200809200A1 (tr) 2008-12-01 2009-12-21 Sanovel �La� Sanay� Ve T�Caret Anon�M ��Rket� Meloksikam içeren farmasötik formülasyonlar
ES3037313T3 (en) 2009-10-12 2025-09-30 Boehringer Ingelheim Vetmedica Gmbh Containers for compositions comprising meloxicam
MX2012010077A (es) 2010-03-03 2012-09-12 Boehringer Ingelheim Vetmed Uso de meloxicam para el tratamiento a largo plazo de trastornos musculoesqueleticos en gatos.
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
WO2012009542A2 (en) 2010-07-14 2012-01-19 Kansas State University Research Foundation Methods for alleviating chronic pain and improving performance of cattle undergoing dehorning or castration
US20170281640A1 (en) * 2016-04-04 2017-10-05 Productos Maver, S.A. De C.V. Pharmaceutical Compositions Containing a Muscle Relaxant and a Nonsteroidal Anti-Inflammatory Drugs (NSAID)
WO2020095316A1 (en) * 2018-11-05 2020-05-14 Mylan Laboratories Limited Meloxicam co-crystals
CN113710231A (zh) 2019-04-22 2021-11-26 麦兰专业有限合伙公司 美洛昔康共晶组合物
JP2023547736A (ja) 2020-11-06 2023-11-13 マイラン ラボラトリーズ エルティーディー メロキシカム含有医薬組成物
CN112587497A (zh) * 2020-12-25 2021-04-02 苏州中化药品工业有限公司 一种美洛昔康混悬液胶囊剂及其制备方法

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CA2301304A1 (en) * 1997-08-27 1999-03-04 Hexal Ag New pharmaceutical compositions of meloxicam with improved solubility and bioavailability

Also Published As

Publication number Publication date
HUP0101246A2 (hu) 2002-05-29
AU762322C (en) 2004-02-12
EP1083902B1 (de) 2003-11-26
HUP0101246A3 (en) 2002-08-28
KR20010034698A (ko) 2001-04-25
DE59907871D1 (de) 2004-01-08
CA2326517A1 (en) 1999-10-07
BR9909192A (pt) 2000-12-05
WO1999049867A1 (de) 1999-10-07
EP0945134A1 (de) 1999-09-29
NO20004823L (no) 2000-11-22
TR200002786T2 (tr) 2001-01-22
PL342988A1 (en) 2001-07-16
AU3417199A (en) 1999-10-18
UY25441A1 (es) 1999-11-17
US6869948B1 (en) 2005-03-22
IL137652A (en) 2006-10-05
IL137652A0 (en) 2001-10-31
ES2212547T3 (es) 2004-07-16
ATE254920T1 (de) 2003-12-15
AU762322B2 (en) 2003-06-26
JP2002509886A (ja) 2002-04-02
CN1163231C (zh) 2004-08-25
CA2326517C (en) 2008-06-10
HK1034183A1 (en) 2001-10-19
PL192967B1 (pl) 2006-12-29
EP1083902A1 (de) 2001-03-21
JP3639532B2 (ja) 2005-04-20
ZA200004178B (en) 2002-04-24
AR016197A1 (es) 2001-06-20
NZ507382A (en) 2003-08-29
PT1083902E (pt) 2004-04-30
DK1083902T3 (da) 2004-03-29
CN1295478A (zh) 2001-05-16
KR100589299B1 (ko) 2006-06-14
TWI236914B (en) 2005-08-01
NO20004823D0 (no) 2000-09-26

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