NO333085B1 - Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer. - Google Patents

Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer.

Info

Publication number: NO333085B1
Authority: NO; Norway
Prior art keywords: cram; jam; cells; cell; endothelial
Prior art date: 1999-03-11

Application number

NO20014417A

Other languages

English (en)

Norwegian (no)

Other versions

NO20014417D0 (no

NO20014417L (no

Inventor

Beat Albert Imhof

Michel Aurrand-Lions

Original Assignee

Merck Serono Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-11

Filing date

2001-09-11

Publication date

2013-02-25

2001-09-11 Application filed by Merck Serono Sa filed Critical Merck Serono Sa

2001-09-11 Publication of NO20014417D0 publication Critical patent/NO20014417D0/no

2001-11-12 Publication of NO20014417L publication Critical patent/NO20014417L/no

2013-02-25 Publication of NO333085B1 publication Critical patent/NO333085B1/no

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Toxicology (AREA)
Cell Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Transplantation (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Materials For Medical Uses (AREA)

NO20014417A 1999-03-11 2001-09-11 Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer. NO333085B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP99200746		1999-03-11
PCT/EP2000/002219 WO2000053749A2 (en)	1999-03-11	2000-03-13	Vascular adhesion molecules and modulation of their function

Publications (3)

Publication Number	Publication Date
NO20014417D0 NO20014417D0 (no)	2001-09-11
NO20014417L NO20014417L (no)	2001-11-12
NO333085B1 true NO333085B1 (no)	2013-02-25

Family

ID=8239973

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20014417A NO333085B1 (no)	1999-03-11	2001-09-11	Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer.

Country Status (22)

Country	Link
US (3)	US7393651B2 (de)
EP (2)	EP2292761A1 (de)
JP (2)	JP4836329B2 (de)
CN (2)	CN100469878C (de)
AT (1)	ATE500328T1 (de)
AU (1)	AU782139B2 (de)
BR (1)	BR0008915A (de)
CA (1)	CA2362896C (de)
CZ (1)	CZ303128B6 (de)
DE (1)	DE60045681D1 (de)
EE (1)	EE05497B1 (de)
ES (1)	ES2361905T3 (de)
HU (1)	HU229376B1 (de)
IL (1)	IL145310A0 (de)
IS (1)	IS2819B (de)
MX (1)	MXPA01009110A (de)
NO (1)	NO333085B1 (de)
NZ (1)	NZ514091A (de)
PL (1)	PL207994B1 (de)
RU (1)	RU2244748C2 (de)
WO (1)	WO2000053749A2 (de)
ZA (1)	ZA200107283B (de)

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US8088386B2 (en)	1998-03-20	2012-01-03	Genentech, Inc.	Treatment of complement-associated disorders
US8007798B2 (en)	1997-11-21	2011-08-30	Genentech, Inc.	Treatment of complement-associated disorders
MXPA01009110A (es) *	1999-03-11	2002-08-20	Rmf Dictagene Sa	Moleculas de adhesion vascular y modulacion de su funcion.
GB0100750D0 (en) *	2001-01-11	2001-02-21	Inpharmatica Ltd	Novel proteins
WO2003006673A2 (en) *	2001-07-11	2003-01-23	Texas Biotechnology Corporation	A nucleic acid encoding a human junctional adhesion protein (jam3)
US7642341B2 (en)	2003-12-18	2010-01-05	Merck Serono S.A.	Angiogenesis inhibiting molecules, their selection, production and their use in the treatment of cancer
EP1533617A1 (de)	2003-11-19	2005-05-25	RMF Dictagene S.A.	Angiogenese inhibierende Moleküle, deren Auswahl, Herstellung und Benutzung zur Behandlung und Diagnose von Krebs
DK2500030T4 (en)	2005-11-04	2018-10-29	Genentech Inc	Use of complement pathway inhibitors for the treatment of eye diseases
RU2464030C2 (ru) *	2006-05-26	2012-10-20	Регадо Байосайенсиз, Инк.	Введение противосвертывающей системы reg1
AU2007301599B2 (en)	2006-09-28	2013-01-10	Merck Serono S.A.	Junctional Adhesion Molecule-C (JAM-C) binding compounds and methods of their use
CN106084055A (zh)	2006-11-02	2016-11-09	健泰科生物技术公司	人源化的抗‑d因子抗体
FR2909092B1 (fr) *	2006-11-24	2012-10-19	Pf Medicament	Nouveaux anticorps anti-proliferation
AR066660A1 (es)	2007-05-23	2009-09-02	Genentech Inc	Prevencion y tratamiento de condiciones del ojo asociadas con su complemento
PT2190991T (pt) *	2007-08-06	2019-12-16	Noxxon Pharma Ag	Ácidos nucleicos que se ligam a sdf 1 e a sua utilização
CR20170001A (es)	2008-04-28	2017-08-10	Genentech Inc	Anticuerpos anti factor d humanizados
MX2016001854A (es)	2013-08-12	2016-09-06	Genentech Inc	Composiciones y metodo para tratar condiciones asociadas con el complemento.
SG11201608868PA (en)	2014-05-01	2016-11-29	Genentech Inc	Anti-factor d antibody variants and uses thereof
JP2018536650A (ja)	2015-10-30	2018-12-13	ジェネンテック，インコーポレイテッド	抗ｄ因子抗体変異体コンジュゲート及びその使用
TW201730211A (zh)	2015-10-30	2017-09-01	建南德克公司	抗因子d抗體及結合物

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Publication number	Priority date	Publication date	Assignee	Title
US20030170864A1 (en) *	2000-05-30	2003-09-11	Genentech, Inc.	Secreted and transmembrane polypeptides and nucleic acids encoding the same
SE9604470D0 (sv) *	1996-12-04	1996-12-04	Tamas Bartfai Konsulting Ab	Transmembrane component of tight junction
EP0973892A2 (de) *	1997-03-14	2000-01-26	Human Genome Sciences, Inc.	28 menschliche sekretierte proteine
EP0970111A2 (de) *	1997-03-21	2000-01-12	Genetics Institute, Inc.	Sekretierte proteine und polynukleotide, die für diese kodieren
PT1000149E (pt)	1997-08-01	2007-08-03	Serono Genetics Inst Sa	5' ests para proteínas segregadas identificadas a partir de tecidos do cérebro.
US20030092002A1 (en)	1997-09-17	2003-05-15	Genentech, Inc.	Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1002864A1 (de)	1998-11-10	2000-05-24	Universita' degli studi di Bologna	HIgR und relatierte V Domäne zur Herstellung eines Arzneimittels zur Vorbeugung oder Behandlung von HSV-1, HSV-2 und BHV Infektionen
IL142794A0 (en) *	1998-12-16	2002-03-10	Genentech Inc	Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU2600800A (en) *	1999-03-08	2000-09-28	Genentech Inc.	Promotion or inhibition of angiogenesis and cardiovascularization
MXPA01009110A (es) *	1999-03-11	2002-08-20	Rmf Dictagene Sa	Moleculas de adhesion vascular y modulacion de su funcion.
EP1533617A1 (de) *	2003-11-19	2005-05-25	RMF Dictagene S.A.	Angiogenese inhibierende Moleküle, deren Auswahl, Herstellung und Benutzung zur Behandlung und Diagnose von Krebs
US7642341B2 (en)	2003-12-18	2010-01-05	Merck Serono S.A.	Angiogenesis inhibiting molecules, their selection, production and their use in the treatment of cancer

2000
- 2000-03-13 MX MXPA01009110A patent/MXPA01009110A/es active IP Right Grant
- 2000-03-13 DE DE60045681T patent/DE60045681D1/de not_active Expired - Lifetime
- 2000-03-13 AU AU41051/00A patent/AU782139B2/en not_active Expired
- 2000-03-13 NZ NZ514091A patent/NZ514091A/xx not_active IP Right Cessation
- 2000-03-13 CN CNB008063206A patent/CN100469878C/zh not_active Expired - Lifetime
- 2000-03-13 RU RU2001127668/13A patent/RU2244748C2/ru not_active IP Right Cessation
- 2000-03-13 BR BR0008915-0A patent/BR0008915A/pt not_active Application Discontinuation
- 2000-03-13 HU HU0200606A patent/HU229376B1/hu not_active IP Right Cessation
- 2000-03-13 EE EEP200100472A patent/EE05497B1/xx not_active IP Right Cessation
- 2000-03-13 ES ES00920497T patent/ES2361905T3/es not_active Expired - Lifetime
- 2000-03-13 CN CNA2004100952754A patent/CN1637019A/zh active Pending
- 2000-03-13 WO PCT/EP2000/002219 patent/WO2000053749A2/en not_active Ceased
- 2000-03-13 IL IL14531000A patent/IL145310A0/xx unknown
- 2000-03-13 CZ CZ20013267A patent/CZ303128B6/cs not_active IP Right Cessation
- 2000-03-13 EP EP10181055A patent/EP2292761A1/de not_active Withdrawn
- 2000-03-13 JP JP2000603370A patent/JP4836329B2/ja not_active Expired - Lifetime
- 2000-03-13 EP EP00920497A patent/EP1163337B1/de not_active Expired - Lifetime
- 2000-03-13 AT AT00920497T patent/ATE500328T1/de not_active IP Right Cessation
- 2000-03-13 PL PL350417A patent/PL207994B1/pl not_active IP Right Cessation
- 2000-03-13 CA CA2362896A patent/CA2362896C/en not_active Expired - Lifetime
2001
- 2001-09-03 ZA ZA200107283A patent/ZA200107283B/xx unknown
- 2001-09-10 IS IS6072A patent/IS2819B/is unknown
- 2001-09-11 NO NO20014417A patent/NO333085B1/no not_active IP Right Cessation
2004
- 2004-12-30 US US11/025,834 patent/US7393651B2/en not_active Expired - Fee Related
2008
- 2008-06-12 US US12/137,898 patent/US7670826B2/en not_active Expired - Fee Related
2010
- 2010-02-10 US US12/703,439 patent/US8143056B2/en not_active Expired - Fee Related
- 2010-05-06 JP JP2010106164A patent/JP2010233572A/ja active Pending

Also Published As

Publication number	Publication date
IS6072A (is)	2001-09-10
ZA200107283B (en)	2002-12-24
IL145310A0 (en)	2003-01-12
NO20014417D0 (no)	2001-09-11
JP4836329B2 (ja)	2011-12-14
EP2292761A1 (de)	2011-03-09
US20050266426A1 (en)	2005-12-01
US7393651B2 (en)	2008-07-01
EP1163337A2 (de)	2001-12-19
ES2361905T3 (es)	2011-06-24
NO20014417L (no)	2001-11-12
CZ303128B6 (cs)	2012-04-18
JP2002537837A (ja)	2002-11-12
NZ514091A (en)	2004-01-30
IS2819B (is)	2012-12-15
EE05497B1 (et)	2011-12-15
US8143056B2 (en)	2012-03-27
US20080274970A1 (en)	2008-11-06
HUP0200606A3 (en)	2004-11-29
BR0008915A (pt)	2002-04-09
CN100469878C (zh)	2009-03-18
JP2010233572A (ja)	2010-10-21
WO2000053749A3 (en)	2000-12-14
EP1163337B1 (de)	2011-03-02
PL350417A1 (en)	2002-12-16
HK1044169A1 (en)	2002-10-11
CN1355843A (zh)	2002-06-26
CZ20013267A3 (cs)	2002-02-13
DE60045681D1 (de)	2011-04-14
US7670826B2 (en)	2010-03-02
CN1637019A (zh)	2005-07-13
AU4105100A (en)	2000-09-28
HU229376B1 (en)	2013-11-28
PL207994B1 (pl)	2011-02-28
EE200100472A (et)	2002-12-16
RU2244748C2 (ru)	2005-01-20
MXPA01009110A (es)	2002-08-20
CA2362896A1 (en)	2000-09-14
CA2362896C (en)	2012-07-31
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