NO333085B1 - Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer. - Google Patents

Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer.

Info

Publication number: NO333085B1
Authority: NO; Norway
Prior art keywords: cram; jam; cells; cell; endothelial
Prior art date: 1999-03-11

Application number

NO20014417A

Other languages

English (en)

Norwegian (no)

Other versions

NO20014417L (no

NO20014417D0 (no

Inventor

Beat Albert Imhof

Michel Aurrand-Lions

Original Assignee

Merck Serono Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-11

Filing date

2001-09-11

Publication date

2013-02-25

2001-09-11 Application filed by Merck Serono Sa filed Critical Merck Serono Sa

2001-09-11 Publication of NO20014417D0 publication Critical patent/NO20014417D0/no

2001-11-12 Publication of NO20014417L publication Critical patent/NO20014417L/no

2013-02-25 Publication of NO333085B1 publication Critical patent/NO333085B1/no

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Cell Biology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Transplantation (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Materials For Medical Uses (AREA)

NO20014417A 1999-03-11 2001-09-11 Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer. NO333085B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP99200746		1999-03-11
PCT/EP2000/002219 WO2000053749A2 (fr)	1999-03-11	2000-03-13	Molecules d'adhesion vasculaire et modulation de leur fonction

Publications (3)

Publication Number	Publication Date
NO20014417D0 NO20014417D0 (no)	2001-09-11
NO20014417L NO20014417L (no)	2001-11-12
NO333085B1 true NO333085B1 (no)	2013-02-25

Family

ID=8239973

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20014417A NO333085B1 (no)	1999-03-11	2001-09-11	Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer.

Country Status (22)

Country	Link
US (3)	US7393651B2 (fr)
EP (2)	EP2292761A1 (fr)
JP (2)	JP4836329B2 (fr)
CN (2)	CN100469878C (fr)
AT (1)	ATE500328T1 (fr)
AU (1)	AU782139B2 (fr)
BR (1)	BR0008915A (fr)
CA (1)	CA2362896C (fr)
CZ (1)	CZ303128B6 (fr)
DE (1)	DE60045681D1 (fr)
EE (1)	EE05497B1 (fr)
ES (1)	ES2361905T3 (fr)
HU (1)	HU229376B1 (fr)
IL (1)	IL145310A0 (fr)
IS (1)	IS2819B (fr)
MX (1)	MXPA01009110A (fr)
NO (1)	NO333085B1 (fr)
NZ (1)	NZ514091A (fr)
PL (1)	PL207994B1 (fr)
RU (1)	RU2244748C2 (fr)
WO (1)	WO2000053749A2 (fr)
ZA (1)	ZA200107283B (fr)

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US8088386B2 (en)	1998-03-20	2012-01-03	Genentech, Inc.	Treatment of complement-associated disorders
US8007798B2 (en)	1997-11-21	2011-08-30	Genentech, Inc.	Treatment of complement-associated disorders
JP4836329B2 (ja) *	1999-03-11	2011-12-14	メルクセローノエス．エイ．	血管接着分子およびその機能の調節
GB0100750D0 (en) *	2001-01-11	2001-02-21	Inpharmatica Ltd	Novel proteins
WO2003006673A2 (fr) *	2001-07-11	2003-01-23	Texas Biotechnology Corporation	Acide nucleique codant une proteine d'adhesion jonctionnelle humaine (jam3)
US7642341B2 (en)	2003-12-18	2010-01-05	Merck Serono S.A.	Angiogenesis inhibiting molecules, their selection, production and their use in the treatment of cancer
EP1533617A1 (fr) *	2003-11-19	2005-05-25	RMF Dictagene S.A.	Molécules inhibant l'angiogénèse, leur sélection, production et utilisation pour le traitement et diagnose du cancer
SG10201804008UA (en)	2005-11-04	2018-06-28	Genentech Inc	Use of complement pathway inhibitors to treat ocular diseases
RU2464030C2 (ru) *	2006-05-26	2012-10-20	Регадо Байосайенсиз, Инк.	Введение противосвертывающей системы reg1
CA2663243A1 (fr)	2006-09-28	2008-04-03	Merck Serono S.A.	Composes se liant aux molecules d'adherence jonctionnelles c (jam-c) et procedes d'utilisation correspondants
TW201716437A (zh)	2006-11-02	2017-05-16	建南德克公司	人類化之抗-因子ｄ抗體及其用途
FR2909092B1 (fr) *	2006-11-24	2012-10-19	Pf Medicament	Nouveaux anticorps anti-proliferation
AR066660A1 (es)	2007-05-23	2009-09-02	Genentech Inc	Prevencion y tratamiento de condiciones del ojo asociadas con su complemento
US8772257B2 (en) *	2007-08-06	2014-07-08	Noxxon Pharma Ag	SDF-1 binding nucleic acids and the use thereof
CR20170001A (es)	2008-04-28	2017-08-10	Genentech Inc	Anticuerpos anti factor d humanizados
SG11201601044XA (en)	2013-08-12	2016-03-30	Genentech Inc	Compositions and method for treating complement-associated conditions
AU2015253042A1 (en)	2014-05-01	2016-10-20	Genentech, Inc.	Anti-factor D antibody variants and uses thereof
EP3368090A1 (fr)	2015-10-30	2018-09-05	H. Hoffnabb-La Roche Ag	Conjugués de variants d'anticorps anti-facteur d et leurs utilisations
US10407510B2 (en)	2015-10-30	2019-09-10	Genentech, Inc.	Anti-factor D antibodies and conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000053753A2 (fr) *	1999-03-08	2000-09-14	Genentech, Inc.	Activation ou inhibition de l'angiogenese et de la cardiovascularisation
US20030170864A1 (en) *	2000-05-30	2003-09-11	Genentech, Inc.	Secreted and transmembrane polypeptides and nucleic acids encoding the same
SE9604470D0 (sv) *	1996-12-04	1996-12-04	Tamas Bartfai Konsulting Ab	Transmembrane component of tight junction
AU6552198A (en) *	1997-03-14	1998-09-29	Human Genome Sciences, Inc.	28 human secreted proteins
CA2283631A1 (fr) *	1997-03-21	1998-10-01	Genetics Institute, Inc.	Proteines secretees et polynucleotides les codant
DK1000149T3 (da)	1997-08-01	2007-09-10	Serono Genetics Inst Sa	5'-EST'ere til udskilte proteiner identificeret fra hjernevæv
US20030092002A1 (en)	1997-09-17	2003-05-15	Genentech, Inc.	Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1002864A1 (fr)	1998-11-10	2000-05-24	Universita' degli studi di Bologna	HIgR et domaine V relié pour la préparation d'un médicament pour la prévention et le traitement des infections de HSV-1, HSV-2 et BHV
CA2348757A1 (fr) *	1998-12-16	2000-06-22	Genentech, Inc.	Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci
JP4836329B2 (ja) *	1999-03-11	2011-12-14	メルクセローノエス．エイ．	血管接着分子およびその機能の調節
US7642341B2 (en)	2003-12-18	2010-01-05	Merck Serono S.A.	Angiogenesis inhibiting molecules, their selection, production and their use in the treatment of cancer
EP1533617A1 (fr)	2003-11-19	2005-05-25	RMF Dictagene S.A.	Molécules inhibant l'angiogénèse, leur sélection, production et utilisation pour le traitement et diagnose du cancer

2000
- 2000-03-13 JP JP2000603370A patent/JP4836329B2/ja not_active Expired - Lifetime
- 2000-03-13 WO PCT/EP2000/002219 patent/WO2000053749A2/fr not_active Ceased
- 2000-03-13 DE DE60045681T patent/DE60045681D1/de not_active Expired - Lifetime
- 2000-03-13 CN CNB008063206A patent/CN100469878C/zh not_active Expired - Lifetime
- 2000-03-13 AT AT00920497T patent/ATE500328T1/de not_active IP Right Cessation
- 2000-03-13 PL PL350417A patent/PL207994B1/pl not_active IP Right Cessation
- 2000-03-13 IL IL14531000A patent/IL145310A0/xx unknown
- 2000-03-13 RU RU2001127668/13A patent/RU2244748C2/ru not_active IP Right Cessation
- 2000-03-13 EE EEP200100472A patent/EE05497B1/xx not_active IP Right Cessation
- 2000-03-13 EP EP10181055A patent/EP2292761A1/fr not_active Withdrawn
- 2000-03-13 ES ES00920497T patent/ES2361905T3/es not_active Expired - Lifetime
- 2000-03-13 CN CNA2004100952754A patent/CN1637019A/zh active Pending
- 2000-03-13 HU HU0200606A patent/HU229376B1/hu not_active IP Right Cessation
- 2000-03-13 NZ NZ514091A patent/NZ514091A/xx not_active IP Right Cessation
- 2000-03-13 CZ CZ20013267A patent/CZ303128B6/cs not_active IP Right Cessation
- 2000-03-13 BR BR0008915-0A patent/BR0008915A/pt not_active Application Discontinuation
- 2000-03-13 MX MXPA01009110A patent/MXPA01009110A/es active IP Right Grant
- 2000-03-13 CA CA2362896A patent/CA2362896C/fr not_active Expired - Lifetime
- 2000-03-13 AU AU41051/00A patent/AU782139B2/en not_active Expired
- 2000-03-13 EP EP00920497A patent/EP1163337B1/fr not_active Expired - Lifetime
2001
- 2001-09-03 ZA ZA200107283A patent/ZA200107283B/xx unknown
- 2001-09-10 IS IS6072A patent/IS2819B/is unknown
- 2001-09-11 NO NO20014417A patent/NO333085B1/no not_active IP Right Cessation
2004
- 2004-12-30 US US11/025,834 patent/US7393651B2/en not_active Expired - Fee Related
2008
- 2008-06-12 US US12/137,898 patent/US7670826B2/en not_active Expired - Fee Related
2010
- 2010-02-10 US US12/703,439 patent/US8143056B2/en not_active Expired - Fee Related
- 2010-05-06 JP JP2010106164A patent/JP2010233572A/ja active Pending

Also Published As

Publication number	Publication date
EP1163337A2 (fr)	2001-12-19
ZA200107283B (en)	2002-12-24
NO20014417L (no)	2001-11-12
BR0008915A (pt)	2002-04-09
RU2244748C2 (ru)	2005-01-20
HUP0200606A2 (en)	2002-06-29
DE60045681D1 (de)	2011-04-14
US20080274970A1 (en)	2008-11-06
HU229376B1 (en)	2013-11-28
ES2361905T3 (es)	2011-06-24
AU4105100A (en)	2000-09-28
CA2362896C (fr)	2012-07-31
IS2819B (is)	2012-12-15
US20100267649A1 (en)	2010-10-21
US7670826B2 (en)	2010-03-02
PL350417A1 (en)	2002-12-16
IS6072A (is)	2001-09-10
JP2010233572A (ja)	2010-10-21
HK1044169A1 (en)	2002-10-11
JP4836329B2 (ja)	2011-12-14
EE200100472A (et)	2002-12-16
JP2002537837A (ja)	2002-11-12
CN1637019A (zh)	2005-07-13
CZ20013267A3 (cs)	2002-02-13
MXPA01009110A (es)	2002-08-20
CA2362896A1 (fr)	2000-09-14
IL145310A0 (en)	2003-01-12
WO2000053749A2 (fr)	2000-09-14
EE05497B1 (et)	2011-12-15
HUP0200606A3 (en)	2004-11-29
NO20014417D0 (no)	2001-09-11
CN1355843A (zh)	2002-06-26
EP1163337B1 (fr)	2011-03-02
WO2000053749A3 (fr)	2000-12-14
ATE500328T1 (de)	2011-03-15
US7393651B2 (en)	2008-07-01
AU782139B2 (en)	2005-07-07
US8143056B2 (en)	2012-03-27
EP2292761A1 (fr)	2011-03-09
PL207994B1 (pl)	2011-02-28
CN100469878C (zh)	2009-03-18
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Publication	Publication Date	Title
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Aurrand-Lions et al.	2001	JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells
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WO1998057621A1 (fr)	1998-12-23	Modulation angiogenique par transduction du signal de notch
EP1074618A2 (fr)	2001-02-07	Eléments et procédés permettant la production de cadherines
EP1187917B1 (fr)	2009-10-07	Variante d'epissage de cd44 associee a la polyarthrite rhumatoide
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EP2006299A1 (fr)	2008-12-24	Identification de nouveaux isoformes du récepteur CD160 spécifique de classe I MHC et utilisations associées
EP1646657B1 (fr)	2011-11-16	Anticorps anti-cd44vra et leurs procedes d'utilisation
WO2018138185A1 (fr)	2018-08-02	Nouveaux récepteurs de lymphocytes t et thérapie immunitaire les utilisant pour le traitement du cancer et de maladies infectieuses
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HK1044169B (en)	2011-05-13	Vascular adhesion molecules and modulation of their function
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ZA200109315B (en)	2003-02-12	OX2 receptor homologs.