NO803030L - Nye fosforylmuramylpeptider og fremgangsmaate til deres fremstilling - Google Patents
Nye fosforylmuramylpeptider og fremgangsmaate til deres fremstillingInfo
- Publication number
- NO803030L NO803030L NO803030A NO803030A NO803030L NO 803030 L NO803030 L NO 803030L NO 803030 A NO803030 A NO 803030A NO 803030 A NO803030 A NO 803030A NO 803030 L NO803030 L NO 803030L
- Authority
- NO
- Norway
- Prior art keywords
- lower alkyl
- formula
- cycloalkyl
- hydrogen
- phosphororial
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- -1 Phosphorylmuramyl Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000002434 immunopotentiative effect Effects 0.000 abstract 1
- 125000005740 oxycarbonyl group Chemical group [*:1]OC([*:2])=O 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 125000005156 substituted alkylene group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH921979 | 1979-10-12 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO803030L true NO803030L (no) | 1981-04-13 |
| NO150885B NO150885B (no) | 1984-09-24 |
| NO150885C NO150885C (no) | 1985-01-09 |
Family
ID=4349637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO803030A NO150885C (no) | 1979-10-12 | 1980-10-10 | Analogifremgangsmaate til fremstilling av farmakologisk virksomme muramylpeptider |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4323560A (no) |
| EP (1) | EP0027258B1 (no) |
| JP (1) | JPS5681597A (no) |
| AT (1) | ATE13301T1 (no) |
| AU (1) | AU542377B2 (no) |
| CA (1) | CA1183525A (no) |
| DD (1) | DD155984A5 (no) |
| DE (1) | DE3070649D1 (no) |
| DK (1) | DK429080A (no) |
| ES (1) | ES8106135A1 (no) |
| FI (1) | FI803077A7 (no) |
| GR (1) | GR70671B (no) |
| HU (1) | HU185283B (no) |
| IL (1) | IL61248A (no) |
| NO (1) | NO150885C (no) |
| NZ (1) | NZ195235A (no) |
| PT (1) | PT71906B (no) |
| ZA (1) | ZA806239B (no) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI75578C (fi) * | 1979-07-25 | 1988-07-11 | Ciba Geigy Ag | Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider. |
| US4409209A (en) * | 1979-10-12 | 1983-10-11 | Ciba-Geigy Corporation | Novel phosphorylmuramyl peptides and processes for the manufacture thereof |
| EP0056560A1 (de) * | 1981-01-19 | 1982-07-28 | Ciba-Geigy Ag | Antibiotische Präparate mit gesteigerter Wirksamkeit, Verfahren zu deren Herstellung und Verfahren zur Steigerung der antibiotischen Wirkung von Antibiotika |
| GR78246B (no) * | 1981-01-23 | 1984-09-26 | Ciba Geigy Ag | |
| US5334583A (en) * | 1982-07-23 | 1994-08-02 | Ciba-Geigy Corp. | Use of sugar derivatives for the prophylaxis and treatment of virus infections |
| EP0102319B1 (de) * | 1982-07-23 | 1987-08-19 | Ciba-Geigy Ag | Verwendung von Muramylpeptiden oder deren Analogen zur Prophylaxe und Therapie von Virusinfektionen |
| US5189017A (en) * | 1982-07-23 | 1993-02-23 | Ciba-Geigy Corporation | Use of sugar derivatives for the prophylaxis and treatment of virus infections |
| EP0099578B1 (de) * | 1982-07-23 | 1986-11-12 | Ciba-Geigy Ag | Neue Muramylpeptide und Verfahren zu ihrer Herstellung |
| US4772466A (en) * | 1983-08-22 | 1988-09-20 | Syntex (U.S.A.) Inc. | Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| US4606918A (en) * | 1983-08-22 | 1986-08-19 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| US4933179A (en) * | 1983-08-22 | 1990-06-12 | Syntex (U.S.A.) Inc. | Feline leukemia virus antigen vaccines |
| US4770874A (en) * | 1983-08-22 | 1988-09-13 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| ATE45744T1 (de) * | 1984-07-25 | 1989-09-15 | Ciba Geigy Ag | Phosphatidylverbindungen, verfahren zu ihrer herstellung und ihre verwendung. |
| EP0174912A3 (de) * | 1984-09-13 | 1986-06-04 | Ciba-Geigy Ag | Phosphorverbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung |
| US5106963A (en) * | 1984-12-28 | 1992-04-21 | Miles, Inc., Successor In Interest To Technicon Instruments Corp. | Phospholipid conjugates and their preparation |
| US4873322A (en) * | 1986-01-24 | 1989-10-10 | Ciba-Geigy Corporation | Saccharide derivatives and processes for their manufacture |
| US4916118A (en) * | 1986-08-18 | 1990-04-10 | Board Of Regents, The University Of Texas System | Pharmaceutical administration systems containing chemotactic peptides |
| US5554372A (en) * | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
| US5674911A (en) * | 1987-02-20 | 1997-10-07 | Cytrx Corporation | Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use |
| US5811088A (en) * | 1987-02-20 | 1998-09-22 | Emory University | Antiinfective compounds and methods of use |
| HU212924B (en) * | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| US20020123476A1 (en) * | 1991-03-19 | 2002-09-05 | Emanuele R. Martin | Therapeutic delivery compositions and methods of use thereof |
| US7202225B1 (en) | 1993-10-15 | 2007-04-10 | Emanuele R Martin | Therapeutic delivery compositions and methods of use thereof |
| ATE187154T1 (de) * | 1991-03-19 | 1999-12-15 | Cytrx Corp | Polyoxypropylen/polyoxyethylen copolymere mit verbesserter biologischer aktivität |
| US6933286B2 (en) | 1991-03-19 | 2005-08-23 | R. Martin Emanuele | Therapeutic delivery compositions and methods of use thereof |
| US5622649A (en) * | 1991-06-27 | 1997-04-22 | Emory University | Multiple emulsions and methods of preparation |
| US6488929B2 (en) | 1994-05-23 | 2002-12-03 | Montana State University | Candida albicans phosphomannan complex as a vaccine |
| WO1995031998A1 (en) * | 1994-05-23 | 1995-11-30 | The Research & Development Institute, Inc. | Candida albicans adhesin as a vaccine |
| US6309642B1 (en) | 1997-04-28 | 2001-10-30 | The Research And Development Institute, Inc. | Peptides which mimic candida carbohydrate epitopes and their use in a vaccine |
| US20030072775A1 (en) * | 1997-04-28 | 2003-04-17 | The Research And Development Institute Inc. | Peptides which mimic candida carbohydrate epitopes and their use in a vaccine |
| CN103408635B (zh) * | 2013-06-27 | 2015-06-17 | 深圳翰宇药业股份有限公司 | 一种合成米伐木肽的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH613709A5 (en) | 1975-12-10 | 1979-10-15 | Ciba Geigy Ag | Process for the preparation of glucosamine derivatives |
| US4153684A (en) * | 1976-03-10 | 1979-05-08 | Agence Nationale De Valorisation De La Recherche (Anvar) | Immunizing and anti-infectious adjuvant agents constituted by N-acetyl-muramyl-L-alanyl-D-glutamic acid derivatives |
| US4082736A (en) * | 1976-04-26 | 1978-04-04 | Syntex (U.S.A.) Inc. | Novel immunological adjuvant compounds and methods of preparation thereof |
| US4082735A (en) * | 1976-04-26 | 1978-04-04 | Syntex (U.S.A.) Inc. | Novel immunological adjuvant compounds and methods of preparation thereof |
| FI75578C (fi) * | 1979-07-25 | 1988-07-11 | Ciba Geigy Ag | Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider. |
-
1980
- 1980-09-29 FI FI803077A patent/FI803077A7/fi not_active Application Discontinuation
- 1980-10-06 US US06/194,104 patent/US4323560A/en not_active Expired - Lifetime
- 1980-10-09 ZA ZA00806239A patent/ZA806239B/xx unknown
- 1980-10-09 JP JP14065980A patent/JPS5681597A/ja active Pending
- 1980-10-09 AT AT80106134T patent/ATE13301T1/de not_active IP Right Cessation
- 1980-10-09 EP EP80106134A patent/EP0027258B1/de not_active Expired
- 1980-10-09 DE DE8080106134T patent/DE3070649D1/de not_active Expired
- 1980-10-10 PT PT71906A patent/PT71906B/pt unknown
- 1980-10-10 ES ES495843A patent/ES8106135A1/es not_active Expired
- 1980-10-10 NZ NZ195235A patent/NZ195235A/xx unknown
- 1980-10-10 IL IL61248A patent/IL61248A/xx unknown
- 1980-10-10 CA CA000362214A patent/CA1183525A/en not_active Expired
- 1980-10-10 GR GR63103A patent/GR70671B/el unknown
- 1980-10-10 AU AU63153/80A patent/AU542377B2/en not_active Ceased
- 1980-10-10 NO NO803030A patent/NO150885C/no unknown
- 1980-10-10 HU HU802478A patent/HU185283B/hu unknown
- 1980-10-10 DK DK429080A patent/DK429080A/da not_active Application Discontinuation
- 1980-10-13 DD DD80224546A patent/DD155984A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI803077A7 (fi) | 1981-04-13 |
| IL61248A0 (en) | 1980-12-31 |
| NO150885B (no) | 1984-09-24 |
| HU185283B (en) | 1984-12-28 |
| DE3070649D1 (en) | 1985-06-20 |
| PT71906A (en) | 1980-11-01 |
| AU6315380A (en) | 1981-04-16 |
| AU542377B2 (en) | 1985-02-21 |
| ES495843A0 (es) | 1981-07-16 |
| PT71906B (en) | 1981-08-31 |
| GR70671B (no) | 1982-12-06 |
| DD155984A5 (de) | 1982-07-21 |
| ES8106135A1 (es) | 1981-07-16 |
| NZ195235A (en) | 1983-06-14 |
| ZA806239B (en) | 1981-10-28 |
| EP0027258B1 (de) | 1985-05-15 |
| US4323560A (en) | 1982-04-06 |
| ATE13301T1 (de) | 1985-06-15 |
| CA1183525A (en) | 1985-03-05 |
| IL61248A (en) | 1984-10-31 |
| EP0027258A1 (de) | 1981-04-22 |
| NO150885C (no) | 1985-01-09 |
| JPS5681597A (en) | 1981-07-03 |
| DK429080A (da) | 1981-04-13 |
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