NO824102L - Fremgangsmaate og vektororganisme for styrt akkumulering av klonede heterologe genprodukter i bacillus subtilis - Google Patents

Fremgangsmaate og vektororganisme for styrt akkumulering av klonede heterologe genprodukter i bacillus subtilis

Info

Publication number
NO824102L
NO824102L NO824102A NO824102A NO824102L NO 824102 L NO824102 L NO 824102L NO 824102 A NO824102 A NO 824102A NO 824102 A NO824102 A NO 824102A NO 824102 L NO824102 L NO 824102L
Authority
NO
Norway
Prior art keywords
heterologous gene
subtilis
protein
regulatory signals
plasmid
Prior art date
Application number
NO824102A
Other languages
English (en)
Norwegian (no)
Inventor
Shing Chang
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of NO824102L publication Critical patent/NO824102L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO824102A 1981-04-20 1982-12-07 Fremgangsmaate og vektororganisme for styrt akkumulering av klonede heterologe genprodukter i bacillus subtilis NO824102L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25580481A 1981-04-20 1981-04-20

Publications (1)

Publication Number Publication Date
NO824102L true NO824102L (no) 1982-12-07

Family

ID=22969947

Family Applications (1)

Application Number Title Priority Date Filing Date
NO824102A NO824102L (no) 1981-04-20 1982-12-07 Fremgangsmaate og vektororganisme for styrt akkumulering av klonede heterologe genprodukter i bacillus subtilis

Country Status (12)

Country Link
EP (1) EP0063494B1 (de)
JP (1) JPS58500590A (de)
AT (1) ATE48639T1 (de)
AU (1) AU551529B2 (de)
CA (1) CA1204681A (de)
DE (1) DE3280060D1 (de)
DK (1) DK563082A (de)
ES (2) ES511510A0 (de)
FI (1) FI824238A0 (de)
IL (1) IL65558A0 (de)
NO (1) NO824102L (de)
WO (1) WO1982003633A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR75411B (de) * 1981-04-29 1984-07-16 Biogen Nv
GR81701B (de) * 1983-01-18 1984-12-12 Lilly Co Eli
US4559300A (en) * 1983-01-18 1985-12-17 Eli Lilly And Company Method for using an homologous bacillus promoter and associated natural or modified ribosome binding site-containing DNA sequence in streptomyces
US4595660A (en) * 1983-03-02 1986-06-17 University Of Delaware Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis, mutants and substantially stably transformed mutants of Bacillus subtilis, and methods for utilizing the transformed mutants
US4585739A (en) * 1983-03-07 1986-04-29 E. I. Du Pont De Nemours And Company Plasmid for foreign gene expression in B. subtilis
US4663280A (en) * 1983-05-19 1987-05-05 Public Health Research Institute Of The City Of New York Expression and secretion vectors and method of constructing vectors
US5310675A (en) * 1983-06-24 1994-05-10 Genencor, Inc. Procaryotic carbonyl hydrolases
JPS60137291A (ja) * 1983-12-26 1985-07-20 Takeda Chem Ind Ltd 発現ベクター
EP0221923A4 (de) * 1985-03-29 1990-03-22 Bioteknika International Sekretionsvektor.
IT1186750B (it) * 1985-07-10 1987-12-16 Eniricerche Spa Vettore di clonaggio,molecole di dna ricombinante,ceppi di bacillus subtilis trasformati con dette molecole e metodi per l'espressione di geni eterologhi e produzione e secrezione di proteine codificate da detti geni

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2961658D1 (en) * 1978-05-17 1982-02-18 Thomae Gmbh Dr K Process for preparing human interferon
JPS5564799A (en) * 1978-11-07 1980-05-15 Toray Ind Inc Multi-stage concentration and purification of interferon originated from human fibroblast
NL8000127A (nl) * 1979-01-15 1980-07-17 Harvard College Werkwijze voor het vormen van prokaryotische of eukaryotische proteinen alsmede een daarbij toepasbaar gekoppeld gen.
US4311639A (en) * 1980-07-25 1982-01-19 E. I. Du Pont De Nemours And Company Immunogenic interferon peptides

Also Published As

Publication number Publication date
ES8308586A1 (es) 1983-09-16
ES8403158A1 (es) 1984-03-01
EP0063494B1 (de) 1989-12-13
EP0063494A2 (de) 1982-10-27
FI824238L (fi) 1982-12-09
ES511510A0 (es) 1983-09-16
CA1204681A (en) 1986-05-20
EP0063494A3 (en) 1984-02-22
WO1982003633A1 (en) 1982-10-28
FI824238A7 (fi) 1982-10-09
ES519234A0 (es) 1984-03-01
JPS58500590A (ja) 1983-04-21
FI824238A0 (fi) 1982-12-09
AU8521382A (en) 1982-11-04
DK563082A (da) 1982-12-20
AU551529B2 (en) 1986-05-01
ATE48639T1 (de) 1989-12-15
DE3280060D1 (de) 1990-01-18
IL65558A0 (en) 1982-07-30

Similar Documents

Publication Publication Date Title
EP0036259B1 (de) Verfahren, Vektoren und Organismen für transportierte klonierte heterologe Gen-Produkte in Bacillus subtilis und E.coli
SK62593A3 (en) Method of constructing synthetic leader sequences
CN110607320B (zh) 一种植物基因组定向碱基编辑骨架载体及其应用
KR960013464B1 (ko) 기능성 dna 블록, 이를 함유한 플라즈미드, 플라즈미드에 의해 형질 전환된 효모, 히루딘의 제조방법 및 용도
Sandmeier et al. DNA inversion regions Min of plasmid p15B and Cin of bacteriophage P1: evolution of bacteriophage tail fiber genes
US11053505B2 (en) Cleavable fusion tag for protein overexpression and purification
US5232841A (en) Expression vectors containing a bacillus brevis signal sequence
NO824102L (no) Fremgangsmaate og vektororganisme for styrt akkumulering av klonede heterologe genprodukter i bacillus subtilis
CN119912582B (zh) 单碱基编辑器及其所用脱氨酶与应用
EP0104061B1 (de) Expressionsvektoren
MXPA04005717A (es) Sistema de expresion.
US4940661A (en) Metallothionein transcription control sequences and use thereof
Friesen et al. Nonsense and insertion mutants in the relA gene of E. coli: cloning relA
US4687737A (en) Mammalian suppressor genes
WO1990003438A1 (en) Improved bacterial strains for heterologous gene expression
JP2844191B2 (ja) 外来性プラスミドを安定に有する細菌を用いる蛋白質の製造方法
US4654307A (en) Novel bacteria containing a plasmid having a tRNA code
EP0179786B1 (de) Expressionsvektoren mit hoher kopienanzahl
EP0218652B1 (de) Dns-sequenz
Zuerner et al. Nucleotide sequence analysis of a gene cloned from Leptospira biflexa serovar patoc which complements an argE defect in Escherichia coli
Reha-Krantz [25] Use of genetic analyses to probe structure, function, and dynamics of bacteriophage T4 DNA polymerase
US4816396A (en) Method and vector organism for controlled accumulation of heterologous gene products in bacillus subtilis
KR100538990B1 (ko) 티벡터와 발현벡터로의 기능을 동시에 가지는 플라스미드및 이를 이용한 목적유전자의 발현
EP0441361B1 (de) Verfahren zur Herstellung von Fremdprotein in Escherichia Coli
Grohmann et al. Genes for mitochondrial ribosomal proteins in plants