NO842969L - Fremgangsmaate ved fremstilling av fenylkinolincarboxylsyrer og derivater derav - Google Patents

Fremgangsmaate ved fremstilling av fenylkinolincarboxylsyrer og derivater derav

Info

Publication number
NO842969L
NO842969L NO842969A NO842969A NO842969L NO 842969 L NO842969 L NO 842969L NO 842969 A NO842969 A NO 842969A NO 842969 A NO842969 A NO 842969A NO 842969 L NO842969 L NO 842969L
Authority
NO
Norway
Prior art keywords
phenylkinolincarboxylic
derivatives
acids
procedure
preparation
Prior art date
Application number
NO842969A
Other languages
English (en)
Other versions
NO167510C (no
NO167510B (no
Inventor
David Paul Hesson
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of NO842969L publication Critical patent/NO842969L/no
Publication of NO167510B publication Critical patent/NO167510B/no
Publication of NO167510C publication Critical patent/NO167510C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
    • C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO842969A 1983-07-22 1984-07-20 Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenylkinolincarboxylsyrer NO167510C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51631983A 1983-07-22 1983-07-22
US60510484A 1984-04-30 1984-04-30

Publications (3)

Publication Number Publication Date
NO842969L true NO842969L (no) 1985-01-23
NO167510B NO167510B (no) 1991-08-05
NO167510C NO167510C (no) 1991-11-13

Family

ID=27058797

Family Applications (1)

Application Number Title Priority Date Filing Date
NO842969A NO167510C (no) 1983-07-22 1984-07-20 Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenylkinolincarboxylsyrer

Country Status (16)

Country Link
EP (1) EP0133244B1 (no)
AU (1) AU583793B2 (no)
CA (1) CA1288436C (no)
DE (1) DE3483704D1 (no)
DK (1) DK358784A (no)
ES (1) ES534509A0 (no)
FI (1) FI86987C (no)
GR (1) GR82234B (no)
HK (1) HK142395A (no)
HU (1) HU194832B (no)
IE (1) IE57627B1 (no)
IL (1) IL72471A (no)
NO (1) NO167510C (no)
NZ (1) NZ208966A (no)
PT (1) PT78960B (no)
SU (2) SU1393314A3 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889862A (en) * 1986-08-28 1989-12-26 E. I. Du Pont De Nemours And Company Freeze-dried pharmaceutical compositions of phenylquinoline carboxylic acids
WO1989006227A1 (en) * 1987-12-28 1989-07-13 The Dow Chemical Company Phenoxyphenoxypropionates, intermediates thereof and methods of preparation
US4861783A (en) * 1988-04-26 1989-08-29 E. I. Du Pont De Nemours And Company 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases
US4968702A (en) * 1989-01-17 1990-11-06 American Cyanamid Company Substituted quinolinecarboxylic acids
US4918077A (en) * 1989-01-25 1990-04-17 E. I. Du Pont De Nemours & Co., Inc. 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents
DE3905339A1 (de) * 1989-02-22 1990-09-06 Basf Ag Chinolin-4-carbonsaeurederivate und deren verwendung
US5393891A (en) * 1993-06-08 1995-02-28 The Du Pont Merck Pharmaceutical Company Immunoassay reagents and methods for detecting brequinar and analogs
TW448160B (en) * 1993-12-28 2001-08-01 Merck & Co Inc Novel dicyclohexylamine salt and process for the preparation of leukotriene antagonists
ES2235331T3 (es) * 1997-05-28 2005-07-01 Aventis Pharmaceuticals Inc Compuestos quinolina y quinoxalina que inhiben el factor de crecimiento derivado de plaquetas y/o tirosina quinasas p561ck.
EP0924209B1 (en) * 1997-12-19 2003-05-02 Eli Lilly And Company Hypoglycemic imidazoline compounds
EP1541149A1 (en) * 2002-06-26 2005-06-15 Kyowa Hakko Kogyo Co., Ltd. Phosphodiesterase inhibitor
TW201018662A (en) * 2005-12-12 2010-05-16 Astrazeneca Ab Alkylsulphonamide quinolines
US8232310B2 (en) 2006-12-29 2012-07-31 Georgetown University Targeting of EWS-FLI1 as anti-tumor therapy
NZ700612A (en) 2012-04-12 2016-09-30 Univ Georgetown Methods and compositions for treating ewings sarcoma family of tumors
US9511050B2 (en) 2013-10-24 2016-12-06 Georgetown University Methods and compositions for treating cancer
WO2015077535A2 (en) 2013-11-22 2015-05-28 Genzyme Corporation Novel methods for treating neurodegenerative diseases
CN111777596A (zh) 2014-10-09 2020-10-16 英克特诺治疗公司 吲哚酮化合物及其用途
WO2017172368A1 (en) 2016-03-31 2017-10-05 Oncternal Therapeutics, Inc. Indoline analogs and uses thereof
CN109789127B (zh) 2016-07-29 2022-03-25 英克特诺治疗公司 吲哚啉酮化合物的用途
EP4081215B1 (en) * 2019-12-26 2026-05-20 Ohio State Innovation Foundation METHODS AND COMPOSITIONS FOR INHIBITING DIHYDROOROTATE DEHYDROGENASE

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE502610A (no) * 1950-04-18
US2888346A (en) * 1955-08-22 1959-05-26 Gen Aniline & Film Corp Ultra-violet absorbing compounds

Also Published As

Publication number Publication date
ES8507498A1 (es) 1985-09-01
AU583793B2 (en) 1989-05-11
IE841873L (en) 1985-01-22
EP0133244B1 (en) 1990-12-05
EP0133244A3 (en) 1985-12-11
IL72471A0 (en) 1984-11-30
FI86987C (fi) 1992-11-10
PT78960B (en) 1986-10-20
DE3483704D1 (de) 1991-01-17
AU3085284A (en) 1985-01-24
FI86987B (fi) 1992-07-31
HK142395A (en) 1995-09-15
HUT35248A (en) 1985-06-28
SU1393314A3 (ru) 1988-04-30
NO167510C (no) 1991-11-13
NZ208966A (en) 1986-12-05
SU1452480A3 (ru) 1989-01-15
PT78960A (en) 1984-08-01
NO167510B (no) 1991-08-05
HU194832B (en) 1988-03-28
EP0133244A2 (en) 1985-02-20
DK358784A (da) 1985-01-23
FI842928A0 (fi) 1984-07-20
DK358784D0 (da) 1984-07-20
IL72471A (en) 1988-11-15
ES534509A0 (es) 1985-09-01
FI842928L (fi) 1985-01-23
GR82234B (no) 1984-12-13
CA1288436C (en) 1991-09-03
IE57627B1 (en) 1993-02-10

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